The DOI matches its Crossref record; 22 of the 23 references it cites were found in a registry or an index.
Less-Tight versus Tight Control of Hypertension in Pregnancy
Open accessAbstract
BACKGROUND: The effects of less-tight versus tight control of hypertension on pregnancy complications are unclear. METHODS: We performed an open, international, multicenter trial involving women at 14 weeks 0 days to 33 weeks 6 days of gestation who had nonproteinuric preexisting or gestational hypertension, office diastolic blood pressure of 90 to 105 mm Hg (or 85 to 105 mm Hg if the woman was taking antihypertensive medications), and a live fetus. Women were randomly assigned to less-tight control (target diastolic blood pressure, 100 mm Hg) or tight control (target diastolic blood pressure, 85 mm Hg). The composite primary outcome was pregnancy loss or high-level neonatal care for more than 48 hours during the first 28 postnatal days. The secondary outcome was serious maternal complications occurring up to 6 weeks post partum or until hospital discharge, whichever was later. RESULTS: Included in the analysis were 987 women; 74.6% had preexisting hypertension. The primary-outcome rates were similar among 493 women assigned to less-tight control and 488 women assigned to tight control (31.4% and 30.7%, respectively; adjusted odds ratio, 1.02; 95% confidence interval [CI], 0.77 to 1.35), as were the rates of serious maternal complications (3.7% and 2.0%, respectively; adjusted odds ratio, 1.74; 95% CI, 0.79 to 3.84), despite a mean diastolic blood pressure that was higher in the less-tight-control group by 4.6 mm Hg (95% CI, 3.7 to 5.4). Severe hypertension (≥160/110 mm Hg) developed in 40.6% of the women in the less-tight-control group and 27.5% of the women in the tight-control group (P<0.001). CONCLUSIONS: We found no significant between-group differences in the risk of pregnancy loss, high-level neonatal care, or overall maternal complications, although less-tight control was associated with a significantly higher frequency of severe maternal hypertension. (Funded by the Canadian Institutes of Health Research; CHIPS Current Controlled Trials number, ISRCTN71416914; ClinicalTrials.gov number, NCT01192412.).
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Data from the previously published Control of Hypertension in Pregnancy Study (CHIPS) supports a target blood pressure goal of 110-135/85 mmHg to reduce the risk of uncontrolled maternal hypertension and minimize impaired fetal growth (125-127).”
From 15. Management of Diabetes in Pregnancy: Standards of Care in Diabetes—2024 (2024) · cites this paper as [126]
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“The 2015 study (126) excluded pregnancies complicated by preexisting diabetes, and only 6% of participants had GDM at enrollment.”
From 15. Management of Diabetes in Pregnancy: Standards of Care in Diabetes—2024 (2024) · cites this paper as [126]
The cited source says what the claim attributes to it.
In the citing paper
“There was no difference in pregnancy loss, neonatal care, or other neonatal outcomes between the groups with tighter versus less tight control of hypertension (126).”
From 15. Management of Diabetes in Pregnancy: Standards of Care in Diabetes—2024 (2024) · cites this paper as [126]
The cited source says what the claim attributes to it.
In the citing paper
“In CHIPS, aiming for a diastolic blood pressure of 85 mmHg during pregnancy was associated with reduced likelihood of developing accelerated maternal hypertension and no demonstrable adverse outcome for infants compared with aiming for a higher diastolic blood pressure.”
From 10. Cardiovascular Disease and Risk Management: Standards of Care in Diabetes—2025 (2025) · cites this paper as [53]
In the citing paper
“The mean systolic blood pressure achieved in the more intensively treated group was 133.1 ± 0.5 mmHg, and the mean diastolic blood pressure achieved in that group was 85.3 ± 0.3 mmHg.”
From 10. Cardiovascular Disease and Risk Management: Standards of Care in Diabetes—2023 (2023) · cites this paper as [46]
In the citing paper
“In CHIPS, targeting a diastolic blood pressure of 85 mmHg during pregnancy was associated with reduced likelihood of developing accelerated maternal hypertension and no demonstrable adverse outcome for infants compared with targeting a higher diastolic blood pressure.”
