Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networks
Magnuson, Brian, Ekim, Bilgen, Fingar, Diane C.·2012·Biochemical Journal
Cited by (1,000)
Items 201–300 of 1,000
- Contemporary mTOR inhibitor scaffolds to diseases breakdown: A patent review (2015–2021)Patrik Olekšák, Eugenie Nepovimová, Žofia Chrienová, Kamil Musílek, Jiří Patočka, Kamil Kuča · 2022 · European Journal of Medicinal Chemistry
- Regulation of actin dynamics and protein trafficking during spermatogenesis – Insights into a complex processWenhui Su, Dolores D. Mruk, C. Yan Cheng · 2013 · Critical Reviews in Biochemistry and Molecular Biology
- Exercise type and volume alter signaling pathways regulating skeletal muscle glucose uptake and protein synthesisJuha P. Ahtiainen, Simon Walker, Mika Silvennoinen, Heikki Kyröläinen, Bradley Charles Nindl, Keijo Häkkinen, Kai Nyman, Harri Selänne, Juha J. Hulmi · 2015 · European Journal of Applied Physiology
- Host mTORC1 Signaling Regulates Andes Virus ReplicationShannon McNulty, Mike Flint, Stuart T. Nichol, Christina F. Spiropoulou · 2012 · Journal of Virology
- S6Ks isoforms contribute to viability, migration, docetaxel resistance and tumor formation of prostate cancer cellsCamila Libardi do Amaral, Lidia Freitas, Rodrigo Esaki Tamura, Mariana Rosolen Tavares, Isadora Carolina Betim Pavan, Marcio Chaim Bajgelman, Fernando Moreira Simabuco · 2016 · BMC Cancer
- IGF1 stimulates greater muscle hypertrophy in the absence of myostatin in male miceAlex Hennebry, Jenny M. Oldham, Tea Shavlakadze, Miranda D. Grounds, Philip W. Sheard, Marta L. Fiorotto, Shelley J. Falconer, Heather K. Smith, Carole Berry, Ferenc Jeanplong et al. · 2017 · Journal of Endocrinology
- N-Terminal Proteoforms in Human Disease.A. Bogaert, E. Fernandez, K. Gevaert · 2020 · TIBS -Trends in Biochemical Sciences. Regular ed
- Hyperactivation of TORC1 drives resistance to the pan-HER tyrosine kinase inhibitor neratinib in HER2-mutant cancersSudhan, Dhivya R., Guerrero-Zotano, Angel, Won, Helen, González Ericsson, Paula, Servetto, Alberto, Huerta-Rosario, Mariela, Ye, Dan, Lee, Kyung-min, Formisano, Luigi, Guo, Yan et al. · 2020 · Cancer Cell
- Effect of dietary replacement of fish meal with low-gossypol cottonseed protein concentrate on growth performance and expressions of genes related to protein metabolism for swimming crab (Portunus trituberculatus)Shichao Xie, Qicun Zhou, Xiangsheng Zhang, Tingting Zhu, Chen Guo, Zheng Yang, Jiaxiang Luo, Ye Yuan, Xiaoyin Hu, Lefei Jiao et al. · 2021 · Aquaculture
- The Importance of mTOR Trafficking for Human Skeletal Muscle Translational ControlNathan W. Hodson, Andrew Philp · 2018 · Exercise and Sport Sciences Reviews
- Protein kinase inhibitors for amyotrophic lateral sclerosis therapyValle Palomo, Vanesa Nozal, Elisa Rojas‐Prats, Carmen Gil, Ana Martı́nez · 2020 · British Journal of Pharmacology
- Gender‐specific differences in the development of sarcopenia in the rodent model of the ageing high‐fat ratKob, Robert, Fellner, Claudia, Bertsch, Thomas, Wittmann, Astrid, Mishura, Daria, Sieber, Cornel C., Fischer, Barbara E., Stroszczynski, Christian, Bollheimer, Cornelius L. · 2015 · Journal of Cachexia, Sarcopenia and Muscle
