The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.
Biopsychosocial correlates of fatigue in young adult survivors of childhood traumatic brain injury: A prospective cohort study
Open accessAbstract
This prospective cohort study aimed to evaluate the potential role of injury, socio-demographic and individual psychological factors in predicting long-term fatigue outcomes in young adult survivors of childhood TBI at 16-years post-injury. The study included 51 young adults diagnosed with childhood TBI from 2-12 years of age. Twenty age-and-sex-matched controls were included for comparison. Findings showed that almost one-in-four TBI participants (24%) endorsed clinically elevated fatigue at 16-years post-injury. Despite the relatively large proportion of TBI participants endorsing clinically significant fatigue, group comparisons revealed that the TBI and control groups did not significantly differ on fatigue symptom severity or rates of clinically elevated fatigue. For the TBI group, post-injury fatigue was significantly associated with socio-demographic and psychological factors, including lower educational level, higher depression symptom severity, and more frequent substance use. Higher fatigue was also associated with lower self-reported quality of life (QoL) in the physical, psychological, and environmental domains, even after controlling for depressive symptom severity, socio-demographic, and injury-related factors. Overall, findings show that a substantial proportion of young adults with a history of childhood TBI experience clinically elevated fatigue at 16-years post-injury. Identification and treatment of modifiable risk-factors (e.g. depression symptoms, substance use) has potential to reduce fatigue.
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Metadata
- Authors
- Lee Marmol, N., Ryan, N. P., Sood, N., Morrison, E., Botchway-Commey, E., Anderson, V., & Catroppa, C.
- Affiliations
- Brain and Mind Research, Murdoch Children’s Research Institute, Parkville, Australia
- Deakin University (AU)
- Murdoch Children's Research Institute (AU)
- The University of Melbourne (AU)
- Royal Children's Hospital (AU)
- Corresponding author
- Ryan, Nicholas P.
- ORCID
- Venue
- Neuropsychological Rehabilitation
- Publisher
- Informa UK Limited
- Published
- 2024-02-21
- Volume
- 35
- Issue
- 1
- Pages
- 1-18
- ISSN
- 0960-2011 (ISSN-L)
- 1464-0694
- OpenAlex
- W4391996059
- Cited by
- 3
- References
- 45
- Citations by year
- 2026: 2 · 2025: 1
- FWCI
- 0.71
- Type
- journal article
- Language
- en
- Open access
- green
- figshare.com
- Licence
- cc-by
- Locations
- Neuropsychological Rehabilitation (publishedVersion)
- PubMed (publishedVersion)
- Figshare (submittedVersion, cc-by)
- Topics
- Health Sciences › Medicine › Clinical Neurology › Traumatic Brain Injury Research
- Health Sciences › Medicine › Clinical Neurology › Long-Term Effects of COVID-19
- Health Sciences › Medicine › Clinical Neurology › Traumatic Brain Injury and Neurovascular Disturbances
- Keywords
- pediatric traumatic brain injury, young adult survivors, biopsychosocial factors, depressive symptoms, substance use, quality of life, educational attainment, long-term outcomes, risk factors for fatigue
- MeSH terms
- Brain Injuries, Traumatic, Adolescent, Adult, Child, Child, Preschool, Depression, Fatigue, Female, Humans, Male, Prospective Studies, Quality of Life, Severity of Illness Index, Survivors, Young Adult
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