The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.
Dietary pesticides (99.99% all natural).
Open accessAbstract
The toxicological significance of exposures to synthetic chemicals is examined in the context of exposures to naturally occurring chemicals. We calculate that 99.99% (by weight) of the pesticides in the American diet are chemicals that plants produce to defend themselves. Only 52 natural pesticides have been tested in high-dose animal cancer tests, and about half (27) are rodent carcinogens; these 27 are shown to be present in many common foods. We conclude that natural and synthetic chemicals are equally likely to be positive in animal cancer tests. We also conclude that at the low doses of most human exposures the comparative hazards of synthetic pesticide residues are insignificant.
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Citations
Cites
Dietary Carcinogens and Anticarcinogens: Oxygen radicals and degenerative diseases
Ames, B. N. (1983) · Science · doi:10.1126/science.6351251 · Cited by 2,969
Self-citationHerbivores: Their interaction with secondary plant metabolites
Chapman, R. F. (1980) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(80)90169-3 · Cited by 1,431
Glucosinolates and their breakdown products in food and food plants
Fenwick, G. R., Heaney, R. K., Mullin, W. J., & VanEtten, C. H. (1983) · C R C Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398209527361 · Cited by 1,320
Shepard, T. H. (1981) · Teratology · doi:10.1002/tera.1420230118 · Cited by 1,296
Ranking Possible Carcinogenic Hazards
Ames, B. N., Magaw, R., & Gold, L. S. (1987) · Science · doi:10.1126/science.3563506 · Cited by 557
Self-citationA carcinogenic potency database of the standardized results of animal bioassays
Gold, L. S., Sawyer, C. B., Magaw, R., Backman, G. M., De Veciana, M., Levinson, R., Hooper, N. K., Havender, W. R., Bernstein, L., Peto, R., et al. (1984) · Environmental Health Perspectives · doi:10.1289/ehp.84589 · Cited by 501
Self-citationChemical carcinogenesis: too many rodent carcinogens.
Ames, B. N., & Gold, L. S. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.19.7772 · Cited by 489
Self-citationMiller, E. C., Swanson, A. B., Phillips, D. H., Fletcher, T. L., Liem, A., & MILLER, J. A. (1983) · PubMed · Cited by 421
Ishidate, M., Harnois, M. C., & Sofuni, T. (1988) · Mutation Research/Reviews in Genetic Toxicology · doi:10.1016/0165-1110(88)90023-1 · Cited by 328
Responses of the L5178Y tk+/tk− mouse lymphoma cell forward mutation assay ii: 18 coded chemicals
McGregor, D. B., Brown, A., Cattanach, P., Edwards, I., McBride, D., & Caspary, W. J. (1988) · Environmental and Molecular Mutagenesis · doi:10.1002/em.2850110110 · Cited by 318
Cited by
Oxidants, antioxidants, and the degenerative diseases of aging.
Ames, B. N., Shigenaga, M. K., & Hagen, T. M. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.17.7915 · Cited by 5,958
Self-citationMechanisms of DNA damage, repair, and mutagenesis
Chatterjee, N., & Walker, G. C. (2017) · Environmental and Molecular Mutagenesis · doi:10.1002/em.22087 · Cited by 2,039
“Natural toxins constitute a class of genotoxic and carcinogenic compounds, which are normally used by microorganisms or fungi in defense responses [Ames et al., 1990].”
Bitter taste, phytonutrients, and the consumer: a review
Drewnowski, A., & Gomez-Carneros, C. (2000) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/72.6.1424 · Cited by 1,353
Harman, D. (1992) · Mutation Research/DNAging · doi:10.1016/0921-8734(92)90030-s · Cited by 902
Too Many Rodent Carcinogens: Mitogenesis Increases Mutagenesis
Ames, B. N., & Gold, L. S. (1990) · Science · doi:10.1126/science.2136249 · Cited by 770
Self-citation
Metadata
- Authors
- Ames, B. N., Profet, M., & Gold, L. S.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1990-10
- Volume
- 87
- Issue
- 19
- Pages
- 7777-7781
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W1971128999
- Cited by
- 395
- References
- 36
- FWCI
- 49.09
- Type
- journal article
- Language
- en
- Open access
- green
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- Ames, B. N., Profet, M., & Gold, L. S. (1990). Dietary pesticides (99.99% all natural). Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.87.19.7777
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
