Cited by 173Cellular transport and secretionAutophagy in Disease and TherapyCaveolin-1 and cellular processes

The DOI matches its Crossref record; 102 of the 103 references it cites were found in a registry or an index.

Focusing on clathrin-mediated endocytosis.

Rappoport, Joshua Z.·2008·Biochemical Journal

DOI 10.1042/bj20080474

Open this paper in CoChat — free account

Abstract

Investigations into the mechanisms which regulate entry of integral membrane proteins, and associated ligands, into the cell through vesicular carriers (endocytosis) have greatly benefited from the application of live-cell imaging. Several excellent recent reviews have detailed specific aspects of endocytosis, such as entry of particular cargo, or the different routes of internalization. The aim of the present review is to highlight how advances in live-cell fluorescence microscopy have affected the study of clathrin-mediated endocytosis. The last decade has seen a tremendous increase in the development and dissemination of methods for imaging endocytosis in live cells, and this has been followed by a dramatic shift in the way this critical cellular pathway is studied and understood. The present review begins with a description of the technical advances which have permitted new types of experiment to be performed, as well as potential pitfalls of these new technologies. Subsequently, advances in the understanding of three key endocytic proteins will be addressed: clathrin, dynamin and AP-2 (adaptor protein 2). Although great strides have clearly been made in these areas in recent years, as is often the case, each answer has bred numerous questions. Furthermore, several examples are highlighted where, because of seemingly minor differences in experimental systems, what appear at first to be very similar studies have, at times, yielded vastly differing results and conclusions. Thus this is an exceedingly exciting time to study endocytosis, and this area serves as a clear demonstration of the power of applying live-cell imaging to answer fundamental biological questions.

