Cited by 3,643Obesity, Physical Activity, DietCancer Risks and FactorsDiabetes, Cardiovascular Risks, and Lipoproteins

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Body-Mass Index and Mortality in a Prospective Cohort of U.S. Adults

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Calle, Eugenia E., Thun, Michael J., Petrelli, Jennifer M., Rodriguez, Carmen, Heath, Clark W.·1999·New England Journal of Medicine

DOI 10.1056/nejm199910073411501

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Abstract

BACKGROUND: Body-mass index (the weight in kilograms divided by the square of the height in meters) is known to be associated with overall mortality. We investigated the effects of age, race, sex, smoking status, and history of disease on the relation between body-mass index and mortality. METHODS: In a prospective study of more than 1 million adults in the United States (457,785 men and 588,369 women), 201,622 deaths occurred during 14 years of follow-up. We examined the relation between body-mass index and the risk of death from all causes in four subgroups categorized according to smoking status and history of disease. In healthy people who had never smoked, we further examined whether the relation varied according to race, cause of death, or age. The relative risk was used to assess the relation between mortality and body-mass index. RESULTS: The association between body-mass index and the risk of death was substantially modified by smoking status and the presence of disease. In healthy people who had never smoked, the nadir of the curve for body-mass index and mortality was found at a body-mass index of 23.5 to 24.9 in men and 22.0 to 23.4 in women. Among subjects with the highest body-mass indexes, white men and women had a relative risk of death of 2.58 and 2.00, respectively, as compared with those with a body-mass index of 23.5 to 24.9. Black men and women with the highest body-mass indexes had much lower risks of death (1.35 and 1.21), which did not differ significantly from 1.00. A high body-mass index was most predictive of death from cardiovascular disease, especially in men (relative risk, 2.90; 95 percent confidence interval, 2.37 to 3.56). Heavier men and women in all age groups had an increased risk of death. CONCLUSIONS: The risk of death from all causes, cardiovascular disease, cancer, or other diseases increases throughout the range of moderate and severe overweight for both men and women in all age groups. The risk associated with a high body-mass index is greater for whites than for blacks.

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Regression Models and Life-Tables
Cox, D. R. (1972) · Journal of the Royal Statistical Society Series B: Statistical Methodology · doi:10.1111/j.2517-6161.1972.tb00899.x · Cited by 39,793
Regression Models and Life-Tables
Cox, D. R. (1992) · Springer Series in Statistics · doi:10.1007/978-1-4612-4380-9_37 · Cited by 26,297
Indices of relative weight and obesity
Keys, A. B., Fidanza, F., Karvonen, M. J., Kimura, N., & TAYLOR, H. L. (1972) · Journal of Chronic Diseases · doi:10.1016/0021-9681(72)90027-6 · Cited by 2,085
Body Weight and Mortality among Women
Manson, J. E., Willett, W. C., Stampfer, M. J., Colditz, G. A., Hunter, D. J., Hankinson, S. E., Hennekens, C. H., & Speizer, F. E. (1995) · New England Journal of Medicine · doi:10.1056/nejm199509143331101 · Cited by 2,005
The effect of age on the association between body-mass index and mortality
Stevens, J., Cai, J., Pamuk, E. R., Williamson, D. F., Thun, M. J., & Wood, J. L. (1998) · New England Journal of Medicine · doi:10.1056/nejm199801013380101 · Cited by 1,611
Self-citation
Variations in mortality by weight among 750,000 men and women
Lew, E. A., & Garfinkel, L. (1979) · Journal of Chronic Diseases · doi:10.1016/0021-9681(79)90119-x · Cited by 1,169
Manual of the International Statistical Classification of Diseases, Injuries, and Causes of Death.
Schneider, B. A. (1953) · The Quarterly Review of Biology · doi:10.1086/399926 · Cited by 1,000
A Prospective Study of Body Mass Index, Weight Change, and Risk of Stroke in Women
Rexrode, K. M. (1997) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1997.03540430051032 · Cited by 617
Body Fat Distribution and 5-Year Risk of Death in Older Women
Folsom, A. R. (1993) · JAMA · doi:10.1001/jama.1993.03500040049035 · Cited by 611
Body weight and longevity. A reassessment
Manson, J. E. (1987) · JAMA · doi:10.1001/jama.257.3.353 · Cited by 597

