Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development

Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells

Boyer, L. A., Lee, T. I., Cole, M. F., Johnstone, S. E., Levine, S. S., Zucker, J. P., Guenther, M. G., Kumar, R. M., Murray, H. L., Jenner, R. G., et al. (2005) · Cell · doi:10.1016/j.cell.2005.08.020 · Cited by 4,505 · see citing works

An Introduction to Systems Biology: Design Principles of Biological Circuits

Alon, U. (2006) · doi:10.1201/9781420011432 · Cited by 2,825 · see citing works

AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis.

Okuda, T., van Deursen, J., Hiebert, S. W., Grosveld, G., & Downing, J. R. (1996) · Cell · doi:10.1016/s0092-8674(00)80986-1 · Cited by 1,856 · see citing works

Stem Cells

Weissman, I. L. (2000) · Cell · doi:10.1016/s0092-8674(00)81692-x · Cited by 1,827 · see citing works

An early haematopoietic defect in mice lacking the transcription factor GATA-2

Tsai, F., Keller, G. M., Kuo, F. C., Weiss, M. J., Chen, J., Rosenblatt, M., Alt, F. W., & Orkin, S. H. (1994) · Nature · doi:10.1038/371221a0 · Cited by 1,419 · see citing works

A common precursor for hematopoietic and endothelial cells

Choi, K., Kennedy, M., Kazarov, A. R., Papadimitriou, J. C., & Keller, G. M. (1998) · Development · doi:10.1242/dev.125.4.725 · Cited by 1,410 · see citing works

Transcription regulation and animal diversity

Levine, M., & Tjian, R. (2003) · Nature · doi:10.1038/nature01763 · Cited by 1,309 · see citing works

Gene Regulatory Networks and the Evolution of Animal Body Plans

Davidson, E. H., & Erwin, D. H. (2006) · Science · doi:10.1126/science.1113832 · Cited by 1,207 · see citing works

Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis.

Wang, Q., Stacy, T., Binder, M., Marin-Padilla, M., Sharpe, A. H., & Speck, N. A. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.8.3444 · Cited by 1,178 · see citing works

An Introduction to Systems Biology: Design Principles of Biological Circuits

Alon, U. (2019) · doi:10.1201/9780429283321 · Cited by 955 · see citing works

sonic hedgehog and vascular endothelial growth factor Act Upstream of the Notch Pathway during Arterial Endothelial Differentiation

Lawson, N. D., Vogel, A. M., & Weinstein, B. M. (2002) · Developmental Cell · doi:10.1016/s1534-5807(02)00198-3 · Cited by 813 · see citing works

Gene regulatory networks for development

Levine, M., & Davidson, E. H. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0408031102 · Cited by 796 · see citing works

The T Cell Leukemia Oncoprotein SCL/tal-1 Is Essential for Development of All Hematopoietic Lineages

Porcher, C., Swat, W., Rockwell, K. R., Fujiwara, Y., Alt, F. W., & Orkin, S. H. (1996) · Cell · doi:10.1016/s0092-8674(00)80076-8 · Cited by 731 · see citing works

The timing of eukaryotic evolution: Does a relaxed molecular clock reconcile proteins and fossils?

Douzery, E. J. P., Snell, E. A., Bapteste, E., Delsuc, F., & Philippe, H. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0403984101 · Cited by 638 · see citing works

Intraaortic hemopoietic cells are derived from endothelial cells during ontogeny

Jaffredo, T., Gautier, R., Eichmann, A., & Dieterlen‐Lièvre, F. (1998) · Development · doi:10.1242/dev.125.22.4575 · Cited by 580 · see citing works

Tracking mesoderm induction and its specification to the hemangioblast during embryonic stem cell differentiation

Fehling, H. J., Lacaud, G., Kubo, A., Kennedy, M., Robertson, S. M., Keller, G. M., & Kouskoff, V. (2003) · Development · doi:10.1242/dev.00589 · Cited by 500 · see citing works

Notch1 but Not Notch2 Is Essential for Generating Hematopoietic Stem Cells from Endothelial Cells

Kumano, K., Chiba, S., Kunisato, A., Sata, M., Saito, T., Nakagami‐Yamaguchi, E., Yamaguchi, T., Masuda, S., Shimizu, K., Takahashi, T., et al. (2003) · Immunity · doi:10.1016/s1074-7613(03)00117-1 · Cited by 466 · see citing works

The Murine Placenta Contains Hematopoietic Stem Cells within the Vascular Labyrinth Region

Ottersbach, K., & Dzierzak, E. A. (2005) · Developmental Cell · doi:10.1016/j.devcel.2005.02.001 · Cited by 446 · see citing works

The SCL gene specifies haemangioblast development from early mesoderm

Gering, M., Rodaway, A., Göttgens, B., Patient, R. K., & Green, A. R. (1998) · The EMBO Journal · doi:10.1093/emboj/17.14.4029 · Cited by 414 · see citing works

A directed screen for genes involved in Drosophila blood cell activation

Zettervall, C.-J., Ines, A., Williams, M. J., Palmer, R. H., Kurucz, É., Andó, I., & Hultmark, D. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0403789101 · Cited by 366 · see citing works

GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodeling

Grass, J. A., Boyer, M. E., Pal, S. K., Wu, J., Weiss, M. J., & Bresnick, E. H. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1432147100 · Cited by 357 · see citing works

The scl gene product is required for the generation of all hematopoietic lineages in the adult mouse.