- Discovery of human cell selective effector molecules using single cell multiplexed activity metabolomicsEarl, David C., Ferrell, P. Brent, Leelatian, Nalin, Froese, Jordan T., Reisman, Benjamin J., Irish, Jonathan M., Bachmann, Brian O. · 2018 · Nature Communications
- Identification of MicroRNAs Differentially Expressed in Lung Carcinoid Subtypes and ProgressionIda Rapa, Arianna Votta, Barbara Felice, Luisella Righi, Jessica Giorcelli, Aldo Scarpa, Ernst‐Jan M. Speel, Giorgio V. Scagliotti, Mauro Giulio Papotti, Marco Volante · 2015 · Neuroendocrinology
- Rapamycin Loaded Solid Lipid Nanoparticles as a New Tool to Deliver mTOR Inhibitors: Formulation and in Vitro CharacterizationAlice Polchi, Alessandro Magini, Jarosław Mazuryk, Brunella Tancini, Jacek Gapiński, A. Patkowski, Stefano Giovagnoli, Carla Emiliani · 2016 · Nanomaterials
- Neural and behavioural correlates of repeated social defeatJulie M. Butler, Sarah M. Whitlow, David A. Roberts, Karen P. Maruska · 2018 · Scientific Reports
- Cancer cachexia: molecular basis and therapeutic advancesYuting Tan, Rui Xue, Yuwei Pan, zongsheng he, Xiao Hu, Yaping Li, Ke Li, Xuan Zhang, Xiu-wu Bian, Bin Wang · 2026 · Signal Transduction and Targeted Therapy
- The role of adiponectin signaling in metabolic syndrome and cancerMichael P. Scheid, Gary Sweeney · 2013 · Reviews in Endocrine and Metabolic Disorders
- Rheb (Ras Homologue Enriched in Brain)-dependent Mammalian Target of Rapamycin Complex 1 (mTORC1) Activation Becomes Indispensable for Cardiac Hypertrophic Growth after Early Postnatal PeriodTakahito Tamai, Osamu Yamaguchi, Shungo Hikoso, Toshihiro Takeda, Manabu Taneike, Takafumi Oka, Jota Oyabu, Tomokazu Murakawa, Hiroyuki Nakayama, Yoshihiro Uno et al. · 2013 · Journal of Biological Chemistry
- MRF Family Genes Are Involved in Translation Control, Especially under Energy-Deficient Conditions, and Their Expression and Functions Are Modulated by the TOR Signaling PathwayDu‐Hwa Lee, Seung Jun Park, Chang Sook Ahn, Hyun‐Sook Pai · 2017 · The Plant Cell
- Multisite Phosphorylation of S6K1 Directs a Kinase Phospho-code that Determines Substrate SelectionAbul Arif, Jie Jia, Belinda B. Willard, Xiaoxia Li, Paul L. Fox · 2019 · Molecular Cell
- A Conformational Restriction Strategy for the Identification of a Highly Selective Pyrimido-pyrrolo-oxazine mTOR InhibitorChiara Borsari, Denise Rageot, Alix Dall’Asen, Thomas Bohnacker, Anna Melone, Alexander Sele, Eileen Jackson, Jean-Baptiste Langlois, Florent Beaufils, Paul Hebeisen et al. · 2019 · Journal of Medicinal Chemistry
- RUNX1/RUNX1T1 mediates alternative splicing and reorganises the transcriptional landscape in leukemiaVasily V. Grinev, Farnaz Barneh, Ilya M. Ilyushonak, Sirintra Nakjang, Job Smink, Anita van Oort, Richard Clough, Michael Seyani, Hesta V. McNeill, Mojgan Reza et al. · 2021 · Nature Communications