Integrity signals

Registry

Crossref · 10.1042/bj20080474

Cites

102 of 102 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Three-Dimensional Super-Resolution Imaging by Stochastic Optical Reconstruction Microscopy
Huang, B., Wang, W.-Q., Bates, M., & Zhuang, X. (2008) · Science · doi:10.1126/science.1153529 · Cited by 2,830
Multicolor Super-Resolution Imaging with Photo-Switchable Fluorescent Probes
Bates, M., Huang, B., Dempsey, G. T., & Zhuang, X. (2007) · Science · doi:10.1126/science.1146598 · Cited by 1,507
YOLK PROTEIN UPTAKE IN THE OOCYTE OF THE MOSQUITO AEDES AEGYPTI. L
Roth, T. F., & Porter, K. R. (1964) · The Journal of Cell Biology · doi:10.1083/jcb.20.2.313 · Cited by 1,320
Caveolar endocytosis of simian virus 40 reveals a new two-step vesicular-transport pathway to the ER
Pelkmans, L., Kartenbeck, J., & Helenius, A. (2001) · Nature Cell Biology · doi:10.1038/35074539 · Cited by 1,236
Induction of mutant dynamin specifically blocks endocytic coated vesicle formation.
Damke, H., Baba, T., Warnock, D. E., & Schmid, S. L. (1994) · The Journal of Cell Biology · doi:10.1083/jcb.127.4.915 · Cited by 1,203
Studying protein dynamics in living cells
Lippincott‐Schwartz, J., Snapp, E. L., & Kenworthy, A. K. (2001) · Nature Reviews Molecular Cell Biology · doi:10.1038/35073068 · Cited by 1,192
Curvature of clathrin-coated pits driven by epsin
Ford, M. G. J., Mills, I. G., Peter, B. J., Vallis, Y., Praefcke, G. J. K., Evans, P. R., & McMahon, H. T. (2002) · Nature · doi:10.1038/nature01020 · Cited by 1,019
Development and Use of Fluorescent Protein Markers in Living Cells
Lippincott‐Schwartz, J., & Patterson, G. H. (2003) · Science · doi:10.1126/science.1082520 · Cited by 993
Total Internal Reflection Fluorescence Microscopy in Cell Biology
Axelrod, D. (2001) · Traffic · doi:10.1034/j.1600-0854.2001.21104.x · Cited by 968
Hypertonic media inhibit receptor-mediated endocytosis by blocking clathrin-coated pit formation.
Heuser, J. E., & Anderson, R. G. W. (1989) · The Journal of Cell Biology · doi:10.1083/jcb.108.2.389 · Cited by 924
Endocytosis by random initiation and stabilization of clathrin-coated pits
Ehrlich, M., Boll, W., van Oijen, A., Hariharan, R., Chandran, K., Nibert, M. L., & Kirchhausen, T. (2004) · Cell · doi:10.1016/j.cell.2004.08.017 · Cited by 843
Tubular membrane invaginations coated by dynamin rings are induced by GTP-γS in nerve terminals
Takei, K., McPherson, P. S., Schmid, S. L., & Camilli, P. V. D. (1995) · Nature · doi:10.1038/374186a0 · Cited by 768
Harnessing actin dynamics for clathrin-mediated endocytosis
Kaksonen, M., Toret, C. P., & Drubin, D. G. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1940 · Cited by 706
Imaging actin and dynamin recruitment during invagination of single clathrin-coated pits
Merrifield, C. J., Feldman, M. E., Wan, L., & Almers, W. (2002) · Nature Cell Biology · doi:10.1038/ncb837 · Cited by 691
Clathrin: a unique protein associated with intracellular transfer of membrane by coated vesicles.
Pearse, B. M. (1976) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.73.4.1255 · Cited by 683
Simultaneous Binding of PtdIns(4,5)P 2 and Clathrin by AP180 in the Nucleation of Clathrin Lattices on Membranes
Ford, M. G. J., Pearse, B. M. F., Higgins, M. K., Vallis, Y., Owen, D. J., Gibson, A., Hopkins, C. R., Evans, P. R., & McMahon, H. T. (2001) · Science · doi:10.1126/science.291.5506.1051 · Cited by 659
Biological Basket Weaving: Formation and Function of Clathrin-Coated Vesicles
Brodsky, F. M., Chen, C., Knuehl, C., Towler, M. C., & Wakeham, D. E. (2001) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.17.1.517 · Cited by 637
Coated vesicles from pig brain: Purification and biochemical characterization