Robb, L. G., Elwood, N. J., Elefanty, A. G., Köntgen, F., Li, R., Barnett, L. D., & Begley, C. G. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb00787.x · Cited by 338 · see citing works

Hedgehog Signaling Is Required for Adult Blood Stem Cell Formation in Zebrafish Embryos

Gering, M., & Patient, R. K. (2005) · Developmental Cell · doi:10.1016/j.devcel.2005.01.010 · Cited by 328 · see citing works

Control of Cardiac Development by an Evolutionarily Conserved Transcriptional Network

Cripps, R. M., & Olson, E. N. (2002) · Developmental Biology · doi:10.1006/dbio.2002.0666 · Cited by 319 · see citing works

RBPjκ-dependent Notch function regulatesGata2and is essential for the formation of intra-embryonic hematopoietic cells

Robert‐Moreno, A., Espinosa, L., de la Pompa, J. L., & Bigas, A. (2005) · Development · doi:10.1242/dev.01660 · Cited by 278 · see citing works

Developmental gene regulatory network architecture across 500 million years of echinoderm evolution

Hinman, V. F., Nguyen, A. T., Cameron, R. A., & Davidson, E. H. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2235868100 · Cited by 272 · see citing works

SLAM family markers are conserved among hematopoietic stem cells from old and reconstituted mice and markedly increase their purity

Yilmaz, Ö. H., Kiel, M. J., & Morrison, S. J. (2005) · Blood · doi:10.1182/blood-2005-05-2140 · Cited by 266 · see citing works

Distinct Origins of Adult and Embryonic Blood in Xenopus

Ciau‐Uitz, A., Walmsley, M. E., & Patient, R. K. (2000) · Cell · doi:10.1016/s0092-8674(00)00067-2 · Cited by 227 · see citing works

Evidence for a fruit fly hemangioblast and similarities between lymph-gland hematopoiesis in fruit fly and mammal aorta-gonadal-mesonephros mesoderm

Mandal, L., Banerjee, U. K., & Hartenstein, V. (2004) · Nature Genetics · doi:10.1038/ng1404 · Cited by 214 · see citing works

Establishing the transcriptional programme for blood: the SCL stem cell enhancer is regulated by a multiprotein complex containing Ets and GATA factors

Göttgens, B., Nastos, A., Kinston, S., Piltz, S., Delabesse, E. C. M., Stanley, M., Sanchez, M., Ciau‐Uitz, A., Patient, R., & Green, A. R. (2002) · The EMBO Journal · doi:10.1093/emboj/cdf286 · Cited by 212 · see citing works

Loops, Lineage, and Leukemia

Enver, T., & Greaves, M. F. (1998) · Cell · doi:10.1016/s0092-8674(00)81215-5 · Cited by 185 · see citing works

TAL1 and LIM-Only Proteins Synergistically Induce Retinaldehyde Dehydrogenase 2 Expression in T-Cell Acute Lymphoblastic Leukemia by Acting as Cofactors for GATA3

Ono, Y., Fukuhara, N., & Yoshie, O. (1998) · Molecular and Cellular Biology · doi:10.1128/mcb.18.12.6939 · Cited by 142 · see citing works

An SCL 3’ enhancer targets developing endothelium together with embryonic and adult haematopoietic progenitors

Sánchez, M. J., Göttgens, B., Sinclair, A. M., Stanley, M. L., Begley, C. G., Hunter, S., & Green, A. R. (1999) · Development · doi:10.1242/dev.126.17.3891 · Cited by 134 · see citing works

Different sequence requirements for expression in erythroid and megakaryocytic cells within a regulatory element upstream of the GATA-1 gene

Vyas, P., McDevitt, M. A., Cantor, A. B., Katz, S. G., Fujiwara, Y., & Orkin, S. H. (1999) · Development · doi:10.1242/dev.126.12.2799 · Cited by 132 · see citing works

Adult and embryonic blood and endothelium derive from distinct precursor populations which are differentially programmed by BMP inXenopus

Walmsley, M. E., Ciau‐Uitz, A., & Patient, R. K. (2002) · Development · doi:10.1242/dev.00169 · Cited by 122 · see citing works

The SCL transcriptional network and BMP signaling pathway interact to regulate RUNX1 activity

Pimanda, J. E., Donaldson, I. J., Bruijn, M. F. T. R. D., Kinston, S., Knezevic, K., Huckle, L., Piltz, S., Landry, J., Green, A. R., Tannahill, D., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0607196104 · Cited by 118 · see citing works

Distinct 5′ SCL Enhancers Direct Transcription to Developing Brain, Spinal Cord, and Endothelium: Neural Expression Is Mediated by GATA Factor Binding Sites

Sinclair, A. M., Göttgens, B., Barton, L. M., Stanley, M. L., Pardanaud, L., Klaine, M., Gering, M., Bahn, S., Sánchez, M. J., Bench, A. J., et al. (1999) · Developmental Biology · doi:10.1006/dbio.1999.9236 · Cited by 105 · see citing works

AGata2intronic enhancer confers its pan-endothelia-specific regulation

Khandekar, M. J., Brandt, W. D., Zhou, Y., Dagenais, S. L., Glover, T. W., Suzuki, N., Shimizu, R., Yamamoto, M. P., Lim, K.-C., & Engel, J. D. (2007) · Development · doi:10.1242/dev.001297 · Cited by 92 · see citing works

The paralogous hematopoietic regulators Lyl1 and Scl are coregulated by Ets and GATA factors, but Lyl1 cannot rescue the early Scl–/– phenotype

Chan, W. Y. I., Follows, G., Lacaud, G., Pimanda, J. E., Landry, J., Kinston, S., Knezevic, K., Piltz, S., Donaldson, I. J., Gambardella, L., et al. (2006) · Blood · doi:10.1182/blood-2006-05-023226 · Cited by 79 · see citing works

Genome-wide identification of cis -regulatory sequences controlling blood and endothelial development

Donaldson, I. J., Chapman, M., Kinston, S., Landry, J., Knezevic, K., Piltz, S., Buckley, N. J., Green, A. R., & Göttgens, B. (2005) · Human Molecular Genetics · doi:10.1093/hmg/ddi056 · Cited by 78 · see citing works

Selective rescue of early haematopoietic progenitors in Scl –/– mice by expressing Scl under the control of a stem cell enhancer

Sánchez, M. J., Bockamp, E., Miller, J., Gambardella, L., & Green, A. R. (2001) · Development · doi:10.1242/dev.128.23.4815 · Cited by 77 · see citing works

GATA Motifs Regulate Early Hematopoietic Lineage-Specific Expression of the Gata2 Gene

Kobayashi‐Osaki, M., Ohneda, O., Suzuki, N., Minegishi, N., Yokomizo, T., Takahashi, S., Lim, K.-C., Engel, J. D., & Yamamoto, M. P. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.16.7005-7020.2005 · Cited by 75 · see citing works

The emergence of definitive hematopoietic stem cells in the mammal

Dzierzak, E. A. (2005) · Current Opinion in Hematology · doi:10.1097/01.moh.0000160736.44726.0e · Cited by 59 · see citing works

Context-dependent GATA Factor Function

Wozniak, R. J., Boyer, M. E., Grass, J. A., Lee, Y., & Bresnick, E. H. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m700792200 · Cited by 57 · see citing works

An Oct-1 binding site mediates activation of the gata2 promoter by BMP signaling

Oren, T. (2005) · Nucleic Acids Research · doi:10.1093/nar/gki746 · Cited by 28 · see citing works

Two new Drosophila genes related to human hematopoietic and neurogenic transcription factors.

