An essential role for functional lysosomes in ferroptosis of cancer cells

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

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Regulation of Ferroptotic Cancer Cell Death by GPX4

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Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

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Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

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Two to tango: Regulation of Mammalian iron metabolism

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Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy

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A Mitochondrial Protein Compendium Elucidates Complex I Disease Biology

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Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells.

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Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity

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Regulated necrosis: the expanding network of non-apoptotic cell death pathways

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Ferroptosis in Carcinoma: Regulatory Mechanisms and New Method for Cancer Therapy

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Cathepsin B is an executioner of ferroptosis

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Targeting ferroptosis synergistically sensitizes apoptotic sonodynamic anti-tumor nanotherapy

Zhou, L., Dong, C., Ding, L., Feng, W., Yu, L., Cui, X., & Chen, Y. (2021) · Nano Today · doi:10.1016/j.nantod.2021.101212 · Cited by 95

The Achilles’ heel of cancer: targeting tumors via lysosome-induced immunogenic cell death

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Emerging role of immunogenic cell death in cancer immunotherapy

Arimoto, K., Miyauchi, S., Liu, M., & Zhang, D. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1390263 · Cited by 103

Ferroptosis: Biological Rust of Lipid Membranes

Hassannia, B., Coillie, S. V., & Berghe, T. V. (2020) · Antioxidants and Redox Signaling · doi:10.1089/ars.2020.8175 · Cited by 93

Ferroptosis and Its Multifaceted Role in Cancer: Mechanisms and Therapeutic Approach

Chen, H., Wang, C., Liu, Z., He, X., Tang, W., He, L., Feng, Y., Liu, D., Yin, Y., & Li, T. (2022) · Antioxidants · doi:10.3390/antiox11081504 · Cited by 92

The role of ferroptosis in intervertebral disc degeneration

Fan, C., Chu, G., Yu, Z., Ji, Z., Kong, F., Yao, L., Wang, J., Geng, D., Wu, X., & Mao, H. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1219840 · Cited by 94

SLC7A11 is an unconventional H+ transporter in lysosomes

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Ferritinophagy, a form of autophagic ferroptosis: New insights into cancer treatment

Sun, K., Li, C., Liao, S., Yao, X., Ouyang, Y., Liu, Y., Wang, Z., Li, Z., & Yao, F. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.1043344 · Cited by 101

Organelle-specific analysis of labile Fe( ii ) during ferroptosis by using a cocktail of various colour organelle-targeted fluorescent probes

Hirayama, T., Miki, A., & Nagasawa, H. (2018) · Metallomics · doi:10.1039/c8mt00212f · Cited by 90

O-GlcNAcylated c-Jun antagonizes ferroptosis via inhibiting GSH synthesis in liver cancer

Chen, Y., Zhu, G., Liu, Y., Wu, Q., Zhang, X., Bian, Z., Zhang, Y., Pan, Q., & Sun, F. (2019) · Cellular Signalling · doi:10.1016/j.cellsig.2019.109384 · Cited by 92

Broadening horizons: the multifaceted functions of ferroptosis in kidney diseases

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Ferroptosis in viral infection: the unexplored possibility

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FIN56, a novel ferroptosis inducer, triggers lysosomal membrane permeabilization in a TFEB-dependent manner in glioblastoma

Zhang, X., Guo, Y., Li, H., & Han, L. (2021) · Journal of Cancer · doi:10.7150/jca.58500 · Cited by 91

Artesunate induces ferroptosis via modulation of p38 and ERK signaling pathway in glioblastoma cells

Song, Q., Peng, S., Che, F., & Zhu, X. (2022) · Journal of Pharmacological Sciences · doi:10.1016/j.jphs.2022.01.007 · Cited by 87

Necroptosis: A new way of dying?

