Activity of natural antimicrobial compounds against Escherichia coli and Salmonella enterica serovar Typhimurium
Abstract
AIMS: The objective of this study was to evaluate the inhibitory activity of several natural organic compounds alone or in combination with nisin against Escherichia coli and Salmonella Typhimurium. METHODS AND RESULTS: The minimum inhibitory concentration (MIC) of five natural organic compounds were determined, and the effect of their combinations with nisin was evaluated by the checkerboard assay using the Bioscreen C. As expected, nisin by itself showed no inhibition against either of the Gram-negative bacteria. Thymol was found to be the most effective with the lowest MIC values of 1.0 and 1.2 mmol 1-1 against Salm. Typhimurium and E. coli, respectively. After thymol, the antimicrobial order of the natural organic compounds was carvacrol > eugenol > cinnamic acid > diacetyl. However, the combination of nisin with the natural organic compounds did not result in the enhancement of their antimicrobial activities. On the contrary, combination of nisin with diacetyl against Salm. Typhimurium resulted in an antagonism of diacetyl activity. CONCLUSIONS: While the individual natural organic compounds showed inhibitory activity against the two Gram-negatives, their combinations with nisin showed no improvement of antimicrobial activity. SIGNIFICANCE AND IMPACT OF THE STUDY: This study shows the potential of the natural organic compounds to control E. coli and Salm. Typhimurium.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Diacetyl has been shown to exert antifungal and antibacterial effects at low pH.
“Diacetyl has been shown to exert antifungal and antibacterial effects at low pH [167,168].”
From Lactic Acid Bacteria in Raw-Milk Cheeses: From Starter Cultures to Probiotic Functions (2022) · cites this paper as [168]
Cites
The Journal of General Microbiology
(1985) · Microbiology · doi:10.1099/00221287-131-3-696 · Cited by 2,449 · see citing works
Characterization of the action of selected essential oil components on Gram-negative bacteria
Helander, I. M., Alakomi, H.-L., Latva-Kala, K., Mattila-Sandholm, T., Pol, I., Smid, E. J., Gorris, L. G. M., & von Wright, A. (1998) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf980154m · Cited by 1,664 · see citing works
Friedman, M., Henika, P. R., & Mandrell, R. E. (2002) · Journal of Food Protection · doi:10.4315/0362-028x-65.10.1545 · Cited by 1,128 · see citing works
Applications of the bacteriocin, nisin
Delves‐Broughton, J., Blackburn, P., Evans, R., & Hugenholtz, J. (1996) · Antonie van Leeuwenhoek · doi:10.1007/bf00399424 · Cited by 976 · see citing works
Antibacterial activity of some essential oil components against five foodborne pathogens
Kim, J., Marshall, M. R., & Wei, C.-I. (1995) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf00059a013 · Cited by 892 · cited 1× · see citing works
“…et al. 1996), whereas other natural compounds such as carvacrol, cinnamic acid, diacetyl, eugenol and thymol have been shown to exhibit inhibitory activity against numerous food related bacteria (Kim et al. 1995; Kang and Fung 1999; Friedman et al. 2002; Roller and Seedhar 2002; Walsh et al. 2003).”
