Cited by 443Gut microbiota and healthInflammatory Bowel DiseaseMicroscopic Colitis

The DOI matches its Crossref record; 128 of the 129 references it cites were found in a registry or an index.

The Commensal Microbiota and Enteropathogens in the Pathogenesis of Inflammatory Bowel Diseases

Open access

Chassaing, Benoit, Darfeuille–Michaud, Arlette·2011·Gastroenterology

DOI 10.1053/j.gastro.2011.01.054

Open this paper in CoChat — free account Open PDF

Abstract

Intestinal inflammation arises from abnormal host-microbe interactions. The perturbations of homeostatic coexistence involve host genetic factors, barrier function, innate and adaptive immunity, as well as qualitative and quantitative changes in the composition of the microbiota. Dysbiosis toward selected micro-organisms and decreased complexity of commensal bacteria have been observed in patients with Crohn's disease and ulcerative colitis, but it is not clear whether the dysbiosis contributes to development of inflammatory bowel disease or is instead a consequence of the disease. Pathogens with virulence factors that allow them to breach the intestinal barrier and induce chronic inflammation might mediate the pathogenesis of these diseases. To identify new therapeutic approaches for inflammatory bowel disease, it is important to identify host susceptibility factors involved in the control of microbial infection, characterize potential pathogens, and eliminate them or block the expression of their virulence factors.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1053/j.gastro.2011.01.054

Cites

128 of 128 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

A human gut microbial gene catalogue established by metagenomic sequencing
MetaHIT Consortium, Qin, J., Li, R., Raes, J., Arumugam, M., Burgdorf, K. S., Manichanh, C., Nielsen, T., Pons, N., Levenez, F., et al. (2010) · Nature · doi:10.1038/nature08821 · Cited by 11,624
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
The Wellcome Trust Case Control Consortium, Management Committee, Burton, P. R., Clayton, D. G., Cardon, L. R., Craddock, N., Deloukas, P., Duncanson, A., Kwiatkowski, D. P., McCarthy, M. I., et al. (2007) · Nature · doi:10.1038/nature05911 · Cited by 9,442
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
Hugot, J.-P., Chamaillard, M., Zouali, H., Lesage, S., Cézard, J.-P., Belaiche, J., Almer, S., Tysk, C., O'Morain, C. A., Gassull, M., et al. (2001) · Nature · doi:10.1038/35079107 · Cited by 5,591
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
Ogura, Y., Bonen, D. K., Inohara, N., Nicolae, D. L., Chen, F. F., Ramos, R., Britton, H., Moran, T., Karaliuskas, R., Duerr, R. H., et al. (2001) · Nature · doi:10.1038/35079114 · Cited by 5,030
IL-17 and th17 cells
Korn, T., Bettelli, E., Oukka, M., & Kuchroo, V. K. (2009) · Annual Review of Immunology · doi:10.1146/annurev.immunol.021908.132710 · Cited by 4,873
Metagenomic Analysis of the Human Distal Gut Microbiome
Gill, S. R., Pop, M., DeBoy, R. T., Eckburg, P. B., Turnbaugh, P. J., Samuel, B. S., Gordon, J. I., Relman, D. A., Fraser-Liggett, C. M., & Nelson, K. E. (2006) · Science · doi:10.1126/science.1124234 · Cited by 4,699
Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases
Frank, D. N., St. Amand, A. L., Feldman, R. A., Boedeker, E. C., Harpaz, N., & Pace, N. R. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0706625104 · Cited by 4,611
Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria
Ivanov, I. I., Atarashi, K., Manel, N., Brodie, E. L., Shima, T., Karaoz, U., Wei, D., Goldfarb, K. C., Santee, C. A., Lynch, S. V., et al. (2009) · Cell · doi:10.1016/j.cell.2009.09.033 · Cited by 4,554
Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients
Sokol, H., Pigneur, B., Watterlot, L., Lakhdari, O., Bermúdez-Humarán, L. G., Gratadoux, J.-J., Blugeon, S., Bridonneau, C., Furet, J.-P., Corthier, G., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0804812105 · Cited by 4,413
Unravelling the pathogenesis of inflammatory bowel disease
Xavier, R. J., & Podolsky, D. K. (2007) · Nature · doi:10.1038/nature06005 · Cited by 4,364

Flagged first, then by citations

Show all 129 references

1 of the 129 references couldn’t be matched to a known paper.

