Recent development of biotin conjugation in biological imaging, sensing, and target delivery

Drug Delivery Systems: Entering the Mainstream

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Avidin

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Multifunctional nanocarriers☆

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Cisplatin Nephrotoxicity: A Review

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Challenges and solutions for the delivery of biotech drugs – a review of drug nanocrystal technology and lipid nanoparticles

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Anthracycline-induced cardiotoxicity: Overview of studies examining the roles of oxidative stress and free cellular iron

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Catechol Polymers for pH-Responsive, Targeted Drug Delivery to Cancer Cells

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Vitamin-mediated targeting as a potential mechanism to increase drug uptake by tumours

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Biotin

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Mechanism-Based Tumor-Targeting Drug Delivery System. Validation of Efficient Vitamin Receptor-Mediated Endocytosis and Drug Release

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The Liposomal Formulation of Doxorubicin

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Gemcitabine–Coumarin–Biotin Conjugates: A Target Specific Theranostic Anticancer Prodrug

Maiti, S., Park, N., Han, J. H., Jeon, H. M., Lee, J. H., Bhuniya, S., Kang, C., & Kim, J. S. (2013) · Journal of the American Chemical Society · doi:10.1021/ja401350x · Cited by 327

The use of nanoparticle-mediated targeted gene silencing and drug delivery to overcome tumor drug resistance

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Bioactive iridium and rhodium complexes as therapeutic agents

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Drug repositioning by structure-based virtual screening

Ma, D.-L., Chan, D. S.-H., & Leung, C.-H. (2013) · Chemical Society Reviews · doi:10.1039/c2cs35357a · Cited by 232

Cloning and Functional Expression of a cDNA Encoding a Mammalian Sodium-dependent Vitamin Transporter Mediating the Uptake of Pantothenate, Biotin, and Lipoate

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Essentials of biorecognition: The (strept)avidin–biotin system as a model for protein–protein and protein–ligand interaction

Wilchek, M., Bayer, E. A., & Livnah, O. (2006) · Immunology Letters · doi:10.1016/j.imlet.2005.10.022 · Cited by 225

Fluorescent dye-doped silica nanoparticles: new tools for bioapplications

Bae, S. W., Tan, W., & Hong, J.-I. (2012) · Chemical Communications · doi:10.1039/c2cc16306c · Cited by 222

An Activatable Theranostic for Targeted Cancer Therapy and Imaging

Bhuniya, S., Maiti, S., Kim, E., Lee, H., Sessler, J. L., Hong, K. S., & Kim, J. S. (2014) · Angewandte Chemie International Edition · doi:10.1002/anie.201311133 · Cited by 215

Mitochondrial Induced and Self-Monitored Intrinsic Apoptosis by Antitumor Theranostic Prodrug: In Vivo Imaging and Precise Cancer Treatment

Kumar, R., Han, J., Lim, H.-J., Ren, W. X., Lim, J.-Y., Kim, J.-H., & Kim, J. S. (2014) · Journal of the American Chemical Society · doi:10.1021/ja510421q · Cited by 214

A Metal‐Based Inhibitor of Tumor Necrosis Factor‐α

Leung, C., Zhong, H., Yang, H., Cheng, Z., Chan, D. S., Ma, V. P., Abagyan, R., Wong, C., & Ma, D. (2012) · Angewandte Chemie International Edition · doi:10.1002/anie.201202937 · Cited by 164

Cucurbit[7]uril Containers for Targeted Delivery of Oxaliplatin to Cancer Cells

Cao, L., Hettiarachchi, G. K., Briken, V., & Isaacs, L. (2013) · Angewandte Chemie International Edition · doi:10.1002/anie.201305061 · Cited by 159

Human Placental Na+-dependent Multivitamin Transporter

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Microarray-based detection and expression analysis of ABC and SLC transporters in drug-resistant ovarian cancer cell lines

Januchowski, R., Zawierucha, P., Andrzejewska, M., Ruciński, M., & Zabel, M. (2012) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2012.11.011 · Cited by 150

Small Targeted Cytotoxics: Current State and Promises from DNA‐Encoded Chemical Libraries

Krall, N., Scheuermann, J., & Neri, D. (2013) · Angewandte Chemie International Edition · doi:10.1002/anie.201204631 · Cited by 148

Intracellular redox-activated anticancer drug delivery by functionalized hollow mesoporous silica nanoreservoirs with tumor specificity

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A Metal‐Based Inhibitor of Tumor Necrosis Factor‐α

Leung, C., Zhong, H., Yang, H., Cheng, Z., Chan, D. S., Ma, V. P., Abagyan, R. A., Wong, C., & Ma, D. (2012) · Angewandte Chemie · doi:10.1002/ange.201202937 · Cited by 142

