The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Neuropathological Features of Covid-19
Open accessAbstract
Brain Autopsy Series in Patients with Covid-19 Eighteen brains of patients who died 0 to 32 days after the onset of symptoms of SARS-CoV-2 infection showed hypoxic–ischemic changes but no encephali...
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“a study carried out on the brains of 18 adults between the ages of 53 and 75 fallen victim to the virus revealed neither CT-informed macrostructural abnormalities, nor microstructural damage ascribable to the virus, but only mild hypoxia-related modifications with, importantly, limited evidence of viral presence in the brain (34).”
From The impact of COVID-19 infection and enforced prolonged social isolation on neuropsychiatric symptoms in older adults with and without dementia: A review (2020) · cites this paper as [34]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China
Mao, L., Jin, H., Wang, M., Hu, Y., Chen, S., He, Q., Chang, J., Hong, C., Zhou, Y., Wang, D., et al. (2020) · JAMA Neurology · doi:10.1001/jamaneurol.2020.1127 · Cited by 7,166
Lechien, J. R., Chiesa-Estomba, C. M., De Siati, D. R., Horoi, M., Le Bon, S. D., Rodriguez, A., Dequanter, D., Blecic, S., El Afia, F., Distinguin, L., et al. (2020) · European Archives of Oto-Rhino-Laryngology · doi:10.1007/s00405-020-05965-1 · Cited by 2,668
Giacomelli, A., Pezzati, L., Conti, F., Bernacchia, D., Siano, M., Oreni, L., Rusconi, S., Gervasoni, C., Ridolfo, A. L., Rizzardini, G., et al. (2020) · Clinical Infectious Diseases · doi:10.1093/cid/ciaa330 · Cited by 1,326
Flagged first, then by citations
Cited by
Sorted by citations
Items 601–700 of 822
Ultrasound COVID-19 Classification Based on the Novel Module-Based Dual-Path Network
Fang, L., & Wang, X. (2022) · IEEE Transactions on Artificial Intelligence · doi:10.1109/tai.2022.3208217 · Cited by 5
“A LARGE-SCALE infectious coronavirus outbreak in December 2019 [1] was announced by the World Health Organization as novel coronavirus pneumonia (COVID-19) [2] in February 2020.”
BackgroundBu, F., Guan, R., Wang, W., Liu, Z., Yin, S., Zhao, Y., & Chai, J. (2022) · Medicine · doi:10.1097/md.0000000000032100 · Cited by 4
“[54] Unfortunately, it cannot be supported by autopsy sample data from a large number of patients.”
BackgroundHamed, S. A. (2023) · World Journal of Otorhinolaryngology · doi:10.5319/wjo.v10.i2.4 · Cited by 3
Zhang, X., Sh, Y., Dong, J., Chen, Z., & Hong, F. (2023) · Theranostics · doi:10.7150/thno.83405 · Cited by 3
Impact of COVID-19 Infection on Work Functioning in Japanese Workers: A Prospective Cohort Study
Okawara, M., Hirashima, K., Igarashi, Y., Mafune, K., Muramatsu, K., Nagata, T., Tsuji, M., Ogami, A., Fujino, Y., Ogami, A., et al. (2023) · Safety and Health at Work · doi:10.1016/j.shaw.2023.10.004 · Cited by 3
“Evidence exists for central nervous system sequelae following SARS-CoV-2 infection [28,29].”
BackgroundLin, J., Zheng, D. M., Tian, D., Zheng, P., Zhang, H., Li, C., Lei, C., Shi, F., & Wang, H. (2024) · Molecular Neurobiology · doi:10.1007/s12035-024-04109-4 · Cited by 3
“These findings are consistent with previously reported studies [31, 32].”
Castañeyra-Perdomo, A., González–Mora, J. L., Carmona-Calero, E. M., Makris, N., & Carrasco-Juan, J. L. (2024) · American Journal of Forensic Medicine & Pathology · doi:10.1097/paf.0000000000000939 · Cited by 3
Latifi, A. (2025) · COVID · doi:10.3390/covid5020027 · Cited by 3
SARS-CoV-2 and interferon blockade
Diamond, B., Volpe, B. T., VanPatten, S., & Abed, Y. A. (2020) · Molecular Medicine · doi:10.1186/s10020-020-00231-w · Cited by 3
Manifestaciones extratorácicas de la COVID-19 en adultos y presentación de la enfermedad en niños
Plasencia-Martínez, J. M., Rovira, À., Domínguez, P. C., Barber, I., García‐Garrigós, E., & Arenas-Jiménez, J. J. (2021) · Radiología · doi:10.1016/j.rx.2021.03.005 · Cited by 3
Neuropsychiatrische Aspekte von COVID-19 – Eine narrative Übersicht
Rittmannsberger, H., Barth, M., Malik, P., & Yazdi, K. (2021) · Fortschritte der Neurologie · Psychiatrie · doi:10.1055/a-1523-3850 · Cited by 3
“Eine neuropathologische Untersuchung an den Gehirnen von 18 Verstorbenen fand bei der Mehrzahl der Patienten hypoxische Schä-den, keinen Hinweis auf Encephalitis und nur bei 5 Fällen war das Virus in geringer Intensität nachweisbar [20].”
