Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networks

Magnuson, Brian, Ekim, Bilgen, Fingar, Diane C.·2012·Biochemical Journal

Cited by (1,000)

Items 301–400 of 1,000

  1. Biomarker-Directed Therapy of Squamous Carcinomas of the Head and Neck: Targeting PI3K/PTEN/mTOR Pathway
    F. Christopher Holsinger, Sarina Anne Piha-Paul, Filip Jankú, David S. Hong, Johnique T. Atkins, Apostolia Maria Tsimberidou, Razelle Kurzrock · 2013 · Journal of Clinical Oncology
  2. Mitochondrial Dysfunction Plus High-Sugar Diet Provokes a Metabolic Crisis That Inhibits Growth
    Esko Kemppainen, Jack Morikka, Görkem Garipler, Tea Tuomela, Essi Kiviranta, Tomoyoshi Soga, Cory D. Dunn, Howard Trevor Jacobs · 2016 · PLoS ONE
  3. Identification of novel FAK and S6K1 dual inhibitors from natural compounds via ADMET screening and molecular docking
    Varadharajan Thiyagarajan, Shin-Hung Lin, Yu-Chuan Chang, Ching‐Feng Weng · 2016 · Biomedicine & Pharmacotherapy
  4. Integrative biomarker analyses indicate etiological variations in hepatocellular carcinoma.
    A. Zhu, David J. Chen, Wei He, M. Kanai, M. Voi, Li-Tzong Chen, B. Daniele, J. Furuse, Yoon-Koo Kang, R. Poon et al. · 2016 · Journal of Hepatology
  5. Different interactomes for p70‐S6K1 and p54‐S6K2 revealed by proteomic analysis
    Isadora Carolina Betim Pavan, Sami Yokoo, Daniela C. Granato, Letícia Meneguello, Carolina Moretto Carnielli, Mariana Rosolen Tavares, Camila Libardi do Amaral, Lidia Freitas, Adriana Franco Paes Leme, Augusto Ducati Luchessi et al. · 2016 · PROTEOMICS
  6. Phosphatidic acid: biosynthesis, pharmacokinetics, mechanisms of action and effect on strength and body composition in resistance-trained individuals
    Peter Bond · 2017 · Nutrition & Metabolism
  7. Post-transcriptional gene regulation regulates germline stem cell to oocyte transition during Drosophila oogenesis
    Patrick Blatt, Elliot Todd Martin, Shane M. Breznak, Prashanth Rangan · 2019 · Current topics in developmental biology/Current Topics in Developmental Biology
  8. Translation Regulation by eIF2α Phosphorylation and mTORC1 Signaling Pathways in Non-Communicable Diseases (NCDs)
    Tiffany J. Rios-Fuller, Mélanie Mahé, Beth Walters, Dounia Abbadi, Sandra Pérez-Baos, Abhilash Gadi, John J. Andrews, Olga Katsara, C. Theresa Vincent, Robert J. Schneider · 2020 · International Journal of Molecular Sciences
  9. The tip of the iceberg: emerging roles of TORC1, and its regulatory functions in plant cells
    Javier Martínez Pacheco, María Victoria Canal, Cintia Mariana Pereyra, Elina Welchen, Giselle M.A. Martínez-Noël, José M. Estevez · 2020 · Journal of Experimental Botany
  10. Chemical and Structural Strategies to Selectively Target mTOR Kinase
    Chiara Borsari, Martina De Pascale, Matthias P. Wymann · 2021 · ChemMedChem