Research works printed but not linked: 1

Garrett, 2007, Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system, Cell, 131, 33, 10.1016/j.cell.2007.08.017 · DOI

Sorted by citations

Dextran Sulfate Sodium (DSS)‐Induced Colitis in Mice
Chassaing, B., Aitken, J. D., Malleshappa, M., & Vijay–Kumar, M. (2014) · Current Protocols in Immunology · doi:10.1002/0471142735.im1525s104 · Cited by 2,094
Self-citation
A decrease of the butyrate-producing species Roseburia hominis and Faecalibacterium prausnitzii defines dysbiosis in patients with ulcerative colitis
Machiels, K., Joossens, M., Sabino, J., De Preter, V., Arijs, I., Eeckhaut, V., Ballet, V., Claes, K., Van Immerseel, F., Verbeke, K., et al. (2014) · Gut · doi:10.1136/gutjnl-2013-304833 · Cited by 1,904
The Microbiome in Inflammatory Bowel Disease: Current Status and the Future Ahead
Kostic, A. D., Xavier, R. J., & Gevers, D. (2014) · Gastroenterology · doi:10.1053/j.gastro.2014.02.009 · Cited by 1,789
The keystone-pathogen hypothesis
Hajishengallis, G., Darveau, R. P., & Curtis, M. A. (2012) · Nature Reviews Microbiology · doi:10.1038/nrmicro2873 · Cited by 1,790
Intestinal permeability – a new target for disease prevention and therapy
Bischoff, S. C., Barbara, G., Buurman, W., Ockhuizen, T., Schulzke, J.-D., Serino, M., Tilg, H., Watson, A., & Wells, J. M. (2014) · BMC Gastroenterology · doi:10.1186/s12876-014-0189-7 · Cited by 1,755
Regional specialization within the intestinal immune system
Mowat, A. M., & Agace, W. W. (2014) · Nature reviews. Immunology · doi:10.1038/nri3738 · Cited by 1,882
Immunopathogenesis of IBD: current state of the art
de Souza, H. S. P., & Fiocchi, C. (2016) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2015.186 · Cited by 1,551
Chronic inflammation and cytokines in the tumor microenvironment
Landskron, G., De la Fuente, M., Thuwajit, P., Thuwajit, C., & Hermoso, M. A. (2014) · Journal of Immunology Research · doi:10.1155/2014/149185 · Cited by 1,765
Baseline gut microbiota predicts clinical response and colitis in metastatic melanoma patients treated with ipilimumab
Chaput, N., Lepage, P., Coutzac, C., Soularue, E., Le Roux, K., Monot, C., Boselli, L., Routier, E., Cassard, L., Collins, M., et al. (2017) · Annals of Oncology · doi:10.1093/annonc/mdx108 · Cited by 1,310
The gut microbiota in IBD
Manichanh, C., Borruel, N., Casellas, F., & Guarner, F. (2012) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2012.152 · Cited by 1,160
Anti-Inflammatory and Immunomodulatory Effects of Probiotics in Gut Inflammation: A Door to the Body
Cristofori, F., Dargenio, V. N., Dargenio, C., Miniello, V. L., Barone, M., & Francavilla, R. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.578386 · Cited by 985
Faecalibacterium prausnitzii : from microbiology to diagnostics and prognostics
López‐Siles, M., Duncan, S. H., Garcia-Gil, L. J., & Martínez-Medina, M. (2017) · The ISME Journal · doi:10.1038/ismej.2016.176 · Cited by 892
Gut microbiota imbalance and colorectal cancer
Gagnière, J. (2016) · World Journal of Gastroenterology · doi:10.3748/wjg.v22.i2.501 · Cited by 890
Roles for Intestinal Bacteria, Viruses, and Fungi in Pathogenesis of Inflammatory Bowel Diseases and Therapeutic Approaches
Sartor, R. B., & Wu, G. D. (2017) · Gastroenterology · doi:10.1053/j.gastro.2016.10.012 · Cited by 808
Human Intestinal Barrier Function in Health and Disease
König, J., Wells, J. M., Cani, P. D., García‐Ródenas, C. L., MacDonald, T. T., Mercenier, A., Whyte, J., Troost, F. J., & Brummer, R. J. (2016) · Clinical and Translational Gastroenterology · doi:10.1038/ctg.2016.54 · Cited by 811
Inflammatory bowel diseases (IBD) and the microbiome-searching the crime scene for clues
Lee, M., & Chang, E. B. (2021) · Gastroenterology · doi:10.1053/j.gastro.2020.09.056 · Cited by 645
Relationship between intestinal microbiota and ulcerative colitis: Mechanisms and clinical application of probiotics and fecal microbiota transplantation
Shen, Z.-H., Zhu, C.-X., Quan, Y.-S., Yang, Z.-Y., Wu, S., Luo, W.-W., Tan, B., & Wang, X.-Y. (2018) · World Journal of Gastroenterology · doi:10.3748/wjg.v24.i1.5 · Cited by 646