BackgroundSaini, A., Oh, T. H., Ghanem, D. A., Castro, M., Butler, M., Lam, C. C. S. F., Posporelis, S., Lewis, G., David, A. S., & Rogers, J. P. (2021) · Aging & Mental Health · doi:10.1080/13607863.2021.1989375 · Cited by 3
“This is supported by autopsy data showing hypoxic brain damage in deceased COVID-19 patients (Kantonen et al., 2020; Reichard et al., 2020; Solomon et al., 2020).”
ResultNeurological manifestations in patients with new coronavirus infection COVID-19
Sсherbak, S. G., Голота, А. С., Kamilova, Т. A., Vologzhanin, D. A., & Макаренко, С. В. (2022) · Physical and rehabilitation medicine medical rehabilitation · doi:10.36425/rehab109952 · Cited by 3
“У пациентов с COVID наблюдаются острое гипоксическое повреждение головного мозга и мозжечка, потеря нейронов коры головного мозга, гиппокампа и мозжечкового слоя клеток Пуркинье с очагами периваскулярных лимфоцитов и очаговым лептоменингеальным воспалением [98].”
Yepes, M. (2022) · Current Drug Targets · doi:10.2174/1389450123666220919123029 · Cited by 4
Hutch, M. R., Son, J., Le, T. T., Hong, C., Wang, X., Abad, Z. S. H., Morris, M. M., Gutiérrez‐Sacristán, A., Klann, J. G., Spiridou, A., et al. (2024) · PLOS Digital Health · doi:10.1371/journal.pdig.0000484 · Cited by 3
Beach, T. G., Deture, M. A., Walker, J. E., Arce, R. A., Glass, M. J., Sue, L. I., Intorcia, A. J., Nelson, C. M., Suszczewicz, K. E., Borja, C. I., et al. (2021) · medRxiv · doi:10.1101/2021.12.16.21266656 · Cited by 3
Poor sensitivity of iPSC-derived neural progenitors and glutamatergic neurons to SARS-CoV-2Preprint
Zivaljic, M., Hubert, M., Grzelak, L., Sansone, G., Maskos, U., & Schwartz, O. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.07.25.501370 · Cited by 3
“Possible artifact RNA contamination was raised, given the challenge of dissecting the brain parenchyma from vasculature and meninges (Solomon et al., 2020).”
BackgroundInfluentialOn the plausibility of late neuropsychiatric manifestations associated with the COVID-19 pandemic
André, A., Félix, C., Corvacho, M., & Nzwalo, H. (2020) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2020.117060 · Cited by 2
“Very low levels of SARSCoV-2 was detected in very few patients who died from COVID-19 [14].”
InfluentialHypoxemia exerts detrimental effects on the choroid plexuses and cerebrospinal fluid system in rats
Barakat, R., Al‐Sarraf, H., & Redzic, Z. B. (2025) · Fluids and Barriers of the CNS · doi:10.1186/s12987-024-00613-w · Cited by 2
“Though hypoxic injury during severe hypoxemia as a cause of sABI is not disputable [7], it is probably not the only mechanism involved.”
Advancements in Epidemic Transmission Suppression: A Comprehensive Survey
Tong, L., Zhang, S., Sun, H., Cai, Y., Zhang, J., Qian, W., Zhang, Q., He, Q., Chen, J., & Li, J. (2025) · IEEE Transactions on Network Science and Engineering · doi:10.1109/tnse.2025.3579136 · Cited by 2
“Embargoes and restrictions imposed by States have led to business closures, reduced commercial activity, the collapse of the tourism industry, disruptions in global supply chains, a surge in unemployment and severe constraints on economic growth [8].”
Can the COVID-19 pandemic advance neuroinfectious research?