Show all 41 references

Research works printed but not linked: 6

Lindsted K, 1991, Int J Obes, 15, 397
Troiano RP, 1996, Int J Obes Relat Metab Disord, 20, 63
Department of Agriculture, Department of Health and Human Services. Nutrition and your health: dietary guidelines for Americans. 4th ed. Home and garden bulletin no. 232. Washington, D.C.: Government Printing Office, 1995.
10.1001/archinte.152.6.1257 · DOI
1995, WHO Tech Rep Ser, 854, 1
Dunn SE, 1997, Cancer Res, 57, 4667

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Berry, R., Jeffery, E. C., & Rodeheffer, M. S. (2013) · Cell Metabolism · doi:10.1016/j.cmet.2013.10.003 · Cited by 246
Weight gain and its predictors in Chinese adults
Bell, A., Ge, K., & Popkin, B. (2001) · International Journal of Obesity · doi:10.1038/sj.ijo.0801651 · Cited by 244
Rationale for Redefining Obesity in Asians
Low, S. K., Chin, M. C., Ma, S., Heng, D., & Deurenberg‐Yap, M. (2009) · Annals of the Academy of Medicine Singapore · doi:10.47102/annals-acadmedsg.v38n1p66 · Cited by 244
Serum Levels of Interleukin‐6 and C‐Reactive Protein Correlate With Body Mass Index Across the Broad Range of Obesity
Khaodhiar, L., Ling, P., Blackburn, G. L., & Bistrian, B. R. (2004) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/0148607104028006410 · Cited by 243
Effects of Candesartan Compared With Amlodipine in Hypertensive Patients With High Cardiovascular Risks
Ogihara, T., Nakao, K., Fukui, T., Fukiyama, K., Ueshima, K., Oba, K., Sato, T. S., & Saruta, T. (2008) · Hypertension · doi:10.1161/hypertensionaha.107.098475 · Cited by 243
Obesity: Overview of Prevalence, Etiology, and Treatment
Racette, S. B., Deusinger, S. S., & Deusinger, R. H. (2003) · Physical Therapy · doi:10.1093/ptj/83.3.276 · Cited by 243
Body Mass Index Is Inversely Related to Mortality in Older People After Adjustment for Waist Circumference
Janssen, I., Katzmarzyk, P. T., & Ross, R. (2005) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2005.00505.x · Cited by 242
Paradoxical Association Between Body Mass Index and Mortality in Men With CKD Not Yet on Dialysis
Kovesdy, C. P., Anderson, J. E., & Kalantar‐Zadeh, K. (2007) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2007.02.277 · Cited by 242
2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS Guideline for the Diagnosis and Management of Patients With Stable Ischemic Heart Disease: Executive Summary
Fihn, S. D., Gardin, J. M., Abrams, J., Berra, K., Blankenship, J. C., Dallas, A. P., Douglas, P. S., Foody, J. M., Gerber, T. C., Hinderliter, A. L., et al. (2012) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2012.07.012 · Cited by 242
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Berger, N. A. (2014) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.12416 · Cited by 241
Muscle mass, BMI, and mortality among adults in the United States: A population-based cohort study
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Dunlop, D. D., Semanik, P. A., Song, J., Manheim, L. M., Shih, V., & Chang, R. W. (2005) · Arthritis & Rheumatism · doi:10.1002/art.20968 · Cited by 235
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Lü, J., Molnar, M. Z., Naseer, A., Mikkelsen, M. K., Kalantar‐Zadeh, K., & Kovesdy, C. P. (2015) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(15)00128-x · Cited by 233
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Reynolds, M. A. (2013) · Periodontology 2000 · doi:10.1111/prd.12047 · Cited by 233