The Gut Microbiota in the Pathogenesis and Therapeutics of Inflammatory Bowel Disease
Zuo, T., & Ng, S. C. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.02247 · Cited by 605
Immunopathology of inflammatory bowel disease
Wallace, K. L. (2014) · World Journal of Gastroenterology · doi:10.3748/wjg.v20.i1.6 · Cited by 593
Fecal Lipocalin 2, a Sensitive and Broadly Dynamic Non-Invasive Biomarker for Intestinal Inflammation
Chassaing, B., Srinivasan, G., Delgado, M. A., Young, A. N., Gewirtz, A. T., & Vijay–Kumar, M. (2012) · PLoS ONE · doi:10.1371/journal.pone.0044328 · Cited by 584
Self-citation
Western diet induces dysbiosis with increased E coli in CEABAC10 mice , alters host barrier function favouring AIEC colonisation
Martinez-Medina, M., Denizot, J., Dreux, N., Robin, F., Billard, E., Bonnet, R., Darfeuille-Michaud, A., & Barnich, N. (2014) · Gut · doi:10.1136/gutjnl-2012-304119 · Cited by 539
Self-citation
High Prevalence of Mucosa-Associated E. coli Producing Cyclomodulin and Genotoxin in Colon Cancer
Buc, E., Dubois, D., Sauvanet, P., Raisch, J., Delmas, J., Darfeuille-Michaud, A., Pezet, D., & Bonnet, R. (2013) · PLoS ONE · doi:10.1371/journal.pone.0056964 · Cited by 535
Self-citation
Intestinal microbiota in health and disease: Role of bifidobacteria in gut homeostasis
Tojo, R. (2014) · World Journal of Gastroenterology · doi:10.3748/wjg.v20.i41.15163 · Cited by 533
Increased Proportions of Bifidobacterium and the Lactobacillus Group and Loss of Butyrate-Producing Bacteria in Inflammatory Bowel Disease
Wang, W., Chen, L., Zhou, R., Wang, X., Song, L., Huang, S., Wang, G., & Xia, B. (2014) · Journal of Clinical Microbiology · doi:10.1128/jcm.01500-13 · Cited by 509
Fecal microbiota transplantation as therapy for inflammatory bowel disease: A systematic review and meta-analysis
Colman, R. J., & Rubin, D. T. (2014) · Journal of Crohn's and Colitis · doi:10.1016/j.crohns.2014.08.006 · Cited by 475
Bacteriome and Mycobiome Interactions Underscore Microbial Dysbiosis in Familial Crohn’s Disease
Hoarau, G., Mukherjee, P. K., Gower‐Rousseau, C., Hager, C. L., Chandra, J., Retuerto, M. A., Neut, C., Vermeire, S., Clemente, J. C., Colombel, J., et al. (2016) · mBio · doi:10.1128/mbio.01250-16 · Cited by 499
A Map of Toll-like Receptor Expression in the Intestinal Epithelium Reveals Distinct Spatial, Cell Type-Specific, and Temporal Patterns
Price, A. E., Shamardani, K., Lugo, K. A., Deguine, J., Roberts, A. W., Lee, B. L., & Barton, G. M. (2018) · Immunity · doi:10.1016/j.immuni.2018.07.016 · Cited by 379
Interactions between Intestinal Microbiota and Host Immune Response in Inflammatory Bowel Disease
Zhang, M., Sun, K., Wu, Y., Yang, Y., Tso, P., & Wu, Z. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.00942 · Cited by 347
Structure and function: Lipid A modifications in commensals and pathogens
Steimle, A., Autenrieth, I. B., & Frick, J.-S. (2016) · International Journal of Medical Microbiology · doi:10.1016/j.ijmm.2016.03.001 · Cited by 373
Toll-like Receptors and Inflammatory Bowel Disease
Lu, Y., Li, X., Liu, S., Zhang, Y., & Zhang, D. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.00072 · Cited by 355
Intestinal epithelial cell toll-like receptor 5 regulates the intestinal microbiota to prevent low-grade inflammation and metabolic syndrome in mice
Chassaing, B., Ley, R. E., & Gewirtz, A. T. (2014) · Gastroenterology · doi:10.1053/j.gastro.2014.08.033 · Cited by 326
Microbiota-liver axis in hepatic disease
Chassaing, B., Etienne‐Mesmin, L., & Gewirtz, A. T. (2013) · Hepatology · doi:10.1002/hep.26494 · Cited by 333
Self-citation
Smoking and microbiome in oral, airway, gut and some systemic diseases
Huang, C., & Shi, G. (2019) · Journal of Translational Medicine · doi:10.1186/s12967-019-1971-7 · Cited by 288
The intestinal microbiota and chronic disorders of the gut
Dupont, A. W., & DuPont, H. L. (2011) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2011.133 · Cited by 310
Association between Faecalibacterium prausnitzii Reduction and Inflammatory Bowel Disease: A Meta-Analysis and Systematic Review of the Literature
Cao, Y., Shen, J., & Ran, Z. H. (2014) · Gastroenterology Research and Practice · doi:10.1155/2014/872725 · Cited by 307
