Cited by 1,428HIV/AIDS Research and InterventionsMedication Adherence and ComplianceHIV/AIDS drug development and treatment

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Self-reported adherence to antiretroviral medications among participants in HIV clinical trials: The AACTG Adherence Instruments

Chesney, M. A., Ickovics, J. R., Chambers, D. B., Gifford, A. L., Neidig, J., Zwickl, B., Wu, A. W., PATIENT CARE COMMITTEE & ADHERENCE·2000·AIDS Care

DOI 10.1080/09540120050042891

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Abstract

This paper describes the AACTG Adherence Instruments, which are comprised of two self-report questionnaires for use in clinical trials conducted by the Adult AIDS Clinical Trials Group (AACTG). The questionnaires were administered to 75 patients at ten AACTG sites in the USA. All patients were taking combination antiretroviral therapy (ART), including at least one protease inhibitor. Eleven per cent of patients reported missing at least one dose the day before the interview, and 17% reported missing at least one dose during the two days prior. The most common reasons for missing medications included 'simply forgot' (66%) and a number of factors often associated with improved health, including being busy (53%), away from home (57%) and changes in routine (51%). Less adherent patients reported lower adherence self-efficacy (p = 0.006) and were less sure of the link between non-adherence and the development of drug resistance (p = 0.009). They were also more likely to consume alcohol, to be employed outside the home for pay and to have enrolled in clinical trials to gain access to drugs (all p < 0.05). Twenty-two per cent of patients taking drugs requiring special instructions were unaware of these instructions. Each questionnaire took approximately ten minutes to complete. Responses to the questionnaires were favourable. These questionnaires have been included in six AACTG clinical trials to date and have been widely disseminated to investigators both in the USA and abroad.

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A Global Measure of Perceived Stress
Cohen, S., Kamarck, T., & Mermelstein, R. (1983) · Journal of Health and Social Behavior · doi:10.2307/2136404 · Cited by 32,807
Declining Morbidity and Mortality among Patients with Advanced Human Immunodeficiency Virus Infection
Palella, F. J., Delaney, K. M., Moorman, A. C., Loveless, M. O., Fuhrer, J., Satten, G. A., Aschman, D. J., & Holmberg, S. D. (1998) · New England Journal of Medicine · doi:10.1056/nejm199803263381301 · Cited by 9,393
Survey Research Methods.
Hesselbart, S., & Fowler, F. J. (1985) · Journal of the American Statistical Association · doi:10.2307/2288598 · Cited by 4,767
Compliance in Health Care
Haynes, R. B., Taylor, D. W., & Sackett, D. L. (1979) · DigitalGeorgetown (Georgetown University Library) · Cited by 1,627
Age and Depression
Mirowsky, J., & Ross, C. E. (1992) · Journal of Health and Social Behavior · doi:10.2307/2137349 · Cited by 856
Sexual Transmission of an HIV-1 Variant Resistant to Multiple Reverse-Transcriptase and Protease Inhibitors
Hecht, F. M., Grant, R. M., Petropoulos, C. J., Dillon, B. A., Chesney, M. A., Tian, H., Hellmann, N. S., Bandrapalli, N. I., Digilio, L., Branson, B. M., et al. (1998) · New England Journal of Medicine · doi:10.1056/nejm199807303390504 · Cited by 443
Self-citation
Patient Compliance and Drug Failure in Protease Inhibitor Monotherapy
Vanhove, G. F. (1996) · JAMA · doi:10.1001/jama.1996.03540240033024 · Cited by 193
Protease Inhibitors in the Homeless
Bangsberg, D. R. (1997) · JAMA · doi:10.1001/jama.1997.03550010077044 · Cited by 150
Compliance in clinical trials
Besch, C. L. (1995) · AIDS · doi:10.1097/00002030-199501000-00001 · Cited by 148
Predictors of patient adherence: Patient characteristics.
Dunbar, J. (1990) · Cited by 83

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Method
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“AIDS Clinical Trials Group HIV Symptom Checklist (ACTG; Chesney et al., 2000)—The ACTG questionnaire includes a list of 20 symptoms associated with HIV infection.”