BackgroundActivity and mechanisms of action of selected biocidal agents on Gram-positive and-negative bacteria
Walsh, S. E., Maillard, J.-Y., Russell, A. D., Catrenich, C. E., Charbonneau, D. L., & Bartolo, R. G. (2003) · Journal of Applied Microbiology · doi:10.1046/j.1365-2672.2003.01825.x · Cited by 527 · see citing works
Hurst, A. (1981) · Advances in applied microbiology · doi:10.1016/s0065-2164(08)70342-3 · Cited by 454 · see citing works
The Effect of Food Preservatives on pH Homeostasis in Escherichia coli
SALMOND, C. V., Kroll, R. G., & Booth, I. R. (1984) · Microbiology · doi:10.1099/00221287-130-11-2845 · Cited by 398 · see citing works
Methods for testing the efficacy of food antimicrobials
Davidson, P. M., & Parish, M. E. (1989) · Food technology · Cited by 337 · see citing works
Industry Perspectives on the Use of Natural Antimicrobials and Inhibitors for Food Applications
Gould, G. W. (1996) · Journal of Food Protection · doi:10.4315/0362-028x-59.13.82 · Cited by 231 · see citing works
Antimicrobial properties of diacetyl
Jay, J. M. (1982) · Applied and Environmental Microbiology · doi:10.1128/aem.44.3.525-532.1982 · Cited by 229 · see citing works
Hauben, K., Wuytack, E. Y., Soontjens, C. C. F., & Michiels, C. W. (1996) · Journal of Food Protection · doi:10.4315/0362-028x-59.4.350 · Cited by 217 · see citing works
Carvacrol and cinnamic acid inhibit microbial growth in fresh-cut melon and kiwifruit at 4o and 8oC
Roller, S. D., & Seedhar, P. (2002) · Letters in Applied Microbiology · doi:10.1046/j.1472-765x.2002.01209.x · Cited by 185 · see citing works
Permeability barrier of the Gram-negative bacterial outer membrane with special reference to nisin
Helander, I. M., & Mattila, T. (2000) · International Journal of Food Microbiology · doi:10.1016/s0168-1605(00)00307-x · Cited by 166 · see citing works
Inhibition of growth of some foodborne pathogenic bacteria by Capsicum annum extracts
Dorantes‐Álvarez, L., Colmenero-Solís, R. D. J., Hernandez, H., Mota, L., Jaramillo, M. E., Fernandez, E., & Solano, C. (2000) · International Journal of Food Microbiology · doi:10.1016/s0168-1605(00)00216-6 · Cited by 150 · see citing works
Natural antimicrobial systems and food preservation
Robinson, R. K. (1995) · Food Chemistry · doi:10.1016/0308-8146(95)90048-9 · Cited by 147 · see citing works
Effect of chelators and nisin produced in situ on inhibition and inactivation of Gram negatives
Boziaris, I. S., & Adams, M. R. (1999) · International Journal of Food Microbiology · doi:10.1016/s0168-1605(99)00139-7 · Cited by 143 · see citing works
Periago, P. M., & Moezelaar, R. (2001) · International Journal of Food Microbiology · doi:10.1016/s0168-1605(01)00461-5 · Cited by 141 · see citing works
ANTIMICROBIAL ACTIVITY OF SOME FOOD FLAVORING COMPOUNDS
Jay, J. M., & RIVERS, G. M. (1984) · Journal of Food Safety · doi:10.1111/j.1745-4565.1984.tb00609.x · Cited by 111 · see citing works
Terebiznik, M. R., Jagus, R. J., Cerrutti, P., de Huergo, M. S., & Pilosof, A. M. R. (2002) · Journal of Food Protection · doi:10.4315/0362-028x-65.8.1253 · Cited by 36 · see citing works
Kang, D., & Fung, D. Y. C. (1999) · Journal of Food Protection · doi:10.4315/0362-028x-62.9.975 · Cited by 36 · see citing works
Archer, M. H., Dillon, V. M., Campbell‐Platt, G., & Owens, J. D. (1996) · Food Control · doi:10.1016/0956-7135(96)00016-3 · Cited by 11 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Antibacterial and antifungal activities of thymol: A brief review of the literature
