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Hepatotoxicity with Combination of Vemurafenib and Ipilimumab
Abstract
The independent mechanisms of action and largely nonoverlapping toxicity profiles of vemurafenib and ipilimumab made it logical to test them together in a study of patients with melanoma. An unexpected level of hepatic toxicity caused the early termination of the study.
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Metadata
- Authors
- Ribas, A., Hodi, F. S., Callahan, M., Konto, C., & Wolchok, J.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2013-04-04
- Volume
- 368
- Issue
- 14
- Pages
- 1365-1366
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2040956995
- Cited by
- 714
- References
- 1
- FWCI
- 56.44
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