Duggan, M. R., Chatila, Z. K., Auber, L. A., Silberberg, E., Fernandez, J. R., Walker, K. A., & Schultek, N. M. (2025) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2025.106233 · Cited by 2
Stigliano, E., Tocci, A., Florio, R., Arena, V., & Amadoro, G. (2026) · Cells · doi:10.3390/cells15020176 · Cited by 2
Bianco, L. S., Nicoliche, T., Correa-Netto, N. F., Lanaro, R., Caetano, A. L., Prado, C. M., Ureshino, R. P., Tibério, I. D. F. L. C., Righetti, R. F., Stilhano, R. S., et al. (2026) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1703727 · Cited by 2
“…of Alzheimer’s disease and related dementias include microglial inflammation (Oliveira et al., 2023), ischemic changes associated with COVID-19 (Solomon et al., 2020), and endothelial damage, which may impair the clearance of brain metabolites, including beta-amyloid peptides involved in…”
Hussain, M., Platero-Portillo, T., Oni, O., Elzieny, M., Khera, K. M., Padharia, H., & Guevara, N. (2021) · EMJ Microbiology & Infectious Diseases · doi:10.33590/emjmicrobiolinfectdis/20-00195 · Cited by 2
Muerte cerebral debida a aspergilosis cerebral en un paciente de COVID-19
Videla, C., Agustina, M., Niveyro, P. X. D. L. I., & Nicolás, M. (2022) · Revista Española de Anestesiología y Reanimación · doi:10.1016/j.redar.2022.01.002 · Cited by 2
Aghdam, K. A., Abtahi, Z.-A., Sonbolestan, S. A., & Sanjari, M. S. (2022) · Journal of Current Ophthalmology · doi:10.4103/joco.joco_321_21 · Cited by 2
“, elevated interleukin‐6 in SARS-CoV-2 infection)9,10, (2) platelet destruction by the immune system activity (cross-reaction of antiviral antibodies with platelet integrin GP IIb/IIIa)11, and (3) platelet aggregation in the lungs as microthrombi and thrombi causing platelet consumption.”
BackgroundLidiia, S., Gavrilova, N., Ryabkova, V. A., Maria, L., & Kamaeva, E. (2023) · Elsevier eBooks · doi:10.1016/b978-0-443-18566-3.00027-x · Cited by 2
Rittmannsberger, H., Barth, M., Lamprecht, B., Malík, P., & Yazdi‐Zorn, K. (2023) · Neuropsychiatrie · doi:10.1007/s40211-023-00487-8 · Cited by 2
“Dabei wurden Verletzungen der Integrität der Blutgefäße mit Störung der BHS, Entzündungen der Gefäßwände, Mikroblutungen und -Thromben festgestellt [39, 43, 103–106], sowie hy-poxische Läsionen [39, 43, 105, 107] und axonale Schäden [105].”
Troxel, A. B., Bind, M., Flotte, T. J., Cordon‐Cardo, C., Decker, L. A., Finn, A. V., Padera, R. F., Reichard, R. R., Stone, J. R., Adolphi, N. L., et al. (2024) · PLoS ONE · doi:10.1371/journal.pone.0285645 · Cited by 2
Neuropsychiatric complications of coronavirus disease 2019: Mount Sinai Health System cohort study
Gururangan, K., Peschansky, V. J., Hyfte, G. V., Agarwal, P., Blank, L. J., Mathew, B., Goldstein, J. M., Kwon, C., McCarthy, L., Cohen, A., et al. (2024) · Journal of Neurology · doi:10.1007/s00415-024-12370-9 · Cited by 2
“However, initial neuropathological series were not supportive of direct neu-roinvasion (e.g., viral encephalitis) as the primary mechanism of neurological injury, but other mechanisms related to local and systemic parenchymal and vascular inflammation have been elucidated [46–49].”
Qureshi, N. A., & Alhabeeb, A. A. (2020) · International Neuropsychiatric Disease Journal · doi:10.9734/indj/2020/v14i430135 · Cited by 2
“Body systems and manifestations of COVID-19# [32-42]”
COVID-19 (novel SARS-CoV-2) neurological illness
Younger, D. S. (2023) · Handbook of clinical neurology · doi:10.1016/b978-0-323-98818-6.00014-5 · Cited by 2
McAlpine, L. S., Barden, M. M., Zubair, A. S., & Sanamandra, S. (2021) · Cureus · doi:10.7759/cureus.13277 · Cited by 2
“7 Other findings demonstrated in critically ill patients that could contribute to encephalopathy include bilateral frontotemporal hypoperfusion, leptomeningeal enhancement, and hypoxic changes on pathology [8,9].”