From 10. Cardiovascular Disease and Risk Management: Standards of Care in Diabetes—2023 (2023) · cites this paper as [46]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
(2013) · doi:10.1097/01.aog.0000437382.03963.88 · Cited by 3,961
Saving Mothers’ Lives: Reviewing maternal deaths to make motherhood safer: 2006–2008
Cantwell, R., Clutton-Brock, T. H., COOPER, G. M., Dawson, A. H., Drife, J., Garrod, D., Harper, A., Hulbert, D., Lucas, S. B., McClure, J. H., et al. (2011) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.2010.02847.x · Cited by 3,047
Steegers, E. A., von Dadelszen, P., Duvekot, J. J., & Pijnenborg, R. (2010) · The Lancet · doi:10.1016/s0140-6736(10)60279-6 · Cited by 2,850
A New and Improved Population-Based Canadian Reference for Birth Weight for Gestational Age
Kramer, M. S., Platt, R. W., Wen, S. W., Joseph, K. S., Allen, A. C., Abrahamowicz, M., Blondel, B., Bréart, G., & Bréart, G. (2001) · PEDIATRICS · doi:10.1542/peds.108.2.e35 · Cited by 1,526
Antihypertensive drug therapy for mild to moderate hypertension during pregnancy
Abalos, E., Duley, L., & Steyn, D. W. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002252.pub3 · Cited by 705
Diagnosis, Evaluation, and Management of the Hypertensive Disorders of Pregnancy: Executive Summary
Magee, L. A., Pels, A., Helewa, M. E., Rey, É., von Dadelszen, P., Magee, L. A., Audibert, F., Bujold, E., Côté, A., Douglas, M. J., et al. (2014) · Journal of Obstetrics and Gynaecology Canada · doi:10.1016/s1701-2163(15)30588-0 · Cited by 684
Self-citationvon Dadelszen, P., Payne, B. A., Li, J., Ansermino, J. M., Pipkin, F. B., Côté, A., Douglas, M. J., Gruslin, A., Hutcheon, J. A., Joseph, K. S., et al. (2010) · The Lancet · doi:10.1016/s0140-6736(10)61351-7 · Cited by 593
Self-citationRETIRED: Diagnosis, Evaluation, and Management of the Hypertensive Disorders of Pregnancy
Magee, L. A., Helewa, M. E., Rey, É., Cardew, S., Côté, A., Douglas, M. J., Firoz, T., Gibson, P., Gruslin, A., Lange, I. R., et al. (2008) · Journal of Obstetrics and Gynaecology Canada · doi:10.1016/s1701-2163(16)32776-1 · Cited by 581
Self-citationvon Dadelszen, P., Ornstein, M. P., Bull, S., Logan, A. G., Koren, G., & Magee, L. A. (2000) · The Lancet · doi:10.1016/s0140-6736(98)08049-0 · Cited by 509
Self-citationStroke and Severe Preeclampsia and Eclampsia: A Paradigm Shift Focusing on Systolic Blood Pressure
Martin, J. N., Jr., Thigpen, B. D., Moore, R., Rose, C. H., Cushman, J., & May, W. (2005) · Obstetrics and Gynecology · doi:10.1097/01.aog.0000151116.84113.56 · Cited by 504
Flagged first, then by citations
1 of the 23 references couldn’t be matched to a known paper.
Research works printed but not linked: 3
- Abalos E, 2014, Cochrane Database Syst Rev, 2, CD002252
- Magee LA, 2003, Cochrane Database Syst Rev, CD002863
- Arguedas JA, 2009, Cochrane Database Syst Rev, CD004349
Cited by
Sorted by citations
Whelton, P. K., Carey, R. M., Aronow, W. S., Casey, D. E., Collins, K. J., Dennison Himmelfarb, C., DePalma, S. M., Gidding, S., Jamerson, K. A., Jones, D. W., et al. (2018) · Hypertension · doi:10.1161/hyp.0000000000000065 · Cited by 7,391
Whelton, P. K., Carey, R. M., Aronow, W. S., Casey, D. E., Collins, K. J., Dennison Himmelfarb, C., DePalma, S. M., Gidding, S., Jamerson, K. A., Jones, D. W., et al. (2018) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.11.006 · Cited by 6,616
Mancia, G., Kreutz, R., Brunström, M., Burnier, M., Grassi, G., Januszewicz, A., Muiesan, M. L., Tsioufis, K., Agabiti-Rosei, E., Algharably, E. A. E., et al. (2023) · Journal of Hypertension · doi:10.1097/hjh.0000000000003480 · Cited by 3,473
2024 ESC Guidelines for the management of elevated blood pressure and hypertension
McEvoy, J. W., McCarthy, C. P., Bruno, R. M., Brouwers, S., Canavan, M. D., Ceconi, C., Christodorescu, R. M., Daskalopoulou, S. S., Ferro, C. J., Gerdts, E., et al. (2024) · European Heart Journal · doi:10.1093/eurheartj/ehae178 · Cited by 2,298