Marchese, A. E., Orhan, İ. E., Daglia, M., Barbieri, R., Lorenzo, A. D., Nabavi, S. F., Gortzi, O., Izadi, M., & Nabavi, S. M. (2016) · Food Chemistry · doi:10.1016/j.foodchem.2016.04.111 · Cited by 930 · see citing works
Meeran, M. F. N., Javed, H., Taee, H. A., Azimullah, S., & Ojha, S. K. (2017) · Frontiers in Pharmacology · doi:10.3389/fphar.2017.00380 · Cited by 622 · see citing works
Chemical Preservatives and Natural Antimicrobial Compounds
Davidson, P. M., Taylor, T. M., & Schmidt, S. E. (2014) · ASM Press eBooks · doi:10.1128/9781555818463.ch30 · Cited by 568 · see citing works
Natural Cinnamic Acids, Synthetic Derivatives and Hybrids with Antimicrobial Activity
Guzman, J. D. (2014) · Molecules · doi:10.3390/molecules191219292 · Cited by 419 · see citing works
Pei, R., Zhou, F. L., Ji, B., & Xu, J. (2009) · Journal of Food Science · doi:10.1111/j.1750-3841.2009.01287.x · Cited by 418 · see citing works
Espina, L., Somolinos, M., Lorán, S., Conchello, P., García‐Gonzalo, D., & Pagán, R. (2010) · Food Control · doi:10.1016/j.foodcont.2010.11.021 · Cited by 404 · see citing works
Use of natural antimicrobials to increase antibiotic susceptibility of drug resistant bacteria
Palaniappan, K., & Holley, R. A. (2010) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2010.04.001 · Cited by 355 · see citing works
Mith, H., Dure, R., Delcenserie, V., Zhiri, A., Daube, G., & Clinquart, A. (2014) · Food Science & Nutrition · doi:10.1002/fsn3.116 · Cited by 334 · see citing works
Jafarzadeh, S., Jafari, S. M., Salehabadi, A., Nafchi, A. M., Uthaya Kumar, U. S., & Khalil, H. P. S. A. (2020) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2020.04.017 · Cited by 288 · see citing works
Structural Requirements for the Antimicrobial Activity of Carvacrol
Veldhuizen, E. J. A., Bokhoven, J. L. M. T.-V., Zweijtzer, C., Burt, S. A., & Haagsman, H. P. (2006) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf052564y · Cited by 287 · see citing works
Lactic Acid Bacteria in Raw-Milk Cheeses: From Starter Cultures to Probiotic Functions
Coelho, M. C., Malcata, F. X., & Silva, C. C. G. (2022) · Foods · doi:10.3390/foods11152276 · Cited by 276 · see citing works
“Diacetyl has been shown to exert antifungal and antibacterial effects at low pH [167,168].”
Food Safety through Natural Antimicrobials
Quinto, E. J., Caro, I., Delgado, L. H. V., Mateo, J., Silleras, B. D. M., & Redondo-Del-Río, M. P. (2019) · Antibiotics · doi:10.3390/antibiotics8040208 · Cited by 251 · see citing works
Σολωμάκος, Ν., Govaris, A., Koidis, P., & Botsoglou, N. A. (2007) · Meat Science · doi:10.1016/j.meatsci.2007.11.014 · Cited by 239 · see citing works
The Use of Plant Antimicrobial Compounds for Food Preservation
Hintz, T., Matthews, K. K., & Di, R. (2015) · BioMed Research International · doi:10.1155/2015/246264 · Cited by 240 · see citing works
Organic Acids and Meat Preservation: A Review
Theron, M. M., & Lues, J. F. R. (2007) · Food Reviews International · doi:10.1080/87559120701224964 · Cited by 225 · see citing works
Burt, S. A., Vlielander, R., Haagsman, H. P., & Veldhuizen, E. J. A. (2005) · Journal of Food Protection · doi:10.4315/0362-028x-68.5.919 · Cited by 226 · see citing works
Umaraw, P., & Verma, A. K. (2015) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2014.986563 · Cited by 210 · see citing works
Morsy, M. K., Khalaf, H. H., Sharoba, A. M., El‐Tanahi, H. H., & Cutter, C. N. (2014) · Journal of Food Science · doi:10.1111/1750-3841.12400 · Cited by 195 · see citing works
Antibacterial and efflux pump inhibitors of thymol and carvacrol against food-borne pathogens