  11. Dynamic regulation of ribosome levels and translation during development
    Shane M. Breznak, Noor M. Kotb, Prashanth Rangan · 2022 · Seminars in Cell and Developmental Biology
  12. S6 Kinase- and β-TrCP2-Dependent Degradation of p19Arf Is Required for Cell Proliferation
    Tadashi Nakagawa, Takaaki Araki, Makiko Nakagawa, Atsushi Hirao, Michiaki Unno, Keiko Nakayama · 2015 · Molecular and Cellular Biology
  13. Nutrigenomics in Arma chinensis: Transcriptome Analysis of Arma chinensis Fed on Artificial Diet and Chinese Oak Silk Moth Antheraea pernyi Pupae
    Dongdong Zou, Thomas A. Coudron, Chenxi Liu, Lisheng Zhang, Mengqing Wang, Hongyin Chen · 2013 · PLoS ONE
  14. Crystal structures of S6K1 provide insights into the regulation mechanism of S6K1 by the hydrophobic motif
    Jianchuan Wang, Chen Zhong, Fang Wang, Fangfang Qu, Jianping Ding · 2013 · Biochemical Journal
  15. Bidirectional manipulation of mTOR signaling disrupts socially mediated vocal learning in juvenile songbirds
    Somayeh Ahmadiantehrani, Sarah E. London · 2017 · Proceedings of the National Academy of Sciences
  16. Antiphospholipid antibody‐induced cellular responses depend on epitope specificity : implications for treatment of antiphospholipid syndrome
    Nadine Müller‐Calleja, Anne Hollerbach, Friederike Häuser, Antje Canisius, Carolin Orning, Karl Johannes Lackner · 2017 · Journal of Thrombosis and Haemostasis
  17. mTOR Pathway is Involved in Energy Homeostasis Regulation as a Part of the Gut–Brain Axis
    Verónica Pena-León, Raquel Pérez-Lois, Luisa Maria Seoane · 2020 · International Journal of Molecular Sciences
  18. PHLPPing the Script: Emerging Roles of PHLPP Phosphatases in Cell Signaling
    Timothy R. Baffi, Ksenya Cohen‐Katsenelson, Alexandra C. Newton · 2020 · The Annual Review of Pharmacology and Toxicology
  19. OsPPR939, a nad5 splicing factor, is essential for plant growth and pollen development in rice
    Peng Zheng, Yujun Liu, Xuejiao Liu, Yuqing Huang, Feng Sun, Wenyi Wang, Hao Chen, Mehmood Jan, Cuicui Zhang, Yue Yuan et al. · 2021 · Theoretical and Applied Genetics
  20. Abnormal Insulin-like Growth Factor 1 Signaling Regulates Neuropathic Pain by Mediating the Mechanistic Target of Rapamycin-Related Autophagy and Neuroinflammation in Mice
    Xin Chen, Yue Le, Wanyou He, Jian He, Yunhua Wang, Lei Zhang, Qingming Xiong, Xueqin Zheng, Ke‐Xuan Liu, Hanbing Wang · 2021 · ACS Chemical Neuroscience
  21. Telmisartan Restricts Chikungunya Virus Infection In Vitro and In Vivo through the AT1/PPAR-γ/MAPKs Pathways
    Saikat De, Prabhudutta Mamidi, Soumyajit Ghosh, Supriya Suman Keshry, Chandan Mahish, Sweta Smita Pani, Eshna Laha, Amrita Ray, Ankita Datey, Sanchari Chatterjee et al. · 2021 · Antimicrobial Agents and Chemotherapy