Direct impact of commonly used dietary emulsifiers on human gut microbiota
Naimi, S., Viennois, É., Gewirtz, A. T., & Chassaing, B. (2021) · Microbiome · doi:10.1186/s40168-020-00996-6 · Cited by 329
Self-citation
Microbiota, Disease, and Back to Health: A Metastable Journey
Blumberg, R. S., & Powrie, F. M. (2012) · Science Translational Medicine · doi:10.1126/scitranslmed.3004184 · Cited by 287
Randomised clinical trial: the effectiveness of Lactobacillus reuteri ATCC 55730 rectal enema in children with active distal ulcerative colitis
Oliva, S., Nardo, G. D., Ferrari, F., Mallardo, S., Rossi, P., Patrizi, G., Cucchiara, S., & Stronati, L. (2011) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2011.04939.x · Cited by 280
IBD immunopathogenesis: A comprehensive review of inflammatory molecules
Park, J. H., Peyrin‐Biroulet, L., Eisenhut, M., & Shin, J. I. (2017) · Autoimmunity Reviews · doi:10.1016/j.autrev.2017.02.013 · Cited by 289
Dietary Emulsifier–Induced Low-Grade Inflammation Promotes Colon Carcinogenesis
Viennois, E., Merlin, D., Gewirtz, A. T., & Chassaing, B. (2017) · Cancer Research · doi:10.1158/0008-5472.can-16-1359 · Cited by 268
Self-citation
Nanoparticulate drug delivery systems targeting inflammation for treatment of inflammatory bowel disease
Zhang, S., Langer, R., & Traverso, G. (2017) · Nano Today · doi:10.1016/j.nantod.2017.08.006 · Cited by 256
Crohn's Disease–Associated Adherent Invasive Escherichia coli Modulate Levels of microRNAs in Intestinal Epithelial Cells to Reduce Autophagy
Nguyen, H. T. T., Dalmasso, G., Müller, S., Carrière, J., Seibold, F., & Darfeuille–Michaud, A. (2014) · Gastroenterology · doi:10.1053/j.gastro.2013.10.021 · Cited by 245
Self-citation
Prediction and quantification of bioactive microbiota metabolites in the mouse gut
Sridharan, G. V., Choi, K., Klemashevich, C. L., Wu, C., Prabakaran, D., Pan, L. B., Steinmeyer, S. H., Mueller, C., Yousofshahi, M., Alaniz, R. C., et al. (2014) · Nature Communications · doi:10.1038/ncomms6492 · Cited by 247
Crosstalk between Gut Microbiota and Host Immunity: Impact on Inflammation and Immunotherapy
Campbell, C., Kandalgaonkar, M. R., Golonka, R. M., Yeoh, B. S., Vijay–Kumar, M., & Saha, P. (2023) · Biomedicines · doi:10.3390/biomedicines11020294 · Cited by 265
Fecal Microbiota in Pediatric Inflammatory Bowel Disease and Its Relation to Inflammation
Kolho, K., Korpela, K., Jaakkola, T., Pichai, M. V. A., Zoetendal, E. G., Salonen, A., & de Vos, W. M. (2015) · The American Journal of Gastroenterology · doi:10.1038/ajg.2015.149 · Cited by 244
Faecalibacterium prausnitzii A2-165 has a high capacity to induce IL-10 in human and murine dendritic cells and modulates T cell responses
Rossi, O., van Berkel, L. A., Chain, F., Khan, M. T., Taverne, N., Sokol, H., Duncan, S. H., Flint, H. J., Harmsen, H. J. M., Langella, P., et al. (2016) · Scientific Reports · doi:10.1038/srep18507 · Cited by 250
Prebiotics, Probiotics, Synbiotics, Paraprobiotics and Postbiotic Compounds in IBD
Martyniak, A., Medyńska-Przęczek, A., Wędrychowicz, A., Skoczeń, S., & Tomasik, P. (2021) · Biomolecules · doi:10.3390/biom11121903 · Cited by 264
Faecal metabolite profiling identifies medium-chain fatty acids as discriminating compounds in IBD
Preter, V. D., Machiels, K., Joossens, M., Arijs, I., Matthys, C., Vermeire, S., Rutgeerts, P. J., & Verbeke, K. (2014) · Gut · doi:10.1136/gutjnl-2013-306423 · Cited by 238
Environmental risk factors for inflammatory bowel diseases: Evidence based literature review
Abegunde, A. T., Muhammad, B. H., Bhatti, O. I., & Ali, T. (2016) · World Journal of Gastroenterology · doi:10.3748/wjg.v22.i27.6296 · Cited by 250
Targeted deletion of MyD88 in intestinal epithelial cells results in compromised antibacterial immunity associated with downregulation of polymeric immunoglobulin receptor, mucin-2, and antibacterial peptides
Frantz, A. L., Rogier, E. W., Weber, C. R., Shen, L., Cohen, D. A., Fenton, L. A., Bruno, M. E. C., & Kaetzel, C. S. (2012) · Mucosal Immunology · doi:10.1038/mi.2012.23 · Cited by 230
The critical role of Faecalibacterium prausnitzii in human health: An overview
