Dense amnesia in a professional musician following herpes simplex virus encephalitis
Abstract
We describe the memory functioning of C, a professional musician who became amnesic following herpes simplex encephalitis in 1985. Although transient amnesia in a professional musician has previously been described, this is the first reported case of chronic amnesia in a highly talented professional musician. C is unusual in three respects. First, his amnesia is particularly severe. Second, his amnesia includes semantic as well as episodic memory deficits. Third, he believes he has just woken up and his preoccupation with this state of 'just wakening' has persisted for over 9 years. This appears to be the result of a delusion rather than the consequence of his amnesia.
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A few HSV-1 patients followed longitudinally over long periods display persistent severe anterograde and retrograde amnesia, with relatively preserved remote memories, the hallmark of bilateral hippocampal lesions.
“A few patients followed longitudinally over long periods [39–46], display persistent severe anterograde and retrograde amnesia, with relatively preserved remote memories, the hallmark of bilateral hippocampal lesions.”
From Cognitive decline following acute viral infections: literature review and projections for post-COVID-19 (2022) · cites this paper as [44]
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- Authors
- Wilson, B. A., Baddeley, A. D., & Kapur, N.
- Affiliations
- MRC Applied Psychology Unit
- Wessex Neurological Centre
- Venue
- Journal of Clinical and Experimental Neuropsychology
- Publisher
- Informa UK Limited
- Published
- 1995-10
- Volume
- 17
- Issue
- 5
- Pages
- 668-681
- ISSN
- 0165-0475 (ISSN-L)
- 1380-3395
- 1744-411X
- OpenAlex
- W2012094322
- Cited by
- 116
- References
- 41
- Citations by year
- 2025: 2 · 2024: 4 · 2023: 6 · 2022: 3 · 2021: 2 · 2020: 1 · 2019: 2 · 2018: 3 · 2017: 1 · 2016: 1 · 2015: 1 · 2014: 5 · 2013: 1 · 2012: 1
- FWCI
- 8.08
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Clinical and Experimental Neuropsychology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Wellcome Trust
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Functions and Memory
- Keywords
- herpes simplex encephalitis, episodic memory deficits
- MeSH terms
- Amnesia, Herpes Simplex, Humans, Magnetic Resonance Imaging, Male, Memory, Middle Aged, Music, Psychiatric Status Rating Scales, Reaction Time, Temporal Lobe, Encephalitis, Viral
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