- NPM-ALK: The Prototypic Member of a Family of Oncogenic Fusion Tyrosine KinasesJoel D. Pearson, Jason K. H. Lee, Julinor T. C. Bacani, Raymond L. Lai, Robert J. Ingham · 2012 · Journal of Signal Transduction
- p70S6K promotes IL-6-induced epithelial-mesenchymal transition and metastasis of head and neck squamous cell carcinomaDandan Wu, Jie Cheng, Geng Sun, Shengjie Wu, Min Li, Zhongyuan Gao, Sulan Zhai, Ping Li, Dongming Su, Xuerong Wang · 2016 · Oncotarget
- “Immune TOR-opathies,” a Novel Disease Entity in Clinical ImmunologySophie Jung, Laura Y. Gámez-Díaz, Michele Proietti, Bodo Grimbacher · 2018 · Frontiers in Immunology
- Leucine does not affect mechanistic target of rapamycin complex 1 assembly but is required for maximal ribosomal protein s6 kinase 1 activity in human skeletal muscle following resistance exerciseApró, William, Moberg, Marcus, Hamilton, D. Lee, Ekblom, Björn, Rooyackers, Olav, Holmberg, Hans‐Christer, Blomstrand, Eva · 2015 · The FASEB Journal
- Mutations in Critical Domains Confer the Human mTOR Gene Strong Tumorigenicity*Avaniyapuram Kannan Murugan, Ali Saeed Alzahrani, Mingzhao Xing · 2013 · Journal of Biological Chemistry
- eIF4EBP3L Acts as a Gatekeeper of TORC1 In Activity-Dependent Muscle Growth by Specifically Regulating Mef2ca Translational InitiationOrli Yogev, Victoria C. Williams, Yaniv Hinits, Simon M. Hughes · 2013 · PLoS Biology
- Influence of miR-155 on Cell Apoptosis in Rats with Ischemic Stroke: Role of the Ras Homolog Enriched in Brain (Rheb)/mTOR PathwayGuoping Xing, Zengxiang Luo, Chi Zhong, Xudong Pan, Xiaowei Xu · 2016 · Medical Science Monitor
- mTOR Suppresses Macroautophagy During Striatal Postnatal Development and Is Hyperactive in Mouse Models of Autism Spectrum DisordersOri J. Lieberman, Veronica Cartocci, Irena Pigulevskiy, Maya Molinari, Josep Carbonell, Miguel Bellés Broseta, Michael R. Post, David Sulzer, Anders Borgkvist, Emanuela Santini · 2020 · Frontiers in Cellular Neuroscience
- Therapies modulating insulin resistance in Parkinson’s disease: A cross talkSharma, Tanya, Kaur, Darshpreet, Grewal, Amarjot Kaur, Singh, Thakur Gurjeet · 2021 · Neuroscience Letters
- Evaluation of EGFR and RTK Signaling in the Electrotaxis of Lung Adenocarcinoma Cells under Direct-Current Electric Field StimulationHsieh‐Fu Tsai, Ching-Wen Huang, Hui‐Fang Chang, Jeremy J.W. Chen, Chau‐Hwang Lee, Ji‐Yen Cheng · 2013 · PLoS ONE
- Emerging Role of Non-Coding RNAs in Regulation of T-Lymphocyte FunctionMohammad Naser Taheri, Dominik Andreas Barth, Julia Kargl, Omidvar Rezaei, Soudeh Ghafouri‐Fard, Martin Pichler · 2021 · Frontiers in Immunology
- Intracellular Carbonic Anhydrase Activity Sensitizes Cancer Cell pH Signaling to Dynamic Changes in CO2 Partial PressureAlžbeta Hulı́ková, Nicholas Aveyard, Adrian Llewellyn Harris, Richard D. Vaughan‐Jones, Pawel Swietach · 2014 · Journal of Biological Chemistry
- Essential amino acid infusions stimulate mammary expression of eukaryotic initiation factor 2Bε but milk protein yield is not increased during an imbalanceJohn Doelman, R.V. Curtis, Michelle Carson, J.J.M. Kim, John A. Metcalf, John P. Cant · 2015 · Journal of Dairy Science
