Cited by 3,643Obesity, Physical Activity, DietCancer Risks and FactorsDiabetes, Cardiovascular Risks, and Lipoproteins

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Body-Mass Index and Mortality in a Prospective Cohort of U.S. Adults

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Calle, Eugenia E., Thun, Michael J., Petrelli, Jennifer M., Rodriguez, Carmen, Heath, Clark W.·1999·New England Journal of Medicine

DOI 10.1056/nejm199910073411501

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Abstract

BACKGROUND: Body-mass index (the weight in kilograms divided by the square of the height in meters) is known to be associated with overall mortality. We investigated the effects of age, race, sex, smoking status, and history of disease on the relation between body-mass index and mortality. METHODS: In a prospective study of more than 1 million adults in the United States (457,785 men and 588,369 women), 201,622 deaths occurred during 14 years of follow-up. We examined the relation between body-mass index and the risk of death from all causes in four subgroups categorized according to smoking status and history of disease. In healthy people who had never smoked, we further examined whether the relation varied according to race, cause of death, or age. The relative risk was used to assess the relation between mortality and body-mass index. RESULTS: The association between body-mass index and the risk of death was substantially modified by smoking status and the presence of disease. In healthy people who had never smoked, the nadir of the curve for body-mass index and mortality was found at a body-mass index of 23.5 to 24.9 in men and 22.0 to 23.4 in women. Among subjects with the highest body-mass indexes, white men and women had a relative risk of death of 2.58 and 2.00, respectively, as compared with those with a body-mass index of 23.5 to 24.9. Black men and women with the highest body-mass indexes had much lower risks of death (1.35 and 1.21), which did not differ significantly from 1.00. A high body-mass index was most predictive of death from cardiovascular disease, especially in men (relative risk, 2.90; 95 percent confidence interval, 2.37 to 3.56). Heavier men and women in all age groups had an increased risk of death. CONCLUSIONS: The risk of death from all causes, cardiovascular disease, cancer, or other diseases increases throughout the range of moderate and severe overweight for both men and women in all age groups. The risk associated with a high body-mass index is greater for whites than for blacks.

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Regression Models and Life-Tables
Cox, D. R. (1972) · Journal of the Royal Statistical Society Series B: Statistical Methodology · doi:10.1111/j.2517-6161.1972.tb00899.x · Cited by 39,793
Regression Models and Life-Tables
Cox, D. R. (1992) · Springer Series in Statistics · doi:10.1007/978-1-4612-4380-9_37 · Cited by 26,297
Indices of relative weight and obesity
Keys, A. B., Fidanza, F., Karvonen, M. J., Kimura, N., & TAYLOR, H. L. (1972) · Journal of Chronic Diseases · doi:10.1016/0021-9681(72)90027-6 · Cited by 2,085
Body Weight and Mortality among Women
Manson, J. E., Willett, W. C., Stampfer, M. J., Colditz, G. A., Hunter, D. J., Hankinson, S. E., Hennekens, C. H., & Speizer, F. E. (1995) · New England Journal of Medicine · doi:10.1056/nejm199509143331101 · Cited by 2,005
The effect of age on the association between body-mass index and mortality
Stevens, J., Cai, J., Pamuk, E. R., Williamson, D. F., Thun, M. J., & Wood, J. L. (1998) · New England Journal of Medicine · doi:10.1056/nejm199801013380101 · Cited by 1,611
Self-citation
Variations in mortality by weight among 750,000 men and women
Lew, E. A., & Garfinkel, L. (1979) · Journal of Chronic Diseases · doi:10.1016/0021-9681(79)90119-x · Cited by 1,169
Manual of the International Statistical Classification of Diseases, Injuries, and Causes of Death.
Schneider, B. A. (1953) · The Quarterly Review of Biology · doi:10.1086/399926 · Cited by 1,000
A Prospective Study of Body Mass Index, Weight Change, and Risk of Stroke in Women
Rexrode, K. M. (1997) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1997.03540430051032 · Cited by 617
Body Fat Distribution and 5-Year Risk of Death in Older Women
Folsom, A. R. (1993) · JAMA · doi:10.1001/jama.1993.03500040049035 · Cited by 611
Body weight and longevity. A reassessment
Manson, J. E. (1987) · JAMA · doi:10.1001/jama.257.3.353 · Cited by 597