Leylabadlo, H. E., Ghotaslou, R., Feizabadi, M. M., Farajnia, S., Moaddab, S. Y., Ganbarov, K., Khodadadi, E., Tanomand, A., Sheykhsaran, E., Yousefi, B., et al. (2020) · Microbial Pathogenesis · doi:10.1016/j.micpath.2020.104344 · Cited by 245
The Microbiome and Inflammatory Bowel Disease: Is There a Therapeutic Role for Fecal Microbiota Transplantation?
Damman, C. J., Miller, S. I., Surawicz, C. M., & Zisman, T. L. (2012) · The American Journal of Gastroenterology · doi:10.1038/ajg.2012.93 · Cited by 229
Role of the enteric microbiota in intestinal homeostasis and inflammation
Koboziev, I., Webb, C. R., Furr, K. L., & Grisham, M. B. (2013) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2013.11.008 · Cited by 234
Characteristics of Fecal and Mucosa-Associated Microbiota in Chinese Patients With Inflammatory Bowel Disease
Chen, L., Wang, W., Zhou, R., Ng, S. C., Li, J., Huang, M., Zhou, F., Wang, X., Shen, B., Kamm, M. A., et al. (2014) · Medicine · doi:10.1097/md.0000000000000051 · Cited by 224
AIEC pathobiont instigates chronic colitis in susceptible hosts by altering microbiota composition
Chassaing, B., Koren, O., Carvalho, F. A., Ley, R. E., & Gewirtz, A. T. (2013) · Gut · doi:10.1136/gutjnl-2013-304909 · Cited by 239
Self-citation
The promise of the gut microbiome as part of individualized treatment strategies
Schupack, D. A., Mars, R. A. T., Voelker, D. H., Abeykoon, J. P., & Kashyap, P. C. (2022) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-021-00499-1 · Cited by 217
Fecal transplantation for treatment of inflammatory bowel disease
Imdad, A., Nicholson, M. R., Tanner‐Smith, E. E., Zackular, J. P., Gomez-Duarte, O. G., Beaulieu, D. B., & Acra, S. A. (2018) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012774.pub2 · Cited by 215
Probiotics: an update
Vandenplas, Y., Huys, G. R. B., & Daube, G. (2014) · Jornal de Pediatria · doi:10.1016/j.jped.2014.08.005 · Cited by 218
Gut Microbial Flora, Prebiotics, and Probiotics in IBD: Their Current Usage and Utility
Scaldaferri, F., Gerardi, V., Lopetuso, L. R., Zompo, F. D., Mangiola, F., Boškoski, I., Bruno, G., Petito, V., Laterza, L., Cammarota, G., et al. (2013) · BioMed Research International · doi:10.1155/2013/435268 · Cited by 207
Mucins in inflammatory bowel diseases and colorectal cancer
Sheng, Y., Hasnain, S. Z., Florin, T. H., & McGuckin, M. A. (2011) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2011.06909.x · Cited by 199
The Innate Immune Protein Nod2 Binds Directly to MDP, a Bacterial Cell Wall Fragment
Grimes, C. L., Ariyananda, L. D. Z., Melnyk, J. E., & O’Shea, E. K. (2012) · Journal of the American Chemical Society · doi:10.1021/ja303883c · Cited by 207
Microbiome, Metabolome and Inflammatory Bowel Disease
Ahmed, I., Roy, B. C., Khan, S., Septer, S. S., & Umar, S. (2016) · Microorganisms · doi:10.3390/microorganisms4020020 · Cited by 199
Persistent infection with Crohn’s disease-associated adherent-invasive Escherichia coli leads to chronic inflammation and intestinal fibrosis
Small, C.-L. N., Reid‐Yu, S. A., McPhee, J. B., & Coombes, B. K. (2013) · Nature Communications · doi:10.1038/ncomms2957 · Cited by 187
Vitamin D Modulates Intestinal Microbiota in Inflammatory Bowel Diseases
Battistini, C., Ballan, R., Herkenhoff, M. E., Saad, S. M. I., & Sun, J. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms22010362 · Cited by 196
The interplay between host immune cells and gut microbiota in chronic inflammatory diseases
Kim, D.-H., Zeng, M. Y., & Núñez, G. (2017) · Experimental & Molecular Medicine · doi:10.1038/emm.2017.24 · Cited by 191
The involvement of gut microbiota in inflammatory bowel disease pathogenesis: Potential for therapy
Cammarota, G., Ianiro, G., Cianci, R., Bibbò, S., Gasbarrini, A., & Currò, D. (2015) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2014.12.006 · Cited by 184
Intestinal microbiota, probiotics and prebiotics in inflammatory bowel disease
Orel, R. (2014) · World Journal of Gastroenterology · doi:10.3748/wjg.v20.i33.11505 · Cited by 177
Impacts of foodborne inorganic nanoparticles on the gut microbiota-immune axis: potential consequences for host health