BackgroundTreatment and Management of Autoimmune Neuropathies
El-Abassi, R. N., Soliman, M. Y., Levy, M. H., & England, J. D. (2021) · Elsevier eBooks · doi:10.1016/b978-0-323-71317-7.00015-9 · Cited by 2
Features of nervous system damage in antiphospholipid syndrome
Voskresenskaya, O. N., Bitsadze, V. O., Khizroeva, J. K., Sukontseva, T. A., Tretyakova, M. V., Shkoda, A. S., Gris, J., Elalamy, I., Rizzo, G., Blinov, D. V., et al. (2021) · Obstetrics Gynecology and Reproduction · doi:10.17749/2313-7347/ob.gyn.rep.2021.242 · Cited by 2
“В обонятельных луковицах и трактах никаких микроскопических изменений замечено не было [52].”
Bombón-Albán, P. E., & Salazar, J. V. S. (2022) · Revista de Neuro-Psiquiatría · doi:10.20453/rnp.v85i2.4229 · Cited by 2
Chu, J. Y., Moe, G. W. P. L., Vyas, M. V., Chen, R. E., Chow, C.-M., Gupta, M., Kaliwal, Y., Koh, M., Ko, D. T., & Liu, P. P. (2022) · CJC Open · doi:10.1016/j.cjco.2022.06.008 · Cited by 2
“Such future studies would be vital in explaining why differences occur in neurologic and cardiac complications among various ethnic groups.(73)”
BackgroundBeltz, L. A. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-98809-4.00013-9 · Cited by 2
Sleep and Circadian Rhythm in Post-COVID-19 Patients
Mahmud, R. (2023) · Progress in Sleep Research · doi:10.1007/978-981-99-0240-8_12 · Cited by 2
Clinical surrogates of dysautonomia predict lethal outcome in COVID-19 on intensive care unit
Woo, M. S., Mayer, C., Fischer, M., Kluge, S., Roedl, K., Gerloff, C. P., Czorlich, P., Thomalla, G., Wiesch, J. S. Z., & Schweingruber, N. (2023) · Neurological Research and Practice · doi:10.1186/s42466-023-00243-x · Cited by 2
“Thus, SARS-CoV-2 RNA and nucleocapsid were detected in the brainstem and cranial nerves of deceased COVID19 patients [13, 14].”
BackgroundNeurorecovery after Critical COVID-19 Illness
Alabsi, H. S., Emerson, K., & Lin, D. J. (2023) · Seminars in Neurology · doi:10.1055/s-0043-1768714 · Cited by 2
Joint margin adaption and multiscale feature fusion for COVID-19 CT images segmentation
Chen, Y., Zhang, W., Zhou, T., Lin, H., Heidari, A. A., Chen, H., & Liu, L. (2024) · Biomedical Signal Processing and Control · doi:10.1016/j.bspc.2023.105912 · Cited by 2
Hanganu, A. R., Niculae, C., Dulămea, A. O., Moisă, E., Constantin, R., Neagu, G., & Hristea, A. (2024) · Frontiers in Neurology · doi:10.3389/fneur.2023.1338593 · Cited by 3
Magaki, S., Zhang, T., Han, K., Hilda, M., Yong, W. H., Achim, C. L., Fishbein, G. A., Fishbein, M. C., Garner, O. B., Salamon, N., et al. (2024) · Free Neuropathology · doi:10.17879/freeneuropathology-2024-5343 · Cited by 2
Fu, S., Li, J., Li, H., & Yang, J. (2024) · Scientific Reports · doi:10.1038/s41598-024-68930-6 · Cited by 2
Adaptation of advanced clinical virology assays from HIV-1 to SARS-CoV-2
McCormick, K. D., Mellors, J. W., & Jacobs, J. L. (2020) · Current Opinion in HIV and AIDS · doi:10.1097/coh.0000000000000656 · Cited by 2
Implicaciones en Neuroanestesia durante la pandemia por COVID-19
Santos, C. A. M.-D. L. (2021) · Archivos de Neurociencias · doi:10.31157/an.v26i4.293 · Cited by 2
Cognitive impairment in hospitalized patients with COVID-19
Петрович, Б. С., Tolmachev, K. D., Kriukova, K. K., Gurina, O. I., & Preobrazhenskaya, I. S. (2022) · Meditsinskiy sovet = Medical Council · doi:10.21518/2079-701x-2022-16-2-24-32 · Cited by 2
Battaglini, D., Santori, G., Chandraptham, K., Iannuzzi, F., Bastianello, M., Tarantino, F., Ball, L., Giacobbe, D. R., Vena, A., Bassetti, M., et al. (2020) · Research Square · doi:10.21203/rs.3.rs-57910/v1 · Cited by 2
“However, recent reports suggest that hypoxic-ischemic damage could be the main driver of neurological symptoms in COVID-19 patients (21).”
