The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Neuropathological Features of Covid-19
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Brain Autopsy Series in Patients with Covid-19 Eighteen brains of patients who died 0 to 32 days after the onset of symptoms of SARS-CoV-2 infection showed hypoxic–ischemic changes but no encephali...
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“a study carried out on the brains of 18 adults between the ages of 53 and 75 fallen victim to the virus revealed neither CT-informed macrostructural abnormalities, nor microstructural damage ascribable to the virus, but only mild hypoxia-related modifications with, importantly, limited evidence of viral presence in the brain (34).”
From The impact of COVID-19 infection and enforced prolonged social isolation on neuropsychiatric symptoms in older adults with and without dementia: A review (2020) · cites this paper as [34]
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Cites
Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China
Mao, L., Jin, H., Wang, M., Hu, Y., Chen, S., He, Q., Chang, J., Hong, C., Zhou, Y., Wang, D., et al. (2020) · JAMA Neurology · doi:10.1001/jamaneurol.2020.1127 · Cited by 7,166
Lechien, J. R., Chiesa-Estomba, C. M., De Siati, D. R., Horoi, M., Le Bon, S. D., Rodriguez, A., Dequanter, D., Blecic, S., El Afia, F., Distinguin, L., et al. (2020) · European Archives of Oto-Rhino-Laryngology · doi:10.1007/s00405-020-05965-1 · Cited by 2,668
Giacomelli, A., Pezzati, L., Conti, F., Bernacchia, D., Siano, M., Oreni, L., Rusconi, S., Gervasoni, C., Ridolfo, A. L., Rizzardini, G., et al. (2020) · Clinical Infectious Diseases · doi:10.1093/cid/ciaa330 · Cited by 1,326
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Su, W., Ju, J., Gu, M., Wang, X., Liu, S., Yu, J., & Mu, D. (2023) · Figshare · doi:10.6084/m9.figshare.22790546
Fullard, J. F., Lee, H.-C., Voloudakis, G., Suo, S., Javidfar, B., Shao, Z., Peter, C. J., Zhang, W., Jiang, S., Corvelo, A., et al. (2021) · Figshare · doi:10.6084/m9.figshare.15020393
Torices, S., Cabrera, R., Stangis, M., Naranjo, O., Fattakhov, N. S., Téglás, T., Adesse, D., & Toborek, M. J. (2021) · Figshare · doi:10.6084/m9.figshare.15080318
Su, W., Ju, J., Gu, M., Wang, X., 刘少壮, Yu, J., & Mu, D. (2023) · Figshare · doi:10.6084/m9.figshare.22790543
Su, W., Ju, J., Gu, M., Wang, X., Liu, S., Yu, J., & Mu, D. (2023) · Figshare · doi:10.6084/m9.figshare.22790540
Li, R., Liu, G., Zhang, X., Zhang, M., Lu, J., & Li, H. (2024) · Figshare · doi:10.6084/m9.figshare.26609304
Post-COVID syndrome in patients after COVID-19‑associated stroke
Tushova, K. A., Nozdryukhina, N. V., & Kabaeva, E. N. (2025) · Vestnik nevrologii psihiatrii i nejrohirurgii (Bulletin of Neurology Psychiatry and Neurosurgery) · doi:10.33920/med-01-2511-01
Neurological Damages in COVID-19 Patients
Esmaeilzadeh, A., Maleki, A. J., Moradi, A., Ebrahimi, F., Nazari, M., Siahmansouri, A., Esmaeilzadeh, K., Bazargan, M., & Rahgosha, B. K. (2025) · Medical virology · doi:10.1007/978-981-95-1426-7_20
ApoE and COVID-19 Risk and Long-Term Burden
Tavares-Júnior, J. W. L., Ciurleo, G. C. V., Oriá, R. B., & Braga‐Neto, P. (2025) · Springer eBooks · doi:10.1007/978-3-031-52641-1_56-1
Rosiak, M., Clever, S., Leitzen, E., Beythien, G., Michaely, L. M., Lockow, S., Allnoch, L., Ciurkiewicz, M., zu Natrup, C. M., Tuchel, T., et al. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1788665
“In addition, there is circumstantial evidence for the presence of SARS-CoV-2 in the brain of infected individuals (10 – 13).”
