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Conserved transcriptomic profiles underpin monogamy across vertebrates
Abstract
Social monogamy, typically characterized by the formation of a pair bond, increased territorial defense, and often biparental care, has independently evolved multiple times in animals. Despite the independent evolutionary origins of monogamous mating systems, several homologous brain regions and neuropeptides and their receptors have been shown to play a conserved role in regulating social affiliation and parental care, but little is known about the neuromolecular mechanisms underlying monogamy on a genomic scale. Here, we compare neural transcriptomes of reproductive males in monogamous and nonmonogamous species pairs of Peromyscus mice, Microtus voles, parid songbirds, dendrobatid frogs, and Xenotilapia species of cichlid fishes. We find that, while evolutionary divergence time between species or clades did not explain gene expression similarity, characteristics of the mating system correlated with neural gene expression patterns, and neural gene expression varied concordantly across vertebrates when species transition to monogamy. Our study provides evidence of a universal transcriptomic mechanism underlying the evolution of monogamy in vertebrates.
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“Recent behavioral studies have undertaken increasingly comprehensive cross-species comparisons at the transcriptomic level and also have reported the existence of toolkits of genes and gene modules underlying parallel behaviors (9, 38), loosely analogous to developmental toolkits (16).”
From Behavior-related gene regulatory networks: A new level of organization in the brain (2020) · cites this paper as [38]
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Metadata
- Authors
- Young, R. L., Ferkin, M. H., Ockendon-Powell, N. F., Orr, V. N., Phelps, S. M., Pogány, Á., Richards-Zawacki, C. L., Summers, K., Székely, T., Trainor, B. C., Urrutia, A. O., Zachar, G., O’Connell, L. A., & Hofmann, H. A.
- Affiliations
- Department of Integrative Biology, The University of Texas at Austin, Austin, TX 78712;
- Department of Biological Sciences, The University of Memphis, Memphis, TN 38111;
- Life Sciences, University of Bristol, Bristol BS8 1TQ, United Kingdom;
- Department of Psychology, University of California, Davis, CA 95616;
- Department of Ethology, Eötvös Loránd University, Budapest H-1117, Hungary;
- Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260;
- Department of Biology, East Carolina University, Greenville, NC 27858;
- Milner Centre for Evolution, University of Bath, Bath BA2 7AY, United Kingdom;
- Department of Anatomy, Histology, and Embryology, Semmelweis University, Budapest H-1094, Hungary;
- Department of Biology, Stanford University, Stanford, CA 94305
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 2019-01-07
- Volume
- 116
- Issue
- 4
- Pages
- 1331-1336
- ISSN
- 0027-8424
- 1091-6490
- Cited by
- 93
- References
- 47
- Language
- en
- Update notices
- correction (2019-04-29)
- Funders
- National Science Foundation (IOS-1354942, IOS-1501704, IOS-1601734)
- Alfred P. Sloan Foundation (BR-4900)
- HHS | National Institutes of Health (MH85069-S2)
- Hungarian Scientific Research Fund (OTKA K109337)
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