Pearse, B. M. F. (1975) · Journal of Molecular Biology · doi:10.1016/s0022-2836(75)80024-6 · Cited by 573
The kinetics of synaptic vesicle recycling measured at single presynaptic boutons
Ryan, T. A., REUTER, H., Wendland, B., Schweizer, F. E., Tsien, R. W., & Smith, S. J. (1993) · Neuron · doi:10.1016/0896-6273(93)90081-2 · Cited by 517
Coupling between Clathrin-Coated-Pit Invagination, Cortactin Recruitment, and Membrane Scission Observed in Live Cells
Merrifield, C. J., Perrais, D., & Zenisek, D. (2005) · Cell · doi:10.1016/j.cell.2005.03.015 · Cited by 476
Analysis of Clathrin-mediated Endocytosis of Epidermal Growth Factor Receptor by RNA Interference
Huang, F., Khvorova, A., Marshall, W., & Sorkin, A. D. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.c400046200 · Cited by 470
Identification of dynamin, a novel mechanochemical enzyme that mediates interactions between microtubules
Shpetner, H. S., & Vallee, R. B. (1989) · Cell · doi:10.1016/0092-8674(89)90027-5 · Cited by 443
Spatial control of coated-pit dynamics in living cells
Gaidarov, I., Santini, F., Warren, R. A., & Keen, J. H. (1999) · Nature Cell Biology · doi:10.1038/8971 · Cited by 427
Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis
Chen, H., Fre, S., Slepnev, V. I., Capua, M. R., Takei, K., Butler, M. H., Di Fiore, P. P., & De Camilli, P. (1998) · Nature · doi:10.1038/29555 · Cited by 425
Differential Distribution of Dynamin Isoforms in Mammalian Cells
Cao, H., Garcı́a, F., & McNiven, M. A. (1998) · Molecular Biology of the Cell · doi:10.1091/mbc.9.9.2595 · Cited by 409
A dynamic actin cytoskeleton functions at multiple stages of clathrin-mediated endocytosis
Yarar, D., Waterman-Storer, C. M., & Schmid, S. L. (2005) · Molecular Biology of the Cell · doi:10.1091/mbc.e04-09-0774 · Cited by 408
Dynamin and its partners: a progress report
Schmid, S. L., McNiven, M. A., & Camilli, P. V. D. (1998) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(98)80066-5 · Cited by 399
Clathrin-dependent endocytosis
Mousavi, S. A., Malerød, L., Berg, T., & Kjeken, R. (2004) · Biochemical Journal · doi:10.1042/bj20031000 · Cited by 398
Clathrin and adaptors
Hirst, J., & Robinson, M. S. (1998) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/s0167-4889(98)00056-1 · Cited by 389
A novel class of clathrin-coated vesicles budding from endosomes.
Stoorvogel, W., Oorschot, V. M. J., & Geuze, H. J. (1996) · The Journal of Cell Biology · doi:10.1083/jcb.132.1.21 · Cited by 358
The dynamin family of mechanoenzymes: pinching in new places
McNiven, M. A., Cao, H., Pitts, K. R., & Yoon, Y. (2000) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(99)01538-8 · Cited by 343
Tandem MS analysis of brain clathrin-coated vesicles reveals their critical involvement in synaptic vesicle recycling
Blondeau, F., Ritter, B., Allaire, P. D., Wasiak, S., Girard, M., Hussain, N. K., Angers, A., Legendre‐Guillemin, V., Roy, L., Boismenu, D., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0308186101 · Cited by 317
Polymerizing Actin Fibers Position Integrins Primed to Probe for Adhesion Sites
Galbraith, C. G., Yamada, K. M., & Galbraith, J. A. (2007) · Science · doi:10.1126/science.1137904 · Cited by 310
Improved preservation and staining of HeLa cell actin filaments, clathrin-coated membranes, and other cytoplasmic structures by tannic acid-glutaraldehyde-saponin fixation.
Maupin, P., & Pollard, T. D. (1983) · The Journal of Cell Biology · doi:10.1083/jcb.96.1.51 · Cited by 298
The dynamins: Redundant or distinct functions for an expanding family of related GTPases?
Urrutia, R. A., Henley, J. R., Cook, T. A., & McNiven, M. A. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.2.377 · Cited by 281
Loss of endocytic clathrin-coated pits upon acute depletion of phosphatidylinositol 4,5-bisphosphate