Miladi, H., Zmantar, T., Chaabouni, Y., Fedhila, K., Bakhrouf, A., Mahdouani, K., & Chaieb, K. (2016) · Microbial Pathogenesis · doi:10.1016/j.micpath.2016.08.008 · Cited by 189 · see citing works
Kuorwel, K. K., Cran, M. J., Sonneveld, K., Miltz, J. W., & Bigger, S. W. (2011) · Journal of Food Science · doi:10.1111/j.1750-3841.2011.02384.x · Cited by 181 · see citing works
Terjung, N., Loeffler, M., Gibis, M., Hinrichs, J., & Weiß, J. (2011) · Food & Function · doi:10.1039/c2fo10198j · Cited by 181 · see citing works
Carvacrol and its derivatives as antibacterial agents
Marinelli, L., Stefano, A. D., & Cacciatore, I. (2018) · Phytochemistry Reviews · doi:10.1007/s11101-018-9569-x · Cited by 182 · see citing works
From plants to antimicrobials: Natural products against bacterial membranes
Nourbakhsh, F., Lotfalizadeh, M., Badpeyma, M., Shakeri, A., & Soheili, V. (2021) · Phytotherapy Research · doi:10.1002/ptr.7275 · Cited by 184 · see citing works
López‐Mata, M. A., Ruíz‐Cruz, S., Silva-Beltrán, N. P., Ornelas‐Paz, J. D. J., Zamudio‐Flores, P. B., & Burruel-Ibarra, S. E. (2013) · Molecules · doi:10.3390/molecules181113735 · Cited by 148 · see citing works
The inhibitory effect of plant essential oils on foodborne pathogenic bacteria in food
Ju, J., Xie, Y., Guo, Y., Cheng, Y., Qian, H., & Yao, W. (2018) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2018.1488159 · Cited by 150 · see citing works
YEŞİLBAĞ, D., Eren, M., Agel, H. E., Kovanlıkaya, A., & Balcı, F. (2011) · British Poultry Science · doi:10.1080/00071668.2011.599026 · Cited by 136 · see citing works
Gutiérrez-Larraínzar, M., Rúa, J., Caro, I., de Castro, C., de Arriaga, D., García‐Armesto, M. R., & del Valle, P. (2012) · Food Control · doi:10.1016/j.foodcont.2012.02.025 · Cited by 134 · see citing works
Rurián-Henares, J. A., & Morales, F. J. (2008) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf073300+ · Cited by 132 · see citing works
Rivas, L., McDonnell, M. J., Burgess, C. M., O’Brien, M., Navarro‐Villa, A., Fanning, S., & Duffy, G. (2010) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2010.01.029 · Cited by 126 · see citing works
(2008) · Methods in molecular biology · doi:10.1007/978-1-59745-419-3 · Cited by 120 · see citing works
Miladi, H., Zmantar, T., Kouidhi, B., Chaabouni, Y., Mahdouani, K., Bakhrouf, A., & Chaieb, K. (2017) · Microbial Pathogenesis · doi:10.1016/j.micpath.2017.01.012 · Cited by 118 · see citing works
Ma, Q., Davidson, P. M., & Zhong, Q. (2013) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2013.06.017 · Cited by 115 · see citing works
Campylobacter and Arcobacter species sensitivity to commercial orange oil fractions
Nannapaneni, R., Chalova, V. I., Crandall, P. G., Ricke, S. C., Johnson, M. G., & O’Bryan, C. A. (2008) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2008.11.008 · Cited by 110 · see citing works
Bacteriocins from the rhizosphere microbiome – from an agriculture perspective
Subramanian, S., & Smith, D. L. (2015) · Frontiers in Plant Science · doi:10.3389/fpls.2015.00909 · Cited by 109 · see citing works
Innovative Active Packaging Systems to Prolong the Shelf Life of Mozzarella Cheese
Conte, A., Scrocco, C., Sinigaglia, M., & Nobile, M. A. D. (2007) · Journal of Dairy Science · doi:10.3168/jds.2006-709 · Cited by 105 · see citing works
Ravishankar, S., Zhu, L., Reyna-Granados, J. R., Law, B. F., Joens, L. A., & Friedman, M. (2010) · Journal of Food Protection · doi:10.4315/0362-028x-73.2.234 · Cited by 101 · see citing works
Yılmaz, S., Sova, M., & Ergün, S. (2018) · Journal of Applied Microbiology · doi:10.1111/jam.14097 · Cited by 98 · see citing works
