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Genes to cells edited by Jun-ichi Tomizawa, Blackwell Science Ltd. Institutional: £218.00 (Europe), £242.00 (Rest of World), US$382.00 (USA and Canada). Individual: £65.00 (Europe), £72.00 (Rest of World), US$114.00 (USA and Canada) ISSN 1356 9597

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Nutrients, via the Tor proteins, stimulate the association of Tap42 with type 2A phosphatases.Preprint

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AMP-activated protein kinase is activated by low glucose in cell lines derived from pancreatic β cells, and may regulate insulin release

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The TOR nutrient signalling pathway phosphorylates NPR1 and inhibits turnover of the tryptophan permease

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TOR kinase domains are required for two distinct functions, only one of which is inhibited by rapamycin

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mTOR integrates amino acid- and energy-sensing pathways

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The Growing Role of mTOR in Neuronal Development and Plasticity

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Amino Acid Sensing by mTORC1: Intracellular Transporters Mark the Spot

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Heat shock response and autophagy—cooperation and control

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New roles for the LKB1→AMPK pathway

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Berberine-stimulated glucose uptake in L6 myotubes involves both AMPK and p38 MAPK

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Arginine Deprivation as a Targeted Therapy for Cancer

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TOR Signaling

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Structure and Physiological Actions of Ghrelin

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Amino acid signalling and the integration of metabolism

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Molecular mechanism and regulation of autophagy1

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Chapter 1 Physiological Roles of Ribosomal Protein S6: One of Its Kind

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Mammalian Target of Rapamycin: Discovery of Rapamycin Reveals a Signaling Pathway Important for Normal and Cancer Cell Growth

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Arctigenin Effectively Ameliorates Memory Impairment in Alzheimer's Disease Model Mice Targeting Both -Amyloid Production and Clearance

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Mammalian target of rapamycin (mTOR) inhibition as a potential antiepileptogenic therapy: from tuberous sclerosis to common acquired epilepsies.

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mTOR-Dependent Cell Survival MechanismsPreprint

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Autophagy: Regulation and role in disease

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The Role of AMPK and mTOR in Nutrient Sensing in Pancreatic β-Cells

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Dietary Energy Restriction Modulates the Activity of AMP-Activated Protein Kinase, Akt, and Mammalian Target of Rapamycin in Mammary Carcinomas, Mammary Gland, and Liver

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Activated FOXO-mediated insulin resistance is blocked by reduction of TOR activity

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Histological evaluation of AMPK signalling in primary breast cancer

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PolyMetformin combines carrier and anticancer activities for in vivo siRNA delivery

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Rosiglitazone suppresses human lung carcinoma cell growth through PPARγ-dependent and PPARγ-independent signal pathways

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Mitochondria and cancer: is there a morphological connection?

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AMP-Activated Protein Kinase: A Key Stress Signaling Pathway in the Heart

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Adenosine induces apoptosis in the human gastric cancer cells via an intrinsic pathway relevant to activation of AMP-activated protein kinase

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The AMP-Activated Protein Kinase KIN10 Is Involved in the Regulation of Autophagy in Arabidopsis

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Spatial Memory Formation and Memory-Enhancing Effect of Glucose Involves Activation of the Tuberous Sclerosis Complex–Mammalian Target of Rapamycin Pathway

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Estrogen as a key regulator of energy homeostasis and metabolic health

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Protein, amino acids and the control of food intake

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Influence of muscle glycogen availability on ERK1/2 and Akt signaling after resistance exercise in human skeletal muscle

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MicroRNA-125a Inhibits Autophagy Activation and Antimicrobial Responses during Mycobacterial Infection

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Therapeutics by Cytotoxic Metabolite Accumulation: Pemetrexed Causes ZMP Accumulation, AMPK Activation, and Mammalian Target of Rapamycin Inhibition

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5-Aminoimidazole-4-carboxamide riboside (AICAR) enhances GLUT2-dependent jejunal glucose transport: a possible role for AMPK

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Integration of hormonal and nutrient signals that regulate leptin synthesis and secretion

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The opposing actions of target of rapamycin and AMP-activated protein kinase in cell growth control.Preprint

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Nutrient sensing and metabolic decisions

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Aβ-induced formation of autophagosomes is mediated by RAGE-CaMKKβ-AMPK signaling

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Protein, amino acids, vagus nerve signaling, and the brain

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Hypoxia-Inducible Factor-1: A Critical Player in the Survival Strategy of Stressed Cells

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Resveratrol inhibits the proliferation and induces the apoptosis in ovarian cancer cells via inhibiting glycolysis and targeting AMPK/mTOR signaling pathway

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Important role for AMPKαl in limiting skeletal muscle cell hypertrophy

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Glucagon Represses Signaling through the Mammalian Target of Rapamycin in Rat Liver by Activating AMP-activated Protein Kinase

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Diminished overload-induced hypertrophy in aged fast-twitch skeletal muscle is associated with AMPK hyperphosphorylation

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PI3-kinase and TOR: PIKTORing cell growth

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Concurrent detection of autolysosome formation and lysosomal degradation by flow cytometry in a high-content screen for inducers of autophagy

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Chapter 3 Ribosomal Protein S6 Kinase

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Adenoviral proteins mimic nutrient/growth signals to activate the mTOR pathway for viral replication

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AMPK activation prevents excess nutrient-induced hepatic lipid accumulation by inhibiting mTORC1 signaling and endoplasmic reticulum stress response

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PPAR‐γAgonists and Their Effects on IGF‐I Receptor Signaling: Implications for Cancer

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mTOR inhibition modulates epileptogenesis, seizures and depressive behavior in a genetic rat model of absence epilepsy

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Regulation of ploidy and senescence by the AMPK‐related kinase NUAK1

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Interaction between the AMP-Activated Protein Kinase and mTOR Signaling Pathways

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mTOR integrates amino acid- and energy-sensing pathways

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AMPK Control of mTOR Signaling and Growth

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LKB1 and AMP-activated protein kinase control of mTOR signalling and growth

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Akt activates the mammalian target of rapamycin by regulating cellular ATP level and AMPK activity

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