Mechanism of Human SIRT1 Activation by Resveratrol

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5. Resveratrol in prevention and treatment of common clinical conditions of aging.
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6. Resveratrol, sirtuins, and the promise of a DR mimetic
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9. Resveratrol as a calorie restriction mimetic: therapeutic implications
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12. Biosynthesis of plant-specific stilbene polyketides in metabolically engineered Escherichia coli
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18. Kinetic and Structural Basis for Acyl-Group Selectivity and NAD+ Dependence in Sirtuin-Catalyzed Deacylation
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20. Resveratrol enhances p53 acetylation and apoptosis in prostate cancer by inhibiting MTA1/NuRD complex
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21. Dietary HDAC inhibitors: time to rethink weak ligands in cancer chemoprevention?
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22. Dietary oxyresveratrol prevents parkinsonian mimetic 6-hydroxydopamine neurotoxicity
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24. Resveratrol and Neurodegenerative Diseases: Activation of SIRT1 as the Potential Pathway towards Neuroprotection
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26. Sirtuins and Disease: The Road Ahead
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27. Resveratrol protects cardiomyocytes from hypoxia-induced apoptosis through the SIRT1–FoxO1 pathway
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28. Resveratrol improves learning and memory in normally aged mice through microRNA-CREB pathway
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30. Resveratrol and novel potent activators of SIRT1: effects on aging and age-related diseases
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31. Pleiotropic mechanisms facilitated by resveratrol and its metabolites
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32. The journey of resveratrol from yeast to human
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33. The Role of Mammalian Sirtuins in the Regulation of Metabolism, Aging, and Longevity
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34. Resveratrol neuroprotection in stroke and traumatic CNS injury
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41. Calorie restriction and resveratrol in cardiovascular health and disease
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42. SIRT1 as a potential therapeutic target for treatment of nonalcoholic fatty liver disease
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43. Resveratrol Potentiates Glucose-stimulated Insulin Secretion in INS-1E β-Cells and Human Islets through a SIRT1-dependent Mechanism
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44. Resveratrol and Endothelial Nitric Oxide
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45. Resveratrol attenuates steatosis in obese Zucker rats by decreasing fatty acid availability and reducing oxidative stress
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46. Neuronal Sirt3 Protects against Excitotoxic Injury in Mouse Cortical Neuron Culture
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47. Concurrent regulation of AMP-activated protein kinase and SIRT1 in mammalian cells
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48. Resveratrol and Ophthalmic Diseases
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49. Senescence and senotherapeutics: a new field in cancer therapy
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50. Lipid Droplet-Derived Monounsaturated Fatty Acids Traffic via PLIN5 to Allosterically Activate SIRT1
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51. NAD+metabolism and oxidative stress: the golden nucleotide on a crown of thorns
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52. Novel Role of the SIRT1 in Endocrine and Metabolic Diseases
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54. Resveratrol and life extension
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55. Resveratrol as a Natural Autophagy Regulator for Prevention and Treatment of Alzheimer’s Disease
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56. Role of SIRT1 and FOXO factors in eNOS transcriptional activation by resveratrol
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57. Epigenetic linkage of aging, cancer and nutrition
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58. Resveratrol is a class IA phosphoinositide 3-kinase inhibitor
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59. Resveratrol Induces Brain Resilience Against Alzheimer Neurodegeneration Through Proteostasis Enhancement
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60. Significance of wine and resveratrol in cardiovascular disease: French paradox revisited.
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61. The controversial world of sirtuins
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62. Aging by epigenetics—A consequence of chromatin damage?
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63. Resveratrol Derivatives as Potential Treatments for Alzheimer’s and Parkinson’s Disease
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64. Adenosine Mimetics as Inhibitors of NAD+-Dependent Histone Deacetylases, from Kinase to Sirtuin Inhibition
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65. Resveratrol and chemoprevention
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68. Sirtuin 1 (SIRT1): The Misunderstood HDAC
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71. Synthesis and Evaluation of Substituted Chroman-4-one and Chromone Derivatives as Sirtuin 2-Selective Inhibitors
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73. Janus‐faced role of SIRT1 in tumorigenesis
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74. Calorie Restriction and Dietary Restriction Mimetics: A Strategy for Improving Healthy Aging and Longevity
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75. Differential expression of sirtuins in the aging rat brain
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76. Biochemical effects of SIRT1 activators
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77. Mechanism-Based Inhibition of Sir2 Deacetylases by Thioacetyl-Lysine Peptide
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78. Anti-inflammatory effect of resveratrol on TNF-α-induced MCP-1 expression in adipocytes
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79. Prevention and treatment of diabetes with resveratrol in a non-obese mouse model of type 1 diabetes
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81. A continuous microplate assay for sirtuins and nicotinamide-producing enzymes
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85. Perspectives on translational and therapeutic aspects of SIRT1 in inflammaging and senescence
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86. Sirtuin activators
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88. SirT1-null mice develop tumors at normal rates but are poorly protected by resveratrol
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89. Host sirtuin 1 regulates mycobacterial immunopathogenesis and represents a therapeutic target against tuberculosis
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98. Polyphenols: Planting the seeds of treatment for the metabolic syndrome
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99. Epigenetic effects of natural polyphenols: A focus on SIRT1‐mediated mechanisms
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