Structural Basis for Sorting Mechanism of p62 in Selective Autophagy

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2. The Selective Autophagy Receptor p62 Forms a Flexible Filamentous Helical Scaffold
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3. iLIR
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4. LUBAC-synthesized linear ubiquitin chains restrict cytosol-invading bacteria by activating autophagy and NF-κB
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5. Molecular cross-talk between the NRF2/KEAP1 signaling pathway, autophagy, and apoptosis
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6. Activation and targeting of ATG8 protein lipidation
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7. Oxidative Stress in Placenta: Health and Diseases
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8. Accumulation of p62/ SQSTM 1 is associated with poor prognosis in patients with lung adenocarcinoma
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9. LC3 Binding to the Scaffolding Protein JIP1 Regulates Processive Dynein-Driven Transport of Autophagosomes
   Meng-meng Fu, Jeffrey J. Nirschl, E. Holzbaur · 2014 · Developmental Cell
10. Regulation of Amyloid Precursor Protein Processing by the Beclin 1 Complex
    Philipp A. Jaeger, Fiona Pickford, Chung-Huan Johnny Sun, Kurt M. Lucin, Eliezer Masliah, Tony Wyss‐Coray · 2010 · PLoS ONE
11. The mechanisms of graphene-based materials-induced programmed cell death: a review of apoptosis, autophagy, and programmed necrosis
    Lingling Ou, Shaoqiang Lin, Bin Song, Jia Liu, Renfa Lai, Longquan Shao · 2017 · International Journal of Nanomedicine
12. Autophagy is involved in traumatic brain injury-induced cell death and contributes to functional outcome deficits in mice
    Cheng‐Liang Luo, B.-X. Li, Q.-Q. Li, X.-P. Chen, Yaxuan Sun, H. Bao, Ding-Kun Dai, Yiwen Shen, Hongfei Xu, H. Ni et al. · 2011 · Neuroscience
13. Autophagy regulates lipid metabolism through selective turnover of NCoR1
    Saito, Tetsuya, Kuma, Akiko, Sugiura, Yuki, Ichimura, Yoshinobu, Obata, Miki, Kitamura, Hiroshi, Okuda, Shujiro, Lee, Hyeon-Cheol, Ikeda, Kazutaka, Kanegae, Yumi et al. · 2019 · Nature Communications
14. Atomistic Autophagy: The Structures of Cellular Self-Digestion
    James H. Hurley, Brenda Arlene Schulman · 2014 · Cell
15. Autophagy and ALS: mechanistic insights and therapeutic implications
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16. Oxidation of SQSTM1/p62 mediates the link between redox state and protein homeostasis
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17. The Keap1–Nrf2 system as an in vivo sensor for electrophiles
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18. iLIR database: A web resource for LIR motif-containing proteins in eukaryotes
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19. Beclin 1-independent autophagy contributes to apoptosis in cortical neurons
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20. Substrate recognition in selective autophagy and the ubiquitin–proteasome system
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21. p62 at the Interface of Autophagy, Oxidative Stress Signaling, and Cancer
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22. All-you-can-eat: autophagy in neurodegeneration and neuroprotection
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23. The cellular pathways of neuronal autophagy and their implication in neurodegenerative diseases
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24. OATL1, a novel autophagosome-resident Rab33B-GAP, regulates autophagosomal maturation
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25. Functions of Autophagy in Hepatic and Pancreatic Physiology and Disease
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26. DNA Damage Response and Autophagy: A Meaningful Partnership
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27. Regulation of the Keap1–Nrf2 pathway by p62/SQSTM1
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28. Molecular determinants regulating selective binding of autophagy adapters and receptors to ATG8 proteins
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29. Interaction Domains of p62: A Bridge Between p62 and Selective Autophagy
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30. Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate selection
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31. The Diversity of Ubiquitin Recognition: Hot Spots and Varied Specificity
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32. MBSJ MCC Young Scientist Award 2009 REVIEW: Selective autophagy regulates various cellular functions
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33. Structural insights into the recognition of phosphorylated FUNDC1 by LC3B in mitophagy
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34. IRE1 plays an essential role in ER stress-mediated aggregation of mutant huntingtin via the inhibition of autophagy flux
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35. The elimination of accumulated and aggregated proteins: A role for aggrephagy in neurodegeneration
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36. Defective recognition of LC3B by mutant SQSTM1/p62 implicates impairment of autophagy as a pathogenic mechanism in ALS-FTLD
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37. Autophagy: More Than a Nonselective Pathway
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38. SQSTM1 mutations – Bridging Paget disease of bone and ALS/FTLD
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39. Characterization of macroautophagic flux in vivo using a leupeptin-based assay
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40. Dual Role of Autophagy in Stress‐Induced Cell Death in Rheumatoid Arthritis Synovial Fibroblasts
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41. Structure-Based Reassessment of the Caveolin Signaling Model: Do Caveolae Regulate Signaling through Caveolin-Protein Interactions?
