Unique Lipoproteins Secreted by Primary Astrocytes From Wild Type, apoE (−/−), and Human apoE Transgenic Mice

Cited by (223)

Items 101–200 of 223

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  2. Effects of Age on Gene Expression during Estrogen-Induced Synaptic Sprouting in the Female Rat
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  3. Murine synaptosomal lipid raft protein and lipid composition are altered by expression of human apoE 3 and 4 and by increasing age
    Igbavboa, U., Eckert, G.P., Malo, T.M., Studniski, A.E., Johnson, L.N.A., Yamamoto, N., Kobayashi, M., Fujita, S.C., Appel, T.R., Müller, W.E. et al. · 2005 · Journal of the Neurological Sciences
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    Astrid Weiler, Anne Volkenhoff, Helen Hertenstein, Stefanie Schirmeier · 2017 · Neurobiology of Disease
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    Gao, Yi, Ye, Shiying, Tang, Yuehong, Tong, Wenjuan, Sun, Shaowei · 2023 · Neurochemistry International
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  7. Astrocytes and the Warning Signs of Intracerebral Hemorrhagic Stroke
    Annalisa Scimemi · 2018 · Neural Plasticity
  8. A role for lipoprotein lipase during synaptic remodeling in the adult mouse brain
    Jean‐François Blain, Eric Paradis, Sophie B. Gaudreault, Danielle L. Champagne, Denis Richard, Judes Poirier · 2004 · Neurobiology of Disease
  9. α-Synuclein Regulates Neuronal Cholesterol Efflux
    Jen-Hsiang T. Hsiao, Glenda Margaret Halliday, Woojin Kim · 2017 · Molecules
  10. A polymorphism in lipoprotein lipase affects the severity of Alzheimer's disease pathophysiology
    Jean‐François Blain, Nicole Aumont, Louise Théroux, Doris Dea, Judes Poirier · 2006 · European Journal of Neuroscience
  11. In situ AFM studies of astrocyte-secreted apolipoprotein E- and J-containing lipoproteins
    Justin A. Legleiter, Ronald Bradley Demattos, David M. Holtzman, Tomasz Kowalewski · 2004 · Journal of Colloid and Interface Science
  12. Apolipoprotein E LDL receptor-binding domain-containing high-density lipoprotein: A nanovehicle to transport curcumin, an antioxidant and anti-amyloid bioflavonoid
    Panupon Khumsupan, Ricardo Ramírez, Darin Khumsupan, Vasanthy Narayanaswami · 2010 · Biochimica et Biophysica Acta (BBA) - Biomembranes
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    Monique T Mulder · 2009 · Current Opinion in Clinical Nutrition & Metabolic Care
  14. Lipid efflux mechanisms, relation to disease and potential therapeutic aspects
    David Castaño, Chutima Rattanasopa, Vera Filipa Monteiro-Cardoso, Maria Corlianò, Yiran Liu, A. Zhong, Mihaela Rusu, Elisa Anamaria Liehn, Roshni Rebecca Singaraja · 2020 · Advanced Drug Delivery Reviews
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  16. Apolipoprotein E acts to increase nitric oxide production in macrophages by stimulating arginine transport
    Carol A. Colton, Meggan Czapiga, Julie C. Snell, Olga N. Chernyshev, Michael Peter Vitek · 2001 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  17. The tocopherol transfer protein mediates vitamin E trafficking between cerebellar astrocytes and neurons
    Lynn M. Ulatowski, Mikel D. Ghelfi, Ryan West, J. Atkinson, Carrie J. Finno, Danny Manor · 2022 · Journal of Biological Chemistry
  18. Absence of ApoE Upregulates Murine Brain ApoD and ABCA1 Levels, But Does Not Affect Brain Sterol Levels, While Human ApoE3 and Human ApoE4 Upregulate Brain Cholesterol Precursor Levels
    Paula J. Jansen, Dieter Lütjohann, Karin Thelen, Klaus von Bergmann, Fred VAN LEUVEN, Frans C. S. Ramaekers, Monique Monique · 2009 · Journal of Alzheimer s Disease
  19. Understanding the Exchange of Systemic HDL Particles Into the Brain and Vascular Cells Has Diagnostic and Therapeutic Implications for Neurodegenerative Diseases
    Juno S. Van Valkenburgh, Cristiana Joy Meuret, Ashley E. Martinez, Vibha Kodancha, Victoria A. Solomon, Kai Chen, Hussein N. Yassine · 2021 · Frontiers in Physiology
  20. Expression of sterol 27-hydroxylase in glial cells and its regulation by liver X receptor signaling
