The DOI matches its Crossref record; 84 of the 84 references it cites were found in a registry or an index.
Chemistry And Biological Effects Of Dietary Phenolic Compounds: Relevance To Cardiovascular Disease
Abstract
SUMMARY: 1. There has been considerable recent interest in the possibility that increased intake of dietary anti‐oxidants may protect against cardiovascular disease. This is partly due to the knowledge that oxidative events in vivo may play a role in the pathogenesis of atherosclerosis. 2. While dietary anti‐oxidants, such as vitamins E and C, have received considerable attention in this regard, relatively little is known about a similar anti‐oxidant role for plant‐derived polyphenolic compounds, such as the flavonoids and phenolic acids. A review of the distribution, bioavailability and biological activity of these compounds suggests that they may have a physiological role as anti‐oxidants. 3. Human trials on the anti‐oxidant effects of beverages rich in polyphenolics, such as red wine, fruit juice or tea, have been limited and results are, at present, inconclusive. This is due, in part, to poor methodologies available to measure oxidative damage in vivo. 4. There is a sound rationale for considering polyphenolics as important contributors to the dietary anti‐oxidant intake derived from fruits and vegetables. However, continuing research is needed using appropriate biomarkers of oxidant damage in vivo before these compounds can be conclusively considered as dietary anti‐oxidants with nutritional benefit.
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Cites
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Flavonoids--Chemistry, metabolism, cardioprotective effects, and dietary sources
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Cited by
Natural phenolics in the prevention of UV-induced skin damage. A review
Svobodová, A., Psotová, J., & Walterová, D. (2003) · Biomedical Papers · doi:10.5507/bp.2003.019 · Cited by 455
An Outlook on Chlorogenic Acids—Occurrence, Chemistry, Technology, and Biological Activities
Upadhyay, R., & Mohan Rao, L. J. (2013) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2011.576319 · Cited by 386
Loke, W. M., Proudfoot, J. M., Hodgson, J. M., McKinley, A. J., Hime, N., Magat, M., Stocker, R., & Croft, K. D. (2010) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/atvbaha.109.199687 · Cited by 284
Self-citationJacobo-Velázquez, D. A., González-Agüero, M., & Cisneros-Zevallos, L. (2015) · Scientific Reports · doi:10.1038/srep08608 · Cited by 238
Fruit juice consumption modulates antioxidative status, immune status and DNA damage
Bub, A., Watzl, B., Blockhaus, M., Briviba, K., Liegibel, U., Müller, H., Pool-Zobel, B. L., & Rechkemmer, G. (2003) · The Journal of Nutritional Biochemistry · doi:10.1016/s0955-2863(02)00255-3 · Cited by 233
Metadata
- Authors
- Morton, L. W., Caccetta, R. A., Puddey, I. B., & Croft, K. D.
- Venue
- Clinical and Experimental Pharmacology and Physiology
- Publisher
- Wiley
- Published
- 2000-03-11
- Volume
- 27
- Issue
- 3
- Pages
- 152-159
- ISSN
- 0305-1870 (ISSN-L)
- 1440-1681
- OpenAlex
- W1702241642
- Cited by
- 393
- References
- 84
- FWCI
- 6.46
- Type
- journal article
- Language
- en
- Open access
- closed
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- Morton, L. W., Caccetta, R. A., Puddey, I. B., & Croft, K. D. (2000). Chemistry And Biological Effects Of Dietary Phenolic Compounds: Relevance To Cardiovascular Disease. Clinical and Experimental Pharmacology and Physiology. https://doi.org/10.1046/j.1440-1681.2000.03214.x
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