- p70S6K1 in the TORC1 pathway is essential for the differentiation of Th17 Cells, but not Th1, Th2, or Treg cells in miceCarl Y. Sasaki, Gang Chen, Rachel B. Munk, Erez Eitan, Jennifer L. Martindale, Dan L. Longo, Paritosh Ghosh · 2015 · European Journal of Immunology
- Mis-regulation of Mammalian Target of Rapamycin (mTOR) Complexes Induced by Albuminuria in Proximal TubulesDiogo B. Peruchetti, Jie Cheng, Celso Caruso‐Neves, William B. Guggino · 2014 · Journal of Biological Chemistry
- Inositol Hexaphosphate Inhibits Proliferation and Induces Apoptosis of Colon Cancer Cells by Suppressing the AKT/mTOR Signaling PathwayMałgorzata Kapral, Joanna Wawszczyk, Katarzyna Jesse, Monika Paul-Samojedny, Dariusz Kuśmierz, Ludmiła Węglarz · 2017 · Molecules
- Targeting mTOR with MLN0128 Overcomes Rapamycin and Chemoresistant Primary Effusion LymphomaCarolina Caro‐Vegas, Aubrey Bailey, Riccardo Bigi, Blossom Damania, Dirk P. Dittmer · 2019 · mBio
- The structural and functional workings of KEOPSJonah Beenstock, Frank Sicheri · 2021 · Nucleic Acids Research
- Exploring the mTOR Signalling Pathway and Its Inhibitory Scope in CancerSuhail Ahmad Mir, Ashraf Dar, Saad Ali Alshehri, Shadma Wahab, Laraibah Hamid, Mohammad Ali Abdullah Almoyad, Tabasum Ali, Ghulam Nabi Bader · 2023 · Pharmaceuticals
- Prolonged Calorie Restriction Downregulates Skeletal Muscle mTORC1 Signaling Independent of Dietary Protein Intake and Associated microRNA ExpressionLee M. Margolis, Donato Americo Rivas, Maria Berrone, Yassine Ezzyat, Andrew Young, James P. McClung, Roger A. Fielding, Stefan M. Pasiakos · 2016 · Frontiers in Physiology
- S6K1 phosphorylation-dependent degradation of Mxi1 by β-Trcp ubiquitin ligase promotes Myc activation and radioresistance in lung cancerYumei Huang, Kaishun Hu, Sheng Zhang, Xiaorong Dong, Zhongyuan Yin, Rui Meng, Yingchao Zhao, Xiaofang Dai, Tao Zhang, Kunyu Yang et al. · 2018 · Theranostics
- Src Family Kinase Inhibitors Block Translation of Alphavirus Subgenomic mRNAsRebecca M. Broeckel, Sanjay Sarkar, Nicholas A. May, Jennifer E. Totonchy, Craig N. Kreklywich, Patricia P. Smith, Lee M. Graves, Victor R. DeFilippis, Mark T. Heise, Thomas E. Morrison et al. · 2019 · Antimicrobial Agents and Chemotherapy
- Predicting Causal Relationships from Biological Data: Applying Automated Causal Discovery on Mass Cytometry Data of Human Immune CellsSofia Triantafillou, Vincenzo Lagani, Christina Heinze‐Deml, Angelika Schmidt, Jesper N. Tegner, Ioannis Tsamardinos · 2017 · Scientific Reports
- Beyond Genetics: The Role of Metabolism in Photoreceptor Survival, Development and RepairJoseph Hanna, Luke Ajay David, Yacine Touahri, Taylor Fleming, Robert A. Screaton, Carol Schuurmans · 2022 · Frontiers in Cell and Developmental Biology
- GSK3β Regulates Milk Synthesis in and Proliferation of Dairy Cow Mammary Epithelial Cells via the mTOR/S6K1 Signaling PathwayXia Zhang, Feng Zhao, Yu Si, Yu‐Ling Huang, Cuiping Yu, Chaochao Luo, Na Zhang, Qingzhang Li, Xuejun Gao · 2014 · Molecules