Varterasian, M. L., Lipkowitz, S., Karsch‐Mizrachi, I., Paterson, B. M., & Kirsch, I. R. (1993) · PubMed · Cited by 12 · see citing works

From haematopoietic stem cells to complex differentiation landscapes

Laurenti, E., & Göttgens, B. (2018) · Nature · doi:10.1038/nature25022 · Cited by 830 · see citing works

Combinatorial transcriptional control in blood stem/progenitor cells: genome-wide analysis of ten major transcriptional regulators

Wilson, N. K., Foster, S. D., Wang, X., Knezevic, K., Schütte, J., Kaimakis, P., Chilarska, P. M., Kinston, S., Ouwehand, W. H., Dzierzak, E., et al. (2010) · Cell stem cell · doi:10.1016/j.stem.2010.07.016 · Cited by 728 · see citing works

Emerging properties of animal gene regulatory networks

Davidson, E. H. (2010) · Nature · doi:10.1038/nature09645 · Cited by 579 · see citing works

Evolution of Gene Regulatory Networks Controlling Body Plan Development

Peter, I. S., & Davidson, E. H. (2011) · Cell · doi:10.1016/j.cell.2011.02.017 · Cited by 417 · see citing works

Decoding the regulatory network of early blood development from single-cell gene expression measurements

Moignard, V., Woodhouse, S., Haghverdi, L., Lilly, A. J., Tanaka, Y., Wilkinson, A. C., Buettner, F., Macaulay, I. C., Jawaid, W., Diamanti, E., et al. (2015) · Nature Biotechnology · doi:10.1038/nbt.3154 · Cited by 380 · see citing works

Transcriptional Control of Endothelial Cell Development

De Val, S., & Black, B. L. (2009) · Developmental Cell · doi:10.1016/j.devcel.2009.01.014 · Cited by 346 · see citing works

Genome-wide Analysis of Simultaneous GATA1/2, RUNX1, FLI1, and SCL Binding in Megakaryocytes Identifies Hematopoietic Regulators

Tijssen, M. R., Cvejic, A., Joshi, A., Hannah, R., Ferreira, R., Forrai, A., Bellissimo, D. C., Oram, S. H., Smethurst, P. A., Wilson, N. K., et al. (2011) · Developmental Cell · doi:10.1016/j.devcel.2011.04.008 · Cited by 283 · see citing works

Loss-of-function germline GATA2 mutations in patients with MDS/AML or MonoMAC syndrome and primary lymphedema reveal a key role for GATA2 in the lymphatic vasculature

Kazenwadel, J., Secker, G. A., Liu, Y. J., Rosenfeld, J. A., Wildin, R. S., Cuellar‐Rodríguez, J., Hsu, A. P., Dyack, S., Fernandez, C. V., Chong, C., et al. (2011) · Blood · doi:10.1182/blood-2011-08-374363 · Cited by 275 · see citing works

Transcriptional and epigenomic landscapes of CNS and non-CNS vascular endothelial cells

Sabbagh, M. F., Heng, J. S., Luo, C., Castanon, R. G., Nery, J. R., Rattner, A., Goff, L. A., Ecker, J. R., & Nathans, J. (2018) · eLife · doi:10.7554/elife.36187 · Cited by 245 · see citing works

The transcription factor Erg is essential for definitive hematopoiesis and the function of adult hematopoietic stem cells

Loughran, S. J., Kruse, E., Hacking, D. F., de Graaf, C. A., Hyland, C. D., Willson, T. A., Henley, K. J., Ellis, S. L., Voss, A. K., Metcalf, D., et al. (2008) · Nature Immunology · doi:10.1038/ni.1617 · Cited by 265 · see citing works

Characterisation of transcriptional networks in blood stem and progenitor cells using high-throughput single cell gene expression analysis

Moignard, V., Macaulay, I., Swiers, G., Buettner, F., Schütte, J., Calero-Nieto, F., Kinston, S., Joshi, A., Hannah, R., Theis, F. J., et al. (2013) · Nature Cell Biology · doi:10.1038/ncb2709 · Cited by 116 · see citing works

GATA2 haploinsufficiency caused by mutations in a conserved intronic element leads to MonoMAC syndrome

Hsu, A. P., Johnson, K. D., Falcone, E. L., Sanalkumar, R., Sanchez, L. A., Hickstein, D. D., Cuellar‐Rodríguez, J., Lemieux, J. E., Zerbe, C. S., Bresnick, E. H., et al. (2013) · Blood · doi:10.1182/blood-2012-08-452763 · Cited by 246 · see citing works

Transcription factor networks in erythroid cell and megakaryocyte development

Doré, L. C., & Crispino, J. D. (2011) · Blood · doi:10.1182/blood-2011-04-285981 · Cited by 238 · see citing works

A Differential Wiring Analysis of Expression Data Correctly Identifies the Gene Containing the Causal Mutation

Hudson, N. J., Reverter, A., & Dalrymple, B. P. (2009) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1000382 · Cited by 221 · see citing works

Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming

Moreau, T., Evans, A., Vasquez, L. J., Tijssen, M. R., Yan, Y., Trotter, M. W. B., Howard, D. J., Colzani, M., Arumugam, M. Q., Wu, W. H., et al. (2016) · Nature Communications · doi:10.1038/ncomms11208 · Cited by 233 · see citing works