  22. A marriage of two “Methusalem” drugs for the treatment of psoriasis?
    Hartmut H. Glossmann, Norbert Reider · 2013 · Dermato-Endocrinology
  23. Association between insulin-like growth factor-1 receptor (IGF1R) negativity and poor prognosis in a cohort of women with primary breast cancer
    Kristina E. Aaltonen, Ann H. Rosendahl, Hans Olsson, Per Malmström, Linda Werner Hartman, Mårten Fernö · 2014 · BMC Cancer
  24. eIF4A inactivates TORC1 in response to amino acid starvation
    Foivos-Filippos Tsokanos, M. Albert, C. Demetriades, Kerstin Spirohn, M. Boutros, Aurelio A. Teleman · 2016 · EMBO Journal
  25. Partial Loss of the Glutamate Transporter GLT-1 Alters Brain Akt and Insulin Signaling in a Mouse Model of Alzheimer's Disease
    Kole D. Meeker, James S. Meabon, David G. Cook · 2015 · Journal of Alzheimer s Disease
  26. The metabolic characteristic of decidual immune cells and their unique properties in pregnancy loss*
    Tao Zhang, Hui‐Hui Shen, Xueyun Qin, Ming‐Qing Li · 2022 · Immunological Reviews
  27. Crosstalk between MiRNAs/lncRNAs and PI3K/AKT signaling pathway in diabetes mellitus: Mechanistic and therapeutic perspectives
    Seyed Mohsen Aghaei Zarch · 2024 · Non-coding RNA Research
  28. Replacement of fish meal with cottonseed protein concentrate in Chinese mitten crab (Eriocheir sinensis): Nutrient digestibility, growth performance, free amino acid profile, and expression of genes related to nutrient metabolism
    Xinting Liu, Danyang Zou, Yizhu Wang, Yutong Zhuang, Yang Liu, Yanyu Li, Zhenzhu Sun, Chaoxia Ye · 2024 · Animal nutrition
  29. Direct imaging of the recruitment and phosphorylation of S6K1 in the mTORC1 pathway in living cells
    Abdullah R. Ahmed, Raymond J. Owens, Christopher D. Stubbs, Anthony William Parker, Richard B. Hitchman, Rahul B. Yadav, Maud Dumoux, Chris R. Hawes, Stanley W. Botchway · 2019 · Scientific Reports
  30. Prophylactic effect of physical exercise on Aβ1–40-induced depressive-like behavior: Role of BDNF, mTOR signaling, cell proliferation and survival in the hippocampus
    Julia Macedo Rosa, Francis L. Pazini, Gislaine Olescowicz, Anderson Camargo, Morgana Moretti, Joana Gil‐Mohapel, Ana Lúcia S. Rodrigues · 2019 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
  31. Upregulation of CENPM facilitates tumor metastasis via the mTOR/p70S6K signaling pathway in pancreatic cancer
    Chenlei Zheng, Tan Zhang, Ding Li, Chongchu Huang, Hengjie Tang, Xiaofeng Ni, Bicheng Chen · 2020 · Oncology Reports
  32. Ribosomal S6 kinase 1 regulates ‘inflammaging’ via the senescence secretome
    Gallage, Suchira, Irvine, Elaine E., Pedroni, Silvia M.A., Barragan Avila, Jose Efren, Khadayate, Sanjay, Pombo, Joaquim, Brookes, Sharon, Heide, Danijela, Dharmalingham, Gopuraja, Choudhury, Agharul I. et al. · 2023
  33. S6 Kinase Inhibits Intrinsic Axon Regeneration Capacity via AMP Kinase inCaenorhabditis elegans
    Thomas Hubert, Zilu Wu, Andrew D. Chisholm, Yishi Jin · 2014 · Journal of Neuroscience
  34. Alcohol Intoxication Following Muscle Contraction in Mice Decreases Muscle Protein Synthesis But Not mTOR Signal Transduction
    Jennifer L. Steiner, Charles H. Lang · 2015 · Alcoholism Clinical and Experimental Research
  35. Role of translation initiation factor 4G in lifespan regulation and age-related health