- TORC2 and the AGC kinase Gad8 regulate phosphorylation of the ribosomal protein S6 in fission yeastWei Du, Lenka Hálová, Sara Kirkham, Jane Atkin, Janni Petersen · 2012 · Biology Open
- GSK-3 directly regulates phospho-4EBP1 in renal cell carcinoma cell-line: an intrinsic subcellular mechanism for resistance to mTORC1 inhibitionHiromi Ito, Osamu Ichiyanagi, Sei Naito, Vladimir N. Bilim, Yoshihiko Tomita, Tomoyuki Kato, Akira Nagaoka, Norihiko Tsuchiya · 2016 · BMC Cancer
- Regulation and Modulation of Human DNA Polymerase δ Activity and FunctionMarietta Lee, Xiaoxiao Wang, Sufang Zhang, Zhongtao Zhang, Ernest Lee · 2017 · Genes
- EIF4EBP1 Overexpression Is Associated with Poor Survival and Disease Progression in Patients with Hepatocellular CarcinomaYin-Lian Cha, Pin-Dong Li, Lin-Jing Yuan, Mei-Yin Zhang, Yaojun Zhang, Hui‐Lan Rao, Hui-Zhong Zhang, X.F. Steven Zheng, Hui-Yun Wang · 2015 · PLoS ONE
- Functional proteomics characterization of residual triple-negative breast cancer after standard neoadjuvant chemotherapyJoohyuk Sohn, K.A. Do, Shenting Liu, H. Chen, Gordon Brent Mills, Gabriel N. Hortobágyi, Funda Meric‐Bernstam, Ana Maria Gonzalez-Angulo · 2013 · Annals of Oncology
- Mammalian target of rapamycin complex (mTOR) pathway modulates blood-testis barrier (BTB) function through F-actin organization and gap junction.Li N, C. Yan Cheng · 2016 · PubMed
- Retracted: MicroRNA‐99b suppresses human cervical cancer cell activity by inhibiting the PI3K/AKT/mTOR signaling pathwayYong‐Jie Li, Yue Wang, Yi‐Ying Wang · 2018 · Journal of Cellular Physiology · Retracted
- Ribosomal Proteins Control Tumor Suppressor Pathways in Response to Nucleolar StressFrédéric Lessard, Léa Brakier‐Gingras, Gerardo Ferbeyre · 2019 · BioEssays
- Platelet-derived growth factor-induced Akt phosphorylation requires mTOR/Rictor and phospholipase C-γ1, whereas S6 phosphorylation depends on mTOR/Raptor and phospholipase DMasoud Razmara, Carl‐Henrik Heldin, Johan Lennartsson · 2013 · Cell Communication and Signaling
- Cellular pharmacodynamics of a novel
pyrrolo[3,2-d]pyrimidine inhibitor targeting mitochondrial and cytosolic
one-carbon metabolismDekhne, Aamod S., Ning, Changwen, Nayeen, Md. Junayed, Shah, Khushbu, Kalpage, Hasini, Frühauf, Josephine, Wallace-Povirk, Adrianne, O’Connor, Carrie, Hou, Zhanjun, Kim, Seongho et al. · 2020 · Molecular Pharmacology
- Metformin: An Inhibitor of mTORC1 SignalingBodo Clemens Melnik, Gerd Schmitz · 2014
- Complementary transcriptomic and proteomic analyses reveal regulatory mechanisms of milk protein production in dairy cows consuming different foragesWenting Dai, Qiong Chen, Quanjuan Wang, Robin R. White, Jianxin Liu, Hongyun Liu · 2017 · Scientific Reports
- Ribosomal proteins: insight into molecular roles and functions in hepatocellular carcinomaXiaozai Xie, Pan Guo, Hao Yu, Yanliang Wang, Gaojie Chen · 2017 · Oncogene
- Battling for Ribosomes: Translational Control at the Forefront of the Antiviral ResponseHuy‐Dung Hoang, Tyson Ernst Graber, Tommy Alain · 2018 · Journal of Molecular Biology