BackgroundMethodInfluential
Measuring Adherence to Antiretroviral Medications in Clinical Trials
Miller, L. G., & Hays, R. D. (2000) · HIV Clinical Trials · doi:10.1310/enxw-95pb-5ngw-1f40 · Cited by 105
Validity of Medication Adherence Self-Reports in Adults With Type 2 Diabetes
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Self-citation
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“Antiretroviral medication adherence—Self-reported ART adherence was assessed over a three-day period using an adherence survey developed for use in AIDS Clinical Trials (Chesney et al., 2000).”
MethodSelf-citation
Adherence to antiretroviral therapy for HIV / AIDS in Latin America and the Caribbean: Systematic review and meta‐analysis
Costa, J. D. M., Torres, T. S., Coelho, L. E., & Luz, P. M. (2018) · Journal of the International AIDS Society · doi:10.1002/jia2.25066 · Cited by 102
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Method
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“This has been reported by patients as a reason for missing doses (17,21,34).”
BackgroundResultInfluential
Systematic Review: Effect of Alcohol Intake on Adherence to Outpatient Medication Regimens for Chronic Diseases
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MethodInfluential
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The relationship of acceptance or denial of HIV-status to antiretroviral adherence among adult HIV patients in urban Botswana
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Method
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Bonn‐Miller, M. O., Oser, M. L., Bucossi, M. M., & Trafton, J. A. (2012) · Journal of Behavioral Medicine · doi:10.1007/s10865-012-9458-5 · Cited by 99
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Method
Modeling the effects of spirituality/religion on patients’ perceptions of living with HIV/AIDS
Szaflarski, M., Ritchey, P. N., Leonard, A. C., Mrus, J. M., Peterman, A. H., Ellison, C. G., McCullough, M. E., & Tsevat, J. (2006) · Journal of General Internal Medicine · doi:10.1111/j.1525-1497.2006.00646.x · Cited by 100
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“Per patient self-report, “forgetting” is among the most frequently perceived causes of missing antiretroviral (ARV) doses (Chesney et al., 2000).”
BackgroundResult
Major Depression in Patients with HIV/AIDS and Substance Abuse
Berger-Greenstein, J. A., Cuevas, C. A., Brady, S. M., Trezza, G. R., Richardson, M. A., & Keane, T. M. (2007) · AIDS Patient Care and STDs · doi:10.1089/apc.2006.0153 · Cited by 98
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Robbins, G. K., Daniels, B., Zheng, H. W., Chueh, H. C., Meigs, J. B., & Freedberg, K. A. (2006) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/01.qai.0000248351.10383.b7 · Cited by 97
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Sangeda, R. Z., Mosha, F. S., Prosperi, M., Aboud, S., Vercauteren, J., Camacho, R. J., Lyamuya, E., Wijngaerden, E. V., & Vandamme, A. (2014) · BMC Public Health · doi:10.1186/1471-2458-14-1035 · Cited by 96
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“We estimated the prevalence of self-reported 100% adherence to ART doses (dose adherence) in the past 3 days using AIDS Clinical Trials Group measures (Chesney et al., 2000).”
