Nitrate transport in salivary glands with implications for NO homeostasis
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Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans the biological, physical, and social sciences.
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Nitrite and nitrate are important protective elements of the oral and mucosal immune response, especially in settings of stress and periodontal injury.
“For instance, nitrite and nitrate are important protective elements of the oral and mucosal immune response, especially in settings of stress and periodontal injury[86,193,231].”
From Enterosalivary nitrate metabolism and the microbiome: Intersection of microbial metabolism, nitric oxide and diet in cardiac and pulmonary vascular health (2017) · cites this paper as [231]
In the setting of salivary gland dysfunction, there is a decrease in salivary nitrate concentration and corollary increase in urinary excretion, thereby reducing total body nitrate content and its enterosalivary circulation.
“In the setting of salivary gland dysfunction, there is a decrease in salivary nitrate concentration and corollary increase in urinary excretion, thereby reducing total body nitrate content and its enterosalivary circulation[84,193,231,293].”
From Enterosalivary nitrate metabolism and the microbiome: Intersection of microbial metabolism, nitric oxide and diet in cardiac and pulmonary vascular health (2017) · cites this paper as [231]
Nitrate content in saliva is highly regulated.
“Nitrate content in saliva is highly regulated[85,86,193,231].”
From Enterosalivary nitrate metabolism and the microbiome: Intersection of microbial metabolism, nitric oxide and diet in cardiac and pulmonary vascular health (2017) · cites this paper as [231]
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Another Way, Spectacular World
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- Authors
- Lundberg, J. O.
- Affiliations
- Karolinska Institutet (SE)
- Corresponding author
- Lundberg, Jon O.
- ORCID
- Lundberg, Jon O.
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 2012-07-31
- Volume
- 109
- Issue
- 33
- Pages
- 13144-13145
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- PMC
- PMC3421160
- OpenAlex
- W2149894315
- Cited by
- 49
- References
- 27
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 5 · 2023: 2 · 2022: 5 · 2021: 2 · 2020: 5 · 2019: 7 · 2018: 6 · 2017: 2 · 2016: 3 · 2015: 3 · 2014: 2 · 2013: 3 · 2012: 1
- FWCI
- 1.93
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Proceedings of the National Academy of Sciences (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Salivary Gland Disorders and Functions
- Health Sciences › Medicine › Physiology › Nitric Oxide and Endothelin Effects
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Ion Transport and Channel Regulation
- Keywords
- nitrate transport, salivary glands, nitric oxide homeostasis, nitric oxide, salivary nitrate, nitrate reductase, salivary flow
- MeSH terms
- Nitrate Transporters, Animals, Cell Membrane, Anion Transport Proteins, Organic Anion Transporters, Symporters
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