Finding Essentiality Feasible: Common Questions and Misinterpretations Concerning the “Essential-Use” Concept
Open accessAbstract
The essential-use concept is a tool that can guide the phase-out of per- and polyfluoroalkyl substances (PFAS) and potentially other harmful substances of concern.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The concept of 'essential use' has been proposed to identify which PFAS can be phased out, but there are challenges including a lack of comprehensive data on potential substitutes, the complexity of supply chains, product formulation, and product disposal.
“To mitigate the ban on the entire chemical class of PFAS, the concept of ‘essential use’ has been proposed to identify which PFAS can be phased out. However, there are several challenges inherent in this approach, with these including a lack of comprehensive data on potential substitutes, the complexity of supply chains, product formulation, and product disposal [80].”
From The EU’s Per- and Polyfluoroalkyl Substances (PFAS) Ban: A Case of Policy over Science (2023) · cites this paper as [80]
Split into 2 atoms — 1 confirmed, 1 partially supported, 0 disputed, 0 misattributed, 0 unverifiable. Expand the claim to see per-atom verdicts.
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
An overview of the uses of per- and polyfluoroalkyl substances (PFAS)
Glüge, J., Scheringer, M., Cousins, I. T., DeWitt, J. C., Goldenman, G., Herzke, D., Lohmann, R., Ng, C. A., Trier, X., & Wang, Z. (2020) · Environmental Science: Processes & Impacts · doi:10.1039/d0em00291g · Cited by 2,466 · see citing works
Self-citationHu, X. C., Andrews, D. Q., Lindstrom, A. B., Bruton, T. A., Schaider, L. A., Grandjean, P., Lohmann, R., Carignan, C. C., Blum, A., Balan, S. A., et al. (2016) · Environmental Science & Technology Letters · doi:10.1021/acs.estlett.6b00260 · Cited by 1,333 · see citing works
Self-citationBlum, A., Behl, M., Birnbaum, L. S., Diamond, M. L., Phillips, A. L., Singla, V., Sipes, N. S., Stapleton, H. M., & Venier, M. (2019) · Environmental Science & Technology Letters · doi:10.1021/acs.estlett.9b00582 · Cited by 661 · see citing works
Lohmann, R., Cousins, I. T., DeWitt, J. C., Glüge, J., Goldenman, G., Herzke, D., Lindstrom, A. B., Miller, M. F., Ng, C. A., Patton, S., et al. (2020) · Environmental Science & Technology · doi:10.1021/acs.est.0c03244 · Cited by 452 · see citing works
Self-citationThe concept of essential use for determining when uses of PFASs can be phased out
(2019) · doi:10.1039/c9em00163h · Cited by 313 · see citing works
Self-citationThe Stockholm Convention on Persistent Organic Pollutants
Bilcke, C. V. (2002) · Review of European Community & International Environmental Law · doi:10.1111/1467-9388.00331 · Cited by 274 · see citing works
Montreal Protocol on Substances That Deplete the Ozone Layer
Vaneesha, J. A. I. N. (2023) · Berkshire Publishing Group eBooks · doi:10.2307/jj.9561408.89 · Cited by 213 · see citing works
Schultes, L., Vestergren, R., Volkova, K., Westberg, E., Jacobson, T., & Benskin, J. P. (2018) · Environmental Science: Processes & Impacts · doi:10.1039/c8em00368h · Cited by 193 · see citing works
Golden Gate University Law Review
Black, A., & Hardy, K. (2010) · Cited by 186 · see citing works