Community-Based Participatory Research
Springer, M. V., & Skolarus, L. E. (2019) · Stroke · doi:10.1161/strokeaha.118.024241 · Cited by 99
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Chandwani, S., Koenig, L. J., Sill, A. M., Abramowitz, S., Conner, L. C., & D’Angelo, L. J. (2012) · Journal of Adolescent Health · doi:10.1016/j.jadohealth.2011.12.013 · Cited by 95
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Method
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Ford, N. P., Darder, M., Spelman, T. D., Maclean, E., Mills, E. J., & Boulle, A. (2010) · PLoS ONE · doi:10.1371/journal.pone.0010460 · Cited by 94
“The adherence survey included all consenting patients enrolled onto antiretroviral therapy at primary care clinics in Khayelitshsa township, South Africa between May 2002 and March 2004. Self-reported adherence was assessed by a dedicated study team unrelated to the provision of clinical care using a modified version…”
Method
ACTG A5353: A Pilot Study of Dolutegravir Plus Lamivudine for Initial Treatment of Human Immunodeficiency Virus-1 (HIV-1)–infected Participants With HIV-1 RNA <500000 Copies/mL
Taiwo, B., Zheng, L., Stefanescu, A. R., Nyaku, A. N., Bezins, B., Wallis, C. L., Godfrey, C. C., Sax, P. E., Acosta, E. P., Haas, D. W., et al. (2017) · Clinical Infectious Diseases · doi:10.1093/cid/cix1083 · Cited by 93
Posttraumatic stress disorder symptoms, salivary cortisol, medication adherence, and CD4 levels in HIV-positive individuals
Delahanty, D. L., Bogart, L. M., & Figler, J. L. (2003) · AIDS Care · doi:10.1080/09540120410001641084 · Cited by 93
Personality and HIV Disease Progression: Role of NEO-PI-R Openness, Extraversion, and Profiles of Engagement
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“Adherence Prescribed medications and adherence were assessed through interviewer administered AIDS Clinical Trials Group Adherence Measure (34).”
Method
Determinants of HAART discontinuation among injection drug users
Kerr, T. H., Marshall, A., Walsh, J. C., Palepu, A., TYNDALL, M. W., Montaner, J. S. G., Hogg, R. S., & Wood, E. (2005) · AIDS Care · doi:10.1080/09540120412331319778 · Cited by 93
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Development and validation of the Beliefs and Behaviour Questionnaire (BBQ)
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“7 Only four self-report questionnaires—the simplified medication adherence questionnaire (SMAQ), 16 the visual analogue scale (VAS), 17 the Adult AIDS Clinical Trials Group (AACTG) questionnaire, 18 and the Self-Reported Adherence (SERAD) 19 —have been validated against electronic monitoring.”
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Method
Stigma Mediates the Relationship Between Self-Efficacy, Medication Adherence, and Quality of Life Among People Living with HIV/AIDS in China
Li, X., Huang, L., Wang, H., Fennie, K., He, G., & Williams, A. B. (2011) · AIDS Patient Care and STDs · doi:10.1089/apc.2011.0174 · Cited by 89
The impact of illicit drug use and substance abuse treatment on adherence to HAART
Hicks, P. L., Mulvey, K. P., Chander, G., Fleishman, J. A., Josephs, J. S., Korthuis, P. T., Hellinger, J., Gaist, P., Gebo, K. A., & for the HIV Research Network (2007) · AIDS Care · doi:10.1080/09540120701351888 · Cited by 89
“(Chesney et al., 2000).”
Piloting a Peer-Driven Intervention Model to Increase Access and Adherence to Antiretroviral Therapy and HIV Care among Street-Entrenched HIV-Positive Women in Vancouver
Deering, K., Shannon, K., Sinclair, H., Parsad, D., Gilbert, E., & TYNDALL, M. W. (2009) · AIDS Patient Care and STDs · doi:10.1089/apc.2009.0022 · Cited by 89
Telephone Support to Improve Antiretroviral Medication Adherence
Reynolds, N. R., Testa, M. A., Su, M., Chesney, M. A., Neidig, J. L., Frank, I., Smith, S. R., Ickovics, J. R., & Robbins, G. K. (2008) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0b013e3181582d54 · Cited by 89
Self-citation
Evaluation of WebEase: an epilepsy self-management Web site
DiIorio, C. K., Escoffery, C., McCarty, F., Yeager, K. A., Henry, T. R., Koganti, A., Reisinger, E. L., & Wexler, B. (2008) · Health Education Research · doi:10.1093/her/cyn012 · Cited by 89
“‘Self-report adherence’ was measured using the 15-item USCF Adherence Questionnaire and the five-item Antiretroviral General Adherence Scale (AGAS), both of which were developed for use with other medications and revised for use with antiepileptic drugs [30, 31].”