Molecular and Functional Characterization of the Intestinal Na+-Dependent Multivitamin Transporter

Prasad, P. D., Wang, H., Huang, W. Y., Fei, Y.-J., Leibach, F. H., Devoe, L. D., & Ganapathy, V. (1999) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1999.1213 · Cited by 138

Bioconjugation of Calcium Phosphosilicate Composite Nanoparticles for Selective Targeting of Human Breast and Pancreatic Cancers In Vivo

Barth, B. M., Sharma, R., Altınoğlu, E. İ., Morgan, T. T., Shanmugavelandy, S. S., Kaiser, J. M., McGovern, C. O., Matters, G. L., Smith, J. P., KESTER, M. A., et al. (2010) · ACS Nano · doi:10.1021/nn901297q · Cited by 136

Pharmacogenetics/genomics of membrane transporters in cancer chemotherapy

Huang, Y. S. (2007) · Cancer and Metastasis Reviews · doi:10.1007/s10555-007-9050-6 · Cited by 134

The anti-tumor efficiency of poly(L-glutamic acid) dendrimers with polyhedral oligomeric silsesquioxane cores

Pu, Y., Chang, S., Yuan, H., Wang, G., He, B., & Gu, Z. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.01.082 · Cited by 114

Expression of the coxsackie and adenovirus receptor in human astrocytic tumors and xenografts

Fuxe, J., Liu, L., Malin, S., Philipson, L., Collins, V. P., & Pettersson, R. F. (2002) · International Journal of Cancer · doi:10.1002/ijc.10891 · Cited by 105

Immobilization and surface characterization of NeutrAvidin biotin-binding protein on different hydrogel interlayers

Vermette, P., Gengenbach, T. R., Divisekera, U., Kambouris, P. A., Griesser, H. J., & Meagher, L. (2003) · Journal of Colloid and Interface Science · doi:10.1016/s0021-9797(02)00185-6 · Cited by 105

Biomarkers of cognitive decline in Parkinson's disease

Lin, C., & Wu, R. (2015) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2015.02.010 · Cited by 100

MUC-1 aptamer-conjugated dye-doped silica nanoparticles for MCF-7 cells detection

Cai, L., Chen, Z., Chen, M.-Y., Tang, H., & Pang, D. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2012.09.084 · Cited by 98

Uptake and metabolism of biotin by human peripheral blood mononuclear cells

Zempleni, J., & Mock, D. M. (1998) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1998.275.2.c382 · Cited by 95

A natural product-like inhibitor of NEDD8-activating enzyme

Leung, C., Chan, D. S., Yang, H., Abagyan, R. A., Lee, S. M., Zhu, G., Fong, W. F., & Ma, D. (2011) · Chemical Communications · doi:10.1039/c0cc04927a · Cited by 85

Rational design of biotin–disulfide–coumarin conjugates: a cancer targeted thiol probe and bioimaging

Jung, D., Maiti, S., Lee, J., Lee, J. H., & Kim, J. S. (2014) · Chemical Communications · doi:10.1039/c3cc49790a · Cited by 81

Improved antitumor activity and reduced cardiotoxicity of epirubicin using hepatocyte-targeted nanoparticles combined with tocotrienols against hepatocellular carcinoma in mice

Nasr, M., Nafee, N. A., Saad, H., & Kazem, A. H. (2014) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2014.04.016 · Cited by 77

Design, Synthesis, and Biological Evaluations of Tumor-Targeting Dual-Warhead Conjugates for a Taxoid–Camptothecin Combination Chemotherapy

Vineberg, J. G., Zuniga, E. S., Kamath, A., Chen, Y.-J., Seitz, J. D., & Ojima, I. (2014) · Journal of Medicinal Chemistry · doi:10.1021/jm500631u · Cited by 75

Aiming for the heart: targeted delivery of drugs to diseased cardiac tissue

Scott, R. C., Crabbe, D. L., Krynska, B., Ansari, R., & Kiani, M. F. (2008) · Expert Opinion on Drug Delivery · doi:10.1517/17425247.5.4.459 · Cited by 74

Tumor‐Targeting of EGFR Inhibitors by Hypoxia‐Mediated Activation

Karnthaler‐Benbakka, C., Groza, D., Kryeziu, K., Pichler, V., Roller, A., Berger, W., Heffeter, P., & Kowol, C. R. (2014) · Angewandte Chemie International Edition · doi:10.1002/anie.201403936 · Cited by 72

Multifunctional squalene-based prodrug nanoparticles for targeted cancer therapy

Bui, D. T., Nicolas, J., Maksimenko, A., Desmaële, D., & Couvreur, P. (2013) · Chemical Communications · doi:10.1039/c3cc47427e · Cited by 69