BackgroundCOVID-19-Associated Encephalopathy (COVEP): Basic Aspects of Neuropathology
Stoyanov, G. S., Stoyanov, D. S., Ivanov, M. N., Tonchev, A. B., Popov, H., & Petkova, L. (2022) · Encyclopedia · doi:10.3390/encyclopedia2040122 · Cited by 2
Neurological Factors and Gastrointestinal Health in Post-Acute COVID-19 Syndrome (PACS)
Mahedi, M., Islam, S. M. S., Jamali, M., Wei, C. R., Afrin, S., & Syrmos, N. C. (2024) · Asian Science Bulletin · doi:10.3923/asb.2024.112.122 · Cited by 1
Neuropathological Findings in the Brains of Deceased COVID-19 Patients
Shergill, A., Omalu, B. I., Conner, P., & Wilson, M. (2025) · American Journal of Forensic Medicine & Pathology · doi:10.1097/paf.0000000000001010 · Cited by 1
Balakrishnan, R., Subbarayan, R., Shrestha, R., & Chauhan, A. (2025) · Biochemical Genetics · doi:10.1007/s10528-025-11208-x · Cited by 1
“These shared genetic and molecular pathways suggest that COVID-19 may worsen or accelerate brain degeneration in individuals who are already at risk (Moriguchi et al. 2020; Paniz-Mondolfi et al. 2020; Solomon et al. 2020).”
Cai, H., Yan, G., & Pei, H. (2025) · Physica Scripta · doi:10.1088/1402-4896/ae1fb4 · Cited by 1
de Almeida, A. L. T., da Silva, A. M. V., Souza, M. M. E., Rodrigues, M. T., Coelho, F. S., da Rosa, L. C., Azamor, T., Várady, C. B. S., da Silva, B. J. D., de Almeida, A. C., et al. (2026) · Microorganisms · doi:10.3390/microorganisms14040852 · Cited by 1
“The death of neural cells has been observed in human cases of SARS-CoV-2 infection [67,68] and, in our ultrastructural analysis, the cellular damage was mostly characterized by the presence of pyknotic nuclei and cytoplasmic rarefaction.”
Human brain matters: Navigating the neuropathology of COVID ‐19
Nieuwland, J. M., Scaramuzza, A., Bugiani, M., van de Berg, W. D. J., & Middeldorp, J. (2026) · Brain Pathology · doi:10.1111/bpa.70101 · Cited by 2
“Vascular hypoxia was seen in fatal patients demonstrating middle and posterior arterial pathology, including neocortical infarcts, small hemorrhages, white matter lesions and vasculitis [132 – 134].”
Sheibani, M., Georgakopoulou, V., Mohammadi, M., Abdollahi, E., Khatir, Z. Z., & Valipour, M. (2026) · Medicine in Drug Discovery · doi:10.1016/j.medidd.2026.100257 · Cited by 1
Sarvilina, I. V., Громова, О. А., & Naumov, A. V. (2021) · Neurology neuropsychiatry Psychosomatics · doi:10.14412/2074-2711-2021-5-109-115 · Cited by 1
Клінічні прояви синдрому пост-COVID-19
Tronko, M. D., Orlenko, V. L., Kurinna, Y. V., & Ivaskiva, К. Y. (2021) · Endokrynologia · doi:10.31793/1680-1466.2021.26-3.248 · Cited by 2
Особливості вегетативних розладів у хворих на COVID-19
Vodopianov, V. A., Strelchenko, O. S., Malyshev, V. V., Krivonos, M. Y., Kosse, M. Y., & Demydenko, D. P. (2022) · INTERNATIONAL NEUROLOGICAL JOURNAL · doi:10.22141/2224-0713.17.8.2021.250820 · Cited by 1
Neurophysiological assessment of speech function in individuals having a history of mild COVID-19
Гуляев, С. А., Voronkova, Y., Abramova, T. A., & Ковражкина, Е. А. (2022) · Medicine of Extreme Situations · doi:10.47183/mes.2022.016 · Cited by 1
Kumar, H., & Gupta, R. (2022) · International Journal of Neuroscience · doi:10.1080/00207454.2022.2100784 · Cited by 1
Experimental Models of SARS-COV-2 Infection in the Central Nervous System
Paoletti, A. M., Melilli, M. G., & Vecchio, I. (2022) · Journal of Central Nervous System Disease · doi:10.1177/11795735221102231 · Cited by 1
“Histopathological examination of brain samples from COVID-19 patients revealed a neuronal loss in the cerebral cortex, hippocampus and cerebellar Purkinje cell layer.(58) These findings further support the hypothesis that COVID-19 could”
ResultCOVID-19 and Dementia; Hard to Forget Yet Haunting Forgetfulness!