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42. TP53INP1, a tumor suppressor, interacts with LC3 and ATG8-family proteins through the LC3-interacting region (LIR) and promotes autophagy-dependent cell death
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43. Autophagy-related Protein 32 Acts as Autophagic Degron and Directly Initiates Mitophagy
    Noriko Kondo‐Okamoto, Nobuo N. Noda, Sho W. Suzuki, Hitoshi Nakatogawa, Ikuko Takahashi, Miou Matsunami, Ayako Hashimoto, Fuyuhiko Inagaki, Yoshinori Ohsumi, Koji Okamoto · 2012 · Journal of Biological Chemistry
44. History of the Selective Autophagy Research: How Did It Begin and Where Does It Stand Today?
    Vladimir Kirkin · 2019 · Journal of Molecular Biology
45. Crystal Structure of the Ubiquitin-associated (UBA) Domain of p62 and Its Interaction with Ubiquitin
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46. Inclusion body myopathy, Paget's disease of the bone and fronto-temporal dementia: a disorder of autophagy
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47. p62-mediated phase separation at the intersection of the ubiquitin-proteasome system and autophagy
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48. Histone deacetylases 1 and 2 regulate autophagy flux and skeletal muscle homeostasis in mice
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49. The autophagy receptor p62/SQST-1 promotes proteostasis and longevity in C. elegans by inducing autophagy
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50. HSP70 Inhibition by the Small-Molecule 2-Phenylethynesulfonamide Impairs Protein Clearance Pathways in Tumor Cells
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51. Role of p62/SQSTM1 in liver physiology and pathogenesis
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52. Autophagy in health and disease. 3. Involvement of autophagy in muscle atrophy
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53. Emerging role of p62/sequestosome-1 in the pathogenesis of Alzheimer's disease
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54. FYCO1 Contains a C-terminally Extended, LC3A/B-preferring LC3-interacting Region (LIR) Motif Required for Efficient Maturation of Autophagosomes during Basal Autophagy
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55. The role of ALFY in selective autophagy
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56. Mitophagy-driven metabolic switch reprograms stem cell fate
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57. SQSTM1-dependent autophagic degradation of PKM2 inhibits the production of mature IL1B/IL-1β and contributes to LIPUS-mediated anti-inflammatory effect
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58. Pexophagy: A Model for Selective Autophagy
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59. Pyruvate Kinase M2 Activates mTORC1 by Phosphorylating AKT1S1
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60. Autophagy and bacterial infectious diseases
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61. p62/SQSTM1 involved in cisplatin resistance in human ovarian cancer cells by clearing ubiquitinated proteins
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62. Autophagy of the m6A mRNA demethylase FTO is impaired by low-level arsenic exposure to promote tumorigenesis
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63. The Autophagy-related Protein Kinase Atg1 Interacts with the Ubiquitin-like Protein Atg8 via the Atg8 Family Interacting Motif to Facilitate Autophagosome Formation
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64. Autophagy: links with the proteasome
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65. Cleavage of sequestosome 1/p62 by an enteroviral protease results in disrupted selective autophagy and impaired NFKB signaling
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66. Hydrogen Sulfide Offers Neuroprotection on Traumatic Brain Injury in Parallel with Reduced Apoptosis and Autophagy in Mice
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67. Desmethylclomipramine induces the accumulation of autophagy markers by blocking autophagic flux
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68. Functional Roles of Ubiquitin-Like Domain (ULD) and Ubiquitin-Binding Domain (UBD) Containing Proteins
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69. Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs
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71. Loss of the selective autophagy receptor p62 impairs murine myeloid leukemia progression and mitophagy
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73. Cargo binding to Atg19 unmasks additional Atg8 binding sites to mediate membrane–cargo apposition during selective autophagy
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74. miR-29c-3p inhibits autophagy and cisplatin resistance in ovarian cancer by regulating FOXP1/ATG14 pathway
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75. Genetic screen in Drosophila muscle identifies autophagy-mediated T-tubule remodeling and a Rab2 role in autophagy
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76. SQSTM1/p62 Interacts with HDAC6 and Regulates Deacetylase Activity
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77. Interactions with LC3 and polyubiquitin chains link nbr1 to autophagic protein turnover
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78. S-acylation of p62 promotes p62 droplet recruitment into autophagosomes in mammalian autophagy
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79. The selective autophagy adaptor p62/SQSTM1 forms phase condensates regulated by HSP27 that facilitate the clearance of damaged lysosomes via lysophagy
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80. Combined Bcl-2/Mammalian Target of Rapamycin Inhibition Leads to Enhanced Radiosensitization via Induction of Apoptosis and Autophagy in Non–Small Cell Lung Tumor Xenograft Model
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81. Autophagy-related Protein 8 (Atg8) Family Interacting Motif in Atg3 Mediates the Atg3-Atg8 Interaction and Is Crucial for the Cytoplasm-to-Vacuole Targeting Pathway
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82. Selective Transport of α-Mannosidase by Autophagic Pathways
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83. Selective autophagy
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85. Structural Basis of the Autophagy-Related LC3/Atg13 LIR Complex: Recognition and Interaction Mechanism
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86. Manipulation or capitulation: virus interactions with autophagy
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87. Structural determinants in GABARAP required for the selective binding and recruitment of ALFY to LC3B‐positive structures
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88. ATG4B contains a C-terminal LIR motif important for binding and efficient cleavage of mammalian orthologs of yeast Atg8
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89. CircCDR1as upregulates autophagy under hypoxia to promote tumor cell survival via AKT/ERK½/mTOR signaling pathways in oral squamous cell carcinomas
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90. Autophagy: A double-edged sword in Alzheimer’s disease
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91. Autophagy and polyglutamine diseases
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92. Negative regulation of autophagy by UBA6-BIRC6–mediated ubiquitination of LC3
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93. Recruitment and Activation of the ULK1/Atg1 Kinase Complex in Selective Autophagy
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94. Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein
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96. Plasmodium UIS3 sequesters host LC3 to avoid elimination by autophagy in hepatocytes
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97. Atg8-Family Proteins—Structural Features and Molecular Interactions in Autophagy and Beyond
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98. Characterization of the Interaction of GABARAPL-1 with the LIR Motif of NBR1
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99. Chemopreventative Potential of the Cruciferous Vegetable Constituent Phenethyl Isothiocyanate in a Mouse Model of Prostate Cancer
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100. Structural basis of ATG3 recognition by the autophagic ubiquitin-like protein ATG12
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