    Federica Gilardi, Barbara Viviani, Andrea Galmozzi, Mariaserena Boraso, Stefano Bartesaghi, A Torri, Donatella Caruso, Maurizio Crestani, Marina Marinovich, Emma De Fabiani · 2009 · Neuroscience
  21. Self-Assembly of HEK Cell-Secreted ApoE Particles Resembles ApoE Enrichment of Lipoproteins as a Ligand for the LDL Receptor-Related Protein
    LaDu, Mary Jo, Stine,, W. Blaine, Narita, Masaaki, Getz, Godfrey S., Reardon, Catherine A., Bu, Guojun · 2006 · Biochemistry
  22. Cerebrospinal Fluid Particles in Alzheimer Disease and Parkinson Disease
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  23. Apolipoprotein E secreted by astrocytes forms antiparallel dimers in discoidal lipoproteins
    Strickland, Michael R., Rau, Michael J., Summers, Brock, Basore, Katherine, Wulf, John, Jiang, Hong, Chen, Yun, Ulrich, Jason D., Randolph, Gwendalyn J., Zhang, Rui et al. · 2024 · Neuron
  24. Advancements in APOE and dementia research: Highlights from the 2023 AAIC Advancements: APOE conference
    Kloske, Courtney M., Belloy, Michael E., Blue, Elizabeth E., Bowman, Gregory R., Carrillo, Maria C., Chen, Xiaoying, Chiba‐Falek, Ornit, Davis, Albert A., Paolo, Gilbert Di, Garretti, Francesca et al. · 2024 · Alzheimer's & Dementia
  25. Optimized Negative Staining: a High-throughput Protocol for Examining Small and Asymmetric Protein Structure by Electron Microscopy
    Matthew J. Rames, Yadong Yu, Gang Ren · 2014 · Journal of Visualized Experiments
  26. Astrocytes produce and secrete FGF-1, which promotes the production of apoE-HDL in a manner of autocrine action
    Jin‐ichi Ito, Yuko Nagayasu, Rui Lu, Alireza Kheirollah, Michi Hayashi, Shinji Yokoyama · 2005 · Journal of Lipid Research
  27. Preferential interactions between ApoE-containing lipoproteins and Aβ revealed by a detection method that combines size exclusion chromatography with non-reducing gel-shift
    LaDu, Mary Jo, Munson, Gregory W., Jungbauer, Lisa, Getz, Godfrey S., Reardon, Catherine A., Tai, Leon M., Yu, Chunjiang · 2012 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
  28. Regulation of hippocampal cholesterol metabolism by apoE and environmental stimulation
    Levi, Ofir, Lütjohann, Dieter, Devir, Aliza, Von Bergmann, Klaus, Hartmann, Tobias, Michaelson, Daniel M. · 2005 · Journal of Neurochemistry
  29. APOE ε4 and lipid levels affect risk of recurrent nonlobar intracerebral hemorrhage
    Miriam R. Raffeld, Alessandro Biffi, Thomas W.K. Battey, Alison M. Ayres, Anand Viswanathan, Steven Mark Greenberg, Jonathan M. Rosand, Christopher D. Anderson · 2015 · Neurology
  30. Differential effects of apoE4 and activation of ABCA1 on brain and plasma lipoproteins
    Boehm-Cagan, Anat, Bar, Roni, Harats, Dror, Shaish, Aviv, Levkovitz, Hana, Bielicki, John K., Johansson, Jan O., Michaelson, Daniel M. · 2016 · PLOS ONE
  31. The Modulating Effect of Mechanical Changes in Lipid Bilayers Caused by ApoE-Containing Lipoproteins on Aβ Induced Membrane Disruption
    Justin A. Legleiter, John Denis Fryer, David M. Holtzman, Tomasz Kowalewski · 2011 · ACS Chemical Neuroscience
  32. A Novel Perspective on the ApoM-S1P Axis, Highlighting the Metabolism of ApoM and Its Role in Liver Fibrosis and Neuroinflammation
    Stefan Hajny, Christina Christoffersen · 2017 · International Journal of Molecular Sciences
  33. The influence of APOEε4 on the pTau interactome in sporadic Alzheimer’s disease
    Manon Thierry, Jackeline Ponce, Mitchell Martá-Ariza, Manor Askenazi, Arline Faustin, Dominique Leitner, Geoffrey Pires, Evgeny Kanshin, Eleanor Drummond, Beatrix M. Ueberheide et al. · 2024 · Acta Neuropathologica
  34. An acidic fibroblast growth factor-like factor secreted into the brain cell culture medium upregulates apoE synthesis, HDL secretion and cholesterol metabolism in rat astrocytes
    Sachiko Ueno, Jin‐ichi Ito, Yuko Nagayasu, Toshi A. Furukawa, Shinji Yokoyama · 2002 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  35. Neurological aspects of SARS-CoV-2 infection: lipoproteins and exosomes as Trojan horses
    Sin Man Lam, Xun Huang, Guanghou Shui · 2022 · Trends in Endocrinology and Metabolism