2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy
Regitz-Zagrosek, V., Roos-Hesselink, J. W., Bauersachs, J., Blomström-Lundqvist, C., Cífková, R., De Bonis, M., Iung, B., Johnson, M. R., Kintscher, U., Kranke, P., et al. (2018) · European Heart Journal · doi:10.1093/eurheartj/ehy340 · Cited by 2,292
Rana (2019) · doi:10.1161/circresaha.118.313276 · Cited by 2,095
Brown, M. A., Magee, L. A., Kenny, L. C., Karumanchi, S. A., McCarthy, F. P., Saito, S., Hall, D. R., Warren, C. E., Adoyi, G., & Ishaku, S. (2018) · Hypertension · doi:10.1161/hypertensionaha.117.10803 · Cited by 2,089
Self-citationThe Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2019)
Umemura, S., Arima, H., Arima, S., Asayama, K., Dohi, Y., Hirooka, Y., Horio, T., Hoshide, S., Ikeda, S., Ishimitsu, T., et al. (2019) · Hypertension Research · doi:10.1038/s41440-019-0284-9 · Cited by 1,880
Mol, B. W., Roberts, C. T., Thangaratinam, S., Magee, L. A., de Groot, C. J. M., & Hofmeyr, G. J. (2015) · The Lancet · doi:10.1016/s0140-6736(15)00070-7 · Cited by 1,667
Self-citationPractice Bulletin No. 183: postpartum hemorrhage
(2017) · Obstetrics & Gynecology · doi:10.1097/aog.0000000000002351 · Cited by 1,406
Diretrizes Brasileiras de Hipertensão Arterial – 2020
Barroso, W. K. S., Rodrigues, C. I. S., Bortolotto, L. A., Gomes, M. A. M., Brandão, A. A., Feitosa, A. D. M., Machado, C. A., Poli‐de‐Figueiredo, C. E., Amodeo, C., Mion, D., et al. (2021) · Arquivos Brasileiros de Cardiologia · doi:10.36660/abc.20201238 · Cited by 1,389
Magee, L. A., Brown, M. A., Hall, D. R., Gupte, S., Hennessy, A., Karumanchi, S. A., Kenny, L. C., McCarthy, F., Myers, J., Poon, L. C., et al. (2022) · Pregnancy Hypertension · doi:10.1016/j.preghy.2021.09.008 · Cited by 1,134
Self-citationWhelton, P. K., Carey, R. M., Aronow, W. S., Casey, D. E., Collins, K. J., Dennison Himmelfarb, C., DePalma, S. M., Gidding, S., Jamerson, K. A., Jones, D. W., et al. (2018) · Circulation · doi:10.1161/cir.0000000000000596 · Cited by 1,127
Brown, M. A., Magee, L. A., Kenny, L. C., Karumanchi, S. A., McCarthy, F. P., Saito, S., Hall, D. R., Warren, C., Adoyi, G., & Ishaku, S. (2018) · Pregnancy Hypertension · doi:10.1016/j.preghy.2018.05.004 · Cited by 1,117
Self-citationDimitriadis, E., Rolnik, D. L., Zhou, W., Estrada‐Gutiérrez, G., Koga, K., Francisco, R. P. V., Whitehead, C. L., Hyett, J. A., Costa, F. D. S., Nicolaides, K. H., et al. (2023) · Nature Reviews Disease Primers · doi:10.1038/s41572-023-00417-6 · Cited by 1,082
Chappell, L. C., Cluver, C. A., Kingdom, J. C., & Tong, S. (2021) · The Lancet · doi:10.1016/s0140-6736(20)32335-7 · Cited by 1,013
ACOG Practice Bulletin No. 203: Chronic Hypertension in Pregnancy
(2019) · Obstetrics & Gynecology · doi:10.1097/aog.0000000000003020 · Cited by 871
10. Cardiovascular Disease and Risk Management: Standards of Medical Care in Diabetes—2022
American Diabetes Association Professional Practice Committee (2022) · Diabetes Care · doi:10.2337/dc22-s010 · Cited by 869
Preeclampsia: Updates in Pathogenesis, Definitions, and Guidelines
Phipps, E., Prasanna, D., Brima, W., & Jim, B. (2016) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.12081115 · Cited by 651
Garovic, V. D., Dechend, R., Easterling, T., Karumanchi, S. A., McMurtry Baird, S., Magee, L. A., Rana, S., Vermunt, J. V., August, P., & on behalf of the American Heart Association Council on Hypertension; Council on the Kidney in Cardiovascular Disease, K. I. H. D. S. C. C. O. A. (2022) · Hypertension · doi:10.1161/hyp.0000000000000208 · Cited by 598
Self-citationMagee, L. A., Nicolaides, K. H., & von Dadelszen, P. (2022) · New England Journal of Medicine · doi:10.1056/nejmra2109523 · Cited by 613
Self-citationTreatment for mild chronic hypertension during pregnancy