Lamas, B., Breyner, N. M., & Houdeau, É. (2020) · Particle and Fibre Toxicology · doi:10.1186/s12989-020-00349-z · Cited by 182
The biodiversity and composition of the dominant fecal microbiota in patients with inflammatory bowel disease
Sha, S., Xu, B., Wang, X., Zhang, Y., Wang, H., Kong, X., Zhu, H., & Wu, K. (2012) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2012.11.022 · Cited by 165
Curcumin and Intestinal Inflammatory Diseases: Molecular Mechanisms of Protection
Burge, K. Y., Gunasekaran, A., Eckert, J. V., & Chaaban, H. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20081912 · Cited by 173
Enteric Glial Cells
Ochoa‐Cortés, F., Turco, F., Liñán-Rico, A., Soghomonyan, S., Whitaker, E. E., Wehner, S., Cuomo, R., & Christofi, F. L. (2015) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000667 · Cited by 169
Lactobacillus rhamnosus GG prevents epithelial barrier dysfunction induced by interferon-gamma and fecal supernatants from irritable bowel syndrome patients in human intestinal enteroids and colonoids
Han, X., Lee, A. A., Huang, S., Gao, J., Spence, J. R., & Owyang, C. (2018) · Gut Microbes · doi:10.1080/19490976.2018.1479625 · Cited by 162
When pathogenic bacteria meet the intestinal microbiota
Rolhion, N., & Chassaing, B. (2016) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2015.0504 · Cited by 170
Self-citation
Diet and microbiota in inflammatory bowel disease: The gut in disharmony
Rapozo, D. C. M., Bernardazzi, C., & de Souza, H. S. P. (2017) · World Journal of Gastroenterology · doi:10.3748/wjg.v23.i12.2124 · Cited by 169
Fecal transplantation for treatment of inflammatory bowel disease
Imdad, A., Nicholson, M. R., Tanner‐Smith, E. E., Zackular, J. P., Gomez-Duarte, O. G., Beaulieu, D. B., & Acra, S. A. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012774 · Cited by 158
Functional Impacts of the Intestinal Microbiome in the Pathogenesis of Inflammatory Bowel Disease
Li, J. S. Y., Butcher, J., Mack, D. R., & Stintzi, A. (2014) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000215 · Cited by 152
Cellular and Molecular Connections between Autophagy and Inflammation
Lapaquette, P., Guzzo, J., Brétillon, L., & Bringer, M.-A. (2015) · Mediators of Inflammation · doi:10.1155/2015/398483 · Cited by 155
The Gut Microbiota and Ageing
Maynard, C., & Weinkove, D. (2018) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-981-13-2835-0_12 · Cited by 152
Mucus Layers in Inflammatory Bowel Disease
Johansson, M. (2014) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000117 · Cited by 150
Crohn’s disease and the mycobacterioses: A quarter century later. Causation or simple association?
Chiodini, R. J., Chamberlin, W., Sarosiek, J., & McCallum, R. W. (2012) · Critical Reviews in Microbiology · doi:10.3109/1040841x.2011.638273 · Cited by 147
Innate immune dysfunction in inflammatory bowel disease
Gersemann, M., Wehkamp, J., & Stange, E. F. (2012) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2012.02515.x · Cited by 143
Crohn's Disease-Associated Adherent-Invasive Escherichia coli Adhesion Is Enhanced by Exposure to the Ubiquitous Dietary Polysaccharide Maltodextrin
Nickerson, K. P., & McDonald, C. (2012) · PLoS ONE · doi:10.1371/journal.pone.0052132 · Cited by 140
Impact of chronic exposure to low doses of chlorpyrifos on the intestinal microbiota in the Simulator of the Human Intestinal Microbial Ecosystem (SHIME) and in the rat
Joly, C., Gay-Quéheillard, J., Léké, A., Chardon, K., Delanaud, S., Bach, V., & Khorsi-Cauet, H. (2013) · Environmental Science and Pollution Research · doi:10.1007/s11356-012-1283-4 · Cited by 135
Mucosal Interactions between Genetics, Diet, and Microbiome in Inflammatory Bowel Disease
Basson, A. R., Trotter, A., Rodriguez‐Palacios, A., & Cominelli, F. (2016) · Frontiers in Immunology · doi:10.3389/fimmu.2016.00290 · Cited by 140
Influence of Microbiota on Intestinal Immune System in Ulcerative Colitis and Its Intervention
Zhang, S.-L., Wang, S., & Miao, C. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01674 · Cited by 139
Paneth cell defects in Crohn’s disease patients promote dysbiosis
