Cited by 2,122Gestational Diabetes Research and ManagementDiabetes Management and ResearchPregnancy and Medication Impact

The DOI matches its Crossref record; 37 of the 38 references it cites were found in a registry or an index; 11 of the 27 sources its claims cite were checked for support.

A Multicenter, Randomized Trial of Treatment for Mild Gestational Diabetes

Open access

Abstract

BACKGROUND: It is uncertain whether treatment of mild gestational diabetes mellitus improves pregnancy outcomes. METHODS: Women who were in the 24th to 31st week of gestation and who met the criteria for mild gestational diabetes mellitus (i.e., an abnormal result on an oral glucose-tolerance test but a fasting glucose level below 95 mg per deciliter [5.3 mmol per liter]) were randomly assigned to usual prenatal care (control group) or dietary intervention, self-monitoring of blood glucose, and insulin therapy, if necessary (treatment group). The primary outcome was a composite of stillbirth or perinatal death and neonatal complications, including hyperbilirubinemia, hypoglycemia, hyperinsulinemia, and birth trauma. RESULTS: A total of 958 women were randomly assigned to a study group--485 to the treatment group and 473 to the control group. We observed no significant difference between groups in the frequency of the composite outcome (32.4% and 37.0% in the treatment and control groups, respectively; P=0.14). There were no perinatal deaths. However, there were significant reductions with treatment as compared with usual care in several prespecified secondary outcomes, including mean birth weight (3302 vs. 3408 g), neonatal fat mass (427 vs. 464 g), the frequency of large-for-gestational-age infants (7.1% vs. 14.5%), birth weight greater than 4000 g (5.9% vs. 14.3%), shoulder dystocia (1.5% vs. 4.0%), and cesarean delivery (26.9% vs. 33.8%). Treatment of gestational diabetes mellitus, as compared with usual care, was also associated with reduced rates of preeclampsia and gestational hypertension (combined rates for the two conditions, 8.6% vs. 13.6%; P=0.01). CONCLUSIONS: Although treatment of mild gestational diabetes mellitus did not significantly reduce the frequency of a composite outcome that included stillbirth or perinatal death and several neonatal complications, it did reduce the risks of fetal overgrowth, shoulder dystocia, cesarean delivery, and hypertensive disorders. (ClinicalTrials.gov number, NCT00069576.)

Overview

Integrity signals

Registry

Crossref · 10.1056/nejmoa0902430

Cites

37 of 37 references verified0 citation errors · 0 not checkable

Statistics

Nothing to recompute.

Verification

Claims the paper makes

11 of 27 cited sources checked · 6 supported · 0 flagged · accuracy not yet measured

Show all 38 claims

  • Probably not a substantial claim. 12
  • It may state two separate claims as one. 12
  • The quote only partly states this claim. 1
21 of 21

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

Each contradiction between two passages listed here was confirmed by an independent check.

  • Birth-weight cutoff differs between methods and results

    Minor

    The prespecified outcome excludes infants weighing exactly 4000 g, but the results describe an outcome that includes them. The text does not establish which cutoff was used for the reported comparison.

  • Birth-weight threshold changes at exactly 4000 g

    Minor

    The prespecified outcome excludes infants weighing exactly 4000 g, but the results describe the outcome as including them. The two definitions classify infants at that weight differently.

2 of 2

Cited works that were retracted

Works this paper cites that were later retracted, from the retraction notices publishers deposit. Major when the notice came out before this paper was published.

  • Cites a retracted work: W4300627291

    Info

    The cited work was retracted; the date of the notice is not on record.

    Cited work W4300627291 · retraction date not known · this paper published 2009-10

1 of 1

Citations

Cites

2 retracted

Flagged first, then by citations

Show all 38 references

1 of the 38 references couldn’t be matched to a known paper.

