Mutational landscape of yeast mutator strains

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Modelling Mutation Spectra of Human Carcinogens Using Experimental Systems

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Preferential Protection of Genetic Fidelity within Open Chromatin by the Mismatch Repair Machinery

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Hypermutation signature reveals a slippage and realignment model of translesion synthesis by Rev3 polymerase in cisplatin-treated yeast

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A Case Study of Genomic Instability in an Industrial Strain of Saccharomyces cerevisiae

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Evolutionary Significance of Fungal Hypermutators: Lessons Learned from Clinical Strains and Implications for Fungal Plant Pathogens

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FKBP12-Dependent Inhibition of Calcineurin Mediates Immunosuppressive Antifungal Drug Action in Malassezia

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Defects in the GINS complex increase the instability of repetitive sequences via a recombination-dependent mechanism

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Dissecting genetic and environmental mutation signatures with model organisms

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The Eukaryotic Mismatch Recognition Complexes Track with the Replisome during DNA Synthesis

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Macrotene chromosomes provide insights to a new mechanism of high-order gene amplification in eukaryotes

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Mutation rate and spectrum in obligately outcrossing Caenorhabditis elegans mutation accumulation lines subjected to RNAi-induced knockdown of the mismatch repair gene msh-2

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Extremely Rare Polymorphisms in Saccharomyces cerevisiae Allow Inference of the Mutational Spectrum

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The response to the DNA damaging agent methyl methanesulfonate in a fungal plant pathogen

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DNA2 in Chromosome Stability and Cell Survival—Is It All about Replication Forks?

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A spontaneous mutation in DNA polymerase POL3 during in vitro passaging causes a hypermutator phenotype in Cryptococcus species

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Stability across the Whole Nuclear Genome in the Presence and Absence of DNA Mismatch Repair

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Ploidy and recombination proficiency shape the evolutionary adaptation to constitutive DNA replication stress

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Having a direct look: Analysis of DNA damage and repair mechanisms by next generation sequencing

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Analyzing Genome Rearrangements in Saccharomyces cerevisiae

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DNA damage response of major fungal pathogen Candida glabrata offers clues to explain its genetic diversity

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Heterogeneous Mutation Rates and Spectra in Yeast Hybrids

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Whole Genome Sequence Analysis of Mutations Accumulated in rad27 Δ Yeast Strains with Defects in the Processing of Okazaki Fragments Indicates Template-Switching Events

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Germline mutation: de novo mutation in reproductive lineage cells

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Complex mutation profiles in mismatch repair and ribonucleotide reductase mutants reveal novel repair substrate specificity of MutS homolog (MSH) complexes

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DNA lesions can frequently precede DNA:RNA hybrid accumulation

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Recombination in a sterile polyploid hybrid yeast upon meiotic Return-To-Growth

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Yeast mismatch repair components are required for stable inheritance of gene silencing

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Strain Development by Whole-Cell Directed Evolution

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Instability throughout the Saccharomyces cerevisiae genome resulting from Pms1 endonuclease deficiency

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Mechanisms of glycosylase induced genomic instability

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Phenotype switching of the mutation rate facilitates adaptive evolution

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Sequence Profiling of the Saccharomyces cerevisiae Genome Permits Deconvolution of Unique and Multialigned Reads for Variant Detection

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The fitness cost of mismatch repair mutators in Saccharomyces cerevisiae: partitioning the mutational load

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Navigating yeast genome maintenance with functional genomics

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Cooperation between non-essential DNA polymerases contributes to genome stability in Saccharomyces cerevisiae

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Mitochondrial activities play a pivotal role in regulating cell cycle in response to doxorubicin

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Comprehensive Mutational Landscape of Yeast Mutator Strains Reveals the Genetic Basis of Mutational Signatures in Cancer

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DNA polymerase δ: A single Pol31 polymorphism suppresses the strain background-specific lethality of Pol32 inactivation in Saccharomyces cerevisiae

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Genome instability footprint under rapamycin and hydroxyurea treatments

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Systematic Identification of Determinants for Single-Strand Annealing-Mediated Deletion Formation inSaccharomyces cerevisiae

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The Population Genetics of Ploidy Change in FungiPreprint

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Genetic diversity landscapes in outcrossing and selfing Caenorhabditis nematodesPreprint

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Stable hypermutators revealed by the genomic landscape of genes involved in genome stability among yeast species

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On the rate of aneuploidy reversion in a wild yeast model

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Microfluidic platform for monitoring Saccharomyces cerevisiae mutation accumulation

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The population genetics of biological noisePreprint

Weinreich, D. M., Sgouros, T., Raynes, Y., Burtsev, H., Chang, E., Rajakumar, S., Bravo, I. G., & Petak, C. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.01.11.632402 · Cited by 4 · see citing works

Transcription as source of genetic heterogeneity in budding yeast

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Identification of different classes of genome instability suppressor genes through analysis of DNA damage response markers

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Risk Factors for Cancer

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A stress response that allows highly mutated eukaryotic cells to survive and proliferatePreprint

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Characteristics of individual cyp51A SNPs and combinations thereof impacting the azole phenotype in TR 34 -mediated resistance genotypes of Aspergillus fumigatus

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The rate of spontaneous mutations in yeast deficient for MutSβ function

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Wanted: A population genetic theory of biological noise regulation

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A model of autowave self-organization as a hierarchy of active media in the biological evolution

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Advanced Technologies and Mechanisms for Yeast Evolutionary Engineering

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Genome Destabilizing Mutator Alleles Drive Specific Mutational Trajectories inSaccharomyces cerevisiae

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A transient burst of mutations occurs during the normal development of yeast coloniesPreprint

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Comprehensive Mutational Landscape of Yeast Mutator Strains Reveals the Genetic Basis of Mutational Signatures in Cancer

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