Method
Effect of a Coordinated Community and Chronic Care Model Team Intervention vs Usual Care on Systolic Blood Pressure in Patients With Stroke or Transient Ischemic Attack
Towfighi, A., Cheng, E. M., Ayala-Rivera, M., Barry, F., McCreath, H. E., Ganz, D. A., Lee, M. L., Sanossian, N., Mehta, B. K., Dutta, T. M., et al. (2021) · JAMA Network Open · doi:10.1001/jamanetworkopen.2020.36227 · Cited by 87
Interpreting cerebrospinal fluid pleocytosis in HIV in the era of potent antiretroviral therapy
Marra, C. M., Maxwell, C. L., Collier, A. C., Robertson, K. R., & Imrie, A. A. (2007) · BMC Infectious Diseases · doi:10.1186/1471-2334-7-37 · Cited by 88
“At each visit, they underwent a standardized neurological and medication history; neurological examination; brief neuropsychological test battery that included timed gait, grooved pegboard with the dominant hand, finger tapping with the nondominant hand and digit symbol; assessment of antiretroviral drug adherence [8]…”
Method
Long-Term Adherence to Antiretroviral Treatment and Program Drop-Out in a High-Risk Urban Setting in Sub-Saharan Africa: A Prospective Cohort Study
Unge, C., Södergård, B., Marrone, G., Thorson, A. E., Lukhwaro, A., Carter, J. Y., Ilako, F., & Ekström, A. M. (2010) · PLoS ONE · doi:10.1371/journal.pone.0013613 · Cited by 87
“The follow-up questionnaire focused on self-reported adherence to ART (as measured by a modified AACTG questionnaire [23]).”
BackgroundMethodInfluential
High Levels of Adherence and Viral Suppression in a Nationally Representative Sample of HIV-Infected Adults on Antiretroviral Therapy for 6, 12 and 18 Months in Rwanda
Elul, B., Basinga, P., Nuwagaba‐Biribonwoha, H., Saito, S., Horowitz, D., Nash, D., Mugabo, J., Mugisha, V., Rugigana, E., Nkunda, R., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0053586 · Cited by 87
Testing a peer-based symptom management intervention for women living with HIV/AIDS
Webel, A. R. (2010) · AIDS Care · doi:10.1080/09540120903214389 · Cited by 87
“The ACTGrev is a self-report measure of reasons for missing medications (Chesney et al., 2000; Holzemer et al., 2006).”
Background
Testing a Nurse-Tailored HIV Medication Adherence Intervention
Holzemer, W. L., Henry, S. B., Portillo, C. J., Grimes, R., Welch, J., Wantland, D. J., & Mullan, J. T. (2006) · Nursing Research · doi:10.1097/00006199-200605000-00005 · Cited by 86
“’’ Evidence for the construct validity of ACTGRev as a whole has been established (Chesney et al., 2000), but no validity and reliability information related specifically to the reasons for missing medication scale was reported.”
BackgroundInfluential
Management of HIV-related stigma and adherence to HAART: Evidence from a large representative sample of outpatients attending French hospitals (ANRS-EN12-VESPA 2003)
Peretti‐Watel, P., Spire, B., Pierret, J., Lert, F., Obadia, Y., & The VESPA Group (2006) · AIDS Care · doi:10.1080/09540120500456193 · Cited by 87
“Previous studies found that not wanting others to see one taking medication is often reported as a reason for missing doses (Chesney et al., 2000; Gifford et al., 2000), and a few quantitative studies have concluded that nonadherence to HAART was positively correlated to concealment of one’s…”
Background
Relationship Between Routinization of Daily Behaviors and Medication Adherence in HIV-Positive Drug Users
Wagner, G. J., & Ryan, G. W. (2004) · AIDS Patient Care and STDs · doi:10.1089/1087291041518238 · Cited by 87
Predictors of Self-Reported Antidepressant Adherence
Burra, T. A., Chen, E., McIntyre, R. S., Grace, S. L., Blackmore, E. R., & Stewart, D. E. (2007) · Behavioral Medicine · doi:10.3200/bmed.32.4.127-134 · Cited by 86
Spiritual coping predicts CD4-cell preservation and undetectable viral load over four years
Kremer, H., Ironson, G. H., Kaplan, L. M., Stuetzele, R., Baker, N., & FLETCHER, M. A. (2014) · AIDS Care · doi:10.1080/09540121.2014.952220 · Cited by 86
“We assessed taking/adhering to ART with the adherence questionnaire of the AIDS Clinical Trials Group (Chesney et al., 2000).”
