“Control” laboratory rodents are metabolically morbid: Why it matters

Global Prevalence of Diabetes

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Inflammation and metabolic disorders

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Prevalence and Trends in Obesity Among US Adults, 1999-2008

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Inflammation and insulin resistance

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Mutation of the mouse klotho gene leads to a syndrome resembling ageing

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The Effect of Retarded Growth Upon the Length of Life Span and Upon the Ultimate Body Size

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Reversal of Obesity- and Diet-Induced Insulin Resistance with Salicylates or Targeted Disruption of Ikkβ

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The impact of physical activity on physical performance, mitochondrial bioenergetics, ROS production and calcium handling across the human adult lifespanPreprint

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Age-Dependent Mechanisms of Cardiac Hypertrophy Regression Following Exercise in Female MicePreprint

Leinwand, L. A., & Crocini, C. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.04.07.647563 · Cited by 2

Pharmacological agents and injection stress, but not social isolation, alter cognitive judgement bias in the mouse touchscreen operant chamber

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Isolation, validation, and long-term culture of mouse ear fibroblasts

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Securing reliability and validity in biomedical research: an essential task

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Playtime Prevents Obesity by Brain-Mediated Fat Browning

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Preclinical and Clinical Research on Oleogels

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Cellular Adaptations to Intermittent Fasting with Emphasis on the Brain

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Protein restriction does not affect body temperature pattern in female mice

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Role of prefrontal cortex and cholinergic modulation in attentional performance in rats

Fisher, B. M. (2017) · Apollo (University of Cambridge) · doi:10.17863/cam.21750 · Cited by 1

3Rs considerations when using ageing animals in science

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The laboratory rat

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The Cognitive Effects of Naturally Occurring Domoic Acid Toxicosis in Wild California Sea Lions (Zalophus Californianus)

Cook, P. F. (2013) · eScholarship (California Digital Library)

Food Restriction and the Accumulation of Fat in the Livers of Wistar Rats

de Moura, L. P. (2012) · The Open Nutrition Journal · doi:10.2174/1874288201206010035

Challenges in Endocrinology: Moving from the Post-Genomic Era, into the Nano-World and Beyond

Holly, J. M. P. (2011) · Frontiers in Endocrinology · doi:10.3389/fendo.2010.00011

AReversibleEarlyOxidizedRedoxStateThatPrecedes MacromolecularROSDamageinAgingNontransgenicand 3xTg-ADMouseNeurons

Brewer, G. J. (2012)

On the definition of the healthiest body weight for children and adults

Lorenzini, A. (2014) · Annales Kinesiologiae · doi:10.35469/ak.2014.33

Performance física e hipertrofia ventricular relacionada ao treinamento aeróbico contínuo e intervalado em ratos

de Abreu, E. S., Alves, J. O., dos Santos, A. C. C., Soares Marreiros Ferraz, A., & Ceccatto, V. M. (2024) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) · doi:10.5281/zenodo.14532643

Refinement Alternatives: Minimizing Pain and Distress in In Vivo Toxicity Testing

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Effects of exercise on neuroprotection in experimental autoimmune encephalomyelitis

Pryor, W. M. (2012)

Protocols Using Rodents to Model Eating Disorders in Humans

Rowland, N. E. (2019) · Methods in molecular biology · doi:10.1007/978-1-4939-9554-7_18

Environment is not trivial!

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Impacto del desarrollo de la línea tumoral A549 en el bienestar de ratones de la cepa N:NIH(S)-Fox1nu

Resasco, A. (2018) · El Servicio de Difusión de la Creación Intelectual (National University of La Plata) · doi:10.35537/10915/87590

Time-restricted feeding from adulthood to old age improves biconditional associative learning in geriatric rats regardless of macronutrient compositionPreprint

Hernandez, A. R., Federico, Q. P., & Burke, S. N. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.02.06.937532

L-GLUTAMINE SUPPLEMENTATION ASSOCIATED WITH MODERATE AEROBIC TRAINING IMPROVES BIOMETRIC, GLYCEMIC PROFILE AND THE ANTIOXIDANT DEFENSE

dos Santos, A. B., Beber, L. C. C., Basso, E. G. D. P., Goettems-Fiorin, P. B., Basso, R. D. B., Sulzbacher, M. M., Ludwig, M. S., & Heck, T. G. (2020) · Revista Contexto & Saúde · doi:10.21527/2176-7114.2020.39.62-77

Fizyoterapide Deney Hayvanlarının Kullanımı

Özcan, N. T., & Başkurt, Z. (2021) · Selçuk Tıp Dergisi · doi:10.30733/std.2021.01497

Similar qualitative and quantitative changes of mitochondrial respiration following strength and endurance training in normoxia and hypoxia in sedentary humans Pesta

Hoppel, Maček, Messner, Faulhaber, Kobel, Parson, Burtscher, Schocke, & Gnaiger (2011)

No chocolate, please! - Dioxin-induced responses in feeding related behaviour and in neuronal activity

Lensu, S. (2014) · STM:n Hallinnonalan avoin julkaisuarkisto (Julkari)

Faculty Opinions recommendation of Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study.

Kaeberlein, M. R. (2013) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.717953971.793461327

Further Reading

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Faculty Opinions recommendation of Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study.

Klip, A., & Pillon, N. J. (2012) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.717953971.793461957

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Metabotropic glutamate group II receptor activation in the dorsal striatum suppresses the motivation for cocaine in ratsPreprint

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A Swimming-Induced Zebrafish Exercise Apparatus for Versatile Training Approaches

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The Golden Hamster: A Valuable Model for Designing Cancer Therapies

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Incorporating farm animal models for the study of neuropsychiatric diseases: Expansion of the possibilities

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Laboratory mice are usually distressed and overweight, calling into question research findings

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¿Tomamos peores decisiones con el frigorífico a rebosar?

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Thermoneutrality Reveals True Cardiac Adaptations to Exercise, Disease, and Aging in Male Mice

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