Holmquist, H., Schellenberger, S., van der Veen, I., Peters, G. M., Leonards, P. E. G., & Cousins, I. T. (2016) · Environment International · doi:10.1016/j.envint.2016.02.035 · Cited by 170 · see citing works
Self-citationJacobs, M., Malloy, T. F., Tickner, J. A., & Edwards, S. (2015) · Environmental Health Perspectives · doi:10.1289/ehp.1409581 · Cited by 121 · see citing works
Schellenberger, S., Hill, P. J., Levenstam, O., Gillgard, P., Cousins, I. T., Taylor, M., & Blackburn, R. S. (2019) · Journal of Cleaner Production · doi:10.1016/j.jclepro.2019.01.160 · Cited by 96 · see citing works
Self-citationAdvancing Safer Alternatives Through Functional Substitution
Tickner, J. A., Schifano, J. N., Blake, A., Rudisill, C., & Mulvihill, M. J. (2014) · Environmental Science & Technology · doi:10.1021/es503328m · Cited by 91 · see citing works
Persistence, Bioaccumulation, and Toxicity of Halogen-Free Flame Retardants
Waaijers, S. L., Kong, D., Hendriks, H. S., de Wit, C. A., Cousins, I. T., Westerink, R. H. S., Leonards, P. E. G., Kraak, M. H. S., Admiraal, W. A., de Voogt, P., et al. (2012) · Reviews of Environmental Contamination and Toxicology · doi:10.1007/978-1-4614-4717-7_1 · Cited by 87 · see citing works
Self-citation(2000) · United Nations Treaty Series · doi:10.18356/921334a6-en-fr · Cited by 81 · see citing works
Technology Transfer for the Ozone Layer: Lessons for Climate Change
Andersen, S. O., Sarma, K., & Taddonio, K. N. (2007) · Cited by 56 · see citing works
The Architecture of Chemical Alternatives Assessment
Geiser, K., Tickner, J. A., Edwards, S., & Rossi, M. S. (2015) · Risk Analysis · doi:10.1111/risa.12507 · Cited by 33 · see citing works
WELY, E. V. (2017) · Industrial Health · doi:10.2486/indhealth.2017-0124 · Cited by 27 · see citing works
Rodgers, K. M., Covaci, A., Poma, G., Knox, K. E., Allen, J. G., Laurent, J. G. C., Rudel, R. A., & Dodson, R. E. (2020) · Environmental Science & Technology Letters · doi:10.1021/acs.estlett.0c00483 · Cited by 15 · see citing works
Rossi, M. S., Thorpe, B., & Peele, C. (2011) · NEW SOLUTIONS A Journal of Environmental and Occupational Health Policy · doi:10.2190/ns.21.3.f · Cited by 6 · see citing works
Answering the Call for Improved Chemical Alternatives Assessments (CAA)
Tickner, J. A., Dorman, D. C., & Shelton-Davenport, M. K. (2015) · Environmental Science & Technology · doi:10.1021/es505446x · Cited by 5 · see citing works
U.S. and Mexican Regulation of Methyl Bromide: Comparing Pesticide Regulations after NAFTA
Lathrop, K. W., & Bushur-Hallam, C. K. (1995) · University of Oklahoma College of Law - Digital Commons (University of Oklahoma) · Cited by 2 · see citing works
Flagged first, then by citations
1 of the 23 references couldn’t be matched to a known paper.
Research works printed but not linked: 2
- [30]ECHA - European Chemicals Agency (2020) Impacts of REACH restriction and authorisation on substitution in the EU. ECHA-20-R-09-EN. ISBN: 978–92-9481–618-4. Cat. Number: ED-03-20-354-EN-N. DOI: 10.2823/39789. Publ.date: July 2020. Available online at: https://echa.europa.eu/documents/10162/24152346/impact_rest_auth_on_substitution_en.pdf/7c95222f-5f84-57f7-4cba-65b8463c79d4. · DOI
- [31]Coop. The Danish Coop Bans Fluorinated Compounds in All Cosmetics. Press release 09-03-2019. https://www.businesswire.com/news/home/20190309005001/en/Danish-Coop-Bans-Fluorinated-Compounds-Cosmetics.