A mini-review of Thymol incorporated materials: Applications in antibacterial wound dressing
Najafloo, R., Behyari, M., Imani, R., & Nour, S. (2020) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2020.101904 · Cited by 98 · see citing works
Pérez-Conesa, D., McLandsborough, L., & Weiss, J. (2006) · Journal of Food Protection · doi:10.4315/0362-028x-69.12.2947 · Cited by 95 · see citing works
Impact of plant derivatives on the growth of foodborne pathogens and the functionality of probiotics
Gyawali, R., & Ibrahim, S. A. (2012) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-012-4117-x · Cited by 90 · see citing works
Pichika, M. R., Mak, K., Kamal, M. B. B., Buru, A. S., Sakirolla, R., Kang, Y.-B., Mohandas, K., Balijepalli, M., & Ahmad, S. (2019) · Pharmacognosy Reviews/Bioinformatics Trends/Pharmacognosy review · doi:10.4103/phrev.phrev_46_18 · Cited by 89 · see citing works
Lahiri, D., Nag, M., Dutta, B., Dey, S., Mukherjee, D., Joshi, S. J., & Ray, R. R. (2021) · Journal of Applied Microbiology · doi:10.1111/jam.15171 · Cited by 87 · see citing works
A Study on the Antimicrobial Activity of Thymol Intended as a Natural Preservative
Falcone, P. M., Speranza, B., Nobile, M. A. D., Corbo, M. R., & Sinigaglia, M. (2005) · Journal of Food Protection · doi:10.4315/0362-028x-68.8.1664 · Cited by 87 · see citing works
Hayouni, E. A., Bouix, M., Abedrabba, M., Leveau, J.-Y., & Hamdi, M. (2008) · Food Chemistry · doi:10.1016/j.foodchem.2008.04.044 · Cited by 82 · see citing works
Influence of liposome encapsulated essential oils on properties of chitosan films
Valencia‐Sullca, C., Jiménez, M., Jiménez, A., Atarés, L., Vargas, M., & Chiralt, A. (2016) · Polymer International · doi:10.1002/pi.5143 · Cited by 80 · see citing works
Campion, A., Morrissey, R., Field, D., Cotter, P. D., Hill, C., & Ross, R. P. (2017) · Food Microbiology · doi:10.1016/j.fm.2017.01.020 · Cited by 80 · see citing works
Benali, T., Habbadi, K., Khabbach, A., Marmouzi, I., Zengin, G., Bouyahya, A., Chamkhi, I., Chtibi, H., Aanniz, T., Achbani, E. H., et al. (2020) · Foods · doi:10.3390/foods9050668 · Cited by 80 · see citing works
Michiels, J., Missotten, J., Fremaut, D., SMET, S. D., & Dierick, N. A. (2009) · Animal Feed Science and Technology · doi:10.1016/j.anifeedsci.2009.01.004 · Cited by 77 · see citing works
Chen, F.-P., Kong, N.-Q., Wang, L., Luo, Z. L., Yin, J., & Chen, Y. (2020) · Food Chemistry · doi:10.1016/j.foodchem.2020.127594 · Cited by 76 · see citing works
Khalaf, H., Sharoba, A. M., El‐Tanahi, H. H., & Morsy, M. K. (2013) · Journal of Food and Dairy Sciences · doi:10.21608/jfds.2013.72104 · Cited by 75 · see citing works
Quality Parameters and Antioxidant and Antibacterial Properties of Some Mexican Honeys
Rodríguez, B. A., Mendoza, S., Hernández‐Iturriaga, M., & Castaño‐Tostado, E. (2011) · Journal of Food Science · doi:10.1111/j.1750-3841.2011.02487.x · Cited by 74 · see citing works
Antimicrobial Activities of Single Aroma Compounds
Schmidt, E., Bail, S., Friedl, S. M., Jirovetz, L., Buchbauer, G., Wanner, J., Denkova, Z. R., Slavchev, A., Stoyanova, A., & Geißler, M. (2010) · Natural Product Communications · doi:10.1177/1934578x1000500906 · Cited by 73 · see citing works
Physicochemical and antimicrobial properties of cassava starch films with ferulic or cinnamic acid
Ordoñez, R., Atarés, L., & Chiralt, A. (2021) · LWT · doi:10.1016/j.lwt.2021.111242 · Cited by 72 · see citing works