Hanson, B. (2016) · Cancer Biology & Therapy · doi:10.1080/15384047.2016.1210732 · Cited by 93

High-Throughput Screening for the Discovery of Iron Homeostasis Modulators Using an Extremely Sensitive Fluorescent Probe

Hirayama, T., Niwa, M., Hirosawa, S., & Nagasawa, H. (2020) · ACS Sensors · doi:10.1021/acssensors.0c01445 · Cited by 90

Positive and Negative Regulation of Ferroptosis and Its Role in Maintaining Metabolic and Redox Homeostasis

Sharma, A., & Flora, S. J. S. (2021) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2021/9074206 · Cited by 88

Organelle-Specific Mechanisms in Crosstalk between Apoptosis and Ferroptosis

Wu, P., Zhang, X., Duan, D., & Жао, Л. (2023) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2023/3400147 · Cited by 92

Ferroptosis caused by cysteine insufficiency and oxidative insult

Fujii, J., Homma, T., & Kobayashi, S. (2019) · Free Radical Research · doi:10.1080/10715762.2019.1666983 · Cited by 86

Effective ferroptotic small-cell lung cancer cell death from SLC7A11 inhibition by sulforaphane

Iida, Y., Okamoto-Κatsuyama, M., Maruoka, S., Mizumura, K., Shimizu, T., Shikano, S., Hikichi, M., Takahashi, M., Tsuya, K., Okamoto, S., et al. (2020) · Oncology Letters · doi:10.3892/ol.2020.12332 · Cited by 84

Ferroptosis in Neurons and Cancer Cells Is Similar But Differentially Regulated by Histone Deacetylase Inhibitors

Zille, M., Kumar, A., Kundu, N., Bourassa, M. W., Wong, V. S. C., Willis, D. E., Karuppagounder, S. S., & Ratan, R. R. (2019) · eNeuro · doi:10.1523/eneuro.0263-18.2019 · Cited by 84

Swine influenza virus triggers ferroptosis in A549 cells to enhance virus replication

Cheng, J., Tao, J., Li, B., Shi, Y., & Liu, H. (2022) · Virology Journal · doi:10.1186/s12985-022-01825-y · Cited by 81

Targeted p53 on Small-Molecules-Induced Ferroptosis in Cancers

Zhang, W., Gai, C., Ding, D., Wang, F., & Li, W. (2018) · Frontiers in Oncology · doi:10.3389/fonc.2018.00507 · Cited by 78

t-BuOOH induces ferroptosis in human and murine cell lines

Wenz, C., Faust, D., Linz, B., Turmann, C., Nikolova, T., Bertin, J., Gough, P. J., Wipf, P., Schröder, A. S., Krautwald, S., et al. (2017) · Archives of Toxicology · doi:10.1007/s00204-017-2066-y · Cited by 79

Targeting Ferroptosis Pathway to Combat Therapy Resistance and Metastasis of Cancer

Liu, X., Zhang, Y., Wu, X., Xu, F., Ma, H., Wu, M., & Xia, Y. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.909821 · Cited by 78

Engineering dual catalytic nanomedicine for autophagy-augmented and ferroptosis-involved cancer nanotherapy

Li, Z., Wang, C., Dai, C., Hu, R., Ding, L., Feng, W., Huang, H., Wang, Y., Bai, J., & Chen, Y. (2022) · Biomaterials · doi:10.1016/j.biomaterials.2022.121668 · Cited by 72

GPX4 overexpressed non-small cell lung cancer cells are sensitive to RSL3-induced ferroptosis

Kim, J.-W., Min, D. W., Kim, D., Kim, J., Kim, J. M., Lim, H., & Lee, J.-Y. (2023) · Scientific Reports · doi:10.1038/s41598-023-35978-9 · Cited by 72

Ferroptosis and its Role in Gastric Cancer

Gu, R., Xia, Y., Li, P., Zou, D., Lu, K., Ren, L., Zhang, H., & Sun, Z. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.860344 · Cited by 75

Lysosome signaling in cell survival and programmed cell death for cellular homeostasis

Patra, S., Patil, S., Klionsky, D. J., & Bhutia, S. K. (2022) · Journal of Cellular Physiology · doi:10.1002/jcp.30928 · Cited by 69

Emerging Mechanisms and Targeted Therapy of Ferroptosis in Neurological Diseases and Neuro-oncology

Wang, Y., Tang, B., Zhu, J., Yu, J., Hui, J., Xia, S., & Ji, J. (2022) · International Journal of Biological Sciences · doi:10.7150/ijbs.72251 · Cited by 69

Ferroptosis and Its Potential Role in Metabolic Diseases: A Curse or Revitalization?