    Amber C. Howard, Aric N. Rogers · 2014 · Ageing Research Reviews
  36. RETRACTED: Genetically reducing mTOR signaling rescues central insulin dysregulation in a mouse model of Alzheimer's disease
    Antonella Caccamo, Ramona Belfiore, Salvatore Oddo · 2018 · Neurobiology of Aging · Retracted
  37. Abrogating GPT2 in triple‐negative breast cancer inhibits tumor growth and promotes autophagy
    Devina Mitra, Silvia Vega-Rubín-de-Celis, Nadine Royla, Stephan Bernhardt, Heike Wilhelm, Nooraldeen Tarade, Gernot Poschet, Michael Buettner, Ilona Binenbaum, Simone Borgoni et al. · 2020 · International Journal of Cancer
  38. mTOR signaling: A pivotal player in Treg cell dysfunction in systemic lupus erythematosus
    Xingyun Zhao, Shifen Wang, Shengjun Wang, Jue Xie, Dawei Cui · 2022 · Clinical Immunology
  39. Erythroid induction of K562 cells treated with mithramycin is associated with inhibition of raptor gene transcription and mammalian target of rapamycin complex 1 (mTORC1) functions
    Alessia Finotti, Nicoletta Bianchi, Enrica Fabbri, Monica Borgatti, Giulia Breveglieri, Jessica Gasparello, Roberto Gambari · 2014 · Pharmacological Research
  40. Overexpression of RPS6KB1 predicts worse prognosis in primary HCC patients
    Pin Dong Li, Wen Jie Zhang, Mei Ying Zhang, Lin Jing Yuan, Yin Lian, Xiao Fang Ying, Gang Wu, Hui Wang · 2012 · Medical Oncology
  41. Silencing AXL by covalent siRNA-gelatin-antibody nanoconjugate inactivates mTOR/EMT pathway and stimulates p53 for TKI sensitization in NSCLC
    Dhananjay Suresh, Ajit P. Zambre, S. Mukherjee, Shreya Ghoshdastidar, Yuexu Jiang, Trupti Joshi, Anandhi Upendran, Raghuraman Kannan · 2019 · Nanomedicine Nanotechnology Biology and Medicine
  42. Ribosomal S6 kinase 1 regulates inflammaging via the senescence secretome
    2024
  43. Intermittent fasting and neurodegenerative diseases: Molecular mechanisms and therapeutic potential
    Renjun Lv, Bin Liu, Ziying Jiang, Runfa Zhou, Xiaoxing Liu, Tangsheng Lu, Yanping Bao, Chunxia Huang, Guichang Zou, Zongyong Zhang et al. · 2024 · Metabolism
  44. Gossypol sensitizes the antitumor activity of 5-FU through down-regulation of thymidylate synthase in human colon carcinoma cells
    Dan Yang, Jinglei Qu, Xiujuan Qu, Yubo Cao, Ling Xu, Kezuo Hou, Wanyu Feng, Yunpeng Liu · 2015 · Cancer Chemotherapy and Pharmacology
  45. Apoptotic Cells Activate AMP-activated Protein Kinase (AMPK) and Inhibit Epithelial Cell Growth without Change in Intracellular Energy Stores
    Vimal A. Patel, Donald Massenburg, Snezana Vujicic, Lanfei Feng, Meiyi Tang, Natalia O. Litbarg, Angelika Antoni, Joyce Rauch, Wilfred Lieberthal, Jerrold S. Levine · 2015 · Journal of Biological Chemistry
  46. Mutation of the 3-Phosphoinositide-Dependent Protein Kinase 1 (PDK1) Substrate-Docking Site in the Developing Brain Causes Microcephaly with Abnormal Brain Morphogenesis Independently of Akt, Leading to Impaired Cognition and Disruptive Behaviors
    Lluís Cordón-Barris, Sònia Pascual-Guiral, Shaobin Yang, Lydia Giménez‐Llort, Silvia Lope‐Piedrafita, Carlota Niemeyer, Enrique Claro, José Miguel Lizcano, José Ramón Bayascas · 2016 · Molecular and Cellular Biology
  47. Heat induces myogenic transcription factors of myoblast cells via transient receptor potential vanilloid 1 (Trpv1)
