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Brine Shrimp: A Convenient General Bioassay for Active Plant Constituents
Abstract
A method, utilizing brine shrimp ( Artemia salina L EACH ), is proposed as a simple bioassay for natural product research. The procedure determines LC 50 values in µg/ml of active compounds and extracts in the brine medium. Activities of a broad range of known active compounds are manifested as toxicity to the shrimp. Screening results with seed extracts of 41 species of Euphorbiaceae were compared with 9KB and 9PS cytotoxicities. The method is rapid, reliable, inexpensive, and convenient as an in-house general bioassay tool. Key Word Index Artemia salina - Brine shrimp - Bioassay methods - Euphorbiaceae seeds - 9KB and 9PS cytotoxicities
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Bioactivities from marine algae of the genus Gracilaria
De Almeida, C. L. F., De S. Falcão, H., De M. Lima, G. R., De A. Montenegro, C., Lira, N. S., De Athayde-Filho, P. F., Rodrigues, L. C., De Souza, M. D. F. V., Barbosa-Filho, J. M., & Batista, L. M. (2011) · International Journal of Molecular Sciences · doi:10.3390/ijms12074550 · Cited by 252
Kapadia, G. J., Azuine, M. A., Tokuda, H., Takasaki, M., Mukainaka, T., Konoshima, T., & Nishino, H. (2002) · Pharmacological Research · doi:10.1006/phrs.2002.0992 · Cited by 238
Almeida, E. J. R., & Corso, C. R. (2014) · Chemosphere · doi:10.1016/j.chemosphere.2014.04.060 · Cited by 191
Nejrotti, S., Antenucci, A., Pontremoli, C., Gontrani, L., Barbero, N., Carbone, M., & Bonomo, M. (2022) · ACS Omega · doi:10.1021/acsomega.2c06140 · Cited by 111
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Cansian, R. L., Vanin, A. B., Orlando, T., Piazza, S. P., Puton, B. M. S., Cardoso, R. I., Gonçalves, I. L., Honaiser, T. C., Paroul, N., & Oliveira, D. (2017) · Brazilian Journal of Biology · doi:10.1590/1519-6984.12215 · Cited by 67
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Singh, D., Sharma, D., & Agarwal, V. (2021) · Journal of Ayurveda and Integrative Medicine · doi:10.1016/j.jaim.2021.06.007 · Cited by 35
The Use of HRP in Decolorization of Reactive Dyes and Toxicological Evaluation of Their Products
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Use of the Lactococcus lactis IO-1 for developing a novel functional beverage from coconut water
Faculty of Resource Science & Technology, U. M. S., Olaide, A. O., Lihan, S., Institute of Biodiversity and Environmental Conservation, U. M. S., Husain, A. A. S. A., Faculty of Resource Science & Technology, U. M. S., Saat, R., Faculty of Resource Science & Technology, U. M. S., Mohammad, F. S., Faculty of Resource Science & Technology, U. M. S., et al. (2020) · The Annals of the University Dunarea de Jos of Galati Fascicle VI – Food Technology · doi:10.35219/foodtechnology.2020.1.07 · Cited by 10
Metadata
- Authors
- Meyer, B., Ferrigni, N., Putnam, J., Jacobsen, L., Nichols, D., & McLaughlin, J.
- Venue
- Planta Medica
- Publisher
- Georg Thieme Verlag KG
- Published
- 1982-05
- Volume
- 45
- Issue
- 05
- Pages
- 31-34
- ISSN
- 0032-0943 (ISSN-L)
- 1439-0221
- OpenAlex
- W2074509460
- Cited by
- 4,831
- References
- 0
- FWCI
- 1.15
- Type
- journal article
- Language
- en
- Open access
- closed
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