- Activating the translational repressor 4E-BP or reducing S6K-GSK3β activity prevents accelerated axon growth induced by hyperactive mTORin vivoXuan Gong, Longbo Zhang, Tianxiang Huang, Tiffany V. Lin, Laura C. Miyares, John H. Wen, Lawrence S. Hsieh, Angélique Bordey · 2015 · Human Molecular Genetics
- The isoprenoid perillyl alcohol inhibits telomerase activity in prostate cancer cellsTabetha Sundin, Dennis M. Peffley, David T. Gauthier, Patricia Hentosh · 2012 · Biochimie
- In search of antiaging modalities: Evaluation of mTOR‐ and ROS/DNA damage‐signaling by cytometryZbigniew Darżynkiewicz, Hong Zhao, H. Dorota Halicka, Jiangwei Li, Yong‐Syu Lee, Tze‐chen Hsieh, JOSEPH M. WU · 2014 · Cytometry Part A
- Dual blockage of STAT3 and ERK1/2 eliminates radioresistant GBM cellsBowen Xie, Lu Zhang, Wenfeng Hu, Ming Fan, Nian Jiang, Yumei Duan, Di Jing, Wenwu Xiao, Ruben C. Fragoso, Kit S. Lam et al. · 2019 · Redox Biology
- Survival strategies of cancer cells: the role of macropinocytosis in nutrient acquisition, metabolic reprogramming, and therapeutic targetingGuoshuai Xu, Qinghong Zhang, Renjia Cheng, Jun Qu, Wenqiang Li · 2025 · Autophagy
- PI3K/mTOR Signaling in Mesothelioma Patients Treated with Induction Chemotherapy Followed by Extrapleural PneumonectomyByron K.Y. Bitanihirwe, Mayura Meerang, Martina Friess, Alex Soltermann, Lukas Frischknecht, Svenja Thies, Emanuela Felley‐Bosco, Ming‐Sound Tsao, Ghassan Allo, Marc E. de Perrot et al. · 2014 · Journal of Thoracic Oncology
- Effects of dietary protein restriction on muscle fiber characteristics and mTORC1 pathway in the skeletal muscle of growing-finishing pigsYinghui Li, Fengna Li, Li Wu, Hongkui Wei, Yingying Liu, Tiejun Li, Bie Tan, Xiangfeng Kong, Yao Kang, Shuai Chen et al. · 2016 · Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology
- The LKB1‐AMPK and mTORC1 Metabolic Signaling Networks in Schwann Cells Control Axon Integrity and MyelinationBogdan Beirowski · 2018 · BioEssays
- TOR inhibitors: from mammalian outcomes to pharmacogenetics in plants and algaeMarie‐Hélène Montané, Benoît Menand · 2019 · Journal of Experimental Botany
- mTOR signaling in Brown and Beige adipocytes: implications for thermogenesis and obesityYuqing Ye, Hailan Liu, Feng Zhang, Fang Hu · 2019 · Nutrition & Metabolism
- The Roles of Post-Translational Modifications on mTOR SignalingShasha Yin, Liu Liu, Wenjian Gan · 2021 · International Journal of Molecular Sciences
- The space between notes: emerging roles for translationally silent ribosomesPatrick R. Smith, Sapna C. Pandit, Sarah Loerch, Zachary T. Campbell · 2022 · Trends in Biochemical Sciences
- Activation of the mTOR pathway by the amino acid l-leucine in the 5q- syndrome and other ribosomopathiesJacqueline Boultwood, Bon Ham Yip, Chaitanya Vuppusetty, Andrea Pellagatti, James S. Wainscoat · 2012 · Advances in Biological Regulation
- Elevated levels of p-Mnk1, p-eIF4E and p-p70S6K proteins are associated with tumor recurrence and poor prognosis in astrocytomasWeibing Fan, Weiyuan Wang, Xinfa Mao, Shuzhou Chu, Juan Feng, Desheng Xiao, Jianhua Zhou, Songqing Fan · 2016 · Journal of Neuro-Oncology
