The DOI matches its Crossref record; 128 of the 129 references it cites were found in a registry or an index.
The Commensal Microbiota and Enteropathogens in the Pathogenesis of Inflammatory Bowel Diseases
Open accessAbstract
Intestinal inflammation arises from abnormal host-microbe interactions. The perturbations of homeostatic coexistence involve host genetic factors, barrier function, innate and adaptive immunity, as well as qualitative and quantitative changes in the composition of the microbiota. Dysbiosis toward selected micro-organisms and decreased complexity of commensal bacteria have been observed in patients with Crohn's disease and ulcerative colitis, but it is not clear whether the dysbiosis contributes to development of inflammatory bowel disease or is instead a consequence of the disease. Pathogens with virulence factors that allow them to breach the intestinal barrier and induce chronic inflammation might mediate the pathogenesis of these diseases. To identify new therapeutic approaches for inflammatory bowel disease, it is important to identify host susceptibility factors involved in the control of microbial infection, characterize potential pathogens, and eliminate them or block the expression of their virulence factors.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“There is a decreased complexity in composition, with a loss of normal anaerobic bacteria [33] , a temporary composition instability during clinical remission [34] , and a dysbiosis towards selected microorganisms, with over-and under-representation of certain species [35] .”
From Intestinal microbiota in health and disease: Role of bifidobacteria in gut homeostasis (2014) · cites this paper as [35]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
A human gut microbial gene catalogue established by metagenomic sequencing
MetaHIT Consortium, Qin, J., Li, R., Raes, J., Arumugam, M., Burgdorf, K. S., Manichanh, C., Nielsen, T., Pons, N., Levenez, F., et al. (2010) · Nature · doi:10.1038/nature08821 · Cited by 11,624
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
The Wellcome Trust Case Control Consortium, Management Committee, Burton, P. R., Clayton, D. G., Cardon, L. R., Craddock, N., Deloukas, P., Duncanson, A., Kwiatkowski, D. P., McCarthy, M. I., et al. (2007) · Nature · doi:10.1038/nature05911 · Cited by 9,442
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
Hugot, J.-P., Chamaillard, M., Zouali, H., Lesage, S., Cézard, J.-P., Belaiche, J., Almer, S., Tysk, C., O'Morain, C. A., Gassull, M., et al. (2001) · Nature · doi:10.1038/35079107 · Cited by 5,591
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
Ogura, Y., Bonen, D. K., Inohara, N., Nicolae, D. L., Chen, F. F., Ramos, R., Britton, H., Moran, T., Karaliuskas, R., Duerr, R. H., et al. (2001) · Nature · doi:10.1038/35079114 · Cited by 5,030
Korn, T., Bettelli, E., Oukka, M., & Kuchroo, V. K. (2009) · Annual Review of Immunology · doi:10.1146/annurev.immunol.021908.132710 · Cited by 4,873
Metagenomic Analysis of the Human Distal Gut Microbiome
Gill, S. R., Pop, M., DeBoy, R. T., Eckburg, P. B., Turnbaugh, P. J., Samuel, B. S., Gordon, J. I., Relman, D. A., Fraser-Liggett, C. M., & Nelson, K. E. (2006) · Science · doi:10.1126/science.1124234 · Cited by 4,699
Frank, D. N., St. Amand, A. L., Feldman, R. A., Boedeker, E. C., Harpaz, N., & Pace, N. R. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0706625104 · Cited by 4,611
Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria
Ivanov, I. I., Atarashi, K., Manel, N., Brodie, E. L., Shima, T., Karaoz, U., Wei, D., Goldfarb, K. C., Santee, C. A., Lynch, S. V., et al. (2009) · Cell · doi:10.1016/j.cell.2009.09.033 · Cited by 4,554
Sokol, H., Pigneur, B., Watterlot, L., Lakhdari, O., Bermúdez-Humarán, L. G., Gratadoux, J.-J., Blugeon, S., Bridonneau, C., Furet, J.-P., Corthier, G., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0804812105 · Cited by 4,413
Unravelling the pathogenesis of inflammatory bowel disease
Xavier, R. J., & Podolsky, D. K. (2007) · Nature · doi:10.1038/nature06005 · Cited by 4,364
Flagged first, then by citations
1 of the 129 references couldn’t be matched to a known paper.
