Cited by 4Smoking Behavior and CessationMobile Health and mHealth ApplicationsLGBTQ Health, Identity, and Policy

Do Smartphone Apps Impact Long-Term Smoking Cessation for Sexual and Gender Minority Adults? Exploratory Results from a 2-Arm Randomized Trial Comparing Acceptance and Commitment Therapy with Standard US Clinical Practice Guidelines

Open access
Santiago-Torres, Margarita, Mull, Kristin E., Sullivan, Brianna M., Matthews, Alicia K., Skinta, Matthew D., Thrul, Johannes, Vogel, Erin A., Bricker, Jonathan B.·2025·Journal of Homosexuality

Abstract

Sexual and gender minority (SGM) adults face unique challenges in accessing smoking cessation care due to stigma tied to their identities and smoking. While cessation apps show promise in the general population, their efficacy for SGM adults is unclear. This study utilized data from a randomized trial to compare two cessation apps, iCanQuit (Acceptance and Commitment Therapy-based) and QuitGuide (US Clinical Practice Guidelines-based) among 403 SGM adults. The primary outcome was self-reported complete-case 30-day abstinence from cigarette smoking at 12 months. Mediation analyses explored whether interventions operated through acceptance of cues to smoke and app engagement. At 12 months, quit rates did not differ between arms (26% iCanQuit vs. 22% QuitGuide, OR = 1.22; 95% CI: 0.74 to 2.00, p = .43). iCanQuit positively impacted cessation via acceptance of cues to smoke (indirect effect = 0.23; 95% CI: 0.06 to 0.50, p < .001) and demonstrated higher engagement (no. logins, 28.4 vs. 12.1; p < .001) and satisfaction (91% vs. 75%, OR = 4.18; 95% CI: 2.12 to 8.25, p < .001) than QuitGuide. Although quit rates did not differ between arms, acceptance of cues to smoke seemed to play a crucial role in helping SGM adults quit smoking. Future interventions should consider promoting acceptance of cues to smoke in this population.

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Authors
Santiago-Torres, M., Mull, K. E., Sullivan, B. M., Matthews, A. K., Skinta, M. D., Thrul, J., Vogel, E. A., & Bricker, J. B.
Affiliations
  • Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, Washington, USA
  • Fred Hutch Cancer Center (US)
  • University of Illinois Chicago (US)
  • Roosevelt University (US)
  • Johns Hopkins University (US)
  • University of Oklahoma Health Sciences Center (US)
  • University of Washington (US)
Venue
Journal of Homosexuality
Published
2024-02-02
Volume
72
Issue
1
Pages
107-128
ISSN
  • 0091-8369 (ISSN-L)
  • 1540-3602
OpenAlex
W4391486391
Cited by
4
References
55
Citations by year
2026: 2 · 2024: 2
FWCI
1.13
Type
journal article
Language
en
Open access
Locations
  • Journal of Homosexuality (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Cancer Institute (R01 CA192849)
  • National Institute on Drug Abuse (K01DA055073)
Topics
  • Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
  • Health Sciences › Health Professions › General Health Professions › Mobile Health and mHealth Applications
  • Social Sciences › Psychology › Social Psychology › LGBTQ Health, Identity, and Policy
Keywords
smoking cessation, sexual and gender minority adults, acceptance and commitment therapy, app engagement, smoking abstinence, mediation analysis
MeSH terms
Smartphone, Sexual and Gender Minorities, Adult, Female, Humans, Male, Middle Aged, United States, Smoking Cessation, Practice Guidelines as Topic, Mobile Applications, Acceptance and Commitment Therapy

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