Kaliappan, A., Archana Gaur, T., Sakthivadivel, V., Balan, Y., Tadi, L. J., & Sundaramurthy, R. (2022) · Annals of Indian Academy of Neurology · doi:10.4103/aian.aian_42_22 · Cited by 1
“Studies have also reported olfactory disturbances as the only presenting symptom in some cases of COVID‑19.”
BackgroundInfluentialCentral Nervous System Neuroimmunologic Complications of COVID-19
Holroyd, K. B., & Conway, S. E. (2023) · Seminars in Neurology · doi:10.1055/s-0043-1767713 · Cited by 1
Blood brain barrier disruption following COVID-19 infection and neurological manifestations
Deshwal, S., Dhiman, N., & Sandhir, R. (2023) · Elsevier eBooks · doi:10.1016/b978-0-443-15256-6.00005-2 · Cited by 1
Dynamic electroencephalographic study of persons – mild COVID-19 convalescents
Гуляев, С. А. (2023) · Russian Journal of Child Neurology · doi:10.17650/2073-8803-2022-17-4-44-53 · Cited by 1
Prevalence and risk factors for seizures in adult COVID-19 patients: A meta-analysis
Garção, D. C., Correia, A. G. D. S., Ferreira, F. J. S., Pereira, P. C., Fontes, L. R. G., & Ferreira, L. C. (2023) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2023.109501 · Cited by 1
Banerjee, M., Chadha, S., Sanyal, S., & Mukherjee, S. (2023) · Coronaviruses · doi:10.2174/0126667975269506231108053010 · Cited by 1
The neurological manifestations in children with COVID-19 infection
Mohsen, A. A. H., Kadhim, A. A. M., Hassan, H. S. M., Mosawy, J. M. H. A., & Nasrawi, A. J. M. (2024) · CHILD`S HEALTH · doi:10.22141/2224-0551.19.5.2024.1725 · Cited by 1
Cerebral malaria: Understanding the parasite pathogenesis in the brain
Moreira, E. T. D. S., Castro-Faria-Neto, H. C., & dos Reis, P. R. P. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-19130-5.00017-4 · Cited by 1
Du, S., Fang, L., Li, Y., Liu, S., Luo, X., Zeng, S., Zheng, S., Yang, H., Xu, Y. J., Li, D., et al. (2025) · Journal of Zhejiang University SCIENCE B · doi:10.1631/jzus.b2300831 · Cited by 1
“Several studies have in‐ dicated that this could be attributed to factors such as inflammation and inadequate oxygen supply (Muccioli et al., 2020; Solomon et al., 2020).”
Olfactory dysfunction may predict myocardial injury in COVID-19 patients
Akşıt, E., Çil, Ö. Ç., & Kaya, H. (2020) · Medical Hypotheses · doi:10.1016/j.mehy.2020.110232 · Cited by 1
“reported that there was no damage to olfactory bulbs or tracts of COVID-19 patients [3] whereas Torabi et al.”
Leslie-Mazwi, T. M., & Hirsch, J. A. (2020) · American Journal of Neuroradiology · doi:10.3174/ajnr.a6864 · Cited by 1
Winegarden, J. A., Carr, D. B., & Pike, V. (2020) · Palliative Medicine Reports · doi:10.1089/pmr.2020.0102 · Cited by 1
Síntomas Neurológicos por Covid-19, ¿en realidad son frecuentes?
Santos, C. A. M.-D. L., Manrique-Carmona, L. P., & Mejía-Mantilla, J. H. (2021) · Archivos de Neurociencias · doi:10.31157/archneurosciencesmex.v26i01.269 · Cited by 1
Cell perturbation in choroid plexus and cortex aiding COVID-19 neurological symptoms
Mao, X., & Jin, W. (2021) · 中国科学通报：英文版 · doi:10.1016/j.scib.2021.08.017 · Cited by 1
“[1] showed that there is an absence or a low level of viral RNA detected in some brain samples of COVID19, and the possibility of contamination has been raised as previously described [10].”