Cited by
Sorted by citations
Brunn, H., Arnold, G., Körner, W., Rippen, G., Steinhäuser, K. G., & Valentin, I. (2023) · Environmental Sciences Europe · doi:10.1186/s12302-023-00721-8 · Cited by 504 · see citing works
Hale, S. E., Neumann, M., Schliebner, I., Schulze, J., Averbeck, F. S., Castell-Exner, C., Collard, M., Drmač, D., Hartmann, J., Hofman-Caris, C. H. M., et al. (2022) · Environmental Sciences Europe · doi:10.1186/s12302-022-00604-4 · Cited by 108 · see citing works
Self-citationAn Overview of Potential Alternatives for the Multiple Uses of Per- and Polyfluoroalkyl Substances
Figuière, R., Miaz, L. T., Savvidou, E. K., & Cousins, I. T. (2025) · Environmental Science & Technology · doi:10.1021/acs.est.4c09088 · Cited by 108 · see citing works
Self-citationHofstetter, T. B., Bakkour, R., Büchner, D., Eisenmann, H., Fischer, A., Gehre, M., Haderlein, S. B., Höhener, P., Hunkeler, D., Imfeld, G., et al. (2024) · Nature Water · doi:10.1038/s44221-023-00176-4 · Cited by 84 · see citing works
“Assessing and mitigating anthropogenic organic chemicals in the environment is a particularly challenging and debated task 12–14 .”
The EU’s Per- and Polyfluoroalkyl Substances (PFAS) Ban: A Case of Policy over Science
Spyrakis, F., & Dragani, T. A. (2023) · Toxics · doi:10.3390/toxics11090721 · Cited by 78 · see citing works
The Need for Chemical Simplification As a Logical Consequence of Ever-Increasing Chemical Pollution
Fenner, K., & Scheringer, M. (2021) · Environmental Science & Technology · doi:10.1021/acs.est.1c04903 · Cited by 78 · see citing works
Self-citationUntangling the chemical complexity of plastics to improve life cycle outcomes
Law, K. L., Sobkowicz, M. J., Shaver, M. P., & Hahn, M. E. (2024) · Nature Reviews Materials · doi:10.1038/s41578-024-00705-x · Cited by 78 · see citing works
Chemicals in Plastics - A Technical Report
United Nations Environment Programme (2023) · United Nations Environment Programme eBooks · doi:10.59117/20.500.11822/42366 · Cited by 79 · see citing works
Zimmermann, L., Scheringer, M., Geueke, B., Boucher, J. M., Parkinson, L. V., Groh, K. J., & Muncke, J. (2022) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2022.129167 · Cited by 60 · see citing works
Self-citationPrimary plastic polymers: Urgently needed upstream reduction
Baztan, J., Jorgensen, B., Almroth, B. C., Bergmann, M., Farrelly, T. A., Muncke, J., Syberg, K., Thompson, R. C., Boucher, J. M., Olsen, T., et al. (2024) · Cambridge Prisms Plastics · doi:10.1017/plc.2024.8 · Cited by 46 · see citing works
“Additionally, we recommend plastics and their alternatives and substitutes be assessed against the “ essential use concept ” (Cousins et al., 2021) as currently appliedinthe MontrealProtocol.”
Dijk, J. V., Flerlage, H., Beijer, S., Slootweg, J. C., & van Wezel, A. P. (2022) · Chemosphere · doi:10.1016/j.chemosphere.2022.134050 · Cited by 42 · see citing works
“[2] (Arp and Hale, 2019). of this step could change for certain chemicals depending on what uses can be considered essential (Cousins et al., 2021).”