Bufalin loaded biotinylated chitosan nanoparticles: An efficient drug delivery system for targeted chemotherapy against breast carcinoma

Tian, X., Yin, H., Zhang, S., Luo, Y., Xu, K. W., Ma, P., Sui, C., Meng, F., Liu, Y., Jiang, Y., et al. (2014) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2014.05.010 · Cited by 67

Use of biotin targeted methotrexate–human serum albumin conjugated nanoparticles to enhance methotrexate antitumor efficacy

Dinarvand, R., Taheri, Rabbani, Khorramizadeh, M., Borougeni, A. T., Mansoori, & Atyabi, F. (2011) · International Journal of Nanomedicine · doi:10.2147/ijn.s23949 · Cited by 66

Biotin uptake by T47D breast cancer cells: Functional and molecular evidence of sodium-dependent multivitamin transporter (SMVT)

Vadlapudi, A. D., Vadlapatla, R. K., Pal, D., & Mitra, A. K. (2012) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2012.10.047 · Cited by 65

Transport of Biotin in Human Keratinocytes

Grafe, F., Brandsch, M., Wohlrab, W., & Neubert, R. H. H. (2003) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.2003.12058.x · Cited by 63

A biotin-guided fluorescent-peptide drug delivery system for cancer treatment

Kim, T. Y., Jeon, H. M., Le, H. T., Kim, T. W., Kang, C., & Kim, J. S. (2014) · Chemical Communications · doi:10.1039/c4cc02878c · Cited by 59

Advances in targeted therapy for unresectable melanoma: New drugs and combinations

Hao, M., Song, F., Du, X., Wang, G., Yang, Y. P., Chen, K., & Yang, J. (2015) · Cancer Letters · doi:10.1016/j.canlet.2014.12.050 · Cited by 56

Anti‐cAngptl4 Ab‐Conjugated N‐TiO2/NaYF4:Yb,Tm Nanocomposite for Near Infrared‐Triggered Drug Release and Enhanced Targeted Cancer Cell Ablation

Xu, Q. C., Zhang, Y., Tan, M. J., Liu, Y., Yuan, S., Choong, C. S. N., Tan, N. S., & Tan, T. T. Y. (2012) · Advanced Healthcare Materials · doi:10.1002/adhm.201200055 · Cited by 55

Radiolabeling of Poly(lactic- co -glycolic acid) (PLGA) Nanoparticles with Biotinylated F-18 Prosthetic Groups and Imaging of Their Delivery to the Brain with Positron Emission Tomography

Sirianni, R. W., Zheng, M., Patel, T., Shafbauer, T., Zhou, J., Saltzman, W. M., Carson, R. E., & Huang, Y. H. (2014) · Bioconjugate Chemistry · doi:10.1021/bc500315j · Cited by 55

Enhanced therapeutic efficacy of an adenovirus-PEI-bile-acid complex in tumors with low coxsackie and adenovirus receptor expression

Lee, C.-H., Kasala, D., Na, Y., Lee, M. S., Kim, S. W., Jeong, J. H., & Yun, C. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2014.03.060 · Cited by 52

Neuroprotective effects of carvacrol and pomegranate against methotrexate-induced toxicity in rats.

Çelik, F., Göçmez, C., Bozkurt, M., Kaplan, İ., Kamaşak, K., Akıl, E., Dogan, E., Güzel, A., & Uzar, E. (2013) · PubMed · Cited by 50

Biotinylated amphiphile-single walled carbon nanotube conjugate for target-specific delivery to cancer cells

Brahmachari, S., Ghosh, M., Dutta, S., & Das, P. K. (2013) · Journal of Materials Chemistry B · doi:10.1039/c3tb21334j · Cited by 49

Therapeutic Use of Avidin Is Not Hampered by Antiavidin Antibodies in Humans

Petronzelli, F., Pelliccia, A., Anastasi, A. M., Lindstedt, R., Manganello, S., Ferrari, L., Albertoni, C., Leoni, B., Rosi, A., D’Alessio, V., et al. (2010) · Cancer Biotherapy and Radiopharmaceuticals · doi:10.1089/cbr.2010.0797 · Cited by 47

Preliminary studies on the selective accumulation of vitamin-targeted polymers within tumors

Russell-Jones, G. J., McTavish, K. J., & McEwan, J. F. (2010) · Journal of drug targeting · doi:10.3109/10611861003734027 · Cited by 41

Highly sensitive and selective anticancer effect by conjugated HA-cisplatin in non-small cell lung cancer overexpressed with CD44

Quan, Y. H., Kim, B., Park, J., Choi, Y., Choi, Y. H., & Kim, H. K. (2014) · Experimental Lung Research · doi:10.3109/01902148.2014.905656 · Cited by 40