SARS-CoV-2 and neurological disorders
Zivaljic, M. (2022) · theses.fr (ABES) · doi:10.70675/3feed643z6732z4fbdzba74z397a36fc61d6
Impact fonctionnel à court et long terme d'une infection au SARS-Cov2
Rapin, A. (2023) · theses.fr (ABES) · doi:10.70675/8d753f8bz2690z4cc2z8f01zb81c3647d0b5
Alzheimer's disease and related dementias (ADRD) after COVID‐19 infection: trends and disparities
Gupta, S., Simon, K. I., & Perry, B. L. (2026) · Alzheimer s & Dementia Behavior & Socioeconomics of Aging · doi:10.1002/bsa3.70084
Histopathological changes in the olfactory pathway in COVID-19: An autopsy-based case–control study
Doğan, M., Buğra, A., Kirkik, D., Kara, E., Ziyade, N., Büyük, Y., & Orhan, K. S. (2026) · Irish Journal of Medical Science (1971 -) · doi:10.1007/s11845-026-04450-8
ApoE and COVID-19 Risk and Long-Term Burden
Tavares-Júnior, J. W. L., Ciurleo, G. C. V., Oriá, R. B., & Braga‐Neto, P. (2026) · Springer eBooks · doi:10.1007/978-3-031-96089-5_56
Schlaepfer, J., Neck, S. D., Penrice-Randal, R., Sharma, P., Kirby, A., Tatham, L. M., Toledo, E. G., Herriott, J., Kijak, E., Sharp, J., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.05.27.728081
“While direct viral neuroinvasion has been demonstrated in severe human cases and animal models ( 13, 20, 21 ), the extent to which it contributes to Long-COVID neurological symptoms remains debated ( 61, 62 ).”
Asgarian, F. S., Bayat, S., & Khorasanizadeh, M. (2026) · مجله دانشگاه علوم پزشکی اراک · doi:10.66224/jams.28.6.519
Li, D., Shang, C., Li, Y., Zhao, R., Zhang, C., Li, N., Jin, N., Fan, S., Ma, C., Wang, Z., et al. (2026) · Comprehensive physiology · doi:10.1002/cph4.70222
“…have detected low levels of SARS- CoV-2 RNA in the cerebrospinal fluid (CSF) of patients with encephalitis, while multiple autopsy analyses have not detected the virus in the brain, even though there is evidence of CSF inflammation (Solomon et al. 2020; Reinhold et al. 2023; Ye et al. 2020).”
Wang, Q., Zhou, Y., Ding, T., Sun, Y., Yang, Y., Wu, Y., Liu, J., Lu, S., & Yang, J. (2026) · MedComm · doi:10.1002/mco2.70906
Convergent Innate Immune and Metabolic Signatures in Parkinson’s Disease and Viral InfectionPreprint
Belyea, M. M., Shafiq, M., Laß, J., Much, C., Liu, Z., Kruse, N., Haendler, K., Sreenivasan, V., Gelpí, E., Siebels, B., et al. (2026) · medRxiv · doi:10.64898/2026.08.28.26361092
Freitas, N. L., Gomes, Y. C. P., Nogueira, F. C. S., Echevarria‐Lima, J., Deus, J. V. C., Brandão, C. O., Soares, C., Silva, M. T. T., & Espíndola, O. D. M. (2026) · Journal of Medical Virology · doi:10.1002/jmv.71165
Impact of COVID-19 on Cognitive and Way to Resolve
Mohammad, A. R., & Nabidur, R. (2021) · International Journal of Coronaviruses · doi:10.14302/issn.2692-1537.ijcv-21-4007
Metadata
- Authors
- Solomon, I. H., Normandin, E., Bhattacharyya, S., Mukerji, S. S., Keller, K., Ali, A. S., Adams, G., Hornick, J. L., Padera, R. F., & Sabeti, P.
- Affiliations
- Brigham and Women's Hospital (US)
- Broad Institute (US)
- Massachusetts General Hospital (US)
- Corresponding author
- Solomon, Isaac H.
- ORCID
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2020-09-03
- Volume
- 383
- Issue
- 10
- Pages
- 989-992
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- PMC
- PMC7304421
- OpenAlex
- W3035063822
- Cited by
- 815
- References
- 3
- Citations by year
- 2026: 15 · 2025: 32 · 2024: 75 · 2023: 119 · 2022: 164 · 2021: 267 · 2020: 143
- FWCI
- 75.89
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Howard Hughes Medical Institute
- National Institute of Mental Health (K23MH115812)
- National Institute of Allergy and Infectious Diseases (U19AI110818)
- Topics
- Health Sciences › Medicine › Clinical Neurology › Long-Term Effects of COVID-19
- Health Sciences › Medicine › Infectious Diseases › Infectious Encephalopathies and Encephalitis
- Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
- Keywords
- COVID-19 pandemic, SARS-CoV-2, neuropathology, brain autopsy, encephalopathy
- MeSH terms
- Betacoronavirus, COVID-19, SARS-CoV-2, Aged, Autopsy, Brain, Female, Humans, Male, Middle Aged, Pneumonia, Viral, Coronavirus Infections, Pandemics
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