Show all 41 references

Research works printed but not linked: 6

Lindsted K, 1991, Int J Obes, 15, 397
Troiano RP, 1996, Int J Obes Relat Metab Disord, 20, 63
Department of Agriculture, Department of Health and Human Services. Nutrition and your health: dietary guidelines for Americans. 4th ed. Home and garden bulletin no. 232. Washington, D.C.: Government Printing Office, 1995.
10.1001/archinte.152.6.1257 · DOI
1995, WHO Tech Rep Ser, 854, 1
Dunn SE, 1997, Cancer Res, 57, 4667

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Evaluating and treating unintentional weight loss in the elderly.
Huffman, G. B. (2002) · PubMed · Cited by 153
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Ray, E., Nickels, M. W., Sayeed, S., & Sax, H. C. (2003) · Surgery · doi:10.1016/s0039-6060(03)00279-4 · Cited by 153
European guidelines on cardiovascular disease prevention in clinical practice: third joint task force of European and other societies on cardiovascular disease prevention in clinical practice (constituted by representatives of eight societies and by invited experts).
Backer, G. D., Ambrosio, G., Borch‐Johnsen, K., Brotons, C., Cífková, R., Dallongeville, J., Ebrahim, S. B. J., Færgeman, O., Graham, I. D., Mancia, G., et al. (2003) · PubMed · doi:10.1097/01.hjr.0000087913.96265.e2 · Cited by 153
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(2011) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2011.09.008 · Cited by 152
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Lev-Ran, A. (2001) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.230 · Cited by 152
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Ioannides‐Demos, L. L., Proietto, J., Tonkin, A. M., & McNeil, J. J. (2006) · Drug Safety · doi:10.2165/00002018-200629040-00001 · Cited by 152
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Luder, E., Ehrlich, R. I., Lou, W. Y. W., Melnik, T. A., & Kattan, M. (2003) · Respiratory Medicine · doi:10.1016/j.rmed.2003.08.004 · Cited by 152
Obesity and psychopathology in women: a three decade prospective study
Kasen, S., Cohen, P. R., Chen, H., & Must, A. (2007) · International Journal of Obesity · doi:10.1038/sj.ijo.0803736 · Cited by 152
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Freedman, D. M., Sigurdson, A. J., Rajaraman, P., Doody, M. M., Linet, M. S., & Ron, E. (2006) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2006.07.022 · Cited by 152
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Bucholz, E. M., Rathore, S. S., Reid, K. J., Jones, P. G., Chan, P. S., Rich, M. W., Spertus, J. A., & Krumholz, H. M. (2012) · The American Journal of Medicine · doi:10.1016/j.amjmed.2012.01.018 · Cited by 151
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Ryan, A. M., Duong, M. T., Healy, L., Ryan, S. A., Parekh, N., Reynolds, J. V., & Power, D. G. (2011) · Cancer Epidemiology · doi:10.1016/j.canep.2011.03.001 · Cited by 151
Original Article Underweight, overweight and obesity
Katzmarzyk, P. T., Craig, C. L., & Bouchard, C. (2001) · Journal of Clinical Epidemiology · doi:10.1016/s0895-4356(01)00356-0 · Cited by 151
Surgical treatment of obesity
Kral, J. G., & Näslund, E. B. (2007) · Nature Clinical Practice Endocrinology & Metabolism · doi:10.1038/ncpendmet0563 · Cited by 151
Regulation of Lipogenesis by Glucocorticoids and Insulin in Human Adipose Tissue
Gathercole, L. L., Morgan, S. A., Bujalska, I. J., Hauton, D., Stewart, P. M., & Tomlinson, J. W. (2011) · PLoS ONE · doi:10.1371/journal.pone.0026223 · Cited by 150
