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BEHAVIORAL MUTANTS OF Drosophila ISOLATED BY COUNTERCURRENT DISTRIBUTION

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Benzer, Seymour·1967·Proceedings of the National Academy of Sciences

Abstract

Complex as it is, much of the vast network of cellular functions has been successfully dissected, on a microscopic scale, by the use of mutants in which one element is altered at a time. A similar approach may be fruitful in tackling the complex structures and events underlying behavior, using behavioral mutations to indicate modifications of the nervous system. Drosophila offers the same advantages to such a study as it did to classical genetics, namely, large numbers and short generation time, to which may now be added an enormous store of accumulated knowledge concerning the organism. Containing about 105 neurons, the fly's nervous system is roughly halfway, on a logarithmic scale, between a single neuron and the human brain, and the fly is possessed of a rich repertoire of behavior. The considerable literature on Drosophila behavior since Carpenter's 1905 paper [1] has recently been reviewed by Manning.[2]

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Metadata

Authors
Benzer, S.
Venue
Proceedings of the National Academy of Sciences
Published
1967-09
Volume
58
Issue
3
Pages
1112-1119
ISSN
  • 0027-8424 (ISSN-L)
  • 1091-6490
OpenAlex
W2032972160
Cited by
672
References
0
FWCI
3.04
Type
journal article
Language
en
Open access
green

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