In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer

Chen, Z., Arai, E., Khan, O., Zhang, Z., Ngiow, S. F., He, Y. M., Huang, H., Manne, S., Cao, Z., Baxter, A. E., et al. (2021) · Cell · doi:10.1016/j.cell.2021.02.019 · Cited by 201 · see citing works

Definitive Hematopoiesis in the Yolk Sac Emerges from Wnt-Responsive Hemogenic Endothelium Independently of Circulation and Arterial Identity

Frame, J. M., Fegan, K. H., Conway, S. J., McGrath, K. E., & Palis, J. (2015) · Stem Cells · doi:10.1002/stem.2213 · Cited by 192 · see citing works

Direct induction of haematoendothelial programs in human pluripotent stem cells by transcriptional regulators

Elcheva, I. A., Brok-Volchanskaya, V. S., Kumar, A., Liu, P., Lee, J. H., Tong, L., Vodyanik, M. A., Swanson, S. A., Stewart, R. M., Kyba, M., et al. (2014) · Nature Communications · doi:10.1038/ncomms5372 · Cited by 191 · see citing works

Fli1 Acts at the Top of the Transcriptional Network Driving Blood and Endothelial Development

Liu, F., Walmsley, M. E., Rodaway, A., & Patient, R. K. (2008) · Current Biology · doi:10.1016/j.cub.2008.07.048 · Cited by 182 · see citing works

Hierarchical Differentiation of Myeloid Progenitors Is Encoded in the Transcription Factor Network

Krumsiek, J., Marr, C., Schroeder, T., & Theis, F. J. (2011) · PLoS ONE · doi:10.1371/journal.pone.0022649 · Cited by 174 · see citing works

RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis

Lichtinger, M., Ingram, R., Hannah, R., Müller, D., Clarke, D., Assi, S. A., Lie‐A‐Ling, M., Noailles, L., Vijayabaskar, M. S., Wu, M., et al. (2012) · The EMBO Journal · doi:10.1038/emboj.2012.275 · Cited by 180 · see citing works

The role of the GATA2 transcription factor in normal and malignant hematopoiesis

Vicente, C., Conchillo, A., García-Sánchez, M. A., & Odero, M. D. (2011) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2011.04.007 · Cited by 174 · see citing works

Direct Reprogramming of Murine Fibroblasts to Hematopoietic Progenitor Cells

Batta, K., Florkowska, M., Kouskoff, V., & Lacaud, G. (2014) · Cell Reports · doi:10.1016/j.celrep.2014.11.002 · Cited by 169 · see citing works

Etv2/ER71 induces vascular mesoderm from Flk1+PDGFRα+ primitive mesoderm

Kataoka, H., Hayashi, M., Nakagawa, R., Tanaka, Y., Izumi, N., Nishikawa, S., Jakt, L. M., Tarui, H., & Nishikawa, S. (2011) · Blood · doi:10.1182/blood-2011-05-352658 · Cited by 166 · see citing works

Blood and immune development in human fetal bone marrow and Down syndrome

Jardine, L., Webb, S., Goh, I., Londoño, M. Q., Reynolds, G., Mather, M. W., Olabi, B., Stephenson, E., Botting, R. A., Horsfall, D., et al. (2021) · Nature · doi:10.1038/s41586-021-03929-x · Cited by 163 · see citing works

CD44, Hyaluronan, the Hematopoietic Stem Cell, and Leukemia-Initiating Cells

Zöller, M. (2015) · Frontiers in Immunology · doi:10.3389/fimmu.2015.00235 · Cited by 156 · see citing works

A Role for the Long Noncoding RNA SENCR in Commitment and Function of Endothelial Cells

Boulberdaa, M., Scott, E., Ballantyne, M. D., García, R., Descamps, B., Angelini, G. D., Brittan, M., Hunter, A., McBride, M., McClure, J., et al. (2016) · Molecular Therapy · doi:10.1038/mt.2016.41 · Cited by 153 · see citing works

E2A proteins maintain the hematopoietic stem cell pool and promote the maturation of myelolymphoid and myeloerythroid progenitors

Semerad, C. L., Mercer, E. M., Inlay, M. A., Weissman, I. L., & Murre, C. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0808866106 · Cited by 145 · see citing works

Adult Hematopoietic Stem and Progenitor Cells Require Either Lyl1 or Scl for Survival

Souroullas, G. P., Salmon, J. M., Sablitzky, F., Curtis, D. J., & Goodell, M. A. (2009) · Cell stem cell · doi:10.1016/j.stem.2009.01.001 · Cited by 137 · see citing works

Developmental hematopoiesis: Ontogeny, genetic programming and conservation

Ciau‐Uitz, A., Monteiro, R. M., Kirmizitas, A., & Patient, R. K. (2014) · Experimental Hematology · doi:10.1016/j.exphem.2014.06.001 · Cited by 138 · see citing works

Genome-wide analysis of transcriptional regulators in human HSPCs reveals a densely interconnected network of coding and noncoding genes

Beck, D., Thoms, J. A. I., Perera, D., Schütte, J., Unnikrishnan, A., Knezevic, K., Kinston, S. J., Wilson, N. K., O’Brien, T. A., Göttgens, B., et al. (2013) · Blood · doi:10.1182/blood-2013-03-490425 · Cited by 133 · see citing works

Recruitment and remodeling of an ancient gene regulatory network during land plant evolution

Pires, N. D., Yi, K., Breuninger, H., Catarino, B., Menand, B., & Dolan, L. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1305457110 · Cited by 137 · see citing works

SCL/TAL1: a multifaceted regulator from blood development to disease

Porcher, C., Chagraoui, H., & Kristiansen, M. S. (2017) · Blood · doi:10.1182/blood-2016-12-754051 · Cited by 135 · see citing works

Echinodermata: The Complex Immune System in Echinoderms

Smith, L. C., Arizza, V., Hudgell, M. A. B., Barone, G., Bodnar, A. G., Buckley, K. M., Cunsolo, V., Dheilly, N. M., Franchi, N., Fugmann, S. D., et al. (2018) · Springer eBooks · doi:10.1007/978-3-319-76768-0_13 · Cited by 131 · see citing works

Genome-Wide Analysis of the Zebrafish ETS Family Identifies Three Genes Required for Hemangioblast Differentiation or Angiogenesis