Gomez-Sequeda, N., Cáceres, M., Stashenko, E. E., Hidalgo, W., & Ortíz, C. (2020) · Antibiotics · doi:10.3390/antibiotics9110730 · Cited by 75 · see citing works
Quintana, S. E., Llalla-Córdova, O., García‐Risco, M. R., & Fornari, T. (2021) · The Journal of Supercritical Fluids · doi:10.1016/j.supflu.2021.105198 · Cited by 69 · see citing works
Bacterial nanocellulose membranes combined with nisin: a strategy to prevent microbial growth
dos Santos, C. A., dos Santos, G. R., Soeiro, V. S., dos Santos, J. R., Rebelo, M. D. A., Chaud, M. V., Gerenutti, M., Grotto, D., Pandit, R., Rai, M., et al. (2018) · Cellulose · doi:10.1007/s10570-018-2010-1 · Cited by 66 · see citing works
Moore-Neibel, K., Gerber, C. W., Patel, J., Friedman, M., Jaroni, D., & Ravishankar, S. (2012) · Food Microbiology · doi:10.1016/j.fm.2012.12.001 · Cited by 61 · see citing works
Araújo, M. K., Gumiela, A. M., Bordin, K., Luciano, F. B., & de Macedo, R. E. F. (2018) · Meat Science · doi:10.1016/j.meatsci.2018.05.002 · Cited by 61 · see citing works
Huang, Z., Pang, D., Liao, S., Zou, Y., Zhou, P., Li, E., & Wang, W. (2021) · Industrial Crops and Products · doi:10.1016/j.indcrop.2021.113296 · Cited by 60 · see citing works
Jakubska, A. (2005) · Applied Ecology and Environmental Research · doi:10.15666/aeer/0302_029038 · Cited by 60 · see citing works
Gutiérrez-Pacheco, M. M., González-Aguilar, G. A., Martínez‐Téllez, M. Á., Lizardi‐Mendoza, J., Madera-Santana, T. J., Bernal-Mercado, A. T., Vázquez-Armenta, F. J., & Ayala-Zavala, J. F. (2018) · Food Control · doi:10.1016/j.foodcont.2018.02.007 · Cited by 61 · see citing works
Effects of Common Forage Phenolic Acids on Escherichia coli O157:H7 Viability in Bovine Feces
Wells, J. E., Berry, E. D., & Varel, V. H. (2005) · Applied and Environmental Microbiology · doi:10.1128/aem.71.12.7974-7979.2005 · Cited by 58 · see citing works
Jahdkaran, E., Hosseini, S. E., Nafchi, A. M., & Nouri, L. (2021) · Food Science & Nutrition · doi:10.1002/fsn3.2240 · Cited by 56 · see citing works
Antibacterial activity of pullulan films containing thymol
Gniewosz, M., & Synowiec, A. (2011) · Flavour and Fragrance Journal · doi:10.1002/ffj.2063 · Cited by 56 · see citing works
Gastrointestinal Absorption and Urinary Excretion of trans-Cinnamic and p-Coumaric Acids in Rats
Garrait, G., Jarrige, J.-F., Blanquet, S., Beyssac, E., Cardot, J., & Alric, M. (2006) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf053169a · Cited by 54 · see citing works
Langa, S., Martín‐Cabrejas, I., Montiel, R., Landete, J. M., Médina, M., & Arqués, J. L. (2014) · Journal of Dairy Science · doi:10.3168/jds.2014-8306 · Cited by 53 · see citing works
Sánchez-Gómez, S., Lamata, M., Leiva, J., Blondelle, S. E., Jerala, R., Andrä, J., Brandenburg, K., Lohner, K., Moriyón, I., & de Tejada, G. M. (2008) · BMC Microbiology · doi:10.1186/1471-2180-8-196 · Cited by 50 · see citing works
Lee, S.-Y., & Jin, H.-H. (2008) · Letters in Applied Microbiology · doi:10.1111/j.1472-765x.2008.02432.x · Cited by 51 · see citing works
Nisin A and Polymyxin B as Synergistic Inhibitors of Gram-positive and Gram-negative Bacteria
Naghmouchi, K., Drider, D., Baah, J., & Teather, R. M. (2010) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-009-9033-8 · Cited by 50 · see citing works
da Silva, R. S., de Oliveira, M. M. G., de Melo, J. O., Blank, A. F., Corrêa, C. B., Scher, R., & Fernandes, R. P. M. (2019) · Pesticide Biochemistry and Physiology · doi:10.1016/j.pestbp.2019.06.014 · Cited by 50 · see citing works
The beneficial role of plant based thymol in food packaging application: A comprehensive review