    Syotaro Obi, Toshiaki Nakajima, Takaaki Hasegawa, Fumitaka Nakamura, Masashi Sakuma, Shigeru Toyoda, Chuwa Tei, Teruo Inoue · 2018 · FEBS Open Bio
  48. mTORC1/AMPK responses define a core gene set for developmental cell fate switching
    Pundrik Jaiswal, Alan R. Kimmel · 2019 · BMC Biology
  49. Imaging and Editing the Phospholipidome
    Din-Chi Chiu, Jeremy M. Baskin · 2022 · Accounts of Chemical Research
  50. Metabolic disorders sensitise endometrial carcinoma through endoplasmic reticulum stress
    Jingyi Zhou, Yanying Lin, Xiao Yang, Boqiang Shen, Juan Hao, Jiaqi Wang, Jianliu Wang · 2022 · Cellular & Molecular Biology Letters
  51. Compensation of the AKT signaling by ERK signaling in transgenic mice hearts overexpressing TRIM72
    Young‐Mi Ham, Sarah J. Mahoney · 2013 · Experimental Cell Research
  52. Activation of the mTORC1 and STAT3 pathways promotes the malignant transformation of colitis in mice
    Zhen He, Xiaosheng He, Zexian Chen, Jia Ke, Xiaowen He, Ruixue Yuan, Zerong Cai, XIUTING CHEN, Xiaojian Wu, Ping Lan · 2014 · Oncology Reports
  53. Loquat leaf extract enhances myogenic differentiation, improves muscle function and attenuates muscle loss in aged rats
    Bokyung Sung, Seong Yeon Hwang, Min Jo Kim, Minjung Kim, Ji Won Jeong, Cheol Min Kim, Hae Young Chung, Nam Deuk Kim · 2015 · International Journal of Molecular Medicine
  54. Hyperglycemia-induced changes in miRNA expression patterns in epicardial adipose tissue of piglets
    Ewa Anna Oclon, Anna Latacz, Joanna Zubel–Łojek, K Pierzchała · 2016 · Journal of Endocrinology
  55. Autophagy-lysosomal defect in human CADASIL vascular smooth muscle cells
    Evelyn S. Hanemaaijer, Mahmod Panahi, Nol Swaddiwudhipong, Saara Tikka, Bengt G. Winblad, Matti H. Viitanen, Antonio Piras, Homira Behbahani · 2018 · European Journal of Cell Biology
  56. Towards Kinase Inhibitor Therapies for Fragile X Syndrome: Tweaking Twists in the Autism Spectrum Kinase Signaling Network
    D’Incal, Claudio, Broos, Jitse, Torfs, Thierry, Kooy, R. Frank, Vanden Berghe, Wim · 2022 · Cells
  57. RIPK1 senses S-adenosylmethionine scarcity to drive cell death and inflammation
    Zezhao Chen, Xiaosong Gu, Hongbo Chen, Huijing Zhang, Jianping Liu, Xiaohua Yang, Yuping A. Cai, Mengmeng Zhang, Lingjie Yan, Yuanxin Yang et al. · 2025 · Cell Metabolism
  58. PERK Signal-Modulated Protein Translation Promotes the Survivability of Dengue 2 Virus-Infected Mosquito Cells and Extends Viral Replication
    Jiun-Nan Hou, Tien-Huang Chen, Yi‐Hsuan Chiang, Jing‐Yun Peng, Tsong-Han Yang, Chih-Chieh Cheng, Eny Sofiyatun, Cheng‐Hsun Chiu, Chuan Chiang-Ni, Wei‐June Chen · 2017 · Viruses
  59. Phosphoserine Phosphatase Promotes Lung Cancer Progression through the Dephosphorylation of IRS-1 and a Noncanonical L-Serine-Independent Pathway.
    Seongmin Park, Eun-Hye Seo, Dong-Hyuck Bae, Sung Soo Kim, Jina Kim, Weiwei Lin, Kyung‐Hee Kim, Jong Bae Park, Seon‐Young Kim, Jinlong Yin et al. · 2019 · PubMed Central
  60. Are Glucosylceramide-Related Sphingolipids Involved in the Increased Risk for Cancer in Gaucher Disease Patients? Review and Hypotheses
    Patricia Dubot, Leonardo M. Astudillo, Nicole Therville, Frédérique Sabourdy, Jérôme Stirnemann, Thierry Levade, Nathalie Andrieu‐Abadie · 2020 · Cancers
  61. Fibroblast growth factor 21 and autophagy: A complex interplay in Parkinson disease
