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A Summary on Polycystic Ovary Syndrome: Diagnostic Criteria, Prevalence, Clinical Manifestations, and Management According to the Latest International Guidelines
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Polycystic ovary syndrome (PCOS) is a common hormonal condition with reproductive, metabolic, and psychological sequelae. The Rotterdam Criteria are now internationally accepted, with different phenotypes recognized with varying clinical presentations and risk profiles. The complexity of the disorder, and the impact on quality of life, requires timely diagnosis, screening for complications and management strategies. PCOS remains underdiagnosed and women experience significant delays to diagnosis. Effective dissemination of evidence-based management is therefore vital. In this review, we summarize key aspects of PCOS as a prelude to this issue of Seminars in Reproductive Medicine on PCOS which focuses on the development of the international evidence-based guideline on the assessment and management of PCOS and the related translation program. We cover diagnostic criteria, prevalence, phenotypes, reproductive, metabolic, and psychological factors of PCOS. We also cover management strategies including lifestyle interventions as well as treatment of nonreproductive outcomes and reproductive outcomes informed by the latest international evidence-based guidelines.
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“Obesity and abdominal obesity have a significant impact on psychosocial status, quality of life, hyperandrogenism, IR, lipid profiles, ovulation, menstrual cycle, fertility, risks for T2D, and cardiovascular disease onset [30, 31].”
From From Prediabetes to Type 2 Diabetes Mellitus in Women with Polycystic Ovary Syndrome: Lifestyle and Pharmacological Management (2020) · cites this paper as [31]
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Self-citation
Metadata
- Authors
- Neven, A., Laven, J., Teede, H., & Boyle, J.
- Affiliations
- Erasmus MC (NL)
- Monash University (AU)
- Monash Medical Centre (AU)
- Corresponding author
- Boyle, Jacqueline
- Venue
- Seminars in Reproductive Medicine
- Publisher
- Georg Thieme Verlag KG
- Published
- 2018-01
- Volume
- 36
- Issue
- 01
- Pages
- 005-012
- ISSN
- 1526-4564 (ISSN-L)
- 1526-8004
- OpenAlex
- W2891202838
- Cited by
- 196
- References
- 83
- Citations by year
- 2026: 9 · 2025: 22 · 2024: 29 · 2023: 32 · 2022: 43 · 2021: 35 · 2020: 18 · 2019: 8
- FWCI
- 2.30
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Seminars in Reproductive Medicine (publishedVersion)
- PubMed (publishedVersion)
- Monash University Research Portal (Monash University) (submittedVersion, other-oa)
- EUR Research Repository (Erasmus University Rotterdam) (submittedVersion)
- Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
- Funders
- National Health and Medical Research Council
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Health Sciences › Medicine › Reproductive Medicine › Reproductive Biology and Fertility
- Keywords
- polycystic ovary syndrome, Rotterdam criteria, PCOS phenotypes, prevalence, delayed diagnosis, reproductive outcomes, metabolic complications, psychological factors, lifestyle intervention, PCOS management, evidence-based recommendations, quality of life
- MeSH terms
- Female, Humans, Infertility, Female, Life Style, Polycystic Ovary Syndrome, Prevalence, Symptom Assessment
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