- Usnic Acid Benzylidene Analogues as Potent Mechanistic Target of Rapamycin Inhibitors for the Control of Breast MalignanciesHassan Y. Ebrahim, Mohamed R. Akl, Heba E. Elsayed, Ronald A. Hill, Khalid A. El Sayed · 2017 · Journal of Natural Products
- Fatal attraction: The roles of ribosomal proteins in the viral life cycleClare M. Miller, Sangeetha Selvam, Gabriele Fuchs · 2020 · Wiley Interdisciplinary Reviews - RNA
- Revealing Different Roles of the mTOR-Targets S6K1 and S6K2 in Breast Cancer by Expression Profiling and Structural AnalysisElin A. Karlsson, Ivana Magić, Josefine Bostner, Christine Dyrager, Fredrik Lysholm, Anna‐Lotta Hallbeck, Olle Stål, Patrik Lundström · 2015 · PLoS ONE
- Cell-surface major vault protein promotes cancer progression through harboring mesenchymal and intermediate circulating tumor cells in hepatocellular carcinomasHyun Min Lee, Jae‐Won Joh, Se-Ri Seo, Won‐Tae Kim, Min Kyu Kim, Hong Seo Choi, So Young Kim, Young‐Joo Jang, Dong Hyun Sinn, Gyu‐Seong Choi et al. · 2017 · Scientific Reports
- Consensus molecular subtype 4 (CMS4)-targeted therapy in primary colon cancer: a proof-of-concept studyPeters, Niek A., Constantinides, Alexander, Ubink, Inge, van Kuik, Joyce, Bloemendal, Haiko J., van Dodewaard, Joyce M., Brink, Menno A., Schwartz, Thijs P., Lolkema, Martijn P.J.K., Lacle, Miangela M. et al. · 2022 · Frontiers in Oncology
- Functional Interactions Between rsks-1 /S6K, glp-1 /Notch, and Regulators of Caenorhabditis elegans Fertility and Germline Stem Cell MaintenanceDebasmita Roy, David J. Kahler, Chi Yun, E. Jane Albert Hubbard · 2018 · G3 Genes Genomes Genetics
- Partial substitution of fish meal with soy protein concentrate in commercial diets for juvenile swimming crab, Portunus trituberculatusXuexi Wang, Ye Yuan, Chen-chen Li, Fan Zhou, Min Jin, Peng Sun, Tingting Zhu, Xueyan Ding, Qicun Zhou · 2019 · Animal Feed Science and Technology
- Revealing Dynamic Protein Acetylation across Subcellular CompartmentsJosue Baeza, Alexis J. Lawton, Jing Fan, Michael J. Smallegan, Ian Lienert, Tejas Gandhi, Oliver M. Bernhardt, Lukas Reiter, John M. Denu · 2020 · Journal of Proteome Research
- Kinetics of osmotic stress regulate a cell fate switch of cell survivalAlexander Thiemicke, Gregor Neuert · 2021 · Science Advances
- Exercise Training as Therapy for Cancer-Induced Cardiac CachexiaJ.M.M. Antunes, Rita M. Ferreira, Daniel Moreira‐Gonçalves · 2018 · Trends in Molecular Medicine
- Genetics and Pharmacology of LongevityJorge Iván Castillo-Quan, Kerri J. Kinghorn, Ivana Bjedov · 2015 · Advances in genetics
- Roles of Sestrin2 and Ribosomal Protein S6 in Transient Global Ischemia-Induced Hippocampal Neuronal InjuryYao‐Chung Chuang, Jenq‐Lin Yang, Ding‐I Yang, Tsu‐Kung Lin, Chia‐Wei Liou, Shang‐Der Chen · 2015 · International Journal of Molecular Sciences
- Oxysterol-binding protein–related protein 5 (ORP5) promotes cell proliferation by activation of mTORC1 signalingXiming Du, Armella Zadoorian, Ivan Lukmantara, Yanfei Qi, Andrew John Brown, Hongyuan Yang · 2018 · Journal of Biological Chemistry