BackgroundOptimizing Chemicals Management in the United States and Canada through the Essential-Use Approach
Bălan, S. A., Andrews, D. Q., Blum, A., Diamond, M. L., Fernández, S. R., Harriman, E., Lindstrom, A. B., Reade, A., Richter, L., Sutton, R., et al. (2023) · Environmental Science & Technology · doi:10.1021/acs.est.2c05932 · Cited by 32 · see citing works
Self-citationBarber, L. B., Miller, S. A., Blaney, L. M., Bradley, P. M., Faunce, K. E., Fleck, J. A., Frick, M., He, K. F., Hollins, R. D., Lewellyn, C., et al. (2025) · Environmental Science & Technology · doi:10.1021/acs.est.4c12167 · Cited by 30 · see citing works
Roy, M. A., Cousins, I. T., Harriman, E., Scheringer, M., Tickner, J. A., & Wang, Z. (2022) · Environmental Science & Technology · doi:10.1021/acs.est.2c03819 · Cited by 25 · see citing works
Self-citationSuffill, E. M., White, M. P., Hale, S. E., & Pahl, S. (2024) · Environmental Sciences Europe · doi:10.1186/s12302-024-00930-9 · Cited by 20 · see citing works
“Cousins et al. [60] give the example of Personal Protective Equipment (PPE) during the COVID-19 pandemic, when there was greater use of PFAS-con-taining PPE than prior to the pandemic because it was deemed that the clear and immediate benefits of better performing PPE outweighed the longer-term…”
BackgroundAlternatives assessment: An analysis on progress and future needs for research and practice
Bechu, A. M., Roy, M. A., Jacobs, M., & Tickner, J. A. (2023) · Integrated Environmental Assessment and Management · doi:10.1002/ieam.4882 · Cited by 17 · see citing works
“…(EUC), which is being developed in the EU to more ef fi ciently phase out chemicals of concern by fi rst focusing on whether the function of the chemical is critical to safety or security and whether existing alternatives could ful fi ll that function (Cousins et al., 2021, 2019; Roy et al., 2022).”
Towards sustainable chemical process design: Revisiting the integration of life cycle assessment
Löwgren, B. H., Hoffmann, C., Vijver, M. G., Steubing, B. R. P., & Cardellini, G. (2025) · Journal of Cleaner Production · doi:10.1016/j.jclepro.2025.144831 · Cited by 15 · see citing works
Figuière, R., Borchert, F., Cousins, I. T., & Ågerstrand, M. (2023) · Environmental Sciences Europe · doi:10.1186/s12302-022-00708-x · Cited by 14 · see citing works
Self-citationA Hazard-Based Approach Enables the Efficient Identification of Chemicals of Concern in Plastics
Hader, J., Wagner, M., Arp, H., Groh, K., Løseth, M. E., Monclús, L., Muncke, J., Zimmermann, L., & Wang, Z.-Y. (2025) · Environmental Science and Technology · doi:10.1021/acs.est.5c02912 · Cited by 12 · see citing works
Self-citationEnvironmental Contaminants of Emerging Concern: Occurrence and Remediation
Prasad, M. N. V., & Elchuri, S. V. (2023) · Chemia, Dydaktyka, Ekologia, Metrologia · doi:10.2478/cdem-2023-0004 · Cited by 11 · see citing works
Exploring the Essential Use Concept for Primary Microplastics Regulation in the EU
Amberg, S., & Mitrano, D. M. (2025) · Environmental Science & Technology · doi:10.1021/acs.est.4c10830 · Cited by 11 · see citing works
From fluorine’s position in the periodic table to PFAS environmental issues
Krafft, M. P. (2025) · Comptes Rendus Chimie · doi:10.5802/crchim.391 · Cited by 10 · see citing works
Karinen, A. K., Tobi, H., Devilee, J. L. A., de Blaeij, A. T., & Gabbert, S. (2024) · Environmental Science & Policy · doi:10.1016/j.envsci.2023.103666 · Cited by 10 · see citing works
Suffill, E. M., Hörberg, S., Hale, S. E., Pahl, S., & White, M. P. (2025) · Journal of Risk Research · doi:10.1080/13669877.2025.2522658 · Cited by 8 · see citing works
“…(e.g. see the similar concept of decent living standards; Rao and Min 2018), as well as over time based on current societal needs (e.g. PFAS used in personal protective equipment like face masks may be rated as more essential and acceptable during health crises like pandemics; Cousins et al. 2021).”