    Violina Kakoty, K C Sarathlal, Ruei-Dun Tang, Chih Hao Yang, Sunil Kumar Dubey, Rajeev Taliyan · 2020 · Biomedicine & Pharmacotherapy
  62. 4-(Difluoromethyl)-5-(4-((3 R ,5 S )-3,5-dimethylmorpholino)-6-(( R )-3-methylmorpholino)-1,3,5-triazin-2-yl)pyridin-2-amine (PQR626), a Potent, Orally Available, and Brain-Penetrant mTOR Inhibitor for the Treatment of Neurological Disorders
    Chiara Borsari, Erhan Keleş, Denise Rageot, Andrea Treyer, Thomas Bohnacker, Lukas Bissegger, Martina De Pascale, Anna Melone, Rohitha Sriramaratnam, Florent Beaufils et al. · 2020 · Journal of Medicinal Chemistry
  63. Regulation of mTORC1 activity by the Golgi apparatus
    Christian Makhoul, Paul A. Gleeson · 2021 · Faculty Reviews
  64. TOR signaling regulates liquid phase separation of the SMN complex governing snRNP biogenesis
    Maximilian Schilling, Archana Bairavasundaram Prusty, Bjorn M. M. Boysen, Felix S. Oppermann, Yannick L. Riedel, Alma Husedzinovic, Homa Rasouli, Angelika König, Pradhipa Ramanathan, Jürgen Reymann et al. · 2021 · Cell Reports
  65. Dissecting the biology of mTORC1 beyond rapamycin
    Guang Yang, Deanne Francis, James Robert Krycer, Mark Larance, Ziyang Zhang, Chris J. Novotny, Alexis Díaz‐Vegas, Kevan M. Shokat, David Ernest James · 2021 · Science Signaling
  66. Differential Requirement of the Ribosomal Protein S6 and Ribosomal Protein S6 Kinase for Plant-Virus Accumulation and Interaction of S6 Kinase with Potyviral VPg
    Minna‐Liisa Rajamäki, Dehui Xi, Sidona Sikorskaitė-Gudžiūnienė, Jari P. T. Valkonen, Steven A. Whitham · 2017 · Molecular Plant-Microbe Interactions
  67. Premature recruitment of oocyte pool and increased mTOR activity in Fmr1 knockout mice and reversal of phenotype with rapamycin
    Evelyn Y. Mok-Lin, Manuel Ascano, Artem A. Serganov, Zev Rosenwaks, Thomas Tuschl, Zev Williams · 2018 · Scientific Reports
  68. Inhibition of interleukin 8/C‑X-C chemokine receptor�1,/2 signaling reduces malignant features in human pancreatic cancer cells
    Shengling Fu, Xiang 'Anthony' Chen, Huey-Jen L. Lin, Jiayuh Lin · 2018 · International Journal of Oncology
  69. A leucine-rich diet modulates the mTOR cell signalling pathway in the gastrocnemius muscle under different Walker-256 tumour growth conditions
    Bread Cruz, André Gustavo de Oliveira, Gislaine Ventrucci, Maria Cristina Cintra Gomes‐Marcondes · 2019 · BMC Cancer
  70. Cross Talk Networks of Mammalian Target of Rapamycin Signaling With the Ubiquitin Proteasome System and Their Clinical Implications in Multiple Myeloma
    Ruth Eichner, Vanesa Fernández‐Sáiz, Bianca‐Sabrina Targosz, Florian C. Bassermann · 2018 · International review of cytology
  71. Dietary AGEs involvement in colonic inflammation and cancer: insights from an in vitro enterocyte model
    Ovidiu Ionuț Geicu, Loredana Stanca, Sorina Nicoleta Voicu, Anca Dinischiotu, Liviu Bîlteanu, Andreea Iren Șerban, Valentin Calu · 2020 · Scientific Reports
  72. Comprehensive analysis of the ubiquitinome during oncogene-induced senescence in human fibroblasts
    Fee Bengsch, Zhigang Tu, Hsin‐Yao Tang, Hengrui Zhu, David W. Speicher, Rugang Zhang · 2015 · Cell Cycle
  73. Axonal protein synthesis and the regulation of primary afferent function
    Ilona Obara, Stephen P. Hunt · 2013 · Developmental Neurobiology