Tita, A. T., Szychowski, J. M., Boggess, K., Dugoff, L., Sibai, B., Lawrence, K., Hughes, B. L., Bell, J., Aagaard, K., Edwards, R. K., et al. (2022) · New England Journal of Medicine · doi:10.1056/nejmoa2201295 · Cited by 567
15. Management of Diabetes in Pregnancy: Standards of Medical Care in Diabetes—2022
American Diabetes Association Professional Practice Committee (2022) · Diabetes Care · doi:10.2337/dc22-s015 · Cited by 504
10. Cardiovascular Disease and Risk Management: Standards of Medical Care in Diabetes—2021
American Diabetes Association (2021) · Diabetes Care · doi:10.2337/dc21-s010 · Cited by 495
10. Cardiovascular Disease and Risk Management: Standards of Medical Care in Diabetes—2020
American Diabetes Association (2020) · Diabetes Care · doi:10.2337/dc20-s010 · Cited by 487
10. Cardiovascular Disease and Risk Management: Standards of Care in Diabetes—2023
ElSayed, N. A., Aleppo, G., Aroda, V. R., Bannuru, R. R., Brown, F. M., Bruemmer, D., Collins, B. S., Das, S. R., Hilliard, M. E., Isaacs, D., et al. (2023) · Diabetes Care · doi:10.2337/dc23-s010 · Cited by 465
Active versus expectant management for women in the third stage of labour
Begley, C., Gyte, G. M., Devane, D., McGuire, W. L., & Weeks, A. D. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007412.pub4 · Cited by 448
10. Cardiovascular Disease and Risk Management: Standards of Care in Diabetes—2024
American Diabetes Association Professional Practice Committee, ElSayed, N. A., Aleppo, G., Bannuru, R. R., Bruemmer, D., Collins, B. S., Das, S. R., Ekhlaspour, L., Hilliard, M. E., Johnson, E. L., et al. (2024) · Diabetes Care · doi:10.2337/dc24-s010 · Cited by 438
14. Management of Diabetes in Pregnancy: Standards of Medical Care in Diabetes—2020
American Diabetes Association (2019) · Diabetes Care · doi:10.2337/dc20-s014 · Cited by 405
Jones, D. W., Ferdinand, K. C., Taler, S. J., Johnson, H. M., Shimbo, D., Abdalla, M., Altieri, M. M., Bansal, N., Bello, N. A., Bress, A. P., et al. (2025) · Hypertension · doi:10.1161/hyp.0000000000000249 · Cited by 424
2025 ESC Guidelines for the management of cardiovascular disease and pregnancy
Backer, J. F. A. D., Haugaa, K. H., Hasselberg, N. E., de Hosson, M., Brida, M., Castelletti, S., Cauldwell, M., Cerbai, E., Crotti, L., de Groot, N. M. S., et al. (2025) · European Heart Journal · doi:10.1093/eurheartj/ehaf193 · Cited by 380
Feig, D. S., Berger, H., Donovan, L., Godbout, A., Kader, T., Keely, E., & Sanghera, R. (2018) · Canadian Journal of Diabetes · doi:10.1016/j.jcjd.2017.10.038 · Cited by 344
10. Cardiovascular Disease and Risk Management: Standards of Care in Diabetes—2025
American Diabetes Association Professional Practice Committee, ElSayed, N. A., McCoy, R. G., Aleppo, G., Balapattabi, K., Beverly, E. A., Briggs Early, K., Bruemmer, D., Das, S. R., Echouffo-Tcheugui, J. B., et al. (2025) · Diabetes Care · doi:10.2337/dc25-s010 · Cited by 339
13. Management of Diabetes in Pregnancy: Standards of Medical Care in Diabetes—2018
American Diabetes Association (2018) · Diabetes Care · doi:10.2337/dc18-s013 · Cited by 332
Use of Medication for Cardiovascular Disease During Pregnancy
Halpern, D. G., Weinberg, C. R., Pinnelas, R., Mehta‐Lee, S. S., Economy, K. E., & Valente, A. M. (2019) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2018.10.075 · Cited by 322
15. Management of Diabetes in Pregnancy: Standards of Care in Diabetes—2023
ElSayed, N. A., Aleppo, G., Aroda, V. R., Bannuru, R. R., Brown, F. M., Bruemmer, D., Collins, B. S., Hilliard, M. E., Isaacs, D. M., Johnson, E. L., et al. (2022) · Diabetes Care · doi:10.2337/dc23-s015 · Cited by 345
Hypertension Across a Woman’s Life Cycle
WENGER, N. K., Arnold, A. M., Merz, C. N. B., Cooper‐DeHoff, R. M., Ferdinand, K. C., Fleg, J. L., Gulati, M., Isiadinso, I., Itchhaporia, D., Light-McGroary, K., et al. (2018) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2018.02.033 · Cited by 318
Magee, L. A., Smith, G. N., Bloch, C., Côté, A., Jain, V., Nerenberg, K. A., von Dadelszen, P., Helewa, M. E., & Rey, É. (2022) · Journal of Obstetrics and Gynaecology Canada · doi:10.1016/j.jogc.2022.03.002 · Cited by 309
Self-citationJones, D. W., Ferdinand, K. C., Taler, S. J., Johnson, H. M., Shimbo, D., Abdalla, M., Altieri, M. M., Bansal, N., Bello, N. A., Bress, A. P., et al. (2025) · Circulation · doi:10.1161/cir.0000000000001356 · Cited by 335
Clinical practice guideline on pregnancy and renal disease
Wiles, K., Chappell, L. C., Clark, K., Elman, L., Hall, M., Lightstone, L., Mohamed, G., Mukherjee, D., Nelson‐Piercy, C., Webster, P., et al. (2019) · BMC Nephrology · doi:10.1186/s12882-019-1560-2 · Cited by 305
Hypertension in pregnancy: Pathophysiology and treatment
Braunthal, S., & Brateanu, A. (2019) · SAGE Open Medicine · doi:10.1177/2050312119843700 · Cited by 312
Hypertensive disorders of pregnancy
Wu, P., Green, M., & Myers, J. (2023) · BMJ · doi:10.1136/bmj-2022-071653 · Cited by 293
Jones, D. W., Ferdinand, K. C., Taler, S. J., Johnson, H. M., Shimbo, D., Abdalla, M., Altieri, M. M., Bansal, N., Bello, N. A., Bress, A. P., et al. (2025) · JACC · doi:10.1016/j.jacc.2025.05.007 · Cited by 280
14. Management of Diabetes in Pregnancy: Standards of Medical Care in Diabetes—2021
American Diabetes Association (2020) · Diabetes Care · doi:10.2337/dc21-s014 · Cited by 291
14. Management of Diabetes in Pregnancy: Standards of Medical Care in Diabetes—2019
American Diabetes Association (2018) · Diabetes Care · doi:10.2337/dc19-s014 · Cited by 280
15. Management of Diabetes in Pregnancy: Standards of Care in Diabetes—2025
American Diabetes Association Professional Practice Committee, ElSayed, N. A., McCoy, R. G., Aleppo, G., Balapattabi, K., Beverly, E. A., Briggs Early, K., Bruemmer, D., Echouffo-Tcheugui, J. B., Ekhlaspour, L., et al. (2025) · Diabetes Care · doi:10.2337/dc25-s015 · Cited by 252
Hypertensive Disorders of Pregnancy and Future Maternal Cardiovascular Risk
Ying, W., Catov, J. M., & Ouyang, P. (2018) · Journal of the American Heart Association · doi:10.1161/jaha.118.009382 · Cited by 262
Hypertension Canada’s 2018 Guidelines for the Management of Hypertension in Pregnancy
Butalia, S., Audibert, F., Côté, A., Firoz, T., Logan, A. G., Magee, L. A., Mundle, W. R., Rey, É., Rabi, D. M., Daskalopoulou, S. S., et al. (2018) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2018.02.021 · Cited by 247
Self-citationThe CHIPS Randomized Controlled Trial (Control of Hypertension in Pregnancy Study)
Magee, L. A., von Dadelszen, P., Singer, J., Lee, T., Rey, É., Ross, S., Asztalos, E. V., Murphy, K. E., Menzies, J., Sanchez, J., et al. (2016) · Hypertension · doi:10.1161/hypertensionaha.116.07862 · Cited by 234
Self-citationPauli, J. M., & Repke, J. T. (2016) · Clinical Obstetrics & Gynecology · doi:10.1097/grf.0000000000000247 · Cited by 233
15. Management of Diabetes in Pregnancy: Standards of Care in Diabetes—2024
American Diabetes Association Professional Practice Committee, ElSayed, N. A., Aleppo, G., Bannuru, R. R., Bruemmer, D., Collins, B. S., Ekhlaspour, L., Hilliard, M. E., Johnson, E. L., Khunti, K., et al. (2024) · Diabetes Care · doi:10.2337/dc24-s015 · Cited by 232
All Hypertensive Disorders of Pregnancy Increase the Risk of Future Cardiovascular Disease
Tooher, J., Thornton, C. E., Makris, A., Ogle, R. F., Korda, A., & Hennessy, A. (2017) · Hypertension · doi:10.1161/hypertensionaha.117.09246 · Cited by 218
Sinkey, R. G., Battarbee, A. N., Bello, N. A., Ives, C. W., Oparil, S., & Tita, A. (2020) · Current Hypertension Reports · doi:10.1007/s11906-020-01082-w · Cited by 208
Hypertensive Disorders of Pregnancy
Khedagi, A. M., & Bello, N. A. (2020) · Cardiology Clinics · doi:10.1016/j.ccl.2020.09.005 · Cited by 225
Preventing deaths due to the hypertensive disorders of pregnancy
von Dadelszen, P., & Magee, L. A. (2016) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1016/j.bpobgyn.2016.05.005 · Cited by 195
Self-citationRamos, J. G. L., Sass, N., & Costa, S. H. M. (2017) · Revista Brasileira Ginecologia e Obstetrícia · doi:10.1055/s-0037-1604471 · Cited by 186
13. Management of Diabetes in Pregnancy
American Diabetes Association (2016) · Diabetes Care · doi:10.2337/dc17-s016 · Cited by 184
Management of Preexisting Diabetes in Pregnancy
Alexopoulos, A., Blair, R. A., & Peters, A. L. (2019) · JAMA · doi:10.1001/jama.2019.4981 · Cited by 183
RSSDI-ESI clinical practice recommendations for the management of type 2 diabetes mellitus 2020
Madhu, S., Chawla, R., Makkar, B. M., Ghosh, S. K., Saboo, B., & Kalra, S. (2020) · Indian Journal of Endocrinology and Metabolism · doi:10.4103/ijem.ijem_225_20 · Cited by 182
Scott, G. M., Gillon, T. E. R., Pels, A., von Dadelszen, P., & Magee, L. A. (2020) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2020.08.018 · Cited by 177
Self-citationThe Impact of Kidney Development on the Life Course: A Consensus Document for Action
The Low Birth Weight and Nephron Number Working Group (2017) · The Nephron journals/Nephron journals · doi:10.1159/000457967 · Cited by 172
Hypertensive Disorders of Pregnancy
Wilkerson, R. G., & Ogunbodede, A. C. (2019) · Emergency Medicine Clinics of North America · doi:10.1016/j.emc.2019.01.008 · Cited by 174
Chinese Guidelines for the Prevention and Treatment of Hypertension (2024 revision)
Wang, J. (2025) · 老年心脏病学杂志：英文版 · doi:10.26599/1671-5411.2025.01.008 · Cited by 170
Shahul, S. S., Tung, A., Minhaj, M. M., Nizamuddin, J., Wenger, J., Mahmood, E., Mueller, A., Shaefi, S., Scavone, B. M., Kociol, R. D., et al. (2015) · Hypertension in Pregnancy · doi:10.3109/10641955.2015.1090581 · Cited by 165
Agrawal, A., & WENGER, N. K. (2020) · Current Hypertension Reports · doi:10.1007/s11906-020-01070-0 · Cited by 168
Cabiddu, G., Castellino, S., Gernone, G., Santoro, D., Moroni, G. L., Giannattasio, M., Gregorini, G. A., Giacchino, F., Attini, R., Loi, V., et al. (2016) · Journal of Nephrology · doi:10.1007/s40620-016-0285-6 · Cited by 153
Hypertensive Disorders in Pregnancy
Sutton, A. L. M., Harper, L. M., & Tita, A. (2018) · Obstetrics and Gynecology Clinics of North America · doi:10.1016/j.ogc.2018.01.012 · Cited by 152
Circulating Angiogenic Factor Levels in Hypertensive Disorders of Pregnancy
Thadhani, R., Lemoine, E. R., Rana, S., Costantine, M. M., Calsavara, V. F., Boggess, K., Wylie, B. J., Simas, T. A. M., Louis, J. M., Espinoza, J., et al. (2022) · NEJM Evidence · doi:10.1056/evidoa2200161 · Cited by 149
Pregnancy in chronic kidney disease and kidney transplantation
Webster, P., Lightstone, L., McKay, D. B., & Josephson, M. A. (2017) · Kidney International · doi:10.1016/j.kint.2016.10.045 · Cited by 149
Hypertension in Pregnancy: A Diagnostic and Therapeutic Overview
Cífková, R. (2023) · High Blood Pressure & Cardiovascular Prevention · doi:10.1007/s40292-023-00582-5 · Cited by 158
Capítulo 1 - Conceituação, Epidemiologia e Prevenção Primária
Malachias, M. V. B., Souza, W., Plavnik, F. L., Rodrigues, C., Brandão, A., Neves, M. F., Bortolotto, L. A., Franco, R., Figueiredo, C., Jardim, P., et al. (2016) · Arquivos Brasileiros de Cardiologia · doi:10.5935/abc.20160151 · Cited by 152
Magee, L. A., Sharma, S., Nathan, H. L., Adetoro, O. O., Bellad, M. B., Goudar, S. S., Macuácua, S., Mallapur, A. A., Qureshi, R. N., Sevene, E., et al. (2019) · PLoS Medicine · doi:10.1371/journal.pmed.1002783 · Cited by 139
Self-citationChronic hypertension in pregnancy
Battarbee, A. N., Sinkey, R. G., Harper, L. M., Oparil, S., & Tita, A. (2019) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2019.11.1243 · Cited by 149
Metoki, H., Iwama, N., Hamada, H., Satoh, M., Murakami, T., Ishikuro, M., & Obara, T. (2022) · Hypertension Research · doi:10.1038/s41440-022-00965-6 · Cited by 142
Hypertension in Pregnancy and Postpartum: Current Standards and Opportunities to Improve Care
Countouris, M. E., Mahmoud, Z., Cohen, J. B., Crousillat, D. R., Hameed, A. B., Harrington, C. M., Hauspurg, A. K., Honigberg, M. C., Lewey, J., Lindley, K. J., et al. (2025) · Circulation · doi:10.1161/circulationaha.124.073302 · Cited by 146
Maternal Outcomes Associated With Lower Range Stage 1 Hypertension
Sutton, E. F., Hauspurg, A. K., Caritis, S. N., Powers, R. W., & Catov, J. M. (2018) · Obstetrics and Gynecology · doi:10.1097/aog.0000000000002870 · Cited by 129
Reproductive health and pregnancy in women with chronic kidney disease
Wiles, K., Nelson‐Piercy, C., & Bramham, K. (2018) · Nature Reviews Nephrology · doi:10.1038/nrneph.2017.187 · Cited by 128
Accuracy of Blood Pressure Measurement Devices in Pregnancy
Bello, N. A., Woolley, J. J., Cleary, K. L., Falzon, L., Alpert, B. S., Oparil, S., Cutter, G., Wapner, R. J., Muntner, P., Tita, A., et al. (2017) · Hypertension · doi:10.1161/hypertensionaha.117.10295 · Cited by 126
Late Pregnancy β Blocker Exposure and Risks of Neonatal Hypoglycemia and Bradycardia
Bateman, B. T., Patorno, E., Desai, R. J., Seely, E. W., Mogun, H., Maeda, A., Fischer, M. A., Hernández–Dı́az, S., & Huybrechts, K. F. (2016) · PEDIATRICS · doi:10.1542/peds.2016-0731 · Cited by 125
Poon, L. C., Magee, L. A., Verlohren, S., Shennan, A. H., von Dadelszen, P., Sheiner, E., Hadar, E., Visser, G. H. A., Costa, F. D. S., Kapur, A., et al. (2021) · International Journal of Gynecology & Obstetrics · doi:10.1002/ijgo.13763 · Cited by 123
Self-citationRecent advances in the diagnosis and management of pre-eclampsia
Duhig, K. E., Vandermolen, B. I., & Shennan, A. H. (2018) · F1000Research · doi:10.12688/f1000research.12249.1 · Cited by 113
Pregnancy and Glomerular Disease
Blom, K. C., Odutayo, A., Bramham, K., & Hladunewich, M. (2017) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.00130117 · Cited by 110
Contribution of hypertension to severe maternal morbidity
Hitti, J. E., Sienas, L., Walker, S., Benedetti, T. J., & Easterling, T. R. (2018) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2018.07.002 · Cited by 109
Tucker, K. L., Mort, S., Yu, L., Campbell, H., Rivero‐Arias, O., Wilson, H. M., Allen, J., Band, R. J., Chisholm, A., Crawford, C., et al. (2022) · JAMA · doi:10.1001/jama.2022.4712 · Cited by 116
12. Management of Diabetes in Pregnancy
American Diabetes Association (2015) · Diabetes Care · doi:10.2337/dc16-s015 · Cited by 111
Bellos, I., Pergialiotis, V., Papapanagiotou, A., Loutradis, D., & Daskalakis, G. (2020) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2020.03.016 · Cited by 103
Recent advances in the diagnosis and management of pre-eclampsia
Duhig, K. E., & Shennan, A. H. (2015) · F1000Prime Reports · doi:10.12703/p7-24 · Cited by 101
The management of hypertension in women planning for pregnancy
Lu, Y., Chen, R., Cai, J., Huang, Z., & Yuan, H. (2018) · British Medical Bulletin · doi:10.1093/bmb/ldy035 · Cited by 106
Stroke in Pregnancy: A Focused Update
Miller, E. C., & Leffert, L. R. (2019) · Anesthesia & Analgesia · doi:10.1213/ane.0000000000004203 · Cited by 96
Webster, L., Conti-Ramsden, F. I., Seed, P. T., Webb, A. J., Nelson‐Piercy, C., & Chappell, L. C. (2017) · Journal of the American Heart Association · doi:10.1161/jaha.117.005526 · Cited by 96
Ahmad, A., & Oparil, S. (2017) · Hypertension · doi:10.1161/hypertensionaha.117.08317 · Cited by 94
Management of hypertensive crisis: British and Irish Hypertension Society Position document
Kulkarni, S., Glover, M., Kapil, V., Abrams, S. M. L., Partridge, S., McCormack, T., Sever, P. S., Delles, C., & Wilkinson, I. B. (2022) · Journal of Human Hypertension · doi:10.1038/s41371-022-00776-9 · Cited by 89
Chronic Kidney Disease and Pregnancy
Hui, D., & Hladunewich, M. (2019) · Obstetrics and Gynecology · doi:10.1097/aog.0000000000003256 · Cited by 87