Data Requirements for Implementing the “Essential-Use” Concept in Chemical Legislation
Figuière, R., Wang, Z., Glüge, J., Scheringer, M., Siegrist, A., & Cousins, I. T. (2025) · Environmental Science & Technology · doi:10.1021/acs.est.4c10866 · Cited by 7 · see citing works
Self-citationLarrea‐Gallegos, G., Hofer, S., Hofstätter, N., Punz, B., Watzek, N., Lölsberg, W., Wiench, K., Wohlleben, W., Aguirre, I. G., Nikolakopoulos, A., et al. (2025) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2025.07.030 · Cited by 11 · see citing works
“Different methodologies are implemented: The functional substitution approach prioritizes the question whether identified alternatives could fulfill the function without being critical to safety [48 – 50].”
PFAS and Planetary Boundaries: Global Challenges for Waste Management and Policy Solutions
Weber, R., & Gironés, L. (2026) · Environmental Science & Technology · doi:10.1021/acs.est.5c12334 · Cited by 8 · see citing works
Ameduri, B. M. (2025) · Polymer International · doi:10.1002/pi.70006 · Cited by 5 · see citing works
Chartres, N., Aung, M. T., Norris, S. L., Cooper, C., Bero, L. A., Chou, R., Payne-Sturges, D., Wagner, W. E., Reyes, J. W., Askie, L. M., et al. (2025) · Environmental Science & Technology · doi:10.1021/acs.est.4c08063 · Cited by 6 · see citing works
Implications of grouping per‐ and polyfluoroalkyl substances for contaminated site regulation
Bowles, K. C., Anderson, J. K., Anderson, R. H., Bani, B., Barnes, C. M., Brusseau, M. L., Cousins, I. T., Cushing, P., DiGuiseppi, B., Gray, B., et al. (2024) · Remediation Journal · doi:10.1002/rem.21783 · Cited by 5 · see citing works
Self-citationKramm, J., Völker, C., & Verlag, C. (2023) · Campus Verlag eBooks · doi:10.12907/978-3-593-44902-9 · Cited by 5 · see citing works
Chen, X., Han, W., Chen, J., Xie, H., Xie, Q., Zhu, M., Wang, Z., Cui, Y., & Tang, W. (2024) · Environmental Pollution · doi:10.1016/j.envpol.2024.123312 · Cited by 4 · see citing works
Self-citationTremblay, L. A., Ataria, J. M., Challenger, I., Horswell, J., Baker, V., Langer, E. R., Leckie, A., Champeau, O., Siggins, A., & Northcott, G. L. (2023) · Pollutants · doi:10.3390/pollutants3040034 · Cited by 2 · see citing works
Bechu, A. M., Mittal, K., Xu, K., Yekani, R., Demopoulos, G. P., Moores, A., & Basu, N. (2022) · ACS Sustainable Chemistry & Engineering · doi:10.1021/acssuschemeng.2c03829 · Cited by 2 · see citing works
Chartres, N., & Joglekar, R. (2024) · Environmental Health Perspectives · doi:10.1289/ehp14346 · Cited by 1 · see citing works
Berlinski, S., Calder, B., & Paustenbach, D. J. (2025) · Toxicology Reports · doi:10.1016/j.toxrep.2025.102095 · Cited by 1 · see citing works
“…as a framework to guide the phase-out of PFAS by assessing whether a given use is truly essential, based on three criteria: the function provided, its necessity for health, safety, or critical societal functions, and the availability of technically and economically feasible alternatives [12].”