Research works printed but not linked: 1
- Garrett, 2007, Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system, Cell, 131, 33, 10.1016/j.cell.2007.08.017 · DOI
Cited by
Sorted by citations
Items 401–443 of 443
Rolhion, N., & Darfeuille–Michaud, A. (2013) · Heat shock proteins · doi:10.1007/978-94-007-6787-4_22
Self-citationImplication de la flore fongique intestinale dans le développement de la maladie
Colombel, J., Poulain, D., & Sendid, B. (2013)
Harnessing the Power of Posttranscriptional Gene Silencing in Crohn's Disease
Abdalla, M., & Sheikh, S. Z. (2016) · Clinical and Translational Gastroenterology · doi:10.1038/ctg.2016.5
IMAGING AND ADVANCED TECHNOLOGY
Kießlich, R., Wang, T. D., Moon, J. H., Terheggen, G., Choi, H. J., & Neuhaus, H. (2011)
The role of mesenchymal stromal cells in the treatment of ulcerative colitis and C rohn's disease
Grégoire, C., Lechanteur, C., Briquet, A., Baudoux, É., Giet, O., Delloye, O., Baron, F., Louis, E. J., & Beguin, Y. P. (2016) · doi:10.1002/9781118907474.ch50
RegIII proteins as gatekeepers of the intestinal epithelium
Loonen, L. M. P. (2013) · doi:10.18174/273681
Study of PepT1 and SPAK on Intestinal Homeostasis and Intestinal Inflammation
Zhang, Y. (2022) · Digital Archive @ GSU · doi:10.57709/9399989
Nutrition therapy for active Crohn's disease
Wall, C. L. (2017) · Otago University Research Archive (University of Otago)
Changes in Weight Status and the Intestinal Microbiota among College Students
Journey, E. (2017) · Arizona State University Library Digital Repository (Arizona State University)
Microbes in Colon Cancer and Inflammatory Bowel Disease
Fong, I. W. (2014) · Springer eBooks · doi:10.1007/978-1-4939-1670-2_2
Culpepper, C. D. (2022) · Digital Archive @ GSU · doi:10.57709/13394582
Who Inhabits Our Gut? Introducing the Human Gut Microbiota
Flint, H. J. (2020) · Fascinating life sciences · doi:10.1007/978-3-030-43246-1_5
Human Gut Microbiota: Friend or Foe?
Pliszka, M., & Szablewski, L. (2020) · OBM Hepatology and Gastroenterology · doi:10.21926/obm.hg.2003050
Vers un vaccin contre les maladies inflammatoires chroniques ?
Naimi, S., & Chassaing, B. (2020) · médecine/sciences · doi:10.1051/medsci/2020137
Self-citationCrohn’s disease: between the genetic determinism and the epigenetic hope
Faculté de Médecine, U. H. L., & Belaaloui, G. (2015) · Batna Journal of Medical Sciences (BJMS) · doi:10.48087/bjmstf.2015.2111
Dutta, A., Datta, S., & Snehlata, S. (2021) · Elsevier eBooks · doi:10.1016/b978-0-323-85652-2.00011-7
Vandenplas, Y., Huys, G. R. B., & Daube, G. (2015) · Springer eBooks · doi:10.1007/978-3-319-17169-2_45
Hornef, M. W. (2018) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.733879009.793551960
Shao, M., Luo, H., Liu, J., Yuan, F., & Deng, Y. (2022) · Research Square · doi:10.21203/rs.3.rs-1457841/v1
Shi, Y., Shi, Y., Huang, C., Gong, P.-Q., Liu, C., Hu, Z.-Q., & Wang, H. (2022) · SSRN Electronic Journal · doi:10.2139/ssrn.4071636
Schiffrin, E. J., Marteau, P. R., & Brassart, D. (2014) · CRC Press eBooks · doi:10.1201/b16442-10
Wade, A. J. H. (2014) · Otago University Research Archive (University of Otago)
Microorganisms in the Pathogenesis and Management of Crohn’s Disease (CD)
Shah, F., & Dwivedi, M. (2022) · Springer eBooks · doi:10.1007/978-981-19-4800-8_13
St-Laurent, T. (2022) · University of Ottawa Journal of Medicine · doi:10.18192/uojm.v13i01.6149
Saghari, M., Gal, P., Grievink, H. W., Klaassen, E. S., Zhuparris, A., Itano, A. A., Bodmer, M., McHale, D., & Moerland, M. (2023) · Medicine in Microecology · doi:10.1016/j.medmic.2023.100088
An Insight to Block Copolymers in Inflammatory Bowel Disease Management
Garg, A., Ashique, S., Kumar, S., Soni, M. L., Shravastava, A., Pandey, V., Garud, N., Agrawal, A., Akram, W., & Mishra, N. (2023) · Springer eBooks · doi:10.1007/978-981-99-6917-3_9