  36. Cerebrospinal fluid-induced retardation of amyloid β aggregation correlates with Alzheimer's disease and the APOE ε4 allele
    Eden Rebecca Padayachee, Henrik Zetterberg, Erik Portelius, Jan Borén, José Luís Molinuevo, Nancy C. Andreasen, Risto Cukalevski, Sara Snogerup Linse, Kaj Blennow, Ulf Andréasson · 2016 · Brain Research
  37. High-density lipoprotein-related cholesterol metabolism in Alzheimer's disease
    Pedrini, Steve, Chatterjee, Pratishtha, Hone, Eugene, Martins, Ralph N. · 2021 · Journal of Neurochemistry
  38. Identification of a Chrysanthemic Ester as an Apolipoprotein E Inducer in Astrocytes
    Jianjia Fan, Shahab Zareyan, Wenchen Zhao, Yoko Shimizu, Tom A. Pfeifer, Jun‐Hyung Tak, Murray B. Isman, Bernard G. Van den Hoven, Mark E. Duggan, Michael W. Wood et al. · 2016 · PLoS ONE
  39. Protective ApoE variants support neuronal function by effluxing oxidized phospholipids
    Ralhan, Isha, Do, Alison D., Bae, Ju-Young, Feringa, Femke M., Cai, Wendy, Chang, Jinlan, Chik, Kennedi, Lee, Nathanael Y.J., Gerry, Christopher J., van der Kant, Rik et al. · 2026 · Neuron
  40. The cholesteryl ester transfer protein (CETP) raises cholesterol levels in the brain
    Felix Oestereich, Noosha Yousefpour, Ethan Yang, Jasmine Phénix, Zari Saadati Nezhad, Albert Nitu, Antonio Vázquez Cobá, Alfredo Ribeiro‐da‐Silva, Pierre Chaurand, Lisa Marie Munter · 2022 · Journal of Lipid Research
  41. Fatty acid sensing in the brain: The role of glial-neuronal metabolic crosstalk and horizontal lipid flux
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  42. ApoE and cholesterol in schizophrenia and bipolar disorder: comparison of grey and white matter and relation with APOE genotype
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  43. An ABCA1-independent pathway for recycling a poorly lipidated 8.1 nm apolipoprotein E particle from glia
    Fan, Jianjia, Stukas, Sophie, Wong, Charmaine, Chan, Jennifer, May, Sharon, DeValle, Nicole, Hirsch-Reinshagen, Veronica, Wilkinson, Anna, Oda, Michael N., Wellington, Cheryl L. · 2011 · Journal of Lipid Research
  44. Inhibition of ACAT as a Therapeutic Target for Alzheimer's Disease Is Independent of ApoE4 Lipidation
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  45. Circadian Regulation of Apolipoproteins in the Brain: Implications in Lipid Metabolism and Disease
    C. Lee, Charlotte Ellzabeth Murrell, Alexander Chu, Xiaoyue Pan · 2023 · International Journal of Molecular Sciences
  46. Apolipoprotein Aβ: Black Sheep in a Good Family
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  47. Apolipoprotein A-I induces translocation of protein kinase Cα to a cytosolic lipid-protein particle in astrocytes
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  48. Lipoproteins produced by ApoE–/– astrocytes infected with adenovirus expressing human ApoE
    Dacheng Peng, Ching Song, Catherine A. Reardon, Shutsung Liao, Godfrey S. Getz · 2003 · Journal of Neurochemistry
  49. Current insights into apolipoprotein E and the immune response in Alzheimer's disease
    Lin, Peter Bor‐Chian, Holtzman, David M. · 2024 · Immunological Reviews
  50. Stage-Specific Association of Apolipoprotein A-I and E in Developing Mouse Retina
    真吾 車田, Akishi Onishi, Hiroo Imai, Kumiko Ishii, Toshihide Kobayashi, Satoshi B. Sato · 2007 · Investigative Ophthalmology & Visual Science
  51. Study of Exosomes Shed New Light on Physiology of Amyloidogenesis
    Guillaume van Niel · 2016 · Cellular and Molecular Neurobiology
  52. Rosuvastatin reduces microglia in the brain of wild type and ApoE knockout mice on a high cholesterol diet; Implications for prevention of stroke and AD
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  53. APOE Lipoprotein Particles: Pathophysiology, Therapy, and the Crosstalk in Alzheimer’s Disease and Cardiovascular Disease
    Чан Лю, Juan Liu, Yanyang Wang, Shang-Fu Xu, Li-Mei Yu · 2025 · Molecular Neurobiology
  54. A novel apoE-mimetic increases brain apoE levels, reduces Aβ pathology and improves memory when treated before onset of pathology in male mice that express APOE3