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Zalesin, K. C., Franklin, B. A., Miller, W. M., Peterson, E. D., & McCullough, P. A. (2011) · Medical Clinics of North America · doi:10.1016/j.mcna.2011.06.005 · Cited by 231
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Bales, C. W., & Buhr, G. T. (2008) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2008.01.006 · Cited by 231
Clinical aspects of obesity in childhood and adolescence
Kiess, W., Galler, A., Reich, A., Müller, G., Kapellen, T. M., Deutscher, J., Raile, K., & Kratzsch, J. (2001) · Obesity Reviews · doi:10.1046/j.1467-789x.2001.00017.x · Cited by 231
Gender Disparities in Adult Health: An Examination of Three Measures of Morbidity
Gorman, B. K., & Read, J. G. (2006) · Journal of Health and Social Behavior · doi:10.1177/002214650604700201 · Cited by 231
Body Mass Index and Mortality Among Hospitalized Patients
Landi, F. (2000) · Archives of Internal Medicine · doi:10.1001/archinte.160.17.2641 · Cited by 230
A MUFA-Rich Diet Improves Posprandial Glucose, Lipid and GLP-1 Responses in Insulin-Resistant Subjects
Paniagua, J. A., de la Sacristana, A. G., García, M. E. S., Romero, I., Vidal‐Puig, A., de la Rosa, F. J. B., Escribano, A., Moyano, M. J., Pérez‐Martínez, P., López‐Miranda, J., et al. (2007) · Journal of the American College of Nutrition · doi:10.1080/07315724.2007.10719633 · Cited by 230
Extreme Obesity: A New Medical Crisis in the United States
Hensrud, D. D., & Klein, S. (2006) · Mayo Clinic Proceedings · doi:10.1016/s0025-6196(11)61175-0 · Cited by 229
Hyperinsulinemia and Autonomic Nervous System Dysfunction in Obesity
Emdin, M., Gastaldelli, A., Muscelli, E., Macerata, A., Natali, A., Camastra, S., & Ferrannini, E. (2001) · Circulation · doi:10.1161/01.cir.103.4.513 · Cited by 229
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Authors: Calle, E. E., Thun, M. J., Petrelli, J. M., Rodriguez, C., & Heath, C. W.
Affiliations: American Cancer Society (US)
ORCID: Calle, Eugenia E.
Venue: New England Journal of Medicine
Publisher: Massachusetts Medical Society
Published: 1999-10-07
Volume: 341
Issue: 15
Pages: 1097-1105
ISSN: 0028-4793 (ISSN-L)
1533-4406
DOI: 10.1056/nejm199910073411501
OpenAlex: W2323202746
Cited by: 3,643
References: 41
Citations by year: 2026: 14 · 2025: 29 · 2024: 48 · 2023: 66 · 2022: 73 · 2021: 76 · 2020: 114 · 2019: 79 · 2018: 81 · 2017: 118 · 2016: 128 · 2015: 138 · 2014: 178 · 2013: 178 · 2012: 165
FWCI: 132.54
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: New England Journal of Medicine (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
Health Sciences › Medicine › Oncology › Cancer Risks and Factors
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Keywords: body mass index, obesity, mortality, cardiovascular mortality, cancer mortality, smoking status, racial differences, sex differences, age differences, overweight, disease history
MeSH terms: Adult, Age Factors, Black or African American, Cardiovascular Diseases, Cause of Death, Female, Humans, Male, Mortality, Neoplasms, Obesity, Prospective Studies, Risk, Smoking, United States, Body Mass Index, Multivariate Analysis, Black People, White People

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Body-Mass Index and Mortality in a Prospective Cohort of U.S. Adults

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