Nurturing Gut Health: Exploring Prebiotics and Probiotics for Gastrointestinal Wellness
Gali, S. P., Reshma, R. G., Harini, A., & Meenatchi, R. (2024) · Springer eBooks · doi:10.1007/978-3-031-72757-3_22
Yan, C., Huang, S.-H., Ding, H., He, W., Zhu, H., & Chen, Z. (2024) · Journal of Food Bioactives · doi:10.26599/jfb.2024.95028391
Tree-extracted mucilages: Arabinogalactan
Li, S., & Tan, H. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-21630-5.00007-1
Duquesnoy, M., Peyrin‐Biroulet, L., Viennois, É., & Chassaing, B. (2025) · Bulletin de l Académie Nationale de Médecine · doi:10.1016/j.banm.2025.01.001
Self-citationAdditional file 2 of Direct impact of commonly used dietary emulsifiers on human gut microbiota
Naimi, S., Viennois, É., Gewirtz, A. T., & Chassaing, B. (2021) · Figshare · doi:10.6084/m9.figshare.14267040
Self-citationAnalysis of the use of monoclonal antibodies in the treatment of Crohn’s disease
Blagov, A. V., Sazonova, M. D., Ryzhkova, A., Карагодин, В. П., Popov, M. A., Budnikov, E. Y., Ravani, A. L., Orekhov, A. N., Sazonova, M. A., & Arkhipenko, Y. V. (2026) · Antibody Therapeutics · doi:10.1093/abt/tbag006
Ahmad, I. A. (2013) · theses.fr (ABES) · doi:10.70675/ea74a5feze54bz4494z8911z80bf7424757a
Comparative Genomics of Faecalibacterium spp.
Benevides, L. (2018) · theses.fr (ABES) · doi:10.70675/48a456b7zbca1z4bbez86fdz1d28c0c4b936
Etude de la perméabilité intestinale au cours de l'obésité humaine
Genser, L. (2017) · theses.fr (ABES) · doi:10.70675/b31dde1bz1941z4398zaa56z406e97d709fa
Rôle de l'îlot génomique pks dans la synthèse des sidérophores-microcines chez Escherichia coli
Massip, C. (2019) · theses.fr (ABES) · doi:10.70675/79fd3cdcz6be0z491ez95c5zf2b155b65e97
Son, S. J., Han, A., Sung, M. J., Na, H., Hong, S. M., & Lee, S. H. (2026) · Food Science & Nutrition · doi:10.1002/fsn3.71763
Rytter, H., Chevarin, C., Martin, L., Bruder, E., Denizot, J., Tenaillon, O., Espéli, O., Birer, A., Barnich, N., Viennois, É., et al. (2026) · Journal of Crohn s and Colitis · doi:10.1093/ecco-jcc/jjag088
Self-citationTan, D., Lou, Y., Chen, W., Wang, Q., Bai, W., & Tian, L. (2026) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.6c08347
HOPX EXPRESSION IN IMMUNE REGULATORY B CELL REGULATE INTESTINAL INFLAMMATION
Thayaparana, N. (2012) · MacSphere (McMaster University) · doi:10.71548/19830
Metadata
- Authors
- Chassaing, B., & Darfeuille–Michaud, A.
- Affiliations
- Université Clermont Auvergne (FR)
- Corresponding author
- Darfeuille–Michaud, Arlette
- Venue
- Gastroenterology
- Publisher
- Elsevier BV
- Published
- 2011-05
- Volume
- 140
- Issue
- 6
- Pages
- 1720-1728.e3
- ISSN
- 0016-5085 (ISSN-L)
- OpenAlex
- W2061275484
- Cited by
- 443
- References
- 129
- Citations by year
- 2026: 6 · 2025: 14 · 2024: 18 · 2023: 22 · 2022: 24 · 2021: 24 · 2020: 30 · 2019: 22 · 2018: 41 · 2017: 27 · 2016: 45 · 2015: 35 · 2014: 50 · 2013: 42 · 2012: 32
- FWCI
- 17.60
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Gastroenterology (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- Funders
- European Commission
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Health Sciences › Medicine › Gastroenterology › Inflammatory Bowel Disease
- Health Sciences › Medicine › Gastroenterology › Microscopic Colitis
- Keywords
- inflammatory bowel disease, Crohn's disease, ulcerative colitis, commensal microbiota, dysbiosis, enteric pathogens, host-microbe interactions, intestinal barrier function, virulence factors, host susceptibility, gut microbiota
- MeSH terms
- Animals, Bacterial Infections, Colitis, Ulcerative, Crohn Disease, Humans, Intestines, Paratuberculosis, Mycobacterium avium subsp. paratuberculosis, Genetic Predisposition to Disease
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