Liu, F., & Patient, R. K. (2008) · Circulation Research · doi:10.1161/circresaha.108.179713 · Cited by 128 · see citing works

The transcriptional program controlled by the stem cell leukemia gene Scl/Tal1 during early embryonic hematopoietic development

Wilson, N. K., Miranda‐Saavedra, D., Kinston, S., Bonadies, N., Foster, S. D., Calero‐Nieto, F. J., Dawson, M. A., Donaldson, I. J., Dumon, S., Frampton, J., et al. (2009) · Blood · doi:10.1182/blood-2009-01-200048 · Cited by 120 · see citing works

Early chromatin unfolding by RUNX1: a molecular explanation for differential requirements during specification versus maintenance of the hematopoietic gene expression program

Hoogenkamp, M., Lichtinger, M., Krysinska, H., Lancrin, C., Clarke, D., Williamson, A., Mazzarella, L., Ingram, R., Jorgensen, H., Fisher, A., et al. (2009) · Blood · doi:10.1182/blood-2008-11-191890 · Cited by 121 · see citing works

Single-cell transcriptomics reveal the dynamic of haematopoietic stem cell production in the aorta

Baron, C. S., Kester, L. A., Klaus, A., Boisset, J.-C., Thambyrajah, R., Yvernogeau, L., Kouskoff, V., Lacaud, G., van Oudenaarden, A., & Robin, C. (2018) · Nature Communications · doi:10.1038/s41467-018-04893-3 · Cited by 115 · see citing works

Endothelio-Mesenchymal Interaction Controls runx1 Expression and Modulates the notch Pathway to Initiate Aortic Hematopoiesis

Richard, C., Drevon, C., Canto, P., Villain, G., Bollérot, K., Lempereur, A., Teillet, M., Vincent, C., Rosselló, C. A., Torres, M., et al. (2013) · Developmental Cell · doi:10.1016/j.devcel.2013.02.011 · Cited by 116 · see citing works

Induction of hematopoietic and endothelial cell program orchestrated by ETS transcription factor ER71/ETV2

Liu, F., Li, D., Yu, Y. Y. L., Kang, I., Cha, M., Kim, J. Y., Park, C., Watson, D. K., Wang, T., & Choi, K. (2015) · EMBO Reports · doi:10.15252/embr.201439939 · Cited by 116 · see citing works

ERG dependence distinguishes developmental control of hematopoietic stem cell maintenance from hematopoietic specificationPreprint

Taoudi, S., Bee, T., Hilton, A. A., Knezevic, K., Scott, J. A., Willson, T. A., Collin, C., Thomas, T., Voss, A. K., Kile, B. T., et al. (2011) · Genes & Development · doi:10.1101/gad.2009211 · Cited by 112 · see citing works

Dual requirement for the ETS transcription factors Fli-1 and Erg in hematopoietic stem cells and the megakaryocyte lineage

Kruse, E., Loughran, S. J., Baldwin, T. M., Josefsson, E. C., Ellis, S. L., Watson, D. K., Nurden, P., Metcalf, D., Hilton, D. J., Alexander, W. S., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0906556106 · Cited by 110 · see citing works

Reconstructing blood stem cell regulatory network models from single-cell molecular profiles

Hamey, F., Nestorowa, S., Kinston, S., Kent, D. G., Wilson, N. K., & Göttgens, B. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1610609114 · Cited by 102 · see citing works

Understanding the Role of ETS-Mediated Gene Regulation in Complex Biological Processes

Findlay, V. J., LaRue, A. C., Turner, D. P., Watson, P. M., & Watson, D. K. (2013) · Advances in cancer research · doi:10.1016/b978-0-12-407190-2.00001-0 · Cited by 101 · see citing works

Discovery of microvascular miRNAs using public gene expression data: miR-145 is expressed in pericytes and is a regulator of Fli1

Larsson, E., Fuchs, P. F., Heldin, J., Barkefors, I., Bondjers, C., Genové, G., Arrondel, C., Gerwins, P., Kurschat, C. E., Schermer, B., et al. (2009) · Genome Medicine · doi:10.1186/gm108 · Cited by 93 · see citing works

Hard-wired heterogeneity in blood stem cells revealed using a dynamic regulatory network model

Bonzanni, N., Garg, A. D., Feenstra, K. A., Schütte, J., Kinston, S., Miranda‐Saavedra, D., Heringa, J., Xénarios, I., & Göttgens, B. (2013) · Bioinformatics · doi:10.1093/bioinformatics/btt243 · Cited by 92 · see citing works

Perturbation of gut bacteria induces a coordinated cellular immune response in the purple sea urchin larva

Ho, E. C. H., Buckley, K. M., Schrankel, C. S., Schuh, N. W., Hibino, T., Solek, C. M., Bae, K., Wang, G., & Rast, J. P. (2016) · Immunology and Cell Biology · doi:10.1038/icb.2016.51 · Cited by 90 · see citing works

Dynamic Analysis of Gene Expression and Genome-wide Transcription Factor Binding during Lineage Specification of Multipotent Progenitors

May, G. E., Soneji, S., Tipping, A. J., Teles, J., McGowan, S. J., Wu, M., Guo, Y., Fugazza, C., Brown, J., Karlsson, G., et al. (2013) · Cell stem cell · doi:10.1016/j.stem.2013.09.003 · Cited by 88 · see citing works

Differentiation-dependent interactions between RUNX-1 and FLI-1 during megakaryocyte development.