Labetalol Versus Nifedipine as Antihypertensive Treatment for Chronic Hypertension in Pregnancy
Webster, L., Myers, J., Nelson‐Piercy, C., Harding, K., Cruickshank, J. K., Watt‐Coote, I., Khalil, A. A., Wiesender, C., Seed, P. T., & Chappell, L. C. (2017) · Hypertension · doi:10.1161/hypertensionaha.117.09972 · Cited by 87
Magee, L. A., the CHIPS Study Group, von Dadelszen, P., Singer, J., Lee, T., Rey, É., Ross, S., Asztalos, E. V., Murphy, K. E., Menzies, J., et al. (2015) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/1471-0528.13569 · Cited by 84
Self-citationBone, J. N., Sandhu, A., Abalos, E. J., Khalil, A. A., Singer, J., Prasad, S., Omar, S., Vidler, M., von Dadelszen, P., & Magee, L. A. (2022) · Hypertension · doi:10.1161/hypertensionaha.121.18415 · Cited by 86
Self-citationOhya, Y., Arakawa, K., Arata, N., Arima, S., Arima, H., Asayama, K., Dohi, Y., Fukami, A., Furuhashi, M., Goto, K., et al. (2026) · Hypertension Research · doi:10.1038/s41440-025-02462-y · Cited by 91
Cabiddu, G., Spotti, D., Gernone, G., Santoro, D., Moroni, G. L., Gregorini, G. A., Giacchino, F., Attini, R., Limardo, M., Gammaro, L., et al. (2018) · Journal of Nephrology · doi:10.1007/s40620-018-0499-x · Cited by 82
Khalaf, S. Y. A., O’Reilly, É. J., Barrett, P., Leite, D. F. B., Pawley, L. C., McCarthy, F. P., & Khashan, A. S. (2021) · Journal of the American Heart Association · doi:10.1161/jaha.120.018494 · Cited by 82
Metadata
- Authors
- Magee, L. A., von Dadelszen, P., Rey, E., Ross, S., Asztalos, E., Murphy, K. E., Menzies, J., Sanchez, J., Singer, J., Gafni, A., Gruslin, A., Helewa, M., Hutton, E., Lee, S. K., Lee, T., Logan, A. G., Ganzevoort, W., Welch, R., Thornton, J. G., & Moutquin, J.-M.
- Affiliations
- University of British Columbia (CA)
- University of Alberta (CA)
- University of Toronto (CA)
- McMaster University (CA)
- University of Ottawa (CA)
- University of Manitoba (CA)
- University of Amsterdam (NL)
- Derriford Hospital (GB)
- University of Nottingham (GB)
- Université de Sherbrooke (CA)
- ORCID
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2015-01-29
- Volume
- 372
- Issue
- 5
- Pages
- 407-417
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2135528524
- Cited by
- 672
- References
- 23
- Citations by year
- 2026: 37 · 2025: 52 · 2024: 47 · 2023: 67 · 2022: 76 · 2021: 56 · 2020: 56 · 2019: 65 · 2018: 74 · 2017: 57 · 2016: 52 · 2015: 31
- FWCI
- 81.17
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Repository@Nottingham (University of Nottingham) (publishedVersion, other-oa)
- St George's Online Research Archive (St George's University of London) (acceptedVersion)
- Repository@Nottingham (University of Nottingham) (submittedVersion, cc-by)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Nottingham ePrints (University of Nottingham) (submittedVersion)
- Research Portal (King's College London) (submittedVersion)
- Pure Amsterdam UMC (submittedVersion, other-oa)
- Funders
- Canadian Institutes of Health Research (87522_1)
- Topics
- Health Sciences › Medicine › Obstetrics and Gynecology › Pregnancy and preeclampsia studies
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Health Sciences › Medicine › Obstetrics and Gynecology › Gestational Diabetes Research and Management
- Keywords
- hypertension in pregnancy, blood pressure control, tight blood pressure control, gestational hypertension, pre-existing hypertension, miscarriage, neonatal intensive care, maternal complications, severe hypertension in pregnancy, antihypertensive therapy, postpartum complications, preeclampsia, eclampsia
- MeSH terms
- Abortion, Spontaneous, Adult, Antihypertensive Agents, Blood Pressure, Female, Humans, Infant, Newborn, Pregnancy, Pregnancy Complications, Pregnancy Outcome, Puerperal Disorders, Intensive Care, Neonatal, Hypertension, Pregnancy-Induced, Perinatal Death
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