Method
Incomplete adherence among treatment-experienced adults on antiretroviral therapy in Tanzania, Uganda and Zambia
Denison, J., Koole, O., Tsui, S., Menten, J., Torpey, K., van Praag, E., Mukadi, Y., Colebunders, R., Auld, A., Agolory, S., et al. (2015) · AIDS (London) · doi:10.1097/qad.0000000000000543 · Cited by 86
“Participants reported their 3-day adherence using the Adult AIDS Clinical Trials Group (AACTG) measure specifying the numbers of tablets for each drug missed each day [21], followed by an aggregate question of how many ART tablets missed in the previous 30 days.”
Design of a randomized trial to evaluate the influence of mobile phone reminders on adherence to first line antiretroviral treatment in South India - the HIVIND study protocol
the HIVIND study team, Costa, A. D., Shet, A., Kumarasamy, N., Ashorn, P., Eriksson, B., Bogg, L., & Diwan, V. K. (2010) · BMC Medical Research Methodology · doi:10.1186/1471-2288-10-25 · Cited by 88
Prevalence and Correlates of Nonadherence to Antiretroviral Therapy in a Population of HIV Patients Using Medication Event Monitoring System ®
Deschamps, A., Graeve, V. D., Wijngaerden, E. V., Saar, V. D., Vandamme, A., Vaerenbergh, K. V., Ceunen, H., Bobbaers, H., Peetermans, W. E., Vleeschouwer, P. D., et al. (2004) · AIDS Patient Care and STDs · doi:10.1089/apc.2004.18.644 · Cited by 85
“71 Clear instructions about how to take medicines, 55,72 adequate knowledge about the relationship between adherence and viral load 27,30,44 and better medical follow-up, 27,42,69 are all related to better adherence.”
Influential
Association of stereotypes about physicians to health care satisfaction, help-seeking behavior, and adherence to treatment
Bogart, L. M., Bird, S. T., Walt, L. C., Delahanty, D. L., & Figler, J. L. (2003) · Social Science & Medicine · doi:10.1016/s0277-9536(03)00277-6 · Cited by 87
Assessing medication adherence self-efficacy among low-literacy patients: development of a pictographic visual analogue scale
Kalichman, S. C. (2004) · Health Education Research · doi:10.1093/her/cyg106 · Cited by 83
Depression in patients with HIV is under‐diagnosed: a cross‐sectional study in Denmark
Rodkjær, L. Ø., Laursen, T. L., Balle, N., & Sodemann, M. (2009) · HIV Medicine · doi:10.1111/j.1468-1293.2009.00741.x · Cited by 84
Increase in Single-Tablet Regimen Use and Associated Improvements in Adherence-Related Outcomes in HIV-Infected Women
Hanna, D. B., Hessol, N. A., Golub, E. T., Cocohoba, J. M., Cohen, M. H., Levine, A. M., Wilson, T. E., Young, M., Anastos, K., & Kaplan, R. C. (2013) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0000000000000082 · Cited by 84
“ART adherence is assessed in the WIHS by asking the participant the percentage of time during the past 6 months that ART was taken as prescribed,(26) categorized as: 100% of the time, 95–99%, 75–94%, and 75%.”
MethodInfluential
Psychosocial and Neurohormonal Predictors of HIV Disease Progression (CD4 Cells and Viral Load): A 4 Year Prospective Study
Ironson, G. H., O’Cleirigh, C. M., Kumar, M., Kaplan, L. M., Balbin, E., Kelsch, C. B., Fletcher, M. A., & Schneiderman, N. (2014) · AIDS and Behavior · doi:10.1007/s10461-014-0877-x · Cited by 87
“adherence was assessed through interviewer administered AIDS Clinical Trials Group Adherence measure [47].”
