The DOI matches its Crossref record; 131 of the 132 references it cites were found in a registry or an index.
Fifty Years of Skin Aging
Open accessAbstract
In developed countries, interest in cutaneous aging is in large part the result of a progressive, dramatic rise over the past century in the absolute number and the proportion of the population who are elderly (Smith et al, 2001). The psychosocial as well as physiologic effects of skin aging on older individuals have created a demand for better understanding of the process and particularly for effective interventions. Skin aging is a complex process determined by the genetic endowment of the individual as well as by environmental factors. The appearance of old skin and the clinical consequences of skin aging have been well known for centuries, but only in the past 50 y have mechanisms and mediators been systematically pursued. Still, within this relatively short time there has been tremendous progress, a progress greatly enhanced by basic gerontologic research employing immunologic, biochemical, and particularly molecular biologic approaches (Figs 1, 2).
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“Extrinsically aged skin is characterised by deep wrinkles, rough texture, telengiectasia and irregular pigmentation [4].”
From Oxidative Stress and Ageing: The Influence of Environmental Pollution, Sunlight and Diet on Skin (2017) · cites this paper as [4]
Citations
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Items 201–232 of 232
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Metadata
- Authors
- Yaar, M., Eller, M. S., & Gilchrest, B. A.
- Affiliations
- Boston University (US)
- Corresponding author
- Gilchrest, Barbara A.
- Venue
- Journal of Investigative Dermatology Symposium Proceedings
- Publisher
- Elsevier BV
- Published
- 2002-12
- Volume
- 7
- Issue
- 1
- Pages
- 51-58
- ISSN
- 1087-0024 (ISSN-L)
- OpenAlex
- W2000936610
- Cited by
- 233
- References
- 132
- Citations by year
- 2026: 5 · 2025: 5 · 2024: 8 · 2023: 14 · 2022: 10 · 2021: 11 · 2020: 15 · 2019: 17 · 2018: 12 · 2017: 14 · 2016: 27 · 2015: 10 · 2014: 11 · 2013: 8 · 2012: 10
- FWCI
- 21.57
- Type
- conference paper
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of Investigative Dermatology Symposium Proceedings (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Dermatology › Skin Protection and Aging
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Aging › Genetics, Aging, and Longevity in Model Organisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Telomeres, Telomerase, and Senescence
- Keywords
- skin aging, aging mechanisms, genetic factors, environmental factors, older adults, aging interventions
- MeSH terms
- Animals, Dermatology, Humans, Skin Physiological Phenomena, Skin Aging, Gene Expression, Telomere, Oxidative Stress
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