Hypoxia signalling controls metabolic demand

Targeting HIF-1 for cancer therapy

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p53 Regulates Mitochondrial Respiration

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Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH

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Multifaceted roles of glycolytic enzymes

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Succinate dehydrogenase and fumarate hydratase: linking mitochondrial dysfunction and cancer

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Glycolytic Enzymes Can Modulate Cellular Life Span

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The Mammalian Target of Rapamycin (mTOR) Pathway Regulates Mitochondrial Oxygen Consumption and Oxidative Capacity

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Cellular pH regulators: potentially promising molecular targets for cancer chemotherapy

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A HIF1α Regulatory Loop Links Hypoxia and Mitochondrial Signals in Pheochromocytomas

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Lactate: mirror and motor of tumor malignancy

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Akt-dependent transformation: there is more to growth than just surviving

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Reversible Inactivation of HIF-1 Prolyl Hydroxylases Allows Cell Metabolism to Control Basal HIF-1

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The Expanding Family of Eucaryotic Na+/H+Exchangers

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Tumor pH controls the <i>in vivo</i> efficacy of weak acid and base chemotherapeutics

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Signalling hypoxia by HIF hydroxylases

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Investigating hypoxic tumor physiology through gene expression patterns

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The Oxygen Sensor Factor-Inhibiting Hypoxia-Inducible Factor-1 Controls Expression of Distinct Genes through the Bifunctional Transcriptional Character of Hypoxia-Inducible Factor-1α

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Hypoxia Inducible Carbonic Anhydrase IX, Marker of Tumour: Hypoxia, Survival Pathway and Therapy Target

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Failure to prolyl hydroxylate hypoxia‐inducible factor α phenocopies VHL inactivation in vivo

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Lactate dehydrogenase 5 (LDH5) relates to up-regulated hypoxia inducible factor pathway and metastasis in colorectal cancer

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Signalling via the hypoxia-inducible factor-1α requires multiple posttranslational modifications

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The role of p53 in hypoxia-induced apoptosis

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HIF-1 regulates hypoxic induction of NHE1 expression and alkalinization of intracellular pH in pulmonary arterial myocytes

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Ras Inhibition in Glioblastoma Down-regulates Hypoxia-Inducible Factor-1α, Causing Glycolysis Shutdown and Cell Death

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Redox regulation of the hypoxia-inducible factor

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Ras inhibition in glioblastoma down-regulates hypoxia-inducible factor-1alpha, causing glycolysis shutdown and cell death.

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ROS: Really involved in Oxygen Sensing

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The role of carbonic anhydrase IX overexpression in kidney cancer

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Na+/H+ exchangers: physiology and link to hypertension and organ ischemia

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Expression of hypoxia-inducible carbonic anhydrases in brain tumors

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The Hypoxia-Inducible Factor and Tumor Progression Along the Angiogenic Pathway

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Hypoxia-inducible factors, hypoxia, and tumor angiogenesis

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Glucose requirement for hypoxic accumulation of hypoxia-inducible factor-1α (HIF-1α)

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A Mathematical Model of Tissue–Blood Carbon Dioxide Exchange during Hypoxia

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Regulation of HIF: Asparaginyl Hydroxylation

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ARDent about acetylation and deacetylation in hypoxia signalling

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Tumor cell metabolism: cancer's Achilles' heel

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Adipose tissue remodeling and obesity

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Hypoxia, HIF1 and glucose metabolism in the solid tumour

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Targeting mitochondria for cancer therapy

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Regulation of autophagy by cytoplasmic p53

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Tyrosine Phosphorylation Inhibits PKM2 to Promote the Warburg Effect and Tumor Growth

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SIRT3 Opposes Reprogramming of Cancer Cell Metabolism through HIF1α Destabilization

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Hypoxia-Inducible Carbonic Anhydrase IX and XII Promote Tumor Cell Growth by Counteracting Acidosis through the Regulation of the Intracellular pH

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Surface-Charge-Dependent Cell Localization and Cytotoxicity of Cerium Oxide Nanoparticles

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The interplay between MYC and HIF in cancer

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Cancer metabolism and the Warburg effect: the role of HIF-1 and PI3K

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Oxidative stress in prostate cancer

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HIF-Dependent Antitumorigenic Effect of Antioxidants In Vivo

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GLUT1 Expression Is Increased in Hepatocellular Carcinoma and Promotes Tumorigenesis

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Catabolic efficiency of aerobic glycolysis: The Warburg effect revisited

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Administration, distribution, metabolism and elimination of polymer therapeutics

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Mitochondrial gateways to cancer

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Phosphorylation-mediated activation of LDHA promotes cancer cell invasion and tumour metastasis

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Microenvironment and tumor cell plasticity: An easy way out

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Tyrosine Phosphorylation of Lactate Dehydrogenase A Is Important for NADH/NAD + Redox Homeostasis in Cancer Cells

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The mitochondrial voltage-dependent anion channel 1 in tumor cells

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Heterogeneity in Cancer Metabolism: New Concepts in an Old Field

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The Warburg effect: Evolving interpretations of an established concept

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MUC1 mucin stabilizes and activates hypoxia-inducible factor 1 alpha to regulate metabolism in pancreatic cancer

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Chapter 1 Physiological Roles of Ribosomal Protein S6: One of Its Kind

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Modulation of Apoptosis by Natural Products for Cancer Therapy

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Metabolic Reprogramming by the PI3K-Akt-mTOR Pathway in Cancer

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Hypoxic Reactive Oxygen Species Regulate the Integrated Stress Response and Cell Survival

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GLUT1 as a therapeutic target in hepatocellular carcinoma

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Glycogen Synthesis is Induced in Hypoxia by the Hypoxia-Inducible Factor and Promotes Cancer Cell Survival

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PDK-1 regulates lactate production in hypoxia and is associated with poor prognosis in head and neck squamous cancer

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VDAC1: from structure to cancer therapy

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Bone Marrow Adipocytes Facilitate Fatty Acid Oxidation Activating AMPK and a Transcriptional Network Supporting Survival of Acute Monocytic Leukemia Cells

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Hypoxia and hypoxia inducible factors in tumor metabolism

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Hypoxia Prolongs Monocyte/Macrophage Survival and Enhanced Glycolysis Is Associated with Their Maturation under Aerobic Conditions

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