In Vivo Fate of Avidin-Nucleic Acid Nanoassemblies as Multifunctional Diagnostic Tools

Bigini, P., Previdi, S., Casarin, E., Silvestri, D., Violatto, M. B., Facchin, S., Sitia, L., Rosato, A., Zuccolotto, G., Realdon, N., et al. (2013) · ACS Nano · doi:10.1021/nn402669w · Cited by 39

Incorporation of Thrombin Cleavage Peptide into a Protein Cage for Constructing a Protease-Responsive Multifunctional Delivery Nanoplatform

Kang, Y. J., Park, D. C., Shin, H., Park, J., & Kang, S. (2012) · Biomacromolecules · doi:10.1021/bm301339s · Cited by 37

Switchavidin: Reversible Biotin–Avidin–Biotin Bridges with High Affinity and Specificity

Taskinen, B., Zauner, D., Lehtonen, S. I., et al. (2014) · Bioconjugate Chemistry · doi:10.1021/bc500462w · Cited by 36

Anti-αvβ3 antibody guided three-step pretargeting approach using magnetoliposomes for molecular magnetic resonance imaging of breast cancer angiogenesis

Xu, Y., Yan, Wu, Feng, Chen, M., Liu, Hao, Yang, Y., Zhang, Lin, et al. (2013) · International Journal of Nanomedicine · doi:10.2147/ijn.s38678 · Cited by 34

A facile preparation of novel multifunctional vectors by non-covalent bonds for co-delivery of doxorubicin and gene

Ma, M., Yuan, Z., Chen, X. J., Li, F., & Zhuo, R. ‐. (2011) · Acta Biomaterialia · doi:10.1016/j.actbio.2011.11.006 · Cited by 27

2-Iminobiotin Is an Inhibitor of Nitric Oxide Synthases

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Imaging Amyloid Plaque in Alzheimer’s Disease Brain with a Biotinylated Aβ Peptide Radiopharmaceutical Conjugated to an IgG-Avidin Fusion Protein

Sumbria, R. K., Boado, R. J., & Pardridge, W. M. (2012) · Bioconjugate Chemistry · doi:10.1021/bc3001744 · Cited by 19

Streptavidin binding as a model to characterize thiol–ene chemistry-based polyamine surfaces for reversible photonic protein biosensing

Melnik, E., Müellner, P., Bethge, O., Bertagnolli, E., Hainberger, R., & Laemmerhofer, M. (2014) · Chemical Communications · doi:10.1039/c3cc48640k · Cited by 17

Biological colloid engineering: Self-assembly of dipolar ferromagnetic chains in a functionalized biogenic ferrofluid

Ruder, W. C., Hsu, C.-P. D., Edelman, B. D., Schwartz, R. S., & LeDuc, P. R. (2012) · Applied Physics Letters · doi:10.1063/1.4742329 · Cited by 16

Targeting leucine-rich repeat kinase 2 in Parkinson's disease

Chan, S. L., Angeles, D. C., & Tan, E. (2013) · Expert Opinion on Therapeutic Targets · doi:10.1517/14728222.2013.842978 · Cited by 15

Recent Strategies to Develop Innovative Photosensitizers for Enhanced Photodynamic Therapy

Pham, T. C., Nguyen, V.-N., Choi, Y., Lee, S., & Yoon, J. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00381 · Cited by 1,813

Polymeric Nanoparticles for Drug Delivery

Beach, M. A., Nayanathara, U., Gao, Y., Zhang, C., Xiong, Y., Wang, Y., & Such, G. K. (2024) · Chemical Reviews · doi:10.1021/acs.chemrev.3c00705 · Cited by 1,155

Activity‐Based NIR Enzyme Fluorescent Probes for the Diagnosis of Tumors and Image‐Guided Surgery

Li, H., Kim, D., Yao, Q., Ge, H., Chung, J., Fan, J., Wang, J., Peng, X., & Yoon, J. (2021) · Angewandte Chemie International Edition · doi:10.1002/anie.202009796 · Cited by 363

The principles and applications of avidin-based nanoparticles in drug delivery and diagnosis

Jain, A., & Cheng, K. (2017) · Journal of Controlled Release · doi:10.1016/j.jconrel.2016.11.016 · Cited by 304

A facile approach to functionalizing cell membrane-coated nanoparticles with neurotoxin-derived peptide for brain-targeted drug delivery

Chai, Z., Hu, X., Wei, X., Zhan, C., Lu, L., Jiang, K., Su, B., Ruan, H., Ran, D., Fang, R. H., et al. (2017) · Journal of Controlled Release · doi:10.1016/j.jconrel.2017.08.027 · Cited by 253