Duan, J.-Y., Lin, X., Xu, F., Shan, S., Guo, B., Li, F., Wang, Y., Zheng, M.-H., Xu, Q.-S., Lei, L.-M., et al. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.701788 · Cited by 69

Underlying Mechanism of Lysosomal Membrane Permeabilization in CNS Injury: A Literature Review

Xiang, L., Lou, J., Zhao, J., Geng, Y., Zhang, J., Wu, Y., Zhao, Y., Tao, Z., Yao, L., Qi, J., et al. (2024) · Molecular Neurobiology · doi:10.1007/s12035-024-04290-6 · Cited by 71

Antioxidant Systems as Modulators of Ferroptosis: Focus on Transcription Factors

Punziano, C., Trombetti, S., Cesaro, E., Grosso, M., & Faraonio, R. (2024) · Antioxidants · doi:10.3390/antiox13030298 · Cited by 75

Nanomedicine enables autophagy-enhanced cancer-cell ferroptosis

Yang, J., Ding, L., Yu, L., Wang, Y., Ge, M., Jiang, Q., & Chen, Y. (2020) · 中国科学通报：英文版 · doi:10.1016/j.scib.2020.10.021 · Cited by 65

Emerging roles of ferroptosis in liver pathophysiology

Kim, K. M., Cho, S. S., & Ki, S. H. (2020) · Archives of Pharmacal Research · doi:10.1007/s12272-020-01273-8 · Cited by 62

Molecular Mechanisms of Ferroptosis and Its Roles in Hematologic Malignancies

Zhao, Y., Huang, Z., & Peng, H. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.743006 · Cited by 62

Oxidative Metabolism as a Cause of Lipid Peroxidation in the Execution of Ferroptosis

Fujii, J., & Imai, H. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25147544 · Cited by 65

Mechanisms of ferroptosis sensitization and resistance

Lee, W. C., & Dixon, S. J. (2025) · Developmental Cell · doi:10.1016/j.devcel.2025.02.004 · Cited by 61

Ferroptosis: A New Road towards Cancer Management

Bano, I., Horký, P., Abbas, S. Q., Majid, M., Bilal, A. H. M., Ali, F., Behl, T., Hassan, S. S. U., & BUNGAU, S. G. (2022) · Molecules · doi:10.3390/molecules27072129 · Cited by 63

Ferroptosis: The Silver Lining of Cancer Therapy

Tang, Z., Huang, Z., Huang, Y., Chen, Y., Huang, M., Liu, H., Ye, Q. A., Zhao, J., & Jia, B. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.765859 · Cited by 62

Ferroptosis in Hepatocellular Carcinoma: Mechanisms, Drug Targets and Approaches to Clinical Translation

Bekric, D., Ocker, M., Mayr, C., Stintzing, S., Ritter, M., Kiesslich, T., & Neureiter, D. (2022) · Cancers · doi:10.3390/cancers14071826 · Cited by 58

Oncology Therapeutics Targeting the Metabolism of Amino Acids

Muhammad, N., Lee, H. M., & Kim, J. (2020) · Cells · doi:10.3390/cells9081904 · Cited by 59

Ferroptosis in tumor immunity and therapy

Gong, C., Ji, Q., Wu, M., Tu, Z., Lei, K., Luo, M., Liu, J., Lin, L., Li, K., Li, J., et al. (2022) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.17529 · Cited by 56

Targeting lipid metabolism for ferroptotic cancer therapy

Luo, M., Yan, J., Hu, X., Li, H., Li, H., Liu, Q., Chen, Y., & Zou, Z. (2022) · APOPTOSIS · doi:10.1007/s10495-022-01795-0 · Cited by 62

Mobilization of iron from ferritin: New steps and details

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Superoxide-mediated ferroptosis in human cancer cells induced by sodium selenite

Subburayan, K., Thayyullathil, F., Pallichankandy, S., Cheratta, A. R., & Galadari, S. (2020) · Translational Oncology · doi:10.1016/j.tranon.2020.100843 · Cited by 57

Ferroptosis and musculoskeletal diseases: “Iron Maiden” cell death may be a promising therapeutic target

Zhang, Y., Huang, X., Qi, B., Sun, C., Sun, K., Liu, N., Zhu, L., & Wei, X. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.972753 · Cited by 58

Phospholipid oxidation products in ferroptotic myocardial cell death

Stamenković, A., Pierce, G. N., & Ravandi, A. (2019) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00076.2019 · Cited by 57

