Prevalence of traumatic brain injury among children, adolescents and young adults: prospective evidence from a birth cohort
Open accessAbstract
Background Little is known about the incidence and prevalence of traumatic brain injury (TBI), particularly for infants, children and young adults. Primary objective The purpose of this study was to provide an accurate estimate of the incidence and prevalence of TBIs for individuals between 0-25 years of age. Method and procedures A birth cohort of 1265 individuals was used, for which information regarding TBI events, both hospitalized and non-hospitalized, had been recorded. Main outcomes and results The average incidence for this age group ranged from 1.10-2.36 per 100 per year, with an overall prevalence of approximately 30%. The most common source of injury was falls for individuals 0-14 years of age and contact sports and motor vehicle accidents for 15-25 year olds. Approximately one third of the individuals who experienced a TBI went on to have one or more additional injuries. Conclusions The incidence rates reported here are much higher than those previously found. It is clear that TBIs constitute a major health issue and therefore it is important to have accurate information to enable planning for primary healthcare services and to inform prevention programmes.
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Data for mild TBI and hypopituitarism are limited.
“The data for mild TBI and hypopituitarism are limited (3).”
From Post-Traumatic Hypopituitarism—Who Should Be Screened, When, and How? (2018) · cites this paper as [3]
The vast majority of the literature on TBI relates to patients who required hospital admission, typically with moderate or severe TBI.
“As a result, the vast majority of the literature on the subject relates to patients who required hospital admission, typically with moderate or severe TBI.”
From Post-Traumatic Hypopituitarism—Who Should Be Screened, When, and How? (2018) · cites this paper as [3]
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Self-citationThe international incidence of traumatic brain injury: a systematic review and meta-analysis
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Frost, R. B., Farrer, T. J., Primosch, M., & Hedges, D. W. (2013) · Neuroepidemiology · doi:10.1159/000343275 · Cited by 361 · see citing works
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Pituitary Dysfunction After Traumatic Brain Injury: A Clinical and Pathophysiological Approach
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Time-Dependent Changes in Microglia Transcriptional Networks Following Traumatic Brain Injury
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The prevalence of traumatic brain injury in the homeless community in a UK city
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Permanent hypopituitarism is rare after structural traumatic brain injury in early childhood
Heather, N. L., Jefferies, C., Hofman, P. L., Derraik, J. G. B., Brennan, C., Kelly, P., Hamill, J. K. M., Jones, R. G., Rowe, D. L., & Cutfield, W. S. (2012) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2011-2284 · Cited by 62 · see citing works
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Post-Traumatic Hypopituitarism—Who Should Be Screened, When, and How?
Quinn, M., & Agha, A. (2018) · Frontiers in Endocrinology · doi:10.3389/fendo.2018.00008 · Cited by 52 · see citing works
“The data for mild TBI and hypopituitarism are limited (3).”
BackgroundPersonnier, C., Crosnier, H., Meyer, P., Chevignard, M., Flechtner, I., Boddaert, N., Breton, S., Mignot, C., Dassa, Y., Souberbielle, J.-C., et al. (2014) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-4129 · Cited by 43 · see citing works
Is routine endocrine evaluation necessary after paediatric traumatic brain injury?
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Teel, E., Brossard-Racine, M., Corbin-Berrigan, L.-A., & Gagnon, I. (2021) · Journal of Head Trauma Rehabilitation · doi:10.1097/htr.0000000000000633 · Cited by 5 · see citing works
- Authors
- McKinlay, A., Grace, R. C., Horwood, L. J., Fergusson, D. M., Ridder, E. M., & MacFarlane, M. R.
- Affiliations
- University of Canterbury (NZ)
- University of Otago (NZ)
- Christchurch Hospital (NZ)
- Corresponding author
- McKinlay, A.
- Venue
- Brain Injury
- Publisher
- Informa UK Limited
- Published
- 2008-01
- Volume
- 22
- Issue
- 2
- Pages
- 175-181
- ISSN
- 0269-9052 (ISSN-L)
- 1362-301X
- OpenAlex
- W2099009590
- Cited by
- 390
- References
- 1
- Citations by year
- 2026: 9 · 2025: 10 · 2024: 17 · 2023: 16 · 2022: 22 · 2021: 21 · 2020: 26 · 2019: 37 · 2018: 30 · 2017: 25 · 2016: 36 · 2015: 29 · 2014: 31 · 2013: 22 · 2012: 20
- FWCI
- 9.65
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- cc-by-nc-nd
- Locations
- Brain Injury (publishedVersion)
- PubMed (publishedVersion)
- Otago University Research Archive (University of Otago) (submittedVersion, cc-by-nc-nd)
- Topics
- Health Sciences › Medicine › Epidemiology › Traumatic Brain Injury Research
- Health Sciences › Medicine › Neurology › Traumatic Brain Injury and Neurovascular Disturbances
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Injury Epidemiology and Prevention
- Keywords
- traumatic brain injury, incidence, prevalence, children, adolescents, young adults, birth cohort, falls, contact sports injuries, motor vehicle accidents, polytrauma, injury prevention
- MeSH terms
- Accident Prevention, Accidental Falls, Accidents, Traffic, Adolescent, Adult, Brain Injuries, Child, Child, Preschool, Female, Humans, Infant, Male, New Zealand, Prospective Studies, Cohort Studies, Trauma Severity Indices, Prevalence
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