Liu, T., Gurram, B., Baldridge, M. T., Head, R. D., Lam, V., Luo, C., Cao, Y., Simpson, P. M., Hayward, M., Holtz, M. L., et al. (2016) · JCI Insight · doi:10.1172/jci.insight.86907 · Cited by 134
The first international Rome consensus conference on gut microbiota and faecal microbiota transplantation in inflammatory bowel disease
Lopetuso, L. R., Deleu, S., Godny, L., Petito, V., Puca, P., Facciotti, F., Sokol, H., Ianiro, G., Masucci, L., Abreu, M., et al. (2023) · Gut · doi:10.1136/gutjnl-2023-329948 · Cited by 129
Dietary Emulsifiers Directly Impact Adherent-Invasive E. coli Gene Expression to Drive Chronic Intestinal Inflammation
Viennois, É., Bretin, A., Dubé, P. E., Maue, A. C., Dauriat, C. J. G., Barnich, N., Gewirtz, A. T., & Chassaing, B. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.108229 · Cited by 140
Self-citation
Differential Targeting of the E-Cadherin/β-Catenin Complex by Gram-Positive Probiotic Lactobacilli Improves Epithelial Barrier Function
Hummel, S., Veltman, K., Cichon, C., Sonnenborn, U., & Schmidt, M. A. (2011) · Applied and Environmental Microbiology · doi:10.1128/aem.06983-11 · Cited by 135
Comparing the effects of acute alcohol consumption in germ-free and conventional mice: the role of the gut microbiota
Canesso, M. C. C., Lacerda‐Queiroz, N., Cm, F., Gonçalves, J. L., de Almeida, D. L., Gamba, C. D. O., Cassali, G. D., Pedroso, S. H., Moreira, C. F., Martins, F. S., et al. (2014) · BMC Microbiology · doi:10.1186/s12866-014-0240-4 · Cited by 127
Colonic Microbiota Encroachment Correlates With Dysglycemia in Humans
Chassaing, B., Raja, S. M., Lewis, J. D., Srinivasan, S., & Gewirtz, A. T. (2017) · Cellular and Molecular Gastroenterology and Hepatology · doi:10.1016/j.jcmgh.2017.04.001 · Cited by 130
Self-citation
Flagellin-elicited adaptive immunity suppresses flagellated microbiota and vaccinates against chronic inflammatory diseases
Tran, H. Q., Ley, R. E., Gewirtz, A. T., & Chassaing, B. (2019) · Nature Communications · doi:10.1038/s41467-019-13538-y · Cited by 129
Self-citation
Genetic risk, dysbiosis, and treatment stratification using host genome and gut microbiome in inflammatory bowel disease
Moustafa, A. M., Li, W., Anderson, E. L., Wong, E., Dulai, P. S., Sandborn, W. J., Biggs, W., Yooseph, S., Jones, M. B., Venter, C. J., et al. (2018) · Clinical and Translational Gastroenterology · doi:10.1038/ctg.2017.58 · Cited by 116
Microbial imbalance and intestinal pathologies: connections and contributions
Yang, Y., & Jobin, C. (2014) · Disease Models & Mechanisms · doi:10.1242/dmm.016428 · Cited by 117
Research Gaps in Diet and Nutrition in Inflammatory Bowel Disease. A Topical Review by D-ECCO Working Group [Dietitians of ECCO]
Boneh, R. S., Levine, A., Lomer, M. C. E., Wierdsma, N., Allan, P., Fiorino, G., Gatti, S., Jonkers, D. M. A. E., Kierkuś, J., Katsanos, K. H., et al. (2017) · Journal of Crohn s and Colitis · doi:10.1093/ecco-jcc/jjx109 · Cited by 116
Autophagy and Crohn's Disease
Nguyen, H. T. T., Lapaquette, P., Bringer, M.-A., & Darfeuille–Michaud, A. (2013) · Journal of Innate Immunity · doi:10.1159/000345129 · Cited by 123
Self-citation
Characterization of adherent-invasive Escherichia coli isolated from pediatric patients with inflammatory bowel disease
Negroni, A., Costanzo, M., Vitali, R., Superti, F., Bertuccini, L., Tinari, A., Minelli, F., Nardo, G. D., Nuti, F., Pierdomenico, M., et al. (2011) · Inflammatory Bowel Diseases · doi:10.1002/ibd.21899 · Cited by 109
Deoxynivalenol as a New Factor in the Persistence of Intestinal Inflammatory Diseases: An Emerging Hypothesis through Possible Modulation of Th17-Mediated Response
Cano, P. M., Seeboth, J., Meurens, F., Cognié, J., Silva, R. A. M., Oswald, I. P., & Guzylack‐Piriou, L. (2013) · PLoS ONE · doi:10.1371/journal.pone.0053647 · Cited by 117
Checkpoint Inhibitor–Induced Colitis
Bellaguarda, E., & Hanauer, S. B. (2020) · The American Journal of Gastroenterology · doi:10.14309/ajg.0000000000000497 · Cited by 107
Gut Microbiota, Dietary Phytochemicals, and Benefits to Human Health
Yin, R., Kuo, H. D., Hudlikar, R. R., Sargsyan, D., Li, S. N., Wang, L., Wu, R., & Kong, A. T. (2019) · Current Pharmacology Reports · doi:10.1007/s40495-019-00196-3 · Cited by 108