Huang, H., Yu, M., Akie, T. E., Moran, T. B., Woo, A. J., Tu, N., Waldon, Z., Lin, Y. Y., Steen, H., & Cantor, A. B. (2009) · Molecular and Cellular Biology · doi:10.1128/mcb.00090-09 · Cited by 87 · see citing works

Assessing regulatory information in developmental gene regulatory networks

Peter, I. S., & Davidson, E. H. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1610616114 · Cited by 86 · see citing works

Hematopoietic stem cell emergence in the conceptus and the role of Runx1

Swiers, G., Bruijn, M. F. T. R. D., & Speck, N. A. (2010) · The International Journal of Developmental Biology · doi:10.1387/ijdb.103106gs · Cited by 85 · see citing works

Overlapping Requirements for Tet2 and Tet3 in Normal Development and Hematopoietic Stem Cell Emergence

Li, C., Lan, Y., Schwartz-Orbach, L., Korol, E., Tahiliani, M., Evans, T., & Goll, M. G. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.07.025 · Cited by 80 · see citing works

GABP controls a critical transcription regulatory module that is essential for maintenance and differentiation of hematopoietic stem/progenitor cells

Yu, S., Cui, K., Jothi, R., Zhao, D., Jing, X., Zhao, K., & Xue, H. (2010) · Blood · doi:10.1182/blood-2010-09-306563 · Cited by 82 · see citing works

Common features of megakaryocytes and hematopoietic stem cells: What's the connection?

Huang, H., & Cantor, A. B. (2009) · Journal of Cellular Biochemistry · doi:10.1002/jcb.22184 · Cited by 79 · see citing works

Expression of the leukemia oncogene Lmo2 is controlled by an array of tissue-specific elements dispersed over 100 kb and bound by Tal1/Lmo2, Ets, and Gata factors

Landry, J., Bonadies, N., Kinston, S., Knezevic, K., Wilson, N. K., Oram, S. H., Janes, M. E., Piltz, S., Hammett, M., Carter, J., et al. (2009) · Blood · doi:10.1182/blood-2008-11-187757 · Cited by 75 · see citing works

Diversification of oral and aboral mesodermal regulatory states in pregastrular sea urchin embryos

Materna, S. C., Ransick, A., Li, E., & Davidson, E. H. (2012) · Developmental Biology · doi:10.1016/j.ydbio.2012.11.033 · Cited by 72 · see citing works

An ancient role for Gata-1/2/3 and Scl transcription factor homologs in the development of immunocytes

Solek, C. M., Oliveri, P., Loza‐Coll, M., Schrankel, C. S., Ho, E. C. H., Wang, G., & Rast, J. P. (2013) · Developmental Biology · doi:10.1016/j.ydbio.2013.06.019 · Cited by 72 · see citing works

ETS transcription factors in hematopoietic stem cell development

Ciau‐Uitz, A., Wang, L., Patient, R. K., & Liu, F. (2013) · Blood Cells Molecules and Diseases · doi:10.1016/j.bcmd.2013.07.010 · Cited by 70 · see citing works

Sox7-sustained expression alters the balance between proliferation and differentiation of hematopoietic progenitors at the onset of blood specification

Gandillet, A., Serrano, A. G., Pearson, S., Lie‐A‐Ling, M., Lacaud, G., & Kouskoff, V. (2009) · Blood · doi:10.1182/blood-2009-06-226290 · Cited by 67 · see citing works

Cooperative interaction of Etv2 and Gata2 regulates the development of endothelial and hematopoietic lineages

Shi, X., Richard, J. J., Zirbes, K. M., Gong, W., Lin, G., Kyba, M., Thomson, J., Koyano‐Nakagawa, N., & Garry, D. J. (2014) · Developmental Biology · doi:10.1016/j.ydbio.2014.02.018 · Cited by 65 · see citing works

Gfi1 Expression Is Controlled by Five Distinct Regulatory Regions Spread over 100 Kilobases, with Scl/Tal1, Gata2, PU.1, Erg, Meis1, and Runx1 Acting as Upstream Regulators in Early Hematopoietic Cells

Wilson, N. K., Timms, R. T., Kinston, S., Cheng, Y.-H., Oram, S. H., Landry, J., Mullender, J. L., Ottersbach, K., & Göttgens, B. (2010) · Molecular and Cellular Biology · doi:10.1128/mcb.00032-10 · Cited by 65 · see citing works

ETS-dependent regulation of a distal Gata4 cardiac enhancer

Schachterle, W., Rojas, A., Xu, S.-M., & Black, B. L. (2011) · Developmental Biology · doi:10.1016/j.ydbio.2011.10.023 · Cited by 64 · see citing works

An experimentally validated network of nine haematopoietic transcription factors reveals mechanisms of cell state stability

Schütte, J., Wang, H., Antoniou, S., Jarratt, A., Wilson, N. K., Riepsaame, J., Calero-Nieto, F. J., Moignard, V., Basilico, S., Kinston, S. J., et al. (2016) · eLife · doi:10.7554/elife.11469 · Cited by 63 · see citing works

GPR126 Protein Regulates Developmental and Pathological Angiogenesis through Modulation of VEGFR2 Receptor Signaling

Cui, H., Wang, Y., Huang, H., Yu, W., Bai, M., Zhang, L., Bryan, B. A., Wang, Y., Luo, J., Li, D., et al. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.571000 · Cited by 63 · see citing works

Molecular Hallmarks of Endogenous Chromatin Complexes Containing Master Regulators of Hematopoiesis

Wozniak, R. J., Keleş, S., Lugus, J. J., Young, K. H., Boyer, M. E., Tran, T. M., Choi, K., & Bresnick, E. H. (2008) · Molecular and Cellular Biology · doi:10.1128/mcb.01061-08 · Cited by 63 · see citing works

SCL/TAL1 in Hematopoiesis and Cellular Reprogramming

Hoang, T., Lambert, J. A., & Martin, R. (2016) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/bs.ctdb.2016.01.004 · Cited by 62 · see citing works

Learning causal networks with latent variables from multivariate information in genomic data

Verny, L., Sella, N., Affeldt, S., Singh, P. P., & Isambert, H. (2017) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1005662 · Cited by 63 · see citing works

Transcriptional Regulation of Haematopoietic Stem Cells

Wilkinson, A. C., & Göttgens, B. (2013) · Advances in experimental medicine and biology · doi:10.1007/978-94-007-6621-1_11 · Cited by 58 · see citing works

The Flk1-Cre-Mediated Deletion of ETV2 Defines Its Narrow Temporal Requirement During Embryonic Hematopoietic Development

Wareing, S., Mazan, A., Pearson, S., Göttgens, B., Lacaud, G., & Kouskoff, V. (2012) · Stem Cells · doi:10.1002/stem.1115 · Cited by 58 · see citing works

