Psychological disorder in asthma is associated with poor control and poor adherence to inhaled steroids
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Previous studies have linked psychological morbidity to poor control of asthma, but have not objectively measured adherence to treatment, and have linked poor adherence to depression, but have not measured asthma severity. This study assessed asthma and psychological morbidity and objectively measured adherence to medication and showed that psychological morbidity in those with asthma is significantly increased when control of asthma is poor, especially when control is poor and adherence to inhaled steroid regimen is low.
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Comorbid depression is often associated with a worse course of physical disorders, partly because depression is often associated with non-adherence to treatment regimens.
“comorbid depression is often associated with a worse course of the physical disorder.114–116 A number of reasons could be involved here, but one of the most consistently documented is that depression is often associated with non-adherence to treatment regimens.112, 117, 118”
From The Costs of Depression (2012) · cites this paper as [117]
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- Authors
- CLULEY, S., & COCHRANE, G. M.
- Affiliations
- Guy's Hospital (GB)
- Venue
- Respiratory Medicine
- Publisher
- Elsevier BV
- Published
- 2001-01
- Volume
- 95
- Issue
- 1
- Pages
- 37-39
- ISSN
- 0954-6111 (ISSN-L)
- OpenAlex
- W2025021729
- Cited by
- 160
- References
- 22
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 7 · 2023: 4 · 2022: 5 · 2021: 3 · 2020: 5 · 2019: 9 · 2018: 5 · 2017: 2 · 2016: 6 · 2015: 9 · 2014: 6 · 2013: 9 · 2012: 7
- FWCI
- 2.75
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Respiratory Medicine (publishedVersion)
- PubMed (publishedVersion)
- Funders
- British Lung Foundation
- Topics
- Health Sciences › Medicine › Physiology › Asthma and respiratory diseases
- Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Keywords
- asthma, psychological morbidity, depression, anxiety, asthma control, inhaled corticosteroids, medication adherence, asthma severity
- MeSH terms
- Administration, Topical, Adult, Analysis of Variance, Anti-Inflammatory Agents, Anxiety Disorders, Asthma, Mental Disorders, Depressive Disorder, Female, Glucocorticoids, Humans, Male, Middle Aged, Patient Compliance, Self Administration, Anti-Asthmatic Agents
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