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Cited by 642Historical Medical Research and TreatmentsMedical History and InnovationsImmune responses and vaccinations

History of vaccination

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Plotkin, Stanley·2014·Proceedings of the National Academy of Sciences
DOI 10.1073/pnas.1400472111PMC PMC4151719
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Abstract

Vaccines have a history that started late in the 18th century. From the late 19th century, vaccines could be developed in the laboratory. However, in the 20th century, it became possible to develop vaccines based on immunologic markers. In the 21st century, molecular biology permits vaccine development that was not possible before.

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Research works printed but not linked: 10

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Authors
Plotkin, S.
Affiliations
University of Pennsylvania (US)
Corresponding author
Plotkin, Stanley
ORCID
Plotkin, Stanley
Venue
Proceedings of the National Academy of Sciences
Publisher
National Academy of Sciences
Published
2014-08-18
Volume
111
Issue
34
Pages
12283-12287
ISSN
  • 0027-8424 (ISSN-L)
  • 1091-6490
DOI
10.1073/pnas.1400472111
PMC
PMC4151719
OpenAlex
W2117549098
Cited by
642
References
78
Citations by year
2026: 50 · 2025: 62 · 2024: 67 · 2023: 81 · 2022: 89 · 2021: 107 · 2020: 62 · 2019: 44 · 2018: 27 · 2017: 21 · 2016: 14 · 2015: 15 · 2014: 3
FWCI
13.82
Type
journal article
Language
en
Open access
Locations
  • Proceedings of the National Academy of Sciences (publishedVersion)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Historical Medical Research and Treatments
  • Social Sciences › Arts and Humanities › History › Medical History and Innovations
  • Life Sciences › Immunology and Microbiology › Immunology › Immune responses and vaccinations
Keywords
history of vaccination, vaccine development, smallpox vaccination, live attenuated vaccine, inactivated vaccine, subunit vaccine, molecular vaccines, immunological markers, 18th century, 19th century, 20th century, 21st century
MeSH terms
Genetic Engineering, Humans, Vaccination, Vaccines, Attenuated, Viral Vaccines, Vaccines, Inactivated, Reassortant Viruses, Cell Culture Techniques, Vaccines, Subunit, History, 18th Century, History, 19th Century, History, 20th Century, History, 21st Century

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