    Ana Carolina Valencia‐Olvera, Deebika Balu, Shreya Bellur, Thomas P. McNally, Yaseen Saleh, Don Pham, Shivesh Ghura, Jason M. York, Jan O. Johansson, Mary Jo LaDu et al. · 2023 · Alzheimer s Research & Therapy
  55. Arabidopsis thaliana extracts optimized for polyphenols production as potential therapeutics for the APOE-modulated neuroinflammation characteristic of Alzheimer’s disease in vitro
    Shivesh Ghura, Leon M. Tai, Ming Zhao, Nicole Collins, Chun‐Tao Che, Katherine M. Warpeha, Mary Jo LaDu · 2016 · Scientific Reports
  56. HDL and Endothelial Function
    Yufei Wu, Yangkai Xu, Jie Chen, Mingming Zhao, Kerry‐Anne Rye · 2022 · Advances in experimental medicine and biology
  57. Apolipoprotein E polymorphism and the risk of intracranial aneurysms in a Chinese population
    Hao Liu, Ping Mao, Changhou Xie, Wanfu Xie, Maode Wang, Haitao Jiang · 2016 · BMC Neurology
  58. Roles of glia cells in cholesterol homeostasis in the brain
    Jin‐ichi Ito, Shinji Yokoyama · 2003 · Advances in molecular and cell biology
  59. Role of A β Transport and Clearance in the Pathogenesis and Treatment of Alzheimer’s Disease
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  60. Neuroimmunometabolism: how metabolism orchestrates immune response in healthy and diseased brain
    Anil Kumar Rana, Babita Bhatt, Chitralekha Gusain, Suryanarayan Biswal, Debashree Das, Mohit Kumar · 2025 · American Journal of Physiology-Endocrinology and Metabolism
  61. Apolipoprotein E Gene Polymorphism and the Risk of Intracerebral Hemorrhage in the Chinese Population
    Rongjun Zhang, Xiaofeng Wang, Jianxin Liu, Shuzhen Yang, Zongchun Tang, LI Shuan-de, Yabin Peng, Hongbin Zhang, Xingkui Yang, Yongchun Zhou et al. · 2011 · Genetic Testing and Molecular Biomarkers
  62. Lipolysis-Stimulated Lipoprotein Receptor Acts as Sensor to Regulate ApoE Release in Astrocytes
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  63. Nitric oxide counteracts the hyperoxia-induced proliferation and proinflammatory responses of mouse astrocytes
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  64. Bioactive TGF‐β can associate with lipoproteins and is enriched in those containing apolipoprotein E3
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  65. Could Lipoprotein Lipase Play a Role in Alzheimer's Disease?
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  67. Targeted Suppression of Lipoprotein Receptor LSR in Astrocytes Leads to Olfactory and Memory Deficits in Mice
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  68. Lipid peroxidation and Alzheimer’s disease: Key role of Amyloid-β
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  69. LCAT deficiency does not impair amyloid metabolism in APP/PS1 mice
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  70. Lipidome and proteome of astrocyte and microglia ApoE lipoprotein reveal differences based on cell type and ApoE isoform
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  71. Lipid Metabolism and Oxidation in Neurons and Glial Cells
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  72. ApoE Isoforms Inhibit Amyloid Aggregation of Proinflammatory Protein S100A9
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  78. ApoE isoform-specific differences in behavior and cognition associated with subchronic MPTP exposure
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  79. Protective ApoE variants support neuronal function by extracting peroxidated lipids
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  83. No association between ApoE polymorphism and febrile seizures
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  84. Distribution of apolipoprotein E allele frequencies of the Han Chinese in an iodine-deficient mountainous area
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  88. Cholesterol Trafficking in the Brain
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  89. Inflammation in Alzheimer's Disease: Cross-talk between Lipids and Innate Immune Cells of the Brain
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  99. Modulating Amyloid Beta Clearance by Altering Cellular and Whole Brain Apolipoprotein E Metabolism
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