Adherence to HIV antiretroviral therapy
Heyer, A., & Ogunbanjo, G. A. (2006) · South African Family Practice · doi:10.1080/20786204.2006.10873433 · Cited by 84
Cohort Profile: The Ontario HIV Treatment Network Cohort Study (OCS)
Rourke, S. B., Gardner, S. L., Burchell, A. N., Raboud, J., Rueda, S., Bayoumi, A. M., Loutfy, M. R., Cooper, C., Smieja, M., Taylor, D., et al. (2012) · International Journal of Epidemiology · doi:10.1093/ije/dyr230 · Cited by 84
Violence, Coping, and Consistent Medication Adherence in HIV-Positive Couples
Lopez, E. J., Jones, D. L., Villar-Loubet, O. M., Arheart, K. L., & Weiss, S. M. (2010) · AIDS Education and Prevention · doi:10.1521/aeap.2010.22.1.61 · Cited by 84
“ACTG Questionnaire for Adherence to Anti-HIV Medications—Adherence was measured by 4-day self-report using the ACTG (AIDS Clinical Trials Group) Questionnaire for Adherence to Anti-HIV Medications (4 days; Chesney et al., 2000).”
Method
Regimen Simplification to Atazanavir-Ritonavir Alone as Maintenance Antiretroviral Therapy After Sustained Virologic Suppression
Swindells, S. (2006) · JAMA · doi:10.1001/jama.296.7.806 · Cited by 84
Effect of rifampicin-based antitubercular therapy and the cytochrome P450 2B6 516G>T polymorphism on efavirenz concentrations in adults in South Africa.
Cohen, K., Grant, A. D., Dandara, C., McIlleron, H., Pemba, L., Fielding, K., Charalombous, S., Churchyard, G., Smith, P. J., & Maartens, G. (2009) · PubMed · Cited by 83
ART adherence, demographic variables and CD4 outcome among HIV-positive patients on antiretroviral therapy in Chennai, India
Safren, S. A., Kumarasamy, N., James, R., Raminani, S. R., Solomon, S., & Mayer, K. H. (2005) · AIDS Care · doi:10.1080/09540120500038439 · Cited by 83
“Catz et al, 2000 ; Chesney et al, 2000 ; Holzemer, et al, 2000 ), demographic variables were not associated with adherence in this study of patients in India.”
Result
How Qualitative Methods Contribute to Understanding Combination Antiretroviral Therapy Adherence
Sankar, A., Golin, C. E., Simoni, J. M., LUBORSKY, M. R., & Pearson, C. R. (2006) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/01.qai.0000248341.28309.79 · Cited by 83
Outcomes of highly active antiretroviral therapy in the context of universal access to healthcare: the U.S. Military HIV Natural History Study
Marconi, V. C., Grandits, G., Weintrob, A., Chun, H., Landrum, M. L., Ganesan, A., Okulicz, J. F., Crum‐Cianflone, N. F., O’Connell, R. J., Lifson, A. R., et al. (2010) · AIDS Research and Therapy · doi:10.1186/1742-6405-7-14 · Cited by 82
Psychological well-being and adherence to antiretroviral therapy among adolescents living with HIV in Zambia
Okawa, S., Mwanza-Kabaghe, S., Mwiya, M., Kikuchi, K., Jimba, M., Kankasa, C., & Ishikawa, N. (2018) · AIDS Care · doi:10.1080/09540121.2018.1425364 · Cited by 83
“We utilized “self-report” in measuring adherence to ART (Chesney et al., 2000).”