Genome-wide transcription factor–binding maps reveal cell-specific changes in the regulatory architecture of human HSPCs

Subramanian, S., Thoms, J. A. I., Huang, Y., Cornejo-Páramo, P., Koch, F. C., Jacquelin, S., Shen, S., Song, E., Joshi, S., Brownlee, C., et al. (2023) · Blood · doi:10.1182/blood.2023021120 · Cited by 57 · see citing works

Modeling Reveals Bistability and Low-Pass Filtering in the Network Module Determining Blood Stem Cell Fate

Narula, J., Smith, A. M., Göttgens, B., & Igoshin, O. A. (2010) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1000771 · Cited by 56 · see citing works

The evolutionary origins of chordate hematopoiesis and vertebrate endothelia

Pascual‐Anaya, J., Albuixech-Crespo, B., Somorjai, I., Carmona, R., Oisi, Y., Álvarez, S., Kuratani, S., Muñoz‐Chápuli, R., & García‐Fernàndez, J. (2012) · Developmental Biology · doi:10.1016/j.ydbio.2012.11.015 · Cited by 57 · see citing works

Genetic control of hematopoietic development in Xenopus and zebrafish

Ciau‐Uitz, A., Liu, F., & Patient, R. K. (2010) · The International Journal of Developmental Biology · doi:10.1387/ijdb.093055ac · Cited by 55 · see citing works

Gene regulatory networks governing haematopoietic stem cell development and identity

Pimanda, J. E., & Göttgens, B. (2010) · The International Journal of Developmental Biology · doi:10.1387/ijdb.093038jp · Cited by 55 · see citing works

Genome-scale expression and transcription factor binding profiles reveal therapeutic targets in transgenic ERG myeloid leukemia

Goldberg, L., Tijssen, M. R., Birger, Y., Hannah, R., Kinston, S., Schütte, J., Beck, D., Knezevic, K., Schiby, G., Jacob‐Hirsch, J., et al. (2013) · Blood · doi:10.1182/blood-2013-01-477133 · Cited by 54 · see citing works

A method to identify and analyze biological programs through automated reasoning

Yordanov, B., Dunn, S.-J., Kugler, H., Smith, A. G., Martello, G., & Emmott, S. (2016) · npj Systems Biology and Applications · doi:10.1038/npjsba.2016.10 · Cited by 54 · see citing works

Context-dependent function of “GATA switch” sites in vivo

Snow, J. W., Trowbridge, J. J., Johnson, K. D., Fujiwara, T., Emambokus, N. E., Grass, J. A., Orkin, S. H., & Bresnick, E. H. (2011) · Blood · doi:10.1182/blood-2010-10-313031 · Cited by 53 · see citing works

Dynamic HoxB4-regulatory network during embryonic stem cell differentiation to hematopoietic cells

Fan, R., Bonde, S., Gao, P., Sotomayor, B., Chen, C., Mouw, T. J., Zavazava, N., & Tan, K. (2012) · Blood · doi:10.1182/blood-2011-12-396754 · Cited by 52 · see citing works

A Single cis Element Maintains Repression of the Key Developmental Regulator Gata2

Snow, J. W., Trowbridge, J. J., Fujiwara, T., Emambokus, N. E., Grass, J. A., Orkin, S. H., & Bresnick, E. H. (2010) · PLoS Genetics · doi:10.1371/journal.pgen.1001103 · Cited by 52 · see citing works

The Hemogenic Competence of Endothelial Progenitors Is Restricted by Runx1 Silencing during Embryonic Development

Eliades, A., Wareing, S., Marinopoulou, E., Fadlullah, M. Z. H., Patel, R., Grabarek, J. B., Płusa, B., Lacaud, G., & Kouskoff, V. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.05.001 · Cited by 50 · see citing works

Transcriptional regulatory network controlling the ontogeny of hematopoietic stem cellsPreprint

Gao, P., Chen, C., Howell, E. D., Li, Y., Tober, J. M., Uzun, Y., He, B., Gao, L., Zhu, Q., Siekmann, A. F., et al. (2020) · Genes & Development · doi:10.1101/gad.338202.120 · Cited by 47 · see citing works

In vivo clonal tracking reveals evidence of haemangioblast and haematomesoblast contribution to yolk sac haematopoiesis

Biben, C., Weber, T. S., Potts, K. S., Choi, J., Miles, D. C., Carmagnac, A., Sargeant, T., de Graaf, C. A., Fennell, K. A., Farley, A., et al. (2023) · Nature Communications · doi:10.1038/s41467-022-35744-x · Cited by 46 · see citing works

A compendium of genome-wide hematopoietic transcription factor maps supports the identification of gene regulatory control mechanisms

Hannah, R., Joshi, A., Wilson, N. K., Kinston, S., & Göttgens, B. (2011) · Experimental Hematology · doi:10.1016/j.exphem.2011.02.009 · Cited by 47 · see citing works

The transcriptional programme controlled by Runx1 during early embryonic blood development

Tanaka, Y., Joshi, A., Wilson, N. K., Kinston, S., Nishikawa, S., & Göttgens, B. (2012) · Developmental Biology · doi:10.1016/j.ydbio.2012.03.024 · Cited by 46 · see citing works

VEGFA-dependent and -independent pathways synergise to drive Scl expression and initiate programming of the blood stem cell lineage in Xenopus

Ciau‐Uitz, A., Pinheiro, P., Kirmizitas, A., Zuo, J., & Patient, R. K. (2013) · Development · doi:10.1242/dev.090829 · Cited by 44 · see citing works

Disruption of a GATA2-TAL1-ERG regulatory circuit promotes erythroid transition in healthy and leukemic stem cells

Thoms, J. A. I., Truong, P., Subramanian, S., Knezevic, K., Harvey, G., Huang, Y., Seneviratne, J. A., Carter, D. R., Joshi, S. M., Skhinas, J. N., et al. (2021) · Blood · doi:10.1182/blood.2020009707 · Cited by 41 · see citing works

A previously unrecognized promoter of LMO2 forms part of a transcriptional regulatory circuit mediating LMO2 expression in a subset of T-acute lymphoblastic leukaemia patients