Dynamic Regulation of Ferroptosis by Lipid Metabolism

Naowarojna, N., Wu, T. W., Pan, Z., Li, M., Han, J. R., & Zou, Y. (2023) · Antioxidants and Redox Signaling · doi:10.1089/ars.2023.0278 · Cited by 56

Autophagy and cancer treatment: four functional forms of autophagy and their therapeutic applications

Bai, Z., Peng, Y., Ye, X., Liu, Z., Li, Y., & Ma, L. (2022) · Journal of Zhejiang University SCIENCE B · doi:10.1631/jzus.b2100804 · Cited by 54

Lysosome-Mitochondrial Crosstalk in Cellular Stress and Disease

Kiraly, S., Stanley, J., & Eden, E. R. (2025) · Antioxidants · doi:10.3390/antiox14020125 · Cited by 58

Sanguinarine Represses the Growth and Metastasis of Non-small Cell Lung Cancer by Facilitating Ferroptosis

Xu, R., Wu, J., Luo, Y., Wang, Y., Tian, J., Teng, W., Zhang, B., Fang, Z., & Li, Y. (2022) · Current Pharmaceutical Design · doi:10.2174/1381612828666220217124542 · Cited by 51

Ferroptosis of Endothelial Cells in Vascular Diseases

Zhang, H., Zhou, S., Sun, M., Hua, M., Liu, Z., Mu, G., Wang, Z., Xiang, Q., & Cui, Y. (2022) · Nutrients · doi:10.3390/nu14214506 · Cited by 50

Pirin is a nuclear redox-sensitive modulator of autophagy-dependent ferroptosis

Hu, N., Bai, L., Dai, E., Han, L., Kang, R., Li, H., & Tang, D. (2020) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2020.12.066 · Cited by 49

Ferroptosis, a Regulated Form of Cell Death, as a Target for the Development of Novel Drugs Preventing Ischemia/Reperfusion of Cardiac Injury, Cardiomyopathy and Stress-Induced Cardiac Injury

Ryabov, V. V., Маслов, Л. Н., Вышлов, Е. В., Mukhomedzyanov, А. V., Kilin, M., Gusakova, S. V., Энхэевна, Г. А., & Panteleev, O. O. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25020897 · Cited by 48

Diverse cytoprotective actions of vitamin E isoforms- role as peroxyl radical scavengers and complementary functions with selenoproteins

Saito, Y. (2021) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2021.08.234 · Cited by 47

Ferroptosis-Inducing Nanomedicine for Cancer Therapy

Wang, Y., Liu, T., Li, X., Sheng, H., Ma, X., & Hao, L. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.735965 · Cited by 49

Targeting ferroptosis in osteosarcoma

Zhao, J., Zhao, Y., Ma, X., Zhang, B., & Feng, H. (2021) · Journal of bone oncology · doi:10.1016/j.jbo.2021.100380 · Cited by 48

Correlation of Ferroptosis and Other Types of Cell Death in Neurodegenerative Diseases

Dang, X., Huan, X., Du, X., Chen, X., Bi, M., Yan, C., Jiao, Q., & Jiang, H. F. (2022) · Neuroscience Bulletin · doi:10.1007/s12264-022-00861-6 · Cited by 46

Ferroptosis in Cardiovascular Diseases: Current Status, Challenges, and Future Perspectives

Guo, Y., Lu, C., Hu, K., Cai, C., & Wang, W. (2022) · Biomolecules · doi:10.3390/biom12030390 · Cited by 45

Ferroptosis triggers airway inflammation in asthma

Li, M., Li, M., Hou, Y., He, H., Jiang, R., Wang, C., & Sun, S. (2023) · Therapeutic Advances in Respiratory Disease · doi:10.1177/17534666231208628 · Cited by 48

Regulated cell death and its role in Alzheimer’s disease and amyotrophic lateral sclerosis

Thal, D. R., Gawor, K., & Moonen, S. (2024) · Acta Neuropathologica · doi:10.1007/s00401-024-02722-0 · Cited by 50

Ferroptosis Mechanisms Involved in Hippocampal-Related Diseases

Wang, X., Wang, Z., Cao, J., Dong, Y., & Chen, Y. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22189902 · Cited by 43

Molecular mechanisms of ferroptosis and its role in prostate cancer therapy

Wang, S., Wei, W., Ma, N., Qu, Y., & Liu, Q. (2022) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2022.103732 · Cited by 44

miR-135b-3p Promotes Cardiomyocyte Ferroptosis by Targeting GPX4 and Aggravates Myocardial Ischemia/Reperfusion Injury