CEREBROVASCULAR COMPLICATIONS OF COVID-19
Lychko, V., & Burtyka, M. (2021) · Eastern Ukrainian Medical Journal · doi:10.21272/eumj.2021;9(3):219-227 · Cited by 1
„Dum spiro spero”: a SARS-CoV-2-fertőzés klinikopatológiája 26 eset kapcsán
Zombori, T., Kuthi, L., Hortobágyi, T., Csörgő, E., Árgyelán, J., Kocsis, L., Sejben, I., Kaizer, L., Radics, B., Sejben, A., et al. (2021) · Orvosi Hetilap · doi:10.1556/650.2021.32387 · Cited by 1
“Egyes szerzők enyhe, fokális agytörzsi gyulladást észleltek a károsodott, néha microthrombusokat is tartalmazó erek körül, illetve vizenyő mellett elszórtan bevérzett területeket figyeltek meg [29], míg mások nem láttak eltéréseket az agyban az esetleges hypoxia következményein kívül [30].”
BackgroundDiagnostic Approaches to Acute Neuro-COVID
Cascella, M., & Blasio, E. D. (2021) · Springer eBooks · doi:10.1007/978-3-030-86705-8_3 · Cited by 1
Mogensen, M. A., & Filippi, C. G. (2022) · Neuroimaging Clinics of North America · doi:10.1016/j.nic.2022.07.004 · Cited by 1
Multifactorial Effects of COVID-19: A Review of Published Autopsy Reports
Chawla, K., Hong, S., Shields, R., Ford, A., Pacella, G., & Lurie, F. (2022) · COVID · doi:10.3390/covid2050041 · Cited by 1
Starting signal: Aberrant kinase activation as a trigger for SARS-CoV-2 induced axonal damage
Richards, A. L., & Jaenisch, R. (2022) · Frontiers in Virology · doi:10.3389/fviro.2022.973997 · Cited by 1
“As noted in the previous section, SARS-CoV-2 infection of CNS neurons remains a rare outcome of infection (30).”
BackgroundNeurological Sequelae of COVID-19
Srivastava, M. V. P., & Agarwal, A. (2022) · Springer eBooks · doi:10.1007/978-981-19-4407-9_5 · Cited by 1
COVID-19 and the central nervous system: What is the interplay?
El‐Fadeal, N. M. A., Anber, S. A., Elkot, H. A., Maged, G., Saeed, I. A., Negm, M. M., Abdelsamad, M. A., El-bakri, A., & Mohamed, W. M. Y. (2022) · Neuroscience Research Notes · doi:10.31117/neuroscirn.v5i4.155 · Cited by 1
Neurological manifestations associated with SARS-CoV-2 infection: an updated review.
Macías, D. J. C., Vizcaíno, G., & Siteneski, A. (2023) · Investigación Clínica · doi:10.54817/ic.v64n1a08 · Cited by 2
“Curiously, a study evaluating 18 brains of patients who died 0 to 32 days after the onset of symptoms of COVID-19 in the histopathological analysis showed only hypoxic changes and did not show encephalitis or other specific brain changes referable to the infection 63 .”