Oram, S., Thoms, J., Pridans, C., Janes, M. E., Kinston, S., Anand, S., Landry, J., Lock, R. B., Jayaraman, P.-S., Huntly, B., et al. (2010) · Oncogene · doi:10.1038/onc.2010.320 · Cited by 48 · see citing works

Endoglin expression in blood and endothelium is differentially regulated by modular assembly of the Ets/Gata hemangioblast code

Pimanda, J. E., Chan, W. Y. I., Wilson, N. K., Smith, A. M., Kinston, S., Knezevic, K., Janes, M. E., Landry, J., Kolb‐Kokocinski, A., Frampton, J., et al. (2008) · Blood · doi:10.1182/blood-2008-05-157560 · Cited by 43 · see citing works

PKA/CREB Signaling Triggers Initiation of Endothelial and Hematopoietic Cell Differentiation via Etv2 Induction

Yamamizu, K., Matsunaga, T., Katayama, S., Kataoka, H., Takayama, N., Eto, K., Nishikawa, S., & Yamashita, J. K. (2012) · Stem Cells · doi:10.1002/stem.1041 · Cited by 42 · see citing works

A critical role for endoglin in the emergence of blood during embryonic development

Borges, L., Iacovino, M., Mayerhofer, T., Koyano‐Nakagawa, N., Baik, J., Garry, D. J., Kyba, M., Letarte, M., & Perlingeiro, R. C. R. (2012) · Blood · doi:10.1182/blood-2011-11-391896 · Cited by 42 · see citing works

Gene Networks of Fully Connected Triads with Complete Auto-Activation Enable Multistability and Stepwise Stochastic Transitions

Faucon, P. C., Pardee, K., Kumar, R., Li, H., Loh, Y., & Wang, X. (2014) · PLoS ONE · doi:10.1371/journal.pone.0102873 · Cited by 41 · see citing works

Transcriptional regulation of haematopoietic transcription factors

Wilson, N. K., Calero‐Nieto, F. J., Ferreira, R., & Göttgens, B. (2011) · Stem Cell Research & Therapy · doi:10.1186/scrt47 · Cited by 41 · see citing works

Developmental disorders caused by haploinsufficiency of transcriptional regulators: a perspective based on cell fate determination

Zug, R. (2022) · Biology Open · doi:10.1242/bio.058896 · Cited by 42 · see citing works

Immune-related zinc finger gene ZFAT is an essential transcriptional regulator for hematopoietic differentiation in blood islands

Tsunoda, T., Takashima, Y., Tanaka, Y., Fujimoto, T., Doi, K., Hirose, Y., Koyanagi, M., Yoshida, Y., Okamura, T., Kuroki, M., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1002494107 · Cited by 40 · see citing works

Mesodermal patterning activity of SCL

Ismailoglu, I., Yeamans, G., Daley, G. Q., Perlingeiro, R. C. R., & Kyba, M. (2008) · Experimental Hematology · doi:10.1016/j.exphem.2008.07.005 · Cited by 39 · see citing works

Transcription factor‐mediated reprogramming toward hematopoietic stem cells

Ebina, W., & Rossi, D. J. (2015) · The EMBO Journal · doi:10.15252/embj.201490804 · Cited by 38 · see citing works

ETS Transcription Factor ETV2/ER71/Etsrp in Hematopoietic and Vascular Development

Sumanas, S., & Choi, K. (2016) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/bs.ctdb.2016.01.005 · Cited by 39 · see citing works

Functional and molecular characterization of mouse Gata2-independent hematopoietic progenitors

Kaimakis, P., de Pater, E., Eich, C., Kartalaei, P. S., Kauts, M., Vink, C. S., van der Linden, R., Jaegle, M., Yokomizo, T., Meijer, D., et al. (2016) · Blood · doi:10.1182/blood-2015-10-673749 · Cited by 37 · see citing works

A Computational Model of the Endothelial to Mesenchymal Transition

Weinstein, N., Mendoza, L., & Alvarez-Buylla, E. R. (2020) · Frontiers in Genetics · doi:10.3389/fgene.2020.00040 · Cited by 39 · see citing works

Transcription factors regulating vasculogenesis and angiogenesis

Payne, S., Neal, A., & Val, S. D. (2023) · Developmental Dynamics · doi:10.1002/dvdy.575 · Cited by 45 · see citing works

Genetic regulatory networks programming hematopoietic stem cells and erythroid lineage specification

Swiers, G., Patient, R., & Loose, M. (2006) · Developmental Biology · doi:10.1016/j.ydbio.2006.02.051 · Cited by 168 · see citing works

Establishing the transcriptional programme for blood: the SCL stem cell enhancer is regulated by a multiprotein complex containing Ets and GATA factors

Göttgens, B., Nastos, A., Kinston, S., Piltz, S., Delabesse, E. C. M., Stanley, M., Sanchez, M., Ciau‐Uitz, A., Patient, R., & Green, A. R. (2002) · The EMBO Journal · doi:10.1093/emboj/cdf286 · Cited by 212 · see citing works

Mathematical model of a gene regulatory network reconciles effects of genetic perturbations on hematopoietic stem cell emergence

Narula, J., Williams, C. J., Tiwari, A., Marks-Bluth, J., Pimanda, J. E., & Igoshin, O. A. (2013) · Developmental Biology · doi:10.1016/j.ydbio.2013.04.016 · Cited by 23 · see citing works

Runx1-mediated hematopoietic stem-cell emergence is controlled by a Gata/Ets/SCL-regulated enhancer

Nottingham, W. T., Jarratt, A., Burgess, M. O., Speck, C. L., Cheng, J., Prabhakar, S., Rubin, E., Li, P.-S., Sloane‐Stanley, J., Kong-a-San, J., et al. (2007) · Blood · doi:10.1182/blood-2007-07-100883 · Cited by 249 · see citing works

GATA Motifs Regulate Early Hematopoietic Lineage-Specific Expression of the Gata2 Gene

Kobayashi‐Osaki, M., Ohneda, O., Suzuki, N., Minegishi, N., Yokomizo, T., Takahashi, S., Lim, K.-C., Engel, J. D., & Yamamoto, M. P. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.16.7005-7020.2005 · Cited by 75 · see citing works