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Cited by 382

The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.

Value of Electron-Beam Computed Tomography for the Noninvasive Detection of High-Grade Coronary-Artery Stenoses and Occlusions

Open access
Achenbach, Stephan, Moshage, Werner, Ropers, Dieter, Nossen, Jörg, Daniel, Werner G.·1998·New England Journal of Medicine

Abstract

BACKGROUND: Reliable noninvasive assessment of coronary-artery stenoses and occlusions would constitute an advantage in the care of patients with known or suspected coronary artery disease. We investigated the accuracy of contrast-enhanced electron-beam computed tomography (CT) for the detection of high-grade coronary-artery stenoses and occlusions. METHODS: Electron-beam CT was performed in 125 patients. After intravenous injection of a contrast agent, 40 cross-sectional images of the heart were acquired during inspiration, triggered by the electrocardiogram in diastole. Three-dimensional reconstructions of the heart and coronary arteries were rendered to facilitate evaluation of the images. The proximal and middle segments of the major coronary arteries were evaluated for the presence or absence of high-grade stenoses and occlusions. The results were compared with those of invasive coronary angiography in a blinded fashion. RESULTS: Because of technical problems that impaired the quality of the images, 124 (25 percent) of the 500 coronary arteries studied (left main, left anterior descending, left circumflex, and right coronary) in a total of 125 patients were excluded from evaluation. No vessels could be evaluated in 19 patients (15 percent), and another 28 patients (22 percent) had one, two, or three vessels that could not be evaluated. In the remaining coronary arteries with adequate image quality, electron-beam CT permitted visualization of 69 of 75 high-grade stenoses and occlusions (sensitivity, 92 percent), whereas in 282 of 301 arteries, the absence of high-grade stenoses and occlusions was correctly detected (specificity, 94 percent). CONCLUSIONS: When image quality is adequate, electron-beam CT may be useful to detect or rule out high-grade coronary-artery stenoses and occlusions.

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Metadata

Authors
Achenbach, S., Moshage, W., Ropers, D., Nossen, J., & Daniel, W. G.
Venue
New England Journal of Medicine
Published
1998-12-31
Volume
339
Issue
27
Pages
1964-1971
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
OpenAlex
W2334010292
Cited by
382
References
22
FWCI
34.54
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Value of Electron-Beam Computed Tomography for the Noninvasive Detection of High-Grade Coronary-Artery Stenoses and Occlusions. https://app.cochat.ai/papers/10.1056/nejm199812313392702
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Achenbach, S., Moshage, W., Ropers, D., Nossen, J., & Daniel, W. G. (1998). Value of Electron-Beam Computed Tomography for the Noninvasive Detection of High-Grade Coronary-Artery Stenoses and Occlusions. New England Journal of Medicine. https://doi.org/10.1056/nejm199812313392702

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