Zoncu, R., Perera, R. M., Sebastián, R., Nakatsu, F., Chen, H., Balla, T., Ayala, G., Toomre, D. K., & Camilli, P. V. D. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0611733104 · Cited by 280
Role of the AP2 β-Appendage Hub in Recruiting Partners for Clathrin-Coated Vesicle Assembly
Schmid, E. M., Ford, M. G. J., Burtey, A., Praefcke, G. J. K., Peak‐Chew, S., Mills, I. G., Benmerah, A., & McMahon, H. T. (2006) · PLoS Biology · doi:10.1371/journal.pbio.0040262 · Cited by 278
Seeing is believing? A beginners' guide to practical pitfalls in image acquisition
North, A. J. (2006) · The Journal of Cell Biology · doi:10.1083/jcb.200507103 · Cited by 257
Decreased Synaptic Vesicle Recycling Efficiency and Cognitive Deficits in Amphiphysin 1 Knockout Mice
Paolo, G. D., Sankaranarayanan, S., Wenk, M. R., DANIELL, L. W., Perucco, E., Caldarone, B. J., Flavell, R. A., Picciotto, M. R., Ryan, T. A., Cremona, O., et al. (2002) · Neuron · doi:10.1016/s0896-6273(02)00601-3 · Cited by 246
Endocytosis: clathrin-mediated membrane budding
Ungewickell, E. J., & Hinrichsen, L. (2007) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2007.05.003 · Cited by 242
Neural Wiskott Aldrich Syndrome Protein (N-WASP) and the Arp2/3 complex are recruited to sites of clathrin-mediated endocytosis in cultured fibroblasts
Merrifield, C. J., Qualmann, B., Kessels, M. M., & Almers, W. (2004) · European Journal of Cell Biology · doi:10.1078/0171-9335-00356 · Cited by 236
Effects of cytoplasmic acidification on clathrin lattice morphology.
Heuser, J. (1989) · The Journal of Cell Biology · doi:10.1083/jcb.108.2.401 · Cited by 232
Spinning-disk Confocal Microscopy. A Cutting-Edge Tool for Imaging of Membrane Traffic.
Nakano, A. (2002) · Cell Structure and Function · doi:10.1247/csf.27.349 · Cited by 226
Multiple Roles of Auxilin and Hsc70 in Clathrin‐Mediated Endocytosis
Eisenberg, E., & Greene, L. E. (2007) · Traffic · doi:10.1111/j.1600-0854.2007.00568.x · Cited by 217
Dynamin Participates in Focal Extracellular Matrix Degradation by Invasive Cells
Baldassarre, M., Pompeo, A., Beznoussenko, G. V., Castaldi, C., Cortellino, S., McNiven, M. A., Luini, A., & Buccione, R. (2003) · Molecular Biology of the Cell · doi:10.1091/mbc.e02-05-0308 · Cited by 210
Redundant and Distinct Functions for Dynamin-1 and Dynamin-2 Isoforms
Altschuler, Y., Barbas, S. M., Terlecky, L. J., Tang, K., Hardy, S. F., Mostov, K. E., & Schmid, S. L. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.143.7.1871 · Cited by 205
SNX9 Regulates Dynamin Assembly and Is Required for Efficient Clathrin-mediated Endocytosis
Soulet, F., Yarar, D., Leonard, M., & Schmid, S. L. (2005) · Molecular Biology of the Cell · doi:10.1091/mbc.e04-11-1016 · Cited by 203
Amphiphysin, a novel protein associated with synaptic vesicles.
Lichte, B., Veh, R. W., Meyer, H. E., & Kilimann, M. W. (1992) · The EMBO Journal · doi:10.1002/j.1460-2075.1992.tb05317.x · Cited by 202
The Ear of α-Adaptin Interacts with the COOH-terminal Domain of the Eps15 Protein
Benmerah, A., Bègue, B., Dautry‐Varsat, A., & Cerf–Bensussan, N. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.20.12111 · Cited by 191
Clathrin exchange during clathrin-mediated endocytosis
Wu, X., Zhao, X., Baylor, L., Kaushal, S., Eisenberg, E., & Greene, L. E. (2001) · The Journal of Cell Biology · doi:10.1083/jcb.200104085 · Cited by 191
Identification of dynamin 2, an isoform ubiquitously expressed in rat tissues.
Cook, T. A., Urrutia, R. A., & McNiven, M. A. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.2.644 · Cited by 187
Epsin 1 is a Polyubiquitin‐Selective Clathrin‐Associated Sorting Protein
Hawryluk, M. J., Keyel, P. A., Mishra, S., Watkins, S. C., Heuser, J. E., & Traub, L. M. (2006) · Traffic · doi:10.1111/j.1600-0854.2006.00383.x · Cited by 181