InfluentialPersistent, Mobile, Toxic: The Effects of Chemical Warning Labels on Public Risk Perception
Suffill, E. M., Vaupotič, N., Schlösser, J., Hale, S. E., White, M. P., & Pahl, S. (2026) · Environmental Science & Technology Letters · doi:10.1021/acs.estlett.5c01231 · Cited by 1 · see citing works
Hader, J. D., Fairén, A. G., Ågerstrand, M., MacLeod, M., & Nowack, B. (2026) · Environmental Science & Technology · doi:10.1021/acs.est.5c15572 · Cited by 1 · see citing works
Zimmermann, L., Scheringer, M., Geueke, B., Boucher, J. M., Parkinson, L. V., Groh, K. J., & Muncke, J. (2022) · SSRN Electronic Journal · doi:10.2139/ssrn.4074219
Self-citationRecommendation: Primary plastic polymers: Urgently needed upstream reduction — R0/PR2
(2024) · Cambridge Prisms Plastics · doi:10.1017/plc.2024.8.pr2
Author comment: Primary plastic polymers: Urgently needed upstream reduction — R0/PR1
Baztan, J. (2024) · Cambridge Prisms Plastics · doi:10.1017/plc.2024.8.pr1
Decision: Primary plastic polymers: Urgently needed upstream reduction — R0/PR3
(2024) · Cambridge Prisms Plastics · doi:10.1017/plc.2024.8.pr3
Figuière, R., Borchert, F., Cousins, I. T., & Ågerstrand, M. (2024) · Figshare · doi:10.6084/m9.figshare.26562454
Self-citationHale, S. E., Neumann, M., Schliebner, I., Schulze, J., Averbeck, F. S., Castell-Exner, C., Collard, M., Drmač, D., Hartmann, J., Hofman-Caris, R., et al. (2022) · Figshare · doi:10.6084/m9.figshare.19327265
Self-citationLöwgren, B. H., Fantke, P., Graf, S., Schlesier, H., Switala, L. H., Cardellini, G., & Vijver, M. G. (2026) · Research Square · doi:10.21203/rs.3.rs-9169627/v1
Jouanneau, W. (2022) · theses.fr (ABES) · doi:10.70675/e97ccda4z438dz4cddzb54cz12df5cf693ed
- Authors
- Cousins, I. T., De Witt, J. C., Glüge, J., Goldenman, G., Herzke, D., Lohmann, R., Miller, M., Ng, C. A., Patton, S., Scheringer, M., Trier, X., & Wang, Z.
- Affiliations
- Stockholm University (SE)
- East Carolina University, Brody School of Medicine, Department of Pharmacology and Toxicology, Greenville, NC 27834, USA
- ETH Zurich (CH)
- Milieu Consulting SPRL, Brussels, Belgium
- NILU (NO)
- University of Rhode Island (US)
- National Institute of Environmental Health Sciences (US)
- University of Pittsburgh (US)
- Commonweal (US)
- Masaryk University (CZ)
- European Environment Agency (DK)
- Corresponding author
- Cousins, Ian T.
- ORCID
- Venue
- Environmental Science: Processes & Impacts
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2021
- Volume
- 23
- Issue
- 8
- Pages
- 1079-1087
- ISSN
- 2050-7887 (ISSN-L)
- 2050-7895
- PMC
- PMC8372848
- OpenAlex
- W3173937427
- Cited by
- 45
- References
- 23
- Citations by year
- 2026: 4 · 2025: 12 · 2024: 11 · 2023: 9 · 2022: 8 · 2021: 1
- FWCI
- 2.83
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Environmental Science Processes & Impacts (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Repository for Publications and Research Data (ETH Zurich) (submittedVersion, cc-by-nc)
- Journal of Media Literacy Education (submittedVersion, cc-by-nc)
- Veřejné služby Informačního systému (Masarykiana Brunensis Universitas) (submittedVersion, cc-by-nc)
- NORA - Norwegian Open Research Archives (submittedVersion, cc-by-nc)
- ETH Zürich Research Collection
- Funders
- Svenska Forskningsrådet Formas (2020-01978)
- National Institute of Environmental Health Sciences (P42ES027706)
- Ministerstvo Školství, Mládeže a Tělovýchovy (CZ.02.1.01/0.0/0.0/15_003/0000469)
- Topics
- Physical Sciences › Environmental Science › Environmental Chemistry › Per- and polyfluoroalkyl substances research
- Physical Sciences › Environmental Science › Environmental Chemistry › Chemistry and Chemical Engineering
- Physical Sciences › Chemical Engineering › Chemical Health and Safety › Chemical Safety and Risk Management
- Keywords
- per- and polyfluoroalkyl substances, substances of concern, chemical management, chemical alternatives, supply chain regulation
- MeSH terms
- Fluorocarbons, Humans
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review