Neurological Manifestations of COVID-19
Hepburn, M., Newey, C. R., & George, P. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-87539-4.00007-5 · Cited by 1
Rizk, M. Z., & Aly, H. F. (2021) · Egyptian Pharmaceutical Journal · doi:10.4103/epj.epj_36_21 · Cited by 1
Frontera, J. A., Lewis, A. K., Yaghi, S. R., & Bhimraj, A. (2021) · Neurology · doi:10.1212/wnl.0000000000012357 · Cited by 1
Neuropathology and Virus in Brain of SARS-CoV-2 Infected Non-Human PrimatesPreprint
Fischer, T., Rutkai, I., Mayer, M., Hellmers, L., Ning, B., Huang, Z. J., Monjure, C. J., Coyne, C., Silvestri, R., Golden, N., et al. (2020) · doi:10.21203/rs.3.rs-59871/v1 · Cited by 1
The landscape of human brain immune response in patients with severe COVID-19Preprint
Fullard, J., Lee, H.-C., Voloudakis, G., Suo, S.-B., Shao, Z., Peter, C., Javidfar, B., Zhang, W., Jiang, S., Corvelo, A., et al. (2021) · bioRxiv · doi:10.1101/2021.01.08.425999 · Cited by 1
Neuropathologic Findings of Patients with COVID-19: A Systematic ReviewPreprint
Pajo, A. T., Espiritu, A. I., Apor, A. D. A. O., & Jamora, R. D. G. (2020) · SSRN Electronic Journal · doi:10.2139/ssrn.3742286 · Cited by 1
Jain, A., Lamperti, M., & Doyle, D. J. (2021) · British Journal of Anaesthesia · doi:10.1016/j.bja.2021.10.031 · Cited by 1
“However, there is limited evidence of SARSCoV-2 infection of neurones, and brain autopsies of patients with COVID-19 show no neuronal infection.(2) Direct viral involvement of brain or olfactory nerves was limited to detecting low levels of viral RNA and rare viral antigens in cranial nerves and scattered brainstem ce…”
BackgroundSARS-CoV-2 causes brain inflammation via impaired neuro-immune interactionsPreprint
Oka, N., Shimada, K., Ishii, A., Kobayashi, N., & Kondo, K. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.07.13.499991 · Cited by 1
Natural Causes of Sudden Death
Turillazzi, E., Santurro, A., Ricci, P., Scopetti, M., & Fineschi, V. (2022) · Wiley eBooks · doi:10.1002/9781119648628.ch34 · Cited by 1
Gavrilova, N., Normatov, M. G., Soprun, L. A., Utekhin, V. J., Fedotkina, T. V., & Churilov, L. P. (2023) · Preprints.org · doi:10.20944/preprints202307.0489.v1 · Cited by 1
Colinet, M., Chiver, I., Bonafina, A., Masset, G., Almansa, D., Valentin, E. D., Twizere, J., Nguyen, L., & Espuny-Camacho, I. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.04.16.589036 · Cited by 1
ACE2-expressing endothelial cells in aging mouse brainPreprint
Lim, S. B., Dawson, V. L., Dawson, T. M., & Kang, S.-U. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.07.11.198770
“COVID-19 patients [12,13], other lines of evidence support the neurotropism of the virus, as evidenced by experimental platforms leveraging human induced pluripotent stem cell (iPSC)derived dopaminergic neurons [22] and an organotypic brain model [23].”
BackgroundResultNeurology and Covid-19: Present and Future
Ramos, F. J. H., Hernández Chamorro, F. J., García, A. P., & Hernández, J. (2020) · International Journal of Innovative Research in Medical Science · doi:10.23958/ijirms/vol05-i10/946
“A recent neuropathologic study with 18 Covid-19 patients [30], shows that the primal changes are caused by hypoxia and that there are no viral particles in those brains.”
BackgroundNeuropathologische Veränderungen bei COVID-19
Matschke, J., Hagel, C., & Glatzel, M. (2020) · Der Klinikarzt · doi:10.1055/a-1261-8758
“Eine ausgeprägte Enzephalitis ist kein typisches neuropathologisches Merkmal von COVID-19 [12, 15].”
Background
Metadata
- Authors
- Solomon, I. H., Normandin, E., Bhattacharyya, S., Mukerji, S. S., Keller, K., Ali, A. S., Adams, G., Hornick, J. L., Padera, R. F., & Sabeti, P.
- Affiliations
- Brigham and Women's Hospital (US)
- Broad Institute (US)
- Massachusetts General Hospital (US)
- Corresponding author
- Solomon, Isaac H.
- ORCID
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2020-09-03
- Volume
- 383
- Issue
- 10
- Pages
- 989-992
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- PMC
- PMC7304421
- OpenAlex
- W3035063822
- Cited by
- 815
- References
- 3
- Citations by year
- 2026: 15 · 2025: 32 · 2024: 75 · 2023: 119 · 2022: 164 · 2021: 267 · 2020: 143
- FWCI
- 75.89
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Howard Hughes Medical Institute
- National Institute of Mental Health (K23MH115812)
- National Institute of Allergy and Infectious Diseases (U19AI110818)
- Topics
- Health Sciences › Medicine › Clinical Neurology › Long-Term Effects of COVID-19
- Health Sciences › Medicine › Infectious Diseases › Infectious Encephalopathies and Encephalitis
- Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
- Keywords
- COVID-19 pandemic, SARS-CoV-2, neuropathology, brain autopsy, encephalopathy
- MeSH terms
- Betacoronavirus, COVID-19, SARS-CoV-2, Aged, Autopsy, Brain, Female, Humans, Male, Middle Aged, Pneumonia, Viral, Coronavirus Infections, Pandemics
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