Crystal structure of the α appendage of AP-2 reveals a recruitment platform for clathrin-coat assembly
Traub, L. M., Downs, M. A., Westrich, J. L., & Fremont, D. H. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.16.8907 · Cited by 180
In Vivo Dynamics of Clathrin and Its Adaptor-Dependent Recruitment to the Actin-Based Endocytic Machinery in Yeast
Newpher, T. M., Smith, R. P., Lemmon, V., & Lemmon, S. K. (2005) · Developmental Cell · doi:10.1016/j.devcel.2005.04.014 · Cited by 175
A burst of auxilin recruitment determines the onset of clathrin-coated vesicle uncoating
Massol, R., Boll, W., Griffin, A. M., & Kirchhausen, T. L. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0603369103 · Cited by 172
Real-time analysis of clathrin-mediated endocytosis during cell migration
Rappoport, J. Z., & Simon, S. M. (2003) · Journal of Cell Science · doi:10.1242/jcs.00289 · Cited by 172
Self-citation
Spatial dynamics of receptor-mediated endocytic trafficking in budding yeast revealed by using fluorescent alpha-factor derivatives.
Toshima, J. Y., Toshima, J., Kaksonen, M., Martin, A. C., King, D. S., & Drubin, D. (2006) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.0601042103 · Cited by 171
Deep-etch visualization of proteins involved in clathrin assembly.
Heuser, J. E., & Keen, J. H. (1988) · The Journal of Cell Biology · doi:10.1083/jcb.107.3.877 · Cited by 163
Cloning of cDNAs encoding two related 100-kD coated vesicle proteins (alpha-adaptins).
Robinson, M. S. (1989) · The Journal of Cell Biology · doi:10.1083/jcb.108.3.833 · Cited by 159
Clathrin‐ and Dynamin‐Dependent Coated Vesicle Formation from Isolated Plasma Membranes
Miwako, I., Schröter, T., & Schmid, S. L. (2003) · Traffic · doi:10.1111/j.1365-313x.2008.03782.x · Cited by 158
Comparative proteomics of clathrin-coated vesicles
Borner, G. H. H., Harbour, M. E., Hester, S., Lilley, K. S., & Robinson, M. S. (2006) · The Journal of Cell Biology · doi:10.1083/jcb.200607164 · Cited by 157
The autosomal recessive hypercholesterolemia (ARH) protein interfaces directly with the clathrin-coat machinery
Mishra, S. K., Watkins, S. C., & Traub, L. M. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.252630799 · Cited by 155
Interaction of phosphoinositide cycle intermediates with the plasma membrane-associated clathrin assembly protein AP-2
Beck, K. A., & Keen, J. H. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(20)64342-3 · Cited by 146
The Calcineurin-Dynamin 1 Complex as a Calcium Sensor for Synaptic Vesicle Endocytosis
Lai, M. M.-S., Hong, J. J., Ruggiero, A. M., Burnett, P. E., Slepnev, V. I., Camilli, P. V. D., & Snyder, S. H. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.37.25963 · Cited by 145
Synaptojanin Forms Two Separate Complexes in the Nerve Terminal
Micheva, K. D., Kay, B. K., & McPherson, P. S. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.43.27239 · Cited by 142
Clathrin‐Coated Pits: Vive La Différence?
Benmerah, A., & Lamaze, C. (2007) · Traffic · doi:10.1111/j.1600-0854.2007.00585.x · Cited by 142
Cell Membrane Orientation Visualized by Polarized Total Internal Reflection Fluorescence
Sund, S. E., Swanson, J. A., & Axelrod, D. (1999) · Biophysical Journal · doi:10.1016/s0006-3495(99)77066-9 · Cited by 137
Imaging single events at the cell membrane.
Jaiswal, J., & Simon, S. (2007) · Nature Chemical Biology · doi:10.1038/nchembio855 · Cited by 135
Recruitment dynamics of GAK and auxilin to clathrin-coated pits during endocytosis
Lee, D., Wu, X., Eisenberg, E., & Greene, L. E. (2006) · Journal of Cell Science · doi:10.1242/jcs.03092 · Cited by 129
Stoichiometric Interaction of the Epidermal Growth Factor Receptor with the Clathrin-associated Protein Complex AP-2