Authors: Chassaing, B., & Darfeuille–Michaud, A.
Affiliations: Université Clermont Auvergne (FR)
Corresponding author: Darfeuille–Michaud, Arlette
Venue: Gastroenterology
Publisher: Elsevier BV
Published: 2011-05
Volume: 140
Issue: 6
Pages: 1720-1728.e3
ISSN: 0016-5085 (ISSN-L)
DOI: 10.1053/j.gastro.2011.01.054
OpenAlex: W2061275484
Cited by: 443
References: 129
Citations by year: 2026: 6 · 2025: 14 · 2024: 18 · 2023: 22 · 2022: 24 · 2021: 24 · 2020: 30 · 2019: 22 · 2018: 41 · 2017: 27 · 2016: 45 · 2015: 35 · 2014: 50 · 2013: 42 · 2012: 32
FWCI: 17.60
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Gastroenterology (publishedVersion)
PubMed (publishedVersion)
HAL (submittedVersion)
Funders: European Commission
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Health Sciences › Medicine › Gastroenterology › Inflammatory Bowel Disease
Health Sciences › Medicine › Gastroenterology › Microscopic Colitis
Keywords: inflammatory bowel disease, Crohn's disease, ulcerative colitis, commensal microbiota, dysbiosis, enteric pathogens, host-microbe interactions, intestinal barrier function, virulence factors, host susceptibility, gut microbiota
MeSH terms: Animals, Bacterial Infections, Colitis, Ulcerative, Crohn Disease, Humans, Intestines, Paratuberculosis, Mycobacterium avium subsp. paratuberculosis, Genetic Predisposition to Disease

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

The Commensal Microbiota and Enteropathogens in the Pathogenesis of Inflammatory Bowel Diseases

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks