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Approaches to Catheter Ablation for Persistent Atrial Fibrillation
Open accessAbstract
BACKGROUND: Catheter ablation is less successful for persistent atrial fibrillation than for paroxysmal atrial fibrillation. Guidelines suggest that adjuvant substrate modification in addition to pulmonary-vein isolation is required in persistent atrial fibrillation. METHODS: We randomly assigned 589 patients with persistent atrial fibrillation in a 1:4:4 ratio to ablation with pulmonary-vein isolation alone (67 patients), pulmonary-vein isolation plus ablation of electrograms showing complex fractionated activity (263 patients), or pulmonary-vein isolation plus additional linear ablation across the left atrial roof and mitral valve isthmus (259 patients). The duration of follow-up was 18 months. The primary end point was freedom from any documented recurrence of atrial fibrillation lasting longer than 30 seconds after a single ablation procedure. RESULTS: Procedure time was significantly shorter for pulmonary-vein isolation alone than for the other two procedures (P<0.001). After 18 months, 59% of patients assigned to pulmonary-vein isolation alone were free from recurrent atrial fibrillation, as compared with 49% of patients assigned to pulmonary-vein isolation plus complex electrogram ablation and 46% of patients assigned to pulmonary-vein isolation plus linear ablation (P=0.15). There were also no significant differences among the three groups for the secondary end points, including freedom from atrial fibrillation after two ablation procedures and freedom from any atrial arrhythmia. Complications included tamponade (three patients), stroke or transient ischemic attack (three patients), and atrioesophageal fistula (one patient). CONCLUSIONS: Among patients with persistent atrial fibrillation, we found no reduction in the rate of recurrent atrial fibrillation when either linear ablation or ablation of complex fractionated electrograms was performed in addition to pulmonary-vein isolation. (Funded by St. Jude Medical; ClinicalTrials.gov number, NCT01203748.).
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“PVI was initially tested in patients with paroxysmal AF, but appears to be non-inferior to more extensive ablation in persistent AF as well.729,735”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [735]
In the citing paper
“Sinus rhythm without severely symptomatic recurrences of AF is found in up to 70% of patients with paroxysmal AF, and around 50% in persistent AF. 713,728,735,1042”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [735]
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“Although a plethora of different additional ablation techniques have been published, their added value is questionable in patients undergoing a first catheter ablation, including those with persistent AF. 735”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [735]
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Gage, B. F., Waterman, A. D., Shannon, W., Boechler, M., Rich, M. W., & Radford, M. J. (2001) · JAMA · doi:10.1001/jama.285.22.2864 · Cited by 4,832
January, C. T., Wann, L. S., Alpert, J. S., Calkins, H., Cigarroa, J. E., Cleveland, J. C., Conti, J. B., Ellinor, P. T., Ezekowitz, M. D., Field, M. E., et al. (2014) · Circulation · doi:10.1161/cir.0000000000000040 · Cited by 2,056
Nademanee, K., McKenzie, J. P., Kosar, E. M., Schwab, M., Sunsaneewitayakul, B., Vasavakul, T., Khunnawat, C., & Ngarmukos, T. (2004) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2003.12.054 · Cited by 2,004
Calkins, H. G., Brugada, J., Packer, D. L., Cappato, R., Chen, S., Crijns, H. J. G. M., Damiano, R. J., Davies, D. W., Haines, D. E., Haı̈ssaguerre, M., et al. (2007) · Heart Rhythm · doi:10.1016/j.hrthm.2007.04.005 · Cited by 1,690
Calkins, H. G., Kück, K., Cappato, R., Brugada, J., Camm, A. J., Chen, S., Crijns, H. J. G. M., Damiano, R. J., Davies, D. W., Dimarco, J., et al. (2012) · Journal of Interventional Cardiac Electrophysiology · doi:10.1007/s10840-012-9672-7 · Cited by 1,685
Calkins, H., Kuck, K. H., Cappato, R., Brugada, J., Camm, A. J., Chen, S.-A., Crijns, H. J. G., Damiano, R. J., Davies, D. W., DiMarco, J., et al. (2012) · Heart Rhythm · doi:10.1016/j.hrthm.2011.12.016 · Cited by 1,456
Wilber, D. J., Pappone, C., Neuzil, P., De Paola, A., Marchlinski, F., Natale, A., Macle, L., Daoud, E. G., Calkins, H., Hall, B., et al. (2010) · JAMA · doi:10.1001/jama.2009.2029 · Cited by 1,170
Self-citationCircumferential Pulmonary-Vein Ablation for Chronic Atrial Fibrillation
Oral, H., Pappone, C., Chugh, A., Good, E. D., Bogun, F. M., Pelosi, F., Bates, E., Lehmann, M. H., Vicedomini, G., Augello, G., et al. (2006) · New England Journal of Medicine · doi:10.1056/nejmoa050955 · Cited by 975
Calkins, H., Reynolds, M. R., Spector, P., Sondhi, M., Xu, Y., Martin, A., Williams, C. J., & Sledge, I. (2009) · Circulation Arrhythmia and Electrophysiology · doi:10.1161/circep.108.824789 · Cited by 847
Technique and Results of Linear Ablation at the Mitral Isthmus
Jaı̈s, P., Hocini, M., Hsu, L., Sanders, P., Scavée, C., Weerasooriya, R., Macle, L., Raybaud, F., Garrigue, S., Shah, D. C., et al. (2004) · Circulation · doi:10.1161/01.cir.0000146917.75041.58 · Cited by 751
Self-citationDeshmukh, A. J., Patel, N., Pant, S., Shah, N. N., Chothani, A., Mehta, K. D., Grover, P. M., Singh, V., Vallurupalli, S., Savani, G. T., et al. (2013) · Circulation · doi:10.1161/circulationaha.113.003862 · Cited by 580
Stabile, G., Bertaglia, E., Senatore, G., Simone, A. D., Zoppo, F., Donnici, G., Turco, P., Pascotto, P., FAZZARI, M., & Vitale, D. F. (2005) · European Heart Journal · doi:10.1093/eurheartj/ehi583 · Cited by 502
Outcomes of long-standing persistent atrial fibrillation ablation: A systematic review
Brooks, A. G., Stiles, M. K., Laborderie, J., Lau, D. H., Kuklik, P., SHIPP, N. J., Hsu, L., & Sanders, P. (2010) · Heart Rhythm · doi:10.1016/j.hrthm.2010.01.017 · Cited by 488
Self-citationMont, L., Bisbal, F., Hernández-Madrid, A., Pérez-Castellano, N., Viñolas, X., Arenal, A., Arribas, F., Fernández-Lozano, I., Bodegas, A., Cobos, A., et al. (2014) · European Heart Journal · doi:10.1093/eurheartj/eht457 · Cited by 394
Narayan, S. M., Baykaner, T., Clopton, P., Schricker, A. A., Lalani, G., Krummen, D. E., Shivkumar, K., & Miller, J. M. (2014) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2014.02.543 · Cited by 367
Willems, S., Klemm, H. U., Rostock, T., Brandstrup, B., Ventura, R., Steven, D., Risius, T., Lutomsky, B. A., & Meinertz, T. (2006) · European Heart Journal · doi:10.1093/eurheartj/ehl093 · Cited by 334
Oral, H., Chugh, A., Yoshida, K., SARRAZIN, J., Kühne, M., Crawford, T. C., Chalfoun, N. T., Wells, D., Boonyapisit, W., Veerareddy, S., et al. (2009) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.10.054 · Cited by 330
Elayi, C. S., Verma, A., Biase, L. D., Ching, C. K., Patel, D., Barrett, C. D., Martin, D. O., Bai, R., Fahmy, T. S. E., Khaykin, Y., et al. (2008) · Heart Rhythm · doi:10.1016/j.hrthm.2008.09.016 · Cited by 321
Self-citationVerma, A., Mantovan, R., Macle, L., Martino, G. D., Chen, J., Morillo, C. A., NOVAK, P. G., Calzolari, V., Guerra, P. G., Nair, G. M., et al. (2010) · European Heart Journal · doi:10.1093/eurheartj/ehq041 · Cited by 315
Self-citationRandomized Ablation Strategies for the Treatment of Persistent Atrial Fibrillation
Dixit, S., Marchlinski, F. E., Lin, D., Callans, D. J., Bala, R., Riley, M. P., Garcia, F. C., Hutchinson, M. D., Ratcliffe, S. J., Cooper, J. M., et al. (2011) · Circulation Arrhythmia and Electrophysiology · doi:10.1161/circep.111.966226 · Cited by 281
Left atrial linear lesions are required for successful treatment of persistent atrial fibrillation
Knecht, S., Hocini, M., Wright, M. J., Lellouche, N., O'Neill, M. D., Matsuo, S., Nault, I., Chauhan, V. S., Makati, K. J., Bevilacqua, M., et al. (2008) · European Heart Journal · doi:10.1093/eurheartj/ehn302 · Cited by 259
Sawhney, N. S., Anousheh, R., Chen, W., & Feld, G. K. (2010) · Circulation Arrhythmia and Electrophysiology · doi:10.1161/circep.109.924878 · Cited by 248
Fassini, G. M., Riva, S. I., Chiodelli, R., Trevisi, N. M., Berti, M., Carbucicchio, C., Maccabelli, G., Giraldi, F., & Bella, P. E. D. (2005) · Journal of Cardiovascular Electrophysiology · doi:10.1111/j.1540-8167.2005.50192.x · Cited by 244
Arbelo, E., Brugada, J., Hindricks, G., Maggioni, A. P., Tavazzi, L., Vardas, P., Laroche, C., Anselme, F., Inama, G., Jais, P., et al. (2014) · European Heart Journal · doi:10.1093/eurheartj/ehu001 · Cited by 212
Verma, A., NOVAK, P. G., Macle, L., Whaley, B., Beardsall, M., Wulffhart, Z. A., & Khaykin, Y. (2007) · Heart Rhythm · doi:10.1016/j.hrthm.2007.09.027 · Cited by 185
Self-citationValidation of a New Simple Scale to Measure Symptoms in Atrial Fibrillation
Dorian, P., Guerra, P. G., Kerr, C. R., O’Donnell, S., Crystal, E., Gillis, A. M., Mitchell, L. B., Roy, D., Skanes, A. C., Rose, M. S., et al. (2009) · Circulation Arrhythmia and Electrophysiology · doi:10.1161/circep.108.812347 · Cited by 180
Verma, A., Macle, L., Cox, J. L., & Skanes, A. C. (2011) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2010.11.011 · Cited by 99
Self-citationVerma, A., Sanders, P., Macle, L., Deisenhofer, I., Morillo, C. A., Chen, J., Jiang, C.-Y., Ernst, S., & Mantovan, R. (2012) · American Heart Journal · doi:10.1016/j.ahj.2012.04.002 · Cited by 57
Self-citationPrevalence and Types of Pitfall in the Assessment of Mitral Isthmus Linear Conduction Block
Shah, A. J., Pascale, P., Miyazaki, S., Liu, X., Roten, L., Derval, N., Jadidi, A., Scherr, D., Wilton, S. B., Pedersen, M. E. F., et al. (2012) · Circulation Arrhythmia and Electrophysiology · doi:10.1161/circep.112.971259 · Cited by 57
Persistent atrial fibrillation: current approach and controversies
Parkash, R., Verma, A., & Tang, A. (2009) · Current Opinion in Cardiology · doi:10.1097/hco.0b013e3283336d52 · Cited by 45
Self-citationVerma, A. (2010) · Current Opinion in Cardiology · doi:10.1097/hco.0b013e3283413925 · Cited by 43
Self-citationShah, A. J., Jadidi, A., Liu, X., Miyazaki, S., Forclaz, A., Nault, I., Rivard, L., Linton, N., Xhaët, O., Derval, N., et al. (2010) · Cardiology Research and Practice · doi:10.4061/2010/950763 · Cited by 43
A Critical Perspective on the Role of Catheter Ablation in Management of Atrial Fibrillation
Wyse, D. G. (2013) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2013.03.001 · Cited by 10
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2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS
Kirchhof, P. F., Benussi, S., Kotecha, D., Ahlsson, A., Atar, D., Casadei, B., Castellà, M., Diener, H., Heidbüchel, H., Hendriks, J., et al. (2016) · EP Europace · doi:10.1093/europace/euw295 · Cited by 6,438
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Arbelo, E., Protonotarios, A., Gimeno, J. R., Arbustini, E., Barriales-Villa, R., Basso, C., Bezzina, C. R., Biagini, E., Blom, N. A., de Boer, R. A., et al. (2023) · European Heart Journal · doi:10.1093/eurheartj/ehad194 · Cited by 2,844
Calkins, H. G., Hindricks, G., Cappato, R., Kim, Y., Saad, E., Aguinaga, L., Akar, J. G., Badhwar, V., Brugada, J., Camm, A. J., et al. (2017) · Heart Rhythm · doi:10.1016/j.hrthm.2017.05.012 · Cited by 2,794
Self-citation
Metadata
- Authors
- Verma, A., Jiang, C.-Y., Betts, T. R., Chen, J., Deisenhofer, I., Mantovan, R., Macle, L., Morillo, C. A., Haverkamp, W., Weerasooriya, R., Albenque, J.-P., Nardi, S., Menardi, E., Novak, P., & Sanders, P.
- Affiliations
- Montreal Heart Institute (CA)
- John Radcliffe Hospital (GB)
- Haukeland University Hospital (NO)
- Deutsches Herzzentrum München (DE)
- Ospedale “M. Bufalini” di Cesena (IT)
- McMaster University (CA)
- Charité – Universitätsmedizin Berlin (DE)
- Hollywood Private Hospital (AU)
- Clinique Pasteur (FR)
- Azienda Sanitaria Ospedaliera S.Croce e Carle Cuneo (IT)
- Royal Jubilee Hospital (CA)
- Royal Adelaide Hospital (AU)
- ORCID
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2015-05-07
- Volume
- 372
- Issue
- 19
- Pages
- 1812-1822
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W1583406651
- Cited by
- 2,339
- References
- 33
- Citations by year
- 2026: 162 · 2025: 191 · 2024: 213 · 2023: 176 · 2022: 253 · 2021: 186 · 2020: 231 · 2019: 222 · 2018: 205 · 2017: 227 · 2016: 193 · 2015: 71
- FWCI
- 168.71
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- UWA Profiles and Research Repository (UWA) (submittedVersion)
- Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
- Keywords
- persistent atrial fibrillation, catheter ablation, pulmonary vein isolation, complex fractionated atrial electrograms, linear ablation, left atrial roof, atrial fibrillation recurrence
- MeSH terms
- Aged, Atrial Fibrillation, Electrocardiography, Female, Heart Atria, Humans, Male, Middle Aged, Mitral Valve, Pulmonary Veins, Recurrence, Stroke Volume, Proportional Hazards Models, Catheter Ablation, Disease-Free Survival, Kaplan-Meier Estimate, Secondary Prevention, Operative Time
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