Sorkin, A. D., McKinsey, T. A., Shih, W. M., Kirchhausen, T. L., & Carpenter, G. F. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.2.619 · Cited by 119
Location and distribution of the light chains in clathrin trimers.
Kirchhausen, T. L., Harrison, S. C., Parham, P., & Brodsky, F. M. (1983) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.80.9.2481 · Cited by 111
Differential evanescence nanometry: live-cell fluorescence measurements with 10-nm axial resolution on the plasma membrane
Saffarian, S., & Kirchhausen, T. (2008) · Biophysical Journal · doi:10.1529/biophysj.107.117234 · Cited by 111
Recruitment of Activated G Protein-coupled Receptors to Pre-existing Clathrin-coated Pits in Living Cells
Scott, M. G. H., Benmerah, A., Muntaner, O., & Marullo, S. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m106586200 · Cited by 105
G protein–coupled receptor/arrestin3 modulation of the endocytic machinery
Santini, F., Gaidarov, I., & Keen, J. H. (2002) · The Journal of Cell Biology · doi:10.1083/jcb.200110132 · Cited by 96
Functional Analysis of AP-2 α and μ2 Subunits
Motley, A. M., Berg, N., Taylor, M. J., Sahlender, D. A., Hirst, J., Owen, D. J., & Robinson, M. S. (2006) · Molecular Biology of the Cell · doi:10.1091/mbc.e06-05-0452 · Cited by 93
Adaptor and Clathrin Exchange at the Plasma Membrane andtrans-Golgi Network
Wu, X., Zhao, X., Puertollano, R., Bonifacino, J. S., Eisenberg, E., & Greene, L. E. (2003) · Molecular Biology of the Cell · doi:10.1091/mbc.e02-06-0353 · Cited by 91
Depletion of GAK/auxilin 2 inhibits receptor-mediated endocytosis and recruitment of both clathrin and clathrin adaptors
Lee, D., Zhao, X., Zhang, F., Eisenberg, E., & Greene, L. E. (2005) · Journal of Cell Science · doi:10.1242/jcs.02548 · Cited by 91
Understanding Living Clathrin-Coated Pits
Rappoport, J. Z., Simon, S. M., & Benmerah, A. (2004) · Traffic · doi:10.1111/j.1398-9219.2004.00187.x · Cited by 88
Self-citation
ATP- and Cytosol-dependent Release of Adaptor Proteins from Clathrin-coated Vesicles: A Dual Role for Hsc70
Hannan, L. A., Newmyer, S. L., & Schmid, S. L. (1998) · Molecular Biology of the Cell · doi:10.1091/mbc.9.8.2217 · Cited by 88
Endocytic Adaptor Molecules Reveal an Endosomal Population of Clathrin by Total Internal Reflection Fluorescence Microscopy
Keyel, P. A., Watkins, S. C., & Traub, L. M. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m312717200 · Cited by 87
Dynamin 1 antisense oligonucleotide treatment prevents neurite formation in cultured hippocampal neurons.
Torre, E. R., McNiven, M. A., & Urrutia, R. A. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)31650-8 · Cited by 84
Non-stoichiometric Relationship between Clathrin Heavy and Light Chains Revealed by Quantitative Comparative Proteomics of Clathrin-coated Vesicles from Brain and Liver
Girard, M., Allaire, P. D., McPherson, P. S., & Blondeau, F. (2005) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m500043-mcp200 · Cited by 80
Polarized Fluorescence Resonance Energy Transfer Microscopy
Mattheyses, A. L., Hoppe, A. D., & Axelrod, D. (2004) · Biophysical Journal · doi:10.1529/biophysj.103.036194 · Cited by 77
Clathrin is Important for Normal Actin Dynamics and Progression of Sla2p‐Containing Patches During Endocytosis in Yeast
Newpher, T. M., & Lemmon, S. (2006) · Traffic : the International Journal of Intracellular Transport · doi:10.1111/j.1600-0854.2006.00410.x · Cited by 77
Dynamics of clathrin and adaptor proteins during endocytosis
Rappoport, J. Z., Kemal, S., Benmerah, A., & Simon, S. M. (2006) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00160.2006 · Cited by 72
Self-citation
The AP-2 Complex Is Excluded from the Dynamic Population of Plasma Membrane-associated Clathrin