Sun, W., Shi, R., Guo, J., Wang, H., Shen, L., Shi, H., Yu, P., & Chen, X. (2021) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2021.663832 · Cited by 43

G3BP1 coordinates lysophagy activity to protect against compression‐induced cell ferroptosis during intervertebral disc degeneration

Li, S., Liao, Z.-W., Yin, H., Liu, O., Hua, W.-B., Wu, X.-H., Zhang, Y.-K., Gao, Y., & Yang, C. (2022) · Cell Proliferation · doi:10.1111/cpr.13368 · Cited by 38

Ferroptotic agent‐induced endoplasmic reticulum stress response plays a pivotal role in the autophagic process outcome

Lee, Y., Kalishwaralal, K., Park, Y. S., Makala, H., Watkins, S. C., Choudry, H. A., Bartlett, D. L., Kwon, Y. T., & Lee, Y. J. (2020) · Journal of Cellular Physiology · doi:10.1002/jcp.29571 · Cited by 44

Abundant expression of ferroptosis-related SAT1 is related to unfavorable outcome and immune cell infiltration in low-grade glioma

Mou, Y., Zhang, L., Liu, Z., & Song, X. (2022) · BMC Cancer · doi:10.1186/s12885-022-09313-w · Cited by 42

Ferroptosis inducers: A new frontier in cancer therapy

Ma, W., Hu, N., Xu, W., Zhao, L., Tian, C., & Kamei, K. (2024) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2024.107331 · Cited by 44

Lipid metabolism in ferroptosis and ferroptosis-based cancer therapy

Sun, Y., Xue, Z., Huang, T., Che, X., & Wu, G. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.941618 · Cited by 44

Ferroptosis, autophagy, tumor and immunity

Xie, Y., Zhou, Y., Wang, J., Lijuan, D., Ren, Y., & Liu, F. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e19799 · Cited by 40

The complex interplay between autophagy and cell death pathways

Ploumi, C., Papandreou, M.-E., & Tavernarakis, N. (2022) · Biochemical Journal · doi:10.1042/bcj20210450 · Cited by 39

Oxidative damage of lysosomes in regulated cell death systems: Pathophysiology and pharmacologic interventions

Nagakannan, P., Tabeshmehr, P., & Eftekharpour, E. (2020) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2020.04.001 · Cited by 41

Redox Epiphospholipidome in Programmed Cell Death Signaling: Catalytic Mechanisms and Regulation

Kagan, V. E., Tyurina, Y. Y., Vlasova, I. I., Kapralov, A. A., Amoscato, A. A., Anthonymuthu, T. S., Tyurin, V. A., Shrivastava, I. H., Cinemre, F. B. S., Lamade, A. M., et al. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.628079 · Cited by 39

Ferroptosis in osteosarcoma: A promising future

Liu, X., Du, S., Wang, S., & Ye, K. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.1031779 · Cited by 39

Mitochondrial transplantation rescues neuronal cells from ferroptosis

Chen, T., Majerníková, N., Marmolejo-Garza, A., Trombetta-Lima, M., Sabogal-Guáqueta, A. M., Zhang, Y., ten Kate, R., Zuidema, M., Mulder, P. P. M. F. A., den Dunnen, W. F. A., et al. (2023) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2023.07.034 · Cited by 37

Improving lysosomal ferroptosis with NMN administration protects against heart failure

Yagi, M., Do, Y., Hirai, H., Miki, K., Toshima, T., Fukahori, Y., Setoyama, D., Abe, C., Nabeshima, Y., Kang, D., et al. (2023) · Life Science Alliance · doi:10.26508/lsa.202302116 · Cited by 39

Potential mechanism of ferroptosis in pancreatic cancer (Review)

Chen, G., Guo, G., Zhou, X., & Chen, H. (2019) · Oncology Letters · doi:10.3892/ol.2019.11159 · Cited by 37

The Role of Ferroptosis in Cardiovascular Disease and Its Therapeutic Significance

Chen, Z., Yan, Y., Qi, C., Liu, J., Li, L., & Wang, J. (2021) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2021.733229 · Cited by 36