Research works printed but not linked: 5

  1. O'Sullivan JB, 1964, Diabetes, 13, 278
  2. Metzger BE, 1998, Diabetes Care, 21, B161
  3. Cowett RM. Hypoglycemia and hyperglycemia in the newborn. In: Polin RA, Fox WW, eds. Fetal and neonatal physiology. Philadelphia: W.B. Saunders, 1992:406.
  4. McFarland LV, 1986, Obstet Gynecol, 68, 784
  5. Cousins L. Obstetric complications in diabetic pregnancies. In: Reece EA, Coustan DR, Gabbe SG, eds. Diabetes in women: adolescence, pregnancy, and menopause. 3rd ed. Philadelphia: Lippincott Williams & Wilkins, 2004:351-70.

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Metadata

Authors
Landon, M. B., Spong, C. Y., Thom, E., Carpenter, M. W., Ramin, S. M., Casey, B., Wapner, R. J., Varner, M. W., Rouse, D. J., Thorp, J. M., Sciscione, A., Catalano, P., Harper, M., Saade, G., Lain, K. Y., Sorokin, Y., Peaceman, A. M., Tolosa, J. E., & Anderson, G. B.
Affiliations
  • The Ohio State University (US)
  • Eunice Kennedy Shriver National Institute of Child Health and Human Development (US)
  • George Washington University (US)
  • Brown University (US)
  • The University of Texas Health Science Center at Houston (US)
  • The University of Texas Southwestern Medical Center (US)
  • Columbia University (US)
  • University of Utah (US)
  • University of Alabama at Birmingham (US)
  • Drexel University (US)
  • Case Western Reserve University (US)
  • Wake Forest University Health Sciences (US)
  • The University of Texas Medical Branch at Galveston (US)
  • University of Pittsburgh (US)
  • Wayne State University (US)
  • Northwestern University (US)
  • Oregon Health & Science University (US)
Venue
New England Journal of Medicine
Published
2009-10
Volume
361
Issue
14
Pages
1339-1348
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
OpenAlex
W2000357287
Cited by
2,122
References
38
Citations by year
2026: 97 · 2025: 102 · 2024: 109 · 2023: 109 · 2022: 118 · 2021: 145 · 2020: 150 · 2019: 131 · 2018: 153 · 2017: 122 · 2016: 123 · 2015: 127 · 2014: 133 · 2013: 119 · 2012: 121
FWCI
145.83
Type
journal article
Language
en
Open access
Locations
  • New England Journal of Medicine (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • National Institutes of Health (2r24hd050924-06)
  • National Center for Research Resources (C06RR011234, M01RR000080, UL1RR024989, UL1RR025755, UL1RR025764, M01RR000034)
  • Eunice Kennedy Shriver National Institute of Child Health and Human Development (HD40512, HD53118, U01HD036801, R24 HD-050924, HD27917, U10HD040544, U10HD034208, HD-27915, U10HD040512, HD34116, UG1HD034116, HD40545, HD34136, (HD40500, UG1HD053097, U10HD027915, U10HD040545, U10HD040560, HD 40544, HD-27860, HD40560, HD53097, U10HD027917, U10HD036801, U10HD027860, U10HD021410, HD 34208, HD 36801, U10HD053097, U10HD034116, HD27869, [HD21410, U10HD040500, U10HD040485, U10HD053118, U10HD027869, U10HD034136, UG1HD034208, U24HD036801, UG1HD040500, UG1HD040512, UG1HD027869, UG1HD040544, UG1HD040485, UG1HD027915, UG1HD040560, UG1HD040545, HD 40485)
Topics
  • Health Sciences › Medicine › Obstetrics and Gynecology › Gestational Diabetes Research and Management
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Pregnancy and Medication Impact
Keywords
gestational diabetes mellitus, dietary intervention, self-monitoring of blood glucose, insulin therapy, perinatal outcomes, stillbirth, neonatal complications, birth weight, large for gestational age, shoulder dystocia, cesarean section, preeclampsia, gestational hypertension, fetal overgrowth
MeSH terms
Adult, Birth Weight, Cesarean Section, Combined Modality Therapy, Female, Fetal Macrosomia, Glucose Tolerance Test, Humans, Hypoglycemic Agents, Infant, Newborn, Infant, Newborn, Diseases, Insulin, Pregnancy, Pregnancy Outcome, Body Mass Index, Diabetes, Gestational, Premature Birth, Stillbirth, Perinatal Mortality

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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

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Cited sources are checked with a language model’s help (gpt-6-sol).

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