  74. Cyclin-dependent Kinase 5 (Cdk5)-dependent Phosphorylation of p70 Ribosomal S6 Kinase 1 (S6K) Is Required for Dendritic Spine Morphogenesis
    Kwok‐On Lai, Zhuoyi Liang, Erkang Fei, Huiqian Huang, Nancy Y. Ip · 2015 · Journal of Biological Chemistry
  75. Glycolysis in Panc-1 human pancreatic cancer cells is inhibited by everolimus
    Ling Liu, Liansheng Gong, YANGDE ZHANG, NIANFENG LI · 2012 · Experimental and Therapeutic Medicine
  76. Mathematical Modelling of Metabolic Regulation in Aging
    Mark T. Mc Auley, Kathleen Mooney, Peter J. Angell, Stephen J. Wilkinson · 2015 · Metabolites
  77. Targeting the Mammalian Target of Rapamycin in Lung Cancer
    Glenn W. Vicary, Jesse Roman · 2016 · The American Journal of the Medical Sciences
  78. Fenofibrate inhibits mTOR-p70S6K signaling and simultaneously induces cell death in human prostate cancer cells
    Xin Lian, Junlian Gu, Baoshan Gao, Yan Li, Chendil Damodaran, Wei Wei, Yaowen Fu, Lu Cai · 2018 · Biochemical and Biophysical Research Communications
  79. Lessons from animal nutritionists: dietary amino acid requirement studies and considerations for healthy aging studies
    Anna Kate K Shoveller, Leslie L. McKnight, Katharine M Wood, John P. Cant · 2018 · Annals of the New York Academy of Sciences
  80. The dual PI3K/mTOR inhibitor NVP-BEZ235 inhibits proliferation and induces apoptosis of burkitt lymphoma cells
    Chuntuan Li, Pengliang Xin, Huifang Xiao, Yan Zheng, Yuanling Huang, Xiongpeng Zhu · 2015 · Cancer Cell International
  81. Phosphorylation of Ser6 in hnRNPA1 by S6K2 regulates glucose metabolism and cell growth in colorectal cancer
    Yan Sun, Man Luo, Guilin Chang, Weiying Ren, Kefen Wu, Xi Li, Jiping Shen, Xiaoping Zhao, Yu Hu · 2017 · Oncology Letters
  82. Aberrant modulation of ribosomal protein S6 phosphorylation confers acquired resistance to MAPK pathway inhibitors in BRAF-mutant melanoma
    Mingzhao Gao, Hongbin Wang, Xiangling Chen, Wen-ting Cao, Fu Li, Yun Li, Haitian Quan, Chengying Xie, Liguang Lou · 2018 · Acta Pharmacologica Sinica
  83. The GATOR complex regulates an essential response to meiotic double-stranded breaks in Drosophila
    You-Heng Wei, L. Bettedi, Chun-Yuan Ting, Kuikwon Kim, Ying-Biao Zhang, Jia-Dong Cai, M. Lilly · 2018 · bioRxiv
  84. Prosurvival IL-7–Stimulated Weak Strength of mTORC1-S6K Controls T Cell Memory via Transcriptional FOXO1–TCF1–Id3 and Metabolic AMPKα1–ULK1–ATG7 Pathways
    Aizhang Xu, Scot C. Leary, Md. Fahmid Islam, Zhaojia Wu, Kalpana Kalyanasundaram Bhanumathy, Anjuman Ara, Rajni Chibbar, Andrew Fleywald, Khawaja Ashfaque Ahmed, Jim Xiang · 2021 · The Journal of Immunology
  85. eIF3a regulation of mTOR signaling and translational control via HuR in cellular response to DNA damage
    Shijie Ma, Zizheng Dong, Yanfei Huang, Jingyuan Liu, Jian‐Ting Zhang · 2022 · Oncogene
  86. Insulin Signaling in Insulin Resistance States and Cancer: A Modeling Analysis
    ALESSANDRO BERTUZZI, Federica Conte, Geltrude Mingrone, Federico Papa, Serenella Salinari, Carmela Sinisgalli · 2016 · PLoS ONE
  87. Muscle-specific deletion of BDK amplifies loss of myofibrillar protein during protein undernutrition
    Takuya Ishikawa, Yasuyuki Kitaura, Yoshihiro Kadota, Yukako Morishita, Miki Ota, Fumiya Yamanaka, Minjun Xu, Masahito Ikawa, Naokazu Inoue, Fuminori Kawano et al. · 2017 · Scientific Reports
