The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.
Localized cerebral blood flow response at submillimeter columnar resolution
Open accessAbstract
Functional magnetic resonance imaging (fMRI) has been widely used for imaging brain functions. However, the extent of the fMRI hemodynamic response around the active sites, at submillimeter resolution, remains poorly understood and controversial. With the use of perfusion-based fMRI, we evaluated the hemodynamic response in the cat visual cortex after orientation-specific stimuli. Activation maps obtained by using cerebral blood flow fMRI measurements were predominantly devoid of large draining vein contamination and reproducible at columnar resolution. Stimulus-specific cerebral blood flow responses were spatially localized to individual cortical columns, and columnar layouts were resolved. The periodic spacing of orientation columnar structures was estimated to be 1.1 ± 0.2 mm ( n = 14 orientations, five animals), consistent with previous findings. The estimated cerebral blood flow response at full width at half-maximum was 470 μm under single-stimulus conditions without differential subtraction. These results suggest that hemodynamic-based fMRI can indeed be used to map individual functional columns if large-vessel contributions can be minimized or eliminated.
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Self-citationMODALITY AND TOPOGRAPHIC PROPERTIES OF SINGLE NEURONS OF CAT'S SOMATIC SENSORY CORTEX
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Time course EPI of human brain function during task activation
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Self-citationRetinotopic organization in human visual cortex and the spatial precision of functional MRI
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Cited by
What we can do and what we cannot do with fMRI
Logothetis, N. K. (2008) · Nature · doi:10.1038/nature06976 · Cited by 3,612
Representational similarity analysis-connecting the branches of systems neuroscience
Kriegeskorte, N. (2008) · Frontiers in Systems Neuroscience · doi:10.3389/neuro.06.004.2008 · Cited by 3,355
Biophysical and Physiological Origins of Blood Oxygenation Level-Dependent fMRI Signals
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Self-citationHigh-field fMRI unveils orientation columns in humans
Yacoub, E., Harel, N., & Uğurbil, K. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0804110105 · Cited by 566
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Metadata
- Authors
- Duong, T. Q., Kim, D.-S., Uğurbil, K., & Kim, S.-G.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2001-08-28
- Volume
- 98
- Issue
- 19
- Pages
- 10904-10909
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2131996077
- Cited by
- 342
- References
- 37
- FWCI
- 16.83
- Type
- journal article
- Language
- en
- Open access
- bronze
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