Rappoport, J. Z., Taha, B. W., Lemeer, S., Benmerah, A., & Simon, S. M. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.c300390200 · Cited by 71
Self-citation
Clathrin and coated vesicle proteins Immunological characterization.
Keen, J. H., Willingham, M. C., & Pastan, I. H. (1981) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)69816-9 · Cited by 59
Movement of Plasma‐Membrane‐Associated Clathrin Spots Along the Microtubule Cytoskeleton
Rappoport, J. Z., Taha, B. W., & Simon, S. M. (2003) · Traffic · doi:10.1034/j.1600-0854.2003.00100.x · Cited by 56
Self-citation
Deep-etch visualization of 27S clathrin: a tetrahedral tetramer.
Heuser, J. E., Keen, J. H., Amende, L. M., Lippoldt, R. E., & Prasad, K. (1987) · The Journal of Cell Biology · doi:10.1083/jcb.105.5.1999 · Cited by 52
Clathrin-mediated endocytosis before fluorescent proteins
Roth, M. G. (2005) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1783 · Cited by 49
The Proline-rich Domain of Dynamin-2 Is Responsible for Dynamin-dependent in Vitro Potentiation of Endothelial Nitric-oxide Synthase Activity via Selective Effects on Reductase Domain Function
Cao, S., Yao, J. Z., & Shah, V. H. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m212546200 · Cited by 49
Analysis of the AP-2 adaptor complex and cargo during clathrin-mediated endocytosis
Rappoport, J. Z., Benmerah, A., & Simon, S. M. (2005) · Traffic · doi:10.1111/j.1600-0854.2005.00280.x · Cited by 41
Self-citation
Structure determination of clathrin coats to subnanometer resolution by single particle cryo-electron microscopy
Fotin, A., Kirchhausen, T. L., Grigorieff, N., Harrison, S. C., Walz, T., & Cheng, Y. (2006) · Journal of Structural Biology · doi:10.1016/j.jsb.2006.07.001 · Cited by 40
Differential Control of Clathrin Subunit Dynamics Measured with EW‐FRAP Microscopy
Loerke, D., Wienisch, M., Kochubey, O., & Klingauf, J. (2005) · Traffic · doi:10.1111/j.1600-0854.2005.00329.x · Cited by 36
A pre-embedding immunogold approach for detection of synaptic endocytic proteins in situ
Evergren, E., Tomilin, N. V., Vasylieva, E., Sergeeva, V., Bloom, O., Gad, H., Capani, F., & Shupliakov, O. (2004) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2003.12.010 · Cited by 33
Endocytosis: Curvature to the ENTH Degree
Nossal, R., & Zimmerberg, J. J. (2002) · Current Biology · doi:10.1016/s0960-9822(02)01289-7 · Cited by 33
The Conserved Isoleucine–Valine–Phenylalanine Motif Couples Activation State and Endocytic Functions of β‐Arrestins
Burtey, A., Schmid, E. M., Ford, M. G. J., Rappoport, J. Z., Scott, M. G. H., Marullo, S., Simon, S. M., McMahon, H. T., & Benmerah, A. (2007) · Traffic · doi:10.1111/j.1600-0854.2007.00578.x · Cited by 33
Self-citation
Dynamin, a GTPase Involved in the Initial Stages of Endocytosis
Vallee, R. B., Herskovits, J. S., Aghajanian, J. G., Burgess, C. C., & Shpetner, H. S. (2007) · Novartis Foundation symposium · doi:10.1002/9780470514450.ch12 · Cited by 31
Exchange of clathrin, AP2 and epsin on clathrin-coated pits in permeabilized tissue culture cells
Yim, Y.-I., Scarselletta, S., Zang, F., Wu, X., Lee, D., Kang, Y.-S., Eisenberg, E., & Greene, L. E. (2005) · Journal of Cell Science · doi:10.1242/jcs.02356 · Cited by 31
Dynamics of Dynamin during Clathrin Mediated Endocytosis in PC12 Cells
Rappoport, J. Z., Heyman, K. P., Kemal, S., & Simon, S. M. (2008) · PLoS ONE · doi:10.1371/journal.pone.0002416 · Cited by 30
Self-citation
Forthcoming papers and review topics
Miwako, I., Schröter, T., & Schmid, S. L. (2003) · Traffic · doi:10.1034/j.1600-0854.2003.00092.x · Cited by 16
Impact of live cell imaging on coated vesicle research.
Wessels, E., & Simpson, J. C. (2007) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2007.07.002 · Cited by 11

