Effects of tea tree oil on Escherichia coli
Abstract
Tea tree oil (TTO) stimulates autolysis in exponential and stationary phase cells of Escherichia coli. Electron micrographs of cells grown in the presence of TTO showed the loss of electron dense material, coagulation of cell cytoplasm and formation of extracellular blebs. Stationary phase cells demonstrated less TTO-stimulated autolysis and also had greater tolerance to TTO-induced cell death, compared to exponentially grown cells. It was also revealed that subpopulation of stationary phase cells demonstrated increased tolerance to TTO-bactericidal effects.
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Tea tree oil can cause E. coli to die without lysing the cell.
“For example, tea tree oil can cause E. coli to die without lysing the cell [65].”
From Effect of essential oils on pathogenic bacteria (2013) · cites this paper as [65]
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“…into the cytoplasmic membrane may interfere with the process of membraneassociated signal transduction and impair the function of some membrane proteins, resulting in changes to the architecture and composition of the cell wall (Okubo et al., 1989; Ikigai et al., 1990; Gustafson et al., 1998).”
BackgroundAntibacterial activity studies of plasma polymerised cineole films
Pegalajar‐Jurado, A., Easton, C. D., Styan, K. E., et al. (2014) · Journal of Materials Chemistry B · doi:10.1039/c4tb00633j · Cited by 43 · see citing works
Baral, B., & Mozafari, M. R. (2020) · ACS Pharmacology & Translational Science · doi:10.1021/acsptsci.0c00005 · Cited by 42 · see citing works
Aflatoxin B1 Occurrence, Detection and Toxicological Effects
Long, X.-D. (2019) · IntechOpen eBooks · doi:10.5772/intechopen.77925 · Cited by 43 · see citing works
Characterization and Biological Activities of Essential Oils of Some Species of Lamiaceae
Hussain, A. I. (2009) · HEC National Digital Library · Cited by 42 · see citing works
In vitro genotoxicity of Melaleuca alternifolia essential oil in human lymphocytes
Pereira, T. S., de Sant’Anna, J. R., Silva, E. L., Pinheiro, A. L., & de Castro‐Prado, M. A. A. (2013) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2013.11.045 · Cited by 38 · see citing works
Tea Tree Oil‐Induced Transcriptional Alterations in Staphylococcus aureus
Cuaron, J. A., Dulal, S., Song, Y., et al. (2012) · Phytotherapy Research · doi:10.1002/ptr.4738 · Cited by 40 · see citing works
“The overall bactericidal activity of TTO is attributed to its ability to denature proteins and alter membrane and cell wall structure and function (Carson et al., 2002; Carson et al., 2006; Carson and Riley, 1995; Cox et al., 1998; Cox et al., 2000; Gustafson et al., 1998; Sikkema et al., 1995).”
BackgroundInfluentialUse of Essential Oils and Their Components against Multidrug-Resistant Bacteria
Faleiro, M. L., & Miguel, M. G. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-398539-2.00006-9 · Cited by 39 · see citing works
Bactericidal action of lemon grass oil vapors and negative air ions
Tyagi, A. K., & Malik, A. (2011) · Innovative Food Science & Emerging Technologies · doi:10.1016/j.ifset.2011.09.007 · Cited by 39 · see citing works
Evaluation of the antibacterial effect of tea tree oil on Enterococcus faecalis and biofilm in vitro
Qi, J., Gong, M., Zhang, R., Song, Y.-M., Liu, Q., Zhou, H., Wang, J., & Mei, Y. (2021) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2021.114566 · Cited by 38 · see citing works
Ge, Y., & Ge, M. (2015) · Journal of Experimental Nanoscience · doi:10.1080/17458080.2015.1065013 · Cited by 38 · see citing works
“[1] However, it has proved that autolysis is a secondary event that occurs following TTO-induced cell death.[9] It was speculated that the antimicrobial activity of essential oil was significantly influenced by the composition of the bacterial membrane [47] and the Gram-negative bacteria had a strong resistance to TTO…”
Background
- Authors
- Gustafson, Liew, Chew, Markham, Bell, Wyllie, & Warmington
- Affiliations
- Curtin University (AU)
- Western Sydney University (AU)
- Southern Cross University (AU)
- Corresponding author
- Gustafson
- Venue
- Letters in Applied Microbiology
- Publisher
- Oxford University Press (OUP)
- Published
- 1998-03
- Volume
- 26
- Issue
- 3
- Pages
- 194-198
- ISSN
- 0266-8254 (ISSN-L)
- 1365-2673
- OpenAlex
- W1991343099
- Cited by
- 244
- References
- 0
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 7 · 2023: 6 · 2022: 8 · 2021: 15 · 2020: 11 · 2019: 15 · 2018: 12 · 2017: 14 · 2016: 19 · 2015: 6 · 2014: 18 · 2013: 15 · 2012: 12
- FWCI
- 10.30
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Letters in Applied Microbiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
- Physical Sciences › Chemistry › Organic Chemistry › Antimicrobial agents and applications
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Bacterial Genetics and Biotechnology
- Keywords
- tea tree oil, Escherichia coli, bacterial autolysis, stationary phase cells, bactericidal activity, cell morphology
- MeSH terms
- Bacteriolysis, Escherichia coli, Microscopy, Electron, Oils, Volatile, Tea
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