The Interplay Between Autophagy and Regulated Necrosis

Zhang, L., Cui, T., & Wang, X. (2022) · Antioxidants and Redox Signaling · doi:10.1089/ars.2022.0110 · Cited by 39

Erastin triggers autophagic death of breast cancer cells by increasing intracellular iron levels

Li, M., Wang, X., Lu, S., He, C. H., Wang, C., Wang, L., Wang, X., Ge, P., & Song, D. E. (2020) · Oncology Letters · doi:10.3892/ol.2020.11918 · Cited by 34

Lysoptosis is an evolutionarily conserved cell death pathway moderated by intracellular serpins

Luke, C. J., Markovina, S. T., Good, M. L., Wight, I. E., Thomas, B. J., Linneman, J. M., Lanik, W. E., Koroleva, O., Coffman, M. R., Miedel, M. T., et al. (2022) · Communications Biology · doi:10.1038/s42003-021-02953-x · Cited by 36

Phenazine derivatives attenuate the stemness of breast cancer cells through triggering ferroptosis

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Topology regulation of nanomedicine for autophagy-augmented ferroptosis and cancer immunotherapy

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A guide to ferroptosis, the biological rust of cellular membranes

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The Role of Nrf2 in the Regulation of Mitochondrial Function and Ferroptosis in Pancreatic Cancer

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Adaptive Changes Allow Targeting of Ferroptosis for Glioma Treatment

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Quercetin inhibits the progression of endometrial HEC-1-A cells by regulating ferroptosis—a preliminary study

Li, X., Zhu, Q., Ma, M., & Guo, H. (2022) · European journal of medical research · doi:10.1186/s40001-022-00934-2 · Cited by 33

Radiotherapy-activated NBTXR3 nanoparticles promote ferroptosis through induction of lysosomal membrane permeabilization

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A novel pharmacological mechanism of anti-cancer drugs that induce pyroptosis

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Iron metabolism and ferroptosis in diabetic bone loss: from mechanism to therapy

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Ferroptosis in hepatocellular carcinoma: Mechanisms and therapeutic implications

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Senescence-associated lysosomal dysfunction impairs cystine deprivation-induced lipid peroxidation and ferroptosis

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Effects of Jiawei Shaoyao‐Gancao Decoction and Its Drug‐Containing Serum on Proliferation, Apoptosis, and Ultrastructure of Human Adenomyosis Foci Cells

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Ferroptosis Meets Cell–Cell Contacts

Dietrich, C., & Hofmann, T. G. (2021) · Cells · doi:10.3390/cells10092462 · Cited by 30

Mechanisms of ferroptosis in chronic kidney disease

Zhuo, W.-Q., Wen, Y., Luo, H., Luo, Z., & Wang, L. (2022) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2022.975582 · Cited by 29

Neratinib inhibits proliferation and promotes apoptosis of acute myeloid leukemia cells by activating autophagy‐dependent ferroptosis

Ma, H., Liu, Y., Miao, Z., Cheng, S., Zhu, Y., Wu, Y., Fan, X., Yang, J., Li, X., & Guo, L. (2022) · Drug Development Research · doi:10.1002/ddr.21983 · Cited by 32

Iron accumulation and lipid peroxidation: implication of ferroptosis in diabetic cardiomyopathy

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Lysosome: a critical hub for ferroptosis regulation

Chen, X. (2026) · Trends in Cell Biology · doi:10.1016/j.tcb.2026.03.007 · Cited by 7

Activation of lysosomal iron triggers ferroptosis in cancer

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Pharmacological approaches for targeting lysosomes to induce ferroptotic cell death in cancer

Ji, F., Wang, Z.-X., Bin, J.-L., Chen, Y., Ma, J., Deng, J.-H., Huang, X., Zhou, J., & Lu, G. (2024) · Cancer Letters · doi:10.1016/j.canlet.2024.216728 · Cited by 38

Lipoxygenase‐mediated generation of lipid peroxides enhances ferroptosis induced by erastin and RSL3

Shintoku, R., Takigawa, Y., Yamada, K., Kubota, C., Yoshimoto, Y., Takeuchi, T., Koshiishi, I., & Torii, S. (2017) · Cancer Science · doi:10.1111/cas.13380 · Cited by 461

The lysosome as a master regulator of iron metabolism

Rizzollo, F., More, S., Vangheluwe, P., & Agostinis, P. (2021) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2021.07.003 · Cited by 243