Sivaram, S., Somanathan, H., Kumaresan, S. M., & Sundaram, M. (2022) · Applied Food Research · doi:10.1016/j.afres.2022.100214 · Cited by 49 · see citing works
Analysis of the essential oil components from different Carum copticumL. samples from Iran
Zarshenas, M. M., Samani, S. M., Petramfar, P., & Moein, M. (2013) · Pharmacognosy Research · doi:10.4103/0974-8490.122920 · Cited by 49 · see citing works
Paomephan, P., Assavanig, A., Chaturongakul, S., Cady, N. C., Bergkvist, M., & Niamsiri, N. (2017) · Food Control · doi:10.1016/j.foodcont.2017.09.021 · Cited by 48 · see citing works
Short Linear Cationic Antimicrobial Peptides: Screening, Optimizing, and Prediction
Hilpert, K., Fjell, C. D., & Cherkasov, A. R. (2008) · Methods in molecular biology · doi:10.1007/978-1-59745-419-3_8 · Cited by 46 · see citing works
Wang, X., Hu, Y., Zhang, Z., & Zhang, B. (2021) · Journal of Cultural Heritage · doi:10.1016/j.culher.2021.12.002 · Cited by 46 · see citing works
Liolios, C. C., Laouer, H., Boulaacheb, N., Gortzi, O., & Chinou, İ. (2007) · Molecules · doi:10.3390/12040772 · Cited by 46 · see citing works
Bacon, K., Boyer, R. R., Denbow, C. J., O’Keefe, S. F., Neilson, A. P., & Williams, R. C. (2017) · Food Science & Nutrition · doi:10.1002/fsn3.453 · Cited by 45 · see citing works
Otto, M., Wynands, B., Lenzen, C., Filbig, M., Blank, L. M., & Wierckx, N. J. P. (2019) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2019.00312 · Cited by 45 · see citing works
Plants: A natural solution to enhance raw milk cheese preservation?
Dupas, C., Métoyer, B., El‐Hatmi, H., Adt, I., Mahgoub, S. A., & Dumas, E. (2019) · Food Research International · doi:10.1016/j.foodres.2019.108883 · Cited by 45 · see citing works
Untangling the bioactive properties of therapeutic deep eutectic solvents based on natural terpenes
Silva, E., Oliveira, F., Silva, J. M., Reis, R. L., & Duarte, A. R. C. (2021) · Current Research in Chemical Biology · doi:10.1016/j.crchbi.2021.100003 · Cited by 44 · see citing works
Zhang, D., Hu, H., Rao, Q., & Zhao, Z. (2011) · Foodborne Pathogens and Disease · doi:10.1089/fpd.2010.0817 · Cited by 43 · see citing works
Panahi, Z., & Mohsenzadeh, M. (2022) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2022.109883 · Cited by 42 · see citing works
Thymol Disrupts Cell Homeostasis and Inhibits the Growth of Staphylococcus aureus
Li, Q., Huang, K. X., Pan, S., Su, C., Bi, J., & Lu, X. (2022) · Contrast Media & Molecular Imaging · doi:10.1155/2022/8743096 · Cited by 41 · see citing works
Yun, J., Fan, X., & Li, X. (2013) · Journal of Food Science · doi:10.1111/1750-3841.12052 · Cited by 40 · see citing works
Bouyahya, A., Guaouguaou, F., Dakka, N., & Bakri, Y. (2017) · Asian Pacific Journal of Tropical Disease · doi:10.12980/apjtd.7.2017d7-31 · Cited by 39 · see citing works
ANTIMICROBIALS USED IN ACTIVE PACKAGING FILMS
Dıblan, S., & Kaya, S. (2018) · Food and Health · doi:10.3153/jfhs18007 · Cited by 39 · see citing works
Antibacterial Activities of Thymol, Eugenol and Nisin Against Some Food Spoilage Bacteria
Tippayatum, P., & Chonhenchob, V. (2007) · Agriculture and Natural Resources · Cited by 38 · see citing works
Antibacterial activity of essential oils: potential applications in food
Burt, S. A. (2002) · Utrecht University Repository (Utrecht University) · Cited by 38 · see citing works
The Herbal Compound Thymol Protects Mice From Lethal Infection by Salmonella Typhimurium
Zhang, Y., Liu, Y., Qiu, J., Luo, Z., & Deng, X. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.01022 · Cited by 37 · see citing works