Method
Association of social stress, illicit drug use, and health beliefs with nonadherence to antiretroviral therapy
Gebo, K. A., Keruly, J. C., & Moore, R. D. (2003) · Journal of General Internal Medicine · doi:10.1046/j.1525-1497.2003.10801.x · Cited by 82
Patient Reported Outcomes in Routine Care: Advancing Data Capture for HIV Cohort Research
Kozak, M. S., Mugavero, M. J., Ye, J., Aban, I., Lawrence, S. T., Nevin, C. R., Raper, J. L., McCullumsmith, C. B., Schumacher, J. E., Crane, H. M., et al. (2011) · Clinical Infectious Diseases · doi:10.1093/cid/cir727 · Cited by 82
Antiretroviral Concentrations in Small Hair Samples as a Feasible Marker of Adherence in Rural Kenya
Hickey, M. D., Salmen, C. R., Tessler, R. A., Omollo, D. O., Bacchetti, P., Magerenge, R., Mattah, B. J., Salmen, M. R., Zoughbie, D. E., Fiorella, K. J., et al. (2014) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0000000000000154 · Cited by 83
Addressing the intersection between alcohol consumption and antiretroviral treatment: needs assessment and design of interventions for primary healthcare workers, the Western Cape, South Africa
Schneider, M., Chersich, M., Temmerman, M., & Parry, C. D. H. (2016) · Globalization and Health · doi:10.1186/s12992-016-0201-9 · Cited by 82
“The Adult AIDS Clinical Trials Group, [11] an instrument for measuring levels of adherence to ART and reasons for missed doses, was not used to analyse the transcripts but could be considered for use in future research in this area focusing on adherence measurement.”
Method
Pill taking ‘routinization’: a critical factor to understanding episodic medication adherence
Ryan, G. W., & Wagner, G. J. (2003) · AIDS Care · doi:10.1080/09540120310001618649 · Cited by 81
Data Collection and Harmonization in HIV Research: The Seek, Test, Treat, and Retain Initiative at the National Institute on Drug Abuse
Chandler, R. K., Kahana, S. Y., Fletcher, B. W., Jones, D. J., Finger, M. S., Aklin, W. M., Hamill, K., & Webb, C. (2015) · American Journal of Public Health · doi:10.2105/ajph.2015.302788 · Cited by 80
Medication Regimen Complexity Measured by MRCI: A Systematic Review to Identify Health Outcomes
da Conceição, V. A., Rocha, K. S. S., Silva, F. V. N., Silva, R. D. O. S., da Silva, D. T., & de Lyra, D. P. (2018) · Annals of Pharmacotherapy · doi:10.1177/1060028018773691 · Cited by 80
Adherence to antiretroviral therapy and its determinants in children with human immunodeficiency virus infection: a multicentre, national study
Giacomet, V., Albano, F., Starace, F., de Franciscis, A., Giaquinto, C., Gattinara, G. C., Bruzzese, E., Gabiano, C., Galli, L., Viganò, M., et al. (2003) · Acta Paediatrica · doi:10.1111/j.1651-2227.2003.tb00822.x · Cited by 80
“Since adherence rates 95% of prescribed doses have been associated with optimal virological outcome (13), children were defined as adherent if they had taken no less than 95% of all prescribed doses of antiretroviral therapy in the past 4 d (9, 14).”
Background
Patient and Regimen Characteristics Associated with Self-Reported Nonadherence to Antiretroviral Therapy
Sullivan, P. S., Campsmith, M., Nakamura, G. V., Begley, E. B., Schulden, J. D., & Nakashima, A. K. (2007) · PLoS ONE · doi:10.1371/journal.pone.0000552 · Cited by 80
Behavioral Aspects of HIV Care: Adherence, Depression, Substance Use, and HIV-Transmission Behaviors
Berg, C. J., Michelson, S. E., & Safren, S. A. (2007) · Infectious Disease Clinics of North America · doi:10.1016/j.idc.2007.01.005 · Cited by 81
HIV Stigma Among Substance Abusing People Living with HIV/AIDS: Implications for HIV Treatment
Levi-Minzi, M. A., & Surratt, H. L. (2014) · AIDS Patient Care and STDs · doi:10.1089/apc.2014.0076 · Cited by 80
Medication Adherence in Psychopharmacologically Treated Adults With ADHD
Safren, S. A., Duran, P., Yovel, I., Perlman, C. A., & Sprich, S. (2007) · Journal of Attention Disorders · doi:10.1177/1087054706292165 · Cited by 81
“Adherence was assessed using a modified version of the adherence questionnaire for HIV/AIDS that is used by the AIDS Clinical Trials Group (Chesney et al., 2000) that we (Safren et al., 2001) and others have successfully implemented in HIV research.”
