The DOI matches its Crossref record; 148 of the 150 references it cites were found in a registry or an index.
Biomarkers of Fruit and Vegetable Intake in Human Intervention Studies: A Systematic Review
Abstract
Observational evidence consistently shows that consumption of a diet rich in fruit and vegetables may offer protection against diseases such as cardiovascular disease and cancer. Assessment of dietary intake is complex and prone to many sources of error. More objective biomarkers of fruit and vegetable intake are therefore of interest. The aim of this review is to examine the usefulness of the main biomarkers of fruit and vegetable intake to act as objective indicators of compliance in dietary intervention studies. A comprehensive search of the literature was conducted using six databases. Suitable papers were selected and relevant data extracted. The papers were categorized into 3 sub-groups: whole diet interventions; mixed fruit and vegetable interventions; and studies involving individual varieties of fruits or vegetables. Ninety-six studies were included in the review. Overall, the most commonly measured, and most consistently responsive, biomarkers were the carotenoids and vitamin C. Based on the results of this systematic review, it remains prudent to measure a panel of biomarkers in fruit and vegetable intervention studies. The only possible exception to this is "fruit only" intervention studies where assessment of vitamin C alone may suffice.
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“polyphenols, carotenoids, and vitamin C for fruit and vegetables (17,18)”
From The food metabolome: a window over dietary exposure (2014) · cites this paper as [17]
Citations
Cites
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Cited by
Sorted by citations
The food metabolome: a window over dietary exposure
Scalbert, A., Brennan, L., Manach, C., Andres-Lacueva, C., Dragsted, L. O., Draper, J., Rappaport, S. M., van der Hooft, J. J., & Wishart, D. S. (2014) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.113.076133 · Cited by 519
The Health Potential of Fruits and Vegetables Phytochemicals: Notable Examples
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Validation of biomarkers of food intake—critical assessment of candidate biomarkers
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Nutritional Importance of Carotenoids and Their Effect on Liver Health: A Review
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Metadata
- Authors
- Baldrick, F. R., Woodside, J. V., Elborn, J. S., Young, I. S., & McKinley, M. C.
- Affiliations
- Queen's University Belfast (GB)
- Venue
- Critical Reviews in Food Science and Nutrition
- Publisher
- Informa UK Limited
- Published
- 2011-10
- Volume
- 51
- Issue
- 9
- Pages
- 795-815
- ISSN
- 1040-8398 (ISSN-L)
- 1549-7852
- OpenAlex
- W2041984497
- Cited by
- 109
- References
- 150
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 3 · 2023: 5 · 2022: 12 · 2021: 10 · 2020: 10 · 2019: 2 · 2018: 11 · 2017: 5 · 2016: 7 · 2015: 12 · 2014: 9 · 2013: 9 · 2012: 9
- FWCI
- 1.36
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Critical Reviews in Food Science and Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Research Portal (Queen's University Belfast) (submittedVersion)
- Funders
- Economic and Social Research Council (ES/G007438/1)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Health Sciences › Medicine › Biochemistry (medical) › Phytochemicals and Antioxidant Activities
- Health Sciences › Medicine › Biochemistry (medical) › Antioxidant Activity and Oxidative Stress
- Keywords
- fruit and vegetable intake, biomarkers, dietary assessment, dietary intervention studies, compliance monitoring, carotenoids, vitamin C
- MeSH terms
- Ascorbic Acid, Beverages, Energy Intake, Carotenoids, Diet, Feeding Behavior, Fruit, Humans, Vegetables, Lutein, Biomarkers, Xanthophylls, Zeaxanthins, Cryptoxanthins
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