The Covert Learning of Affective Valence Does Not Require Structures in Hippocampal System or Amygdala
Abstract
Following bilateral damage to the entire medial temporal lobe and interconnected cortices in the anterior temporal and medial frontal regions, patient Boswell developed a severe learning defect for all types and levels of Factual knowledge, including faces. In the experiments described here, however, we demonstrate that Boswell can acquire a non conscious bond between entirely new persons and the affective valence they display. The finding is important on the followng accounts. First, Boswell's lesions guarantee that the entorhinal and perirhinal cortices, hippocampus, amygdala, and higher-order neocortices in the anterior temporal region are not required to support this form of covert learning. Second, this demonstration is possible only in a patient such as Boswell, because in individuals with normal or only partially impaired factual learning, fact memory will contaminate the performance.
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A few HSV-1 patients followed longitudinally over long periods display persistent severe anterograde and retrograde amnesia, with relatively preserved remote memories, the hallmark of bilateral hippocampal lesions.
“A few patients followed longitudinally over long periods [39–46], display persistent severe anterograde and retrograde amnesia, with relatively preserved remote memories, the hallmark of bilateral hippocampal lesions.”
From Cognitive decline following acute viral infections: literature review and projections for post-COVID-19 (2022) · cites this paper as [46]
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- Authors
- Tranel, D., & Damasio, A. R.
- Affiliations
- University of Iowa (US)
- ORCID
- Tranel, Daniel
- Venue
- Journal of Cognitive Neuroscience
- Publisher
- MIT Press - Journals
- Published
- 1993-01-01
- Volume
- 5
- Issue
- 1
- Pages
- 79-88
- ISSN
- 0898-929X (ISSN-L)
- 1530-8898
- OpenAlex
- W2000290160
- Cited by
- 134
- References
- 27
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 2 · 2023: 4 · 2022: 4 · 2021: 2 · 2020: 1 · 2019: 2 · 2018: 5 · 2017: 6 · 2016: 4 · 2015: 2 · 2014: 6 · 2013: 3 · 2012: 9
- FWCI
- 1.80
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Cognitive Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Neurological Disorders and Stroke
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
- Life Sciences › Neuroscience › Cognitive Neuroscience › Face Recognition and Perception
- Keywords
- emotional valence, entorhinal cortex, perirhinal cortex, hippocampus, amygdala, face recognition (cognition), emotional learning
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