Effects of body size and hypertension treatments on cardiovascular event rates: subanalysis of the ACCOMPLISH randomised controlled trial
Weber, M. A., Jamerson, K., Bakris, G. L., Weir, M. R., Zappe, D., Zhang, Y., Dahlof, B., Velazquez, E. J., & Pitt, B. (2013) · The Lancet · doi:10.1016/s0140-6736(12)61343-9 · Cited by 150
Obesity and Kidney Transplant Candidates: How Big Is Too Big for Transplantation?
Lentine, K. L., Santos, R. D., Axelrod, D. A., Schnitzler, M. A., Brennan, D. C., & Tuttle-Newhall, J. E. (2012) · American Journal of Nephrology · doi:10.1159/000345476 · Cited by 150
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Evaluation of nutritional status in advanced metastatic cancer
Sarhill, N., Mahmoud, F. A., Walsh, D., Nelson, K. A., Kömürcü, Ş., Davis, M. P., LeGrand, S. B., Abdullah, O., & Rybicki, L. A. (2003) · Supportive Care in Cancer · doi:10.1007/s00520-003-0486-0 · Cited by 150
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Monteforte, M. J., & Turkelson, C. M. (2000) · Obesity Surgery · doi:10.1381/096089200321594246 · Cited by 149
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Body mass index and mortality among US male physicians
Ajani, U. A., Lotufo, P. A., Gaziano, J. M., Lee, I.-M. M., Spelsberg, A., Buring, J. E., Willett, W. C., & Manson, J. E. (2004) · Annals of Epidemiology · doi:10.1016/j.annepidem.2003.10.008 · Cited by 147
Obesity and the Risk for Cardiovascular Disease
Rashid, M. N., Fuentes, F., Touchon, R. C., & Wehner, P. S. (2003) · Preventive Cardiology · doi:10.1111/j.1520-037x.2003.01358.x · Cited by 146
Obesity, Abdominal Obesity, and Insulin Resistance
Westphal, S. A. (2008) · Clinical cornerstone · doi:10.1016/s1098-3597(08)60025-3 · Cited by 146
Current status of intragastric balloon for obesity treatment
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Authors: Calle, E. E., Thun, M. J., Petrelli, J. M., Rodriguez, C., & Heath, C. W.
Affiliations: American Cancer Society (US)
ORCID: Calle, Eugenia E.
Venue: New England Journal of Medicine
Publisher: Massachusetts Medical Society
Published: 1999-10-07
Volume: 341
Issue: 15
Pages: 1097-1105
ISSN: 0028-4793 (ISSN-L)
1533-4406
DOI: 10.1056/nejm199910073411501
OpenAlex: W2323202746
Cited by: 3,643
References: 41
Citations by year: 2026: 14 · 2025: 29 · 2024: 48 · 2023: 66 · 2022: 73 · 2021: 76 · 2020: 114 · 2019: 79 · 2018: 81 · 2017: 118 · 2016: 128 · 2015: 138 · 2014: 178 · 2013: 178 · 2012: 165
FWCI: 132.54
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: New England Journal of Medicine (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
Health Sciences › Medicine › Oncology › Cancer Risks and Factors
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Keywords: body mass index, obesity, mortality, cardiovascular mortality, cancer mortality, smoking status, racial differences, sex differences, age differences, overweight, disease history
MeSH terms: Adult, Age Factors, Black or African American, Cardiovascular Diseases, Cause of Death, Female, Humans, Male, Mortality, Neoplasms, Obesity, Prospective Studies, Risk, Smoking, United States, Body Mass Index, Multivariate Analysis, Black People, White People

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Body-Mass Index and Mortality in a Prospective Cohort of U.S. Adults

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