Method
Trauma History and Depression Predict Incomplete Adherence to Antiretroviral Therapies in a Low Income Country
Whetten, K., Shirey, K., Pence, B. W., Yao, J., Thielman, N. M., Whetten, R., Adams, J., Agala, C. B., Ostermann, J., O’Donnell, K., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0074771 · Cited by 81
Baseline HIV-1 resistance, virological outcomes, and emergent resistance in the SECOND-LINE trial: an exploratory analysis
Boyd, M. A., Moore, C. L., Molina, J., Wood, R., Madero, J. S., Wolff, M. J., Ruxrungtham, K., Losso, M. H., Renjifo, B., Teppler, H., et al. (2015) · The Lancet HIV · doi:10.1016/s2352-3018(14)00061-7 · Cited by 79
Concordance of Adherence Measurement Using Self-Reported Adherence Questionnaires and Medication Monitoring Devices: An Updated Review
Monnette, A. M., Zhang, Y., Shao, H., & Shi, L. (2017) · PharmacoEconomics · doi:10.1007/s40273-017-0570-9 · Cited by 84
“The AACTG instrument was developed by the AIDS Clinical Trials Group (ACTG) Recruitment, Adherence and Retention Subcommittee for HIV populations [27].”
Method
Treatment-Related Factors and Highly Active Antiretroviral Therapy Adherence
Trotta, M. P., Ammassari, A., Melzi, S., Zaccarelli, M., Ladisa, N., Sighinolfi, L., Mura, M. S., Monforte, A. D., & Antinori, A. (2002) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/00126334-200212153-00008 · Cited by 79
Is Patients’ Preferred Involvement in Health Decisions Related to Outcomes for Patients with HIV?
Beach, M. C., Duggan, P. S., & Moore, R. D. (2007) · Journal of General Internal Medicine · doi:10.1007/s11606-007-0241-1 · Cited by 78

Authors: Chesney, M. A., Ickovics, J. R., Chambers, D. B., Gifford, A. L., Neidig, J., Zwickl, B., Wu, A. W., & PATIENT CARE COMMITTEE & ADHERENCE
Affiliations: University of California, San Francisco (US)
Yale University (US)
University of California San Diego (US)
The Ohio State University (US)
Indiana University Indianapolis (US)
Johns Hopkins University (US)
ORCID: Chesney, M. A.
Ickovics, J. R.
Gifford, A. L.
Wu, A. W.
Venue: AIDS Care
Publisher: Informa UK Limited
Published: 2000-06
Volume: 12
Issue: 3
Pages: 255-266
ISSN: 0954-0121 (ISSN-L)
1360-0451
DOI: 10.1080/09540120050042891
OpenAlex: W2088423598
Cited by: 1,428
References: 12
Citations by year: 2026: 14 · 2025: 28 · 2024: 29 · 2023: 29 · 2022: 40 · 2021: 53 · 2020: 51 · 2019: 55 · 2018: 61 · 2017: 66 · 2016: 67 · 2015: 76 · 2014: 81 · 2013: 84 · 2012: 74
FWCI: 27.22
Type: journal article
Language: en
Open access: closed
Locations: AIDS Care (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute of Mental Health (P50-MH42459, P30MH059037, P50MH042459, P30-MH 59037)
National Institute of Allergy and Infectious Diseases (U01AI-38858, U01AI038858)
Topics: Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
Health Sciences › Medicine › Infectious Diseases › HIV/AIDS drug development and treatment
Keywords: antiretroviral therapy adherence, HIV, self-report questionnaire, medication non-adherence, adherence self-efficacy, alcohol consumption, protease inhibitors, clinical trial participants, questionnaire development
MeSH terms: Adult, Alcohol Drinking, Clinical Trials as Topic, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Patient Compliance, Pilot Projects, Surveys and Questionnaires, Risk Factors, Socioeconomic Factors, HIV Infections, Anti-HIV Agents, Substance-Related Disorders

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Self-reported adherence to antiretroviral medications among participants in HIV clinical trials: The AACTG Adherence Instruments

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