- Glibenclamide Targets Sulfonylurea Receptor 1 to Inhibit p70S6K Activity and Upregulate KLF4 Expression to Suppress Non-Small Cell Lung CarcinomaKexin Xu, Geng Sun, Min Li, Hongling Chen, Zuhao Zhang, Xixi Qian, Ping Li, Lin Xu, Wenbin Huang, Xuerong Wang · 2019 · Molecular Cancer Therapeutics
- Downregulation of NUSAP1 suppresses cell proliferation, migration, and invasion via inhibiting mTORC1 signalling pathway in gastric cancerYugang Ge, Qiang Li, Linling Lin, Mingkun Jiang, Liang Shi, Biao Wang, Li Yang, Zekuan Xu · 2019 · Cell Biochemistry and Function
- Synthetic lethality by targeting the RUVBL1/2-TTT complex in mTORC1-hyperactive cancer cellsSeung Ho Shin, Ji Su Lee, Jiamin Zhang, Sungbin Choi, Žarko Bošković, Ran Zhao, Mengqiu Song, Rui Wang, Jie Tian, Mee‐Hyun Lee et al. · 2020 · Science Advances
- EGB761 ameliorates chronic cerebral hypoperfusion-induced cognitive dysfunction and synaptic plasticity impairmentZhaohui Yao, Jing Wang, Jingping Yuan, Kai Xiao, Shaofeng Zhang, Yanchun Xie, Junhua Mei · 2021 · Aging
- Inhibition of Akt Phosphorylation Diminishes Mitochondrial Biogenesis Regulators, Tricarboxylic Acid Cycle Activity and Exacerbates Recognition Memory Deficit in Rat Model of Alzheimer’s DiseaseFatemeh Shaerzadeh, Fereshteh Motamedi, Fariba Khodagholi · 2014 · Cellular and Molecular Neurobiology
- The Effects of 5-Fluorouracil on the Proteome of Colon Cancer CellsConsuelo Marín‐Vicente, Yaroslav Lyutvinskiy, Patricia Romans Fuertes, Roman A. Zubarev, Neus Visa · 2013 · Journal of Proteome Research
- Phosphorylation and degradation of S6K1 (p70S6K1) in response to persistent JNK1 ActivationJin Zhang, Zhan‐Guo Gao, Jianping Ye · 2013 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
- Pharmacological targeting of mammalian target of rapamycin inhibits ovarian granulosa cell tumor growthCharlène Rico, Marie-Noëlle Laguë, Pavine L. C. Lefèvre, Mayra F. Tsoi, Aurore Dodelet-Devillers, Vikas Kumar, Évelyne Lapointe, Marilène Paquet, Marie‐Ève Nadeau, Derek Boerboom · 2012 · Carcinogenesis
- Dietary interventions that reduce mTOR activity rescue autistic-like behavioral deficits in miceJiangbo Wu, Caroline G. M. de Theije, Sofia Lopes da Silva, Suzanne Abbring, Hilma J. van der Horst, Laus M. Broersen, Linette E. M. Willemsen, Martien J. Kas, Johan Garssen, Aletta D. Kraneveld · 2016 · Brain Behavior and Immunity
- Genome-wide selection signatures address trait specific candidate genes in cattle indigenous to arid regions of IndiaNidhi Sukhija, Anoop Anand Malik, M. Joel Devadasan, Aishwarya Dash, Kangabam Bidyalaxmi, D. Ravi Kumar, M. Kousalaya Devi, Anjali Choudhary, K K Kanaka, Rekha Sharma et al. · 2023 · Animal Biotechnology
- Largen: A Molecular Regulator of Mammalian Cell Size ControlKazuo Yamamoto, Valentina Gandin, Masato Sasaki, Susan A. McCracken, Wanda Li, Jennifer Silvester, Andrew Elia, Feng Wang, Yosuke Wakutani, Roumiana Alexandrova et al. · 2014 · Molecular Cell