Cited by 378Vitamin D Research StudiesNutrition and Health StudiesAntioxidant Activity and Oxidative Stress

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Vitamin D Bioavailability: State of the Art

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Borel, P., Caillaud, D., Cano, N. J.·2015·Critical Reviews in Food Science and Nutrition

DOI 10.1080/10408398.2012.688897

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Abstract

There has been renewed interest in vitamin D since numerous recent studies have suggested that besides its well-established roles in bone metabolism and immunity, vitamin D status is inversely associated with the incidence of several diseases, e.g., cancers, cardio-vascular diseases, and neurodegenerative diseases. Surprisingly, there is very little data on factors that affect absorption of this fat-soluble vitamin, although it is acknowledged that dietary vitamin D could help to fight against the subdeficient vitamin D status that is common in several populations. This review describes the state of the art concerning the fate of vitamin D in the human upper gastrointestinal tract and on the factors assumed to affect its absorption efficiency. The main conclusions are: (i) ergocalciferol (vitamin D2), the form mostly used in supplements and fortified foods, is apparently absorbed with similar efficiency to cholecalciferol (vitamin D3, the main dietary form), (ii) 25-hydroxyvitamin D (25OHD), the metabolite produced in the liver, and which can be found in foods, is better absorbed than the nonhydroxy vitamin D forms cholecalciferol and ergocalciferol, (iii) the amount of fat with which vitamin D is ingested does not seem to significantly modify the bioavailability of vitamin D3, (iv) the food matrix has apparently little effect on vitamin D bioavailability, (v) sucrose polyesters (Olestra) and tetrahydrolipstatin (orlistat) probably diminish vitamin D absorption, and (vi) there is apparently no effect of aging on vitamin D absorption efficiency. We also find that there is insufficient, or even no data on the following factors suspected of affecting vitamin D bioavailability: (i) effect of type and amount of dietary fiber, (ii) effect of vitamin D status, and (iii) effect of genetic variation in proteins involved in its intestinal absorption. In conclusion, further studies are needed to improve our knowledge of factors affecting vitamin D absorption efficiency. Clinical studies with labeled vitamin D, e.g., deuterated or (13)C, are needed to accurately and definitively assess the effect of various factors on its bioavailability.

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Wortsman, J., Matsuoka, L. Y., Chen, T. C., Lu, Z., & Holick, M. F. (2000) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/72.3.690 · Cited by 3,204
Vitamin D2Is Much Less Effective than Vitamin D3in Humans
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Genome-wide association study of circulating vitamin D levels
Ahn, J., Yu, K. F., Stolzenberg‐Solomon, R. Z., Simon, K. C., McCullough, M. L., Gallicchio, L. M., Jacobs, E. J., Ascherio, A., Helzlsouer, K. J., Jacobs, K. B., et al. (2010) · Human Molecular Genetics · doi:10.1093/hmg/ddq155 · Cited by 810
Vitamin D2 Is as Effective as Vitamin D3 in Maintaining Circulating Concentrations of 25-Hydroxyvitamin D
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Volumetric Dilution, Rather Than Sequestration Best Explains the Low Vitamin D Status of Obesity
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Vitamin D and its Major Metabolites: Serum Levels after Graded Oral Dosing in Healthy Men
Barger-Lux, M. J., Heaney, R. P., Dowell, S. T., Chen, T. C., & Holick, M. F. (1998) · Osteoporosis International · doi:10.1007/s001980050058 · Cited by 356
THE FUNCTION OF BILE SALTS IN FAT ABSORPTION. THE SOLVENT PROPERTIES OF DILUTE MICELLAR SOLUTIONS OF CONJUGATED BILE SALTS
Hofmann, A. (1963) · Biochemical Journal · doi:10.1042/bj0890057 · Cited by 353
Short and Long-Term Variations in Serum Calciotropic Hormones after a Single Very Large Dose of Ergocalciferol (Vitamin D2) or Cholecalciferol (Vitamin D3) in the Elderly
Romagnoli, E., Mascia, M. L., Cipriani, C., Fassino, V., Mazzei, F., D'Erasmo, E., Carnevale, V., Scillitani, A., & Minisola, S. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-0350 · Cited by 335
Fortification of orange juice with vitamin D: a novel approach for enhancing vitamin D nutritional health
Tangpricha, V., Koutkia, P., Rieke, S. M., Chen, T. C., Perez, A. A., & Holick, M. F. (2003) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/77.6.1478 · Cited by 298
Class B Scavenger Receptor-Mediated Intestinal Absorption of Dietary β-Carotene and Cholesterol
van Bennekum, A., Werder, M., Thuahnai, S. T., Han, C.-H., Duong, P., Williams, D. L., Wettstein, P., Schulthess, G., Phillips, M. C., & Hauser, H. (2005) · Biochemistry · doi:10.1021/bi0484320 · Cited by 290