  88. C. elegans DAF-16/FOXO interacts with TGF-ß/BMP signaling to induce germline tumor formation via mTORC1 activation
    Wenjing Qi, Yijian Yan, Dietmar Pfeifer, Erika Donner von Gromoff, Yimin Wang, Wolfgang Maier, Ralf Baumeister · 2017 · PLoS Genetics
  89. Comparative transcriptome analysis of the Pacific White Shrimp (Litopenaeus vannamei) muscle reveals the molecular basis of residual feed intake
    Ping Dai, Sheng Luan, Xia Lu, Kun Luo, Jie Kong · 2017 · Scientific Reports
  90. A rapamycin derivative, biolimus, preferentially activates autophagy in vascular smooth muscle cells
    Yerin Kim, Jun‐Kyu Park, Jun‐Hyuk Seo, Hyun-Seung Ryu, Kyung Seob Lim, Myung Ho Jeong, Dong Hoon Kang, Sang Won Kang · 2018 · Scientific Reports
  91. Mesenchymal stem cells of Systemic Sclerosis patients, derived from different sources, show a profibrotic microRNA profiling
    Paola Di Benedetto, Noemi Panzera, Paola Cipriani, Valentina Mastroiaco, Alessandra Tessitore, Vasiliki Liakouli, Piero Ruscitti, Onorina Berardicurti, Francesco Carubbi, Giuliana Guggino et al. · 2019 · Scientific Reports
  92. Signaling pathways activated by the B-cell receptor in chronic lymphocytic leukemia
    Maria Teresa Scupoli, Giovanni Pizzolo · 2012 · Expert Review of Hematology
  93. Lrp5 Has a Wnt-Independent Role in Glucose Uptake and Growth for Mammary Epithelial Cells
    Emily N. Chin, Joshua A. Martin, So Young Kim, Saja A. Fakhraldeen, Caroline M. Alexander · 2015 · Molecular and Cellular Biology
  94. Sepsis Attenuates the Anabolic Response to Skeletal Muscle Contraction
    Jennifer L. Steiner, Charles H. Lang · 2014 · Shock
  95. Acarbose improved survival for Apc+/Min mice
    Sherry G. Dodds, Manish Parihar, Martin A. Javors, Jia Nie, Nicolas Musi, Zelton Dave Sharp, Paul Hasty · 2020 · Aging Cell
  96. Metformin impairs cisplatin resistance effects in A549 lung cancer cells through mTOR signaling and other metabolic pathways
    Ana Paula Morelli, Tharcísio Citrângulo Tortelli, Isadora Carolina Betim Pavan, Fernando Riback Silva, Daniela C. Granato, Guilherme Francisco Peruca, Bianca Alves Pauletti, Romênia R. Domingues, Rosângela Maria Neves Bezerra, Leandro Pereira de Moura et al. · 2021 · International Journal of Oncology
  97. Cited2 Is Required for the Maintenance of Glycolytic Metabolism in Adult Hematopoietic Stem Cells
    Jinwei Du, Qiang Li, Fangqiang Tang, Michelle Puchowitz, Hisashi Fujioka, Sally L. Dunwoodie, David Danielpour, Yu‐Chung Yang · 2013 · Stem Cells and Development
  98. Identification of the general transcription factor Yin Yang 1 as a novel and specific binding partner for S6 Kinase 2
    Heba M. Ismail, Olena Myronova, Yugo Tsuchiya, Andrew Niewiarowski, Irina R. Tsaneva, Ivan T. Gout · 2013 · Cellular Signalling
  99. Reproductive state-dependent plasticity in the visual system of an African cichlid fish
    Julie M. Butler, Sarah M. Whitlow, Loranzie S. Rogers, Rosalyn L. Putland, Allen F. Mensinger, Karen P. Maruska · 2019 · Hormones and Behavior
  100. MEK1/2 Overactivation Can Promote Growth Arrest by Mediating ERK1/2-Dependent Phosphorylation of p70S6K
    Jean‐Philippe Guégan, Frédéric Ezan, Luc Gailhouste, Sophie Langouët, Georges Baffet · 2013 · Journal of Cellular Physiology