Cited by 311Hearing, Cochlea, Tinnitus, GeneticsNeuroscience and Music PerceptionHearing Loss and Rehabilitation

Listening to tailor-made notched music reduces tinnitus loudness and tinnitus-related auditory cortex activity

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Okamoto, Hidehiko, Stracke, Henning, Stoll, Wolfgang, Pantev, Christo·2010·Proceedings of the National Academy of Sciences

Abstract

Maladaptive auditory cortex reorganization may contribute to the generation and maintenance of tinnitus. Because cortical organization can be modified by behavioral training, we attempted to reduce tinnitus loudness by exposing chronic tinnitus patients to self-chosen, enjoyable music, which was modified (“notched”) to contain no energy in the frequency range surrounding the individual tinnitus frequency. After 12 months of regular listening, the target patient group ( n = 8) showed significantly reduced subjective tinnitus loudness and concomitantly exhibited reduced evoked activity in auditory cortex areas corresponding to the tinnitus frequency compared to patients who had received an analogous placebo notched music treatment ( n = 8). These findings indicate that tinnitus loudness can be significantly diminished by an enjoyable, low-cost, custom-tailored notched music treatment, potentially via reversing maladaptive auditory cortex reorganization.

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Crossref · 10.1073/pnas.0911268107

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Authors
Okamoto, H., Stracke, H., Stoll, W., & Pantev, C.
Affiliations
  • University of Münster (DE)
  • University Hospital Münster (DE)
Corresponding author
Pantev, Christo
Venue
Proceedings of the National Academy of Sciences
Published
2009-12-28
Volume
107
Issue
3
Pages
1207-1210
ISSN
  • 0027-8424 (ISSN-L)
  • 1091-6490
OpenAlex
W2135640921
Cited by
311
References
50
Citations by year
2026: 10 · 2025: 13 · 2024: 18 · 2023: 51 · 2022: 16 · 2021: 18 · 2020: 19 · 2019: 22 · 2018: 14 · 2017: 11 · 2016: 10 · 2015: 16 · 2014: 17 · 2013: 18 · 2012: 31
FWCI
9.22
Type
journal article
Language
en
Open access
Locations
  • Proceedings of the National Academy of Sciences (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Funders
Deutsche Forschungsgemeinschaft (Pa 392/10-3)
Topics
  • Life Sciences › Neuroscience › Sensory Systems › Hearing, Cochlea, Tinnitus, Genetics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neuroscience and Music Perception
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Hearing Loss and Rehabilitation
Keywords
tinnitus, tinnitus loudness, auditory cortex reorganization, music listening, tinnitus frequency, placebo-controlled intervention
MeSH terms
Adolescent, Adult, Auditory Cortex, Evoked Potentials, Auditory, Humans, Middle Aged, Music Therapy, Placebos, Tinnitus, Young Adult

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