Analysis of the effects of dietary fat on body and skin lipids of hamsters by Raman spectroscopy
Abstract
Raman spectroscopy has previously been applied for studying lipid metabolism. In this study, a ball lens-installed hollow optical fiber Raman probe (BHRP) was used for the noninvasive measurement of skin lipids in hamsters. Our analysis suggested that multi-unsaturated lipids, once converted into a structure containing conjugated double bonds, were oxidized to form peroxides. These results were applied for analyzing lipid metabolism in adipose and skin tissues in hamsters fed tricaprin, saturated medium-chain triglyceride and trilinolein, unsaturated long-chain triglyceride fat diets. Unsaturated lipids formed conjugated structures in skin tissue but not in adipose tissue. Principal component analysis (PCA) revealed that the dietary fat intake correlated strongly with lipid composition in body and skin tissues. Hence, the present results successfully demonstrate that Raman spectroscopy with a BHRP can be a powerful tool for analyzing lipid metabolism.
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Dietary fat intake is closely related to the body's adipose tissue and the lipid composition of the skin.
“Raman spectroscopy studies have shown that dietary fat intake is closely related to the body’s adipose tissue and the lipid composition of the skin [86].”
From Diet and Skin Aging—From the Perspective of Food Nutrition (2020) · cites this paper as [86]
The amount of dietary fat intake is closely related to the lipid composition of the body and skin tissues.
“Besides, the amount of dietary fat intake is closely related to the lipid composition of the body and skin tissues, and insufficient intake of essential fatty acids or abnormal fat metabolism leads to serious skin diseases [86,124].”
From Diet and Skin Aging—From the Perspective of Food Nutrition (2020) · cites this paper as [86]
Insufficient intake of essential fatty acids or abnormal fat metabolism leads to serious skin diseases.
“Besides, the amount of dietary fat intake is closely related to the lipid composition of the body and skin tissues, and insufficient intake of essential fatty acids or abnormal fat metabolism leads to serious skin diseases [86,124].”
From Diet and Skin Aging—From the Perspective of Food Nutrition (2020) · cites this paper as [86]
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Diet and Skin Aging—From the Perspective of Food Nutrition
Cao, C., Xiao, Z., Wu, Y., & Ge, C. (2020) · Nutrients · doi:10.3390/nu12030870 · Cited by 231 · see citing works
- Authors
- Meksiarun, P., Maeda, Y., Hiroi, T., Andriana, B. B., & Sato, H.
- Affiliations
- Kwansei Gakuin University (JP)
- Corresponding author
- Sato, Hidetoshi
- Venue
- The Analyst
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2015
- Volume
- 140
- Issue
- 12
- Pages
- 4238-4244
- ISSN
- 0003-2654 (ISSN-L)
- 1364-5528
- OpenAlex
- W2153282479
- Cited by
- 14
- References
- 43
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 2 · 2023: 1 · 2022: 1 · 2021: 1 · 2020: 2 · 2018: 2 · 2017: 1 · 2016: 1
- FWCI
- 0.81
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Analyst (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Japan Society for the Promotion of Science (24310015)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biophysics › Spectroscopy Techniques in Biomedical and Chemical Research
- Physical Sciences › Chemistry › Analytical Chemistry › Spectroscopy and Chemometric Analyses
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Metabolomics and Mass Spectrometry Studies
- Keywords
- dietary fat, skin lipids, body lipids, lipid metabolism, Raman spectroscopy, ball lens, lipid peroxidation, unsaturated fatty acids, conjugated double bonds, adipose tissue, trilinolein, medium-chain triglycerides, hamster
- MeSH terms
- Animals, Dietary Fats, Feasibility Studies, Cricetinae, Skin, Spectrum Analysis, Raman, Lipid Peroxidation, Lipid Metabolism
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