Show all 104 references

Research works printed but not linked: 14

Apukhovskaia L.I., 1990, Ukr. Biokhim. Zh., 62, 88
Barragry J.M., 1978, Clin. Sci. Mol. Med., 55, 213
de Pee S., 1996, Eur. J. Clin. Nutr., 50, S38
Hollander D., 1984, J. Lab. Clin. Med., 103, 462
Hollis B.W., 1996, J. Clin. Endocrinol. Metab., 81, 1385
10.1210/jc.2008-2012 · DOI
Maislos M., 1987, Isr. J. Med. Sci., 23, 1114
Schlagheck T.G., 1997, J. Nutr., 127
Szejtli J., 1983, Pharmazie, 38, 100
Tjellesen L., 1986, Bone Miner., 1, 407
van den Berg H, 1997, Eur. J. Clin. Nutr., 51, S76
Vellas B.J., 1991, Compr. Ther., 17, 46
West C.E., 1998, Internat. J. Vit. Nutr. Res., 68, 371
Wimalawansa S.J., 2012, Curr. Osteoporos. Rep.

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Vitamin D status, vitamin D intake, and sunlight exposure in adults adhering or not to periodic religious fasting for decades
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Wang, D., Yu, S., Zhang, Q., Cheng, Q., Xie, S., Zhang, Y., Guo, X., Zou, Y., Yin, Y., Yu, J., et al. (2021) · Journal of Mass Spectrometry · doi:10.1002/jms.4792 · Cited by 7
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Tian, M., Zeng, S., Cai, S., Reichetzeder, C., Zhang, X., Yin, C., Kuang, W., Cheng, K., Jiang, Y., Tao, M., et al. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.986848 · Cited by 7
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Jana, S. (2018) · Food Science & Nutrition Technology · doi:10.23880/fsnt-16000162 · Cited by 7
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Current recommendations in Poland for vitamin D supplementation.
Kuciński, J., Fryska, Z., Wołejko, A., Semeniuk, P., Burczyk, R., Górna, N., Łabuda, A., & Mazurek, E. (2023) · Medycyna Ogólna i Nauki o Zdrowiu · doi:10.26444/monz/176079 · Cited by 6
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Authors: Borel, P., Caillaud, D., & Cano, N. J.
Affiliations: Inserm (FR)
Centre Hospitalier Universitaire de Clermont-Ferrand (FR)
Université Clermont Auvergne (FR)
Corresponding author: Borel, P.
ORCID: Borel, P.
Caillaud, D.
Cano, N. J.
Venue: Critical Reviews in Food Science and Nutrition
Publisher: Informa UK Limited
Published: 2013-10-02
Volume: 55
Issue: 9
Pages: 1193-1205
ISSN: 1040-8398 (ISSN-L)
1549-7852
DOI: 10.1080/10408398.2012.688897
OpenAlex: W2029625174
Cited by: 378
References: 104
Citations by year: 2026: 30 · 2025: 48 · 2024: 47 · 2023: 55 · 2022: 41 · 2021: 42 · 2020: 31 · 2019: 25 · 2018: 25 · 2017: 13 · 2016: 12 · 2015: 7 · 2014: 2
FWCI: 5.22
Type: journal article
Language: en
Open access: green
inserm.hal.science
Licence: other-oa
Locations: Critical Reviews in Food Science and Nutrition (publishedVersion)
PubMed (publishedVersion)
HAL (submittedVersion, other-oa)
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Vitamin D Research Studies
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutrition and Health Studies
Health Sciences › Medicine › Biochemistry (medical) › Antioxidant Activity and Oxidative Stress
Keywords: vitamin D bioavailability, vitamin D absorption, upper gastrointestinal tract, vitamin D3, vitamin D2, 25-hydroxyvitamin D, fat-soluble vitamins, dietary fat, food matrix, olestra, orlistat, aging, dietary fiber, intestinal absorption, vitamin D status
MeSH terms: Orlistat, Aging, Biological Availability, Cholecalciferol, Ergocalciferols, Fatty Acids, Food, Fortified, Humans, Intestinal Absorption, Lactones, Risk Factors, Sucrose, Vitamin D, Dietary Supplements

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