Knight, K. P., & McKellar, R. C. (2007) · Journal of Food Protection · doi:10.4315/0362-028x-70.9.2089 · Cited by 37 · see citing works
The inhibitory effect of natural bioactives on the growth of pathogenic bacteria
Kim, J., & Kim, Y. (2007) · Nutrition Research and Practice · doi:10.4162/nrp.2007.1.4.273 · Cited by 36 · see citing works
Berard, N., Holley, R. A., McAllister, T. A., Ominski, K., Wittenberg, K. M., Bouchard, K. S., Bouchard, J. J., & Krause, D. O. (2008) · Applied and Environmental Microbiology · doi:10.1128/aem.00983-08 · Cited by 36 · see citing works
de la Fuente‐Salcido, N. M., Alanís-Guzmán, M. G., Bideshi, D. K., Salcedo‐Hernández, R., Justo, M. B., & Barboza-Corona, J. E. (2008) · Archives of Microbiology · doi:10.1007/s00203-008-0414-2 · Cited by 36 · see citing works
Jung, K., Chung, M., Bai, H., Chung, B.-Y., & Lee, S. (2021) · Molecules · doi:10.3390/molecules26113476 · Cited by 36 · see citing works
Mohsen, A. M., Nagy, Y. I., Shehabeldine, A. M., & Okba, M. M. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics15010019 · Cited by 35 · see citing works
Antimicrobial Activity of Natural Agents Coated on Starch‐Based Films against Staphylococcus aureus
Kuorwel, K. K., Cran, M. J., Sonneveld, K., Miltz, J. W., & Bigger, S. W. (2011) · Journal of Food Science · doi:10.1111/j.1750-3841.2011.02344.x · Cited by 35 · see citing works
Antibacterial activities of plant-derived compounds and essential oils against Cronobacter strains
Berthold‐Pluta, A., Stasiak-Różańska, L., Pluta, A., & Garbowska, M. (2018) · European Food Research and Technology · doi:10.1007/s00217-018-3218-x · Cited by 35 · see citing works
Loo, E. J. V., Babu, D., Crandall, P. G., & Ricke, S. C. (2012) · Journal of Food Protection · doi:10.4315/0362-028x.jfp-11-543 · Cited by 35 · see citing works
Felicioli, A., Cilia, G., Mancini, S., Turchi, B., Galaverna, G., Cirlini, M., Cerri, D., & Fratini, F. (2019) · Food Bioscience · doi:10.1016/j.fbio.2019.04.004 · Cited by 33 · see citing works
Ma, M., Zhao, J., Zeng, Z., Wan, D., Yu, P., Cheng, D., Gong, D., & Deng, S. (2020) · LWT · doi:10.1016/j.lwt.2020.109794 · Cited by 32 · see citing works
- Authors
- Olasupo, N. A., Fitzgerald, D. J., Gasson, M. J., & Narbad, A.
- Affiliations
- Lagos State University (NG)
- Norwich Research Park (GB)
- Corresponding author
- Narbad, A.
- Venue
- Letters in Applied Microbiology
- Publisher
- Oxford University Press (OUP)
- Published
- 2003-12
- Volume
- 37
- Issue
- 6
- Pages
- 448-451
- ISSN
- 0266-8254 (ISSN-L)
- 1365-2673
- OpenAlex
- W1970033253
- Cited by
- 218
- References
- 22
- Citations by year
- 2026: 2 · 2025: 5 · 2024: 4 · 2023: 7 · 2022: 11 · 2021: 19 · 2020: 11 · 2019: 12 · 2018: 16 · 2017: 13 · 2016: 8 · 2015: 9 · 2014: 10 · 2013: 12 · 2012: 12
- FWCI
- 4.35
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Letters in Applied Microbiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
- Physical Sciences › Chemistry › Organic Chemistry › Antimicrobial agents and applications
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Keywords
- natural antimicrobials, Escherichia coli, Salmonella typhimurium, nisin, thymol, carvacrol, eugenol, cinnamic acid, diacetyl, minimum inhibitory concentration, synergistic and antagonistic effects, Gram-negative bacteria, food safety
- MeSH terms
- Cymenes, Anti-Bacterial Agents, Cinnamates, Diacetyl, Drug Therapy, Combination, Escherichia coli, Eugenol, Microbial Sensitivity Tests, Nisin, Salmonella typhimurium, Thymol, Monoterpenes, In Vitro Techniques
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
