The Warburg Effect is the result of faster ATP production by glycolysis than respiration

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AI-driven identification of a selective dual function inhibitor blocking HK2 activity and HK2-VDAC1 interaction displaying enhanced anticancer efficacy under hypoxia

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Computer Vision Identifies Recurrent and Nonrecurrent Ductal Carcinoma in Situ Lesions with Special Emphasis on African-American Women

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Validation of Dynamic Deuterium Metabolic Imaging (DMI) for the Measurement of Cerebral Metabolic Rates of Glucose in Rat

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The Role of Glycolysis in Tumorigenesis—The Many Unresolved Issues

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The eIF3a/m6A/ENO1 axis orchestrates glycolytic reprogramming and cell growth in cervical cancer

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Therapeutic potential of regulating microglial Glut1 in modulating brain glucose metabolism and neuroinflammation in postoperative delirium

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NAD-dependent redox control enables endothelial quiescence and vascular stabilization during angiogenesis

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Discovery of a Novel Potent and Orally Efficacious PGK1 Inhibitor C67–47 for the Treatment of Human Pancreatic Cancer

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Mitochondrial dysfunction in intervertebral disc degeneration: Linking oxidative stress, altered cell fate, and Matrix degeneration

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How do energy metabolism disorders and neuroinflammation collectively contribute to the pathogenesis of Alzheimer’s disease?

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Coupling of ATP and PMF in Escherichia coli is determined by growth conditionsPreprint

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Bioinformatics-based identification of glycolysis-related signatures associated with drug resistance and prognosis in lung adenocarcinoma

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Chronic Cadmium Exposures and Hyperglycemia Additively Drive Mitochondrial Dysfunction in Hepatic Cells: Key Implications for MASLD EtiopathogenesisPreprint

Kumar, R., Chinala, A., Chen, L., Desai, S. P., Garcia, M. A., Blossom, S. J., Campen, M. J., & Gullapalli, R. R. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.09.13.676023

Characteristics of the immune microenvironment, metabolic microenvironment, and gut microbiota in prostate cancer

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F26BP enables control of glycolysis rate independent of energy statePreprint

Kober, M. M., Yang, X., Webb, B. A., & Titov, D. V. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.01.31.703051

Calcium carbonate nanoplatform for remodeling the tumor microenvironment to enhance Chemo-Immunotherapeutic Synergy in breast cancer

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Loss of p27 Kip1 causes metabolic reprogramming and is sufficient to induce a Warburg effect and glutamine addiction in untransformed cellsPreprint

Rolland, L., Mitri, E., Dozier, C., Aguirrebengoa, M., Nemazanyy, I., Joffre, C., Sarry, J., Hatzoglou, A., & Besson, A. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.02.06.703945

TPP-Thiazole Derivatives Ameliorate Psoriasiform Inflammation by Glycolysis Inhibition

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Translational antagonism enables bet-hedging in yeast via mitochondrial bistabilityPreprint

Nanda, P., & Murray, A. W. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.03.30.715437

In-situ generation of hyperbaric hydrogen via crystallization-driven β -MgH 2 reservoirs for cancer-specific starvation therapy

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The Warburg Effect and Aerobic Glycolysis in Tumors

Nehra, B., Suthar, S., Kasnia, R., Demiwal, S., Mondal, M., Sharma, H., & Mojgani, N. (2026) · Cancer treatment and research · doi:10.1007/978-3-032-21861-2_2

The Warburg effect as a metabolic niche construction strategy in the tumor microenvironmentPreprint

Anand, V. A., & Levine, H. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.06.12.731860

Targeting the Warburg Effect in Anaplastic Thyroid Carcinoma: Metabolic Vulnerabilities and Therapeutic Opportunities

Iova, O.-M., Marin, G.-E., Răzniceanu, V., Mocrei-Rebrean, Ș.-M., Pintilie, S. R., Netea-Maier, R. T., & Berindan‐Neagoe, I. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27125472

Evolutionary insights into an ancient fungal transition from land to seaPreprint

Christensen, K. E., Deal, A., & Brem, R. B. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.06.22.733814

Parallel expansion of trehalose transporter genes integrates intestinal energy metabolism with developmental growth in lepidopteran insects

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Hypoxia induces microtubule rearrangement in intestinal epithelial cells

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Ketogenic Diet as an Adjuvant in Epithelial Cancers: Mechanisms, Model Systems, and Translational Opportunities

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Overflow metabolism drives high-rate carbon, nitrogen and phosphorus sequestration in an enriched aerobic microbial community

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Coarse-grained resource allocation modeling for decoding and rewiring microbial metabolism

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The diversity of terminal electron acceptors across eukaryotes

Midha, A. D., & Jain, I. H. (2026) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2026.07.009

Metabolic remodelling in anthracycline cardiotoxicity: mechanisms and therapeutic insights

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Energetic constraints on growth across biological scales

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Metabolic Competition-Driven Antitumor Immunity of glpX -Deficient Engineered Salmonella via Glucose Deprivation and STING Activation in Bladder Cancer

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Disentangling the Crabtree and Warburg effects across syngeneic non-tumor and tumor cellsPreprint

Duraj, T., Miller, E. Y., Ta, N. L., Lee, C., Lee, D. C., Ramos, M. B., Aristizabal‐Henao, J. J., Kiebish, M., Mukherjee, P., Pellicer, M. B., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.10.06.756891

The “Selfish Cell”: The Central Role of Metabolism in Relaying Environmental Stimuli and Controlling Cellular Function

Matteo, S. D., & Gnocchi, D. (2026) · Biology · doi:10.3390/biology15191790

Does specific membrane surface area constrain Escherichia coli energy spillage and therefore aerobic and anaerobic growth rates?Preprint

Putnam, C., Wilken, S. E., Beck, A. E., Beyß, M., Hunt, K., Ebenhöh, O., Nöh, K., & Carlson, R. P. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.10.13.758985

Dynamic flux balance analysis of cancer metabolism using expression-based human cell line modelsPreprint

Kelley, L. P., Dukovski, I., Shah, D., Brézin, L., Korolev, K. S., & Segrè, D. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.10.15.759446

Putting the Warburg effect in reverse

Cracan, V. (2026) · Nature Chemical Biology · doi:10.1038/s41589-026-02343-6

Opportunities and Challenges of Overflow Metabolism in Industrial Microorganisms

Xu, M., Liu, S., Sun, D., & Ren, H. (2026) · ACS Synthetic Biology · doi:10.1021/acssynbio.6c00508

Understanding Cellular Choices in Energy Production

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Mathematical models for explaining the Warburg effect: a review focussed on ATP and biomass production

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