Sorted by citations

Endocytosis of nanomedicines
Sahay, G., Alakhova, D. Y., & Kabanov, A. V. (2010) · Journal of Controlled Release · doi:10.1016/j.jconrel.2010.01.036 · Cited by 2,181
Insight into Cellular Uptake and Intracellular Trafficking of Nanoparticles
Foroozandeh, P., & Aziz, A. A. (2018) · Nanoscale Research Letters · doi:10.1186/s11671-018-2728-6 · Cited by 1,438
Cellular Uptake, Intracellular Trafficking, and Cytotoxicity of Nanomaterials
Zhao, F., Zhao, Y., Liu, Y., Chang, X., Chen, C., & Zhao, Y. (2011) · Small · doi:10.1002/smll.201100001 · Cited by 1,206
A High Precision Survey of the Molecular Dynamics of Mammalian Clathrin-Mediated Endocytosis
Taylor, M. J., Perrais, D., & Merrifield, C. J. (2011) · PLoS Biology · doi:10.1371/journal.pbio.1000604 · Cited by 754
Lipids and Lipid Derivatives for RNA Delivery
Zhang, Y., Sun, C., Wang, C., Jankovic, K. E., & Dong, Y. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00244 · Cited by 649

See all 173

Authors: Rappoport, J. Z.
Affiliations: University of Birmingham (GB)
Corresponding author: Rappoport, Joshua Z.
ORCID: Rappoport, Joshua Z.
Venue: Biochemical Journal
Publisher: Portland Press Ltd.
Published: 2008-05-28
Volume: 412
Issue: 3
Pages: 415-423
ISSN: 0264-6021 (ISSN-L)
1470-8728
DOI: 10.1042/bj20080474
OpenAlex: W2012515487
Cited by: 172
References: 103
Citations by year: 2025: 4 · 2024: 8 · 2023: 5 · 2022: 6 · 2021: 6 · 2020: 14 · 2019: 6 · 2018: 5 · 2017: 16 · 2016: 11 · 2015: 10 · 2014: 12 · 2013: 9 · 2012: 14
FWCI: 1.24
Type: journal article
Language: en
Open access: closed
Locations: Biochemical Journal (publishedVersion)
PubMed (publishedVersion)
University of Birmingham Research Portal (University of Birmingham) (submittedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular transport and secretion
Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Autophagy in Disease and Therapy
Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Caveolin-1 and cellular processes
Keywords: clathrin-mediated endocytosis, live-cell fluorescence microscopy, clathrin, dynamin, vesicle trafficking, endocytic proteins
MeSH terms: Animals, Clathrin, Endocytosis, Humans, Microscopy, Fluorescence, Protein Transport, Clathrin-Coated Vesicles, Adaptor Protein Complex 2, Dynamins

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Focusing on clathrin-mediated endocytosis.

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks