The DOI matches its Crossref record; 180 of the 180 references it cites were found in a registry or an index.
Fruit Polyphenols: A Review of Anti-inflammatory Effects in Humans
Abstract
Underlying etiological factors in the development of obesity-related chronic diseases are long-term imbalances of oxidative and inflammatory stress leading to tissue dysfunction, damage, and ultimately failure. Poor dietary quality contributes significantly to the oxidative and inflammatory status of an individual. Conversely, various dietary approaches, including specific dietary factors can mitigate or prevent the occurrence of these risk-conferring imbalances brought about by modern lifestyle. Plant-derived polyphenolic compounds are well known for their antioxidant properties. Recent evidence indicates these compounds may confer anti-inflammatory and/or inflammatory response stabilizing activities, which would have important implications in health maintenance and disease risk reduction. Commonly consumed fruits, such as grapes, berries, and oranges/orange juice, contain polyphenolic compounds that have been studied for their effects on inflammation, but the nature and extent of their effects in humans remain unclear. Therefore, this article aims to provide a comprehensive overview of human clinical trials investigating the acute and chronic (feeding) effect of polyphenols from commonly consumed fruits or their derived products on inflammation.
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Cites
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Cited by
Wallace, T. C., Bailey, R. L., Blumberg, J. B., Burton-Freeman, B., Chen, C.-Y. O., Crowe-White, K. M., Drewnowski, A., Hooshmand, S., Johnson, E., Lewis, R., et al. (2020) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2019.1632258 · Cited by 638
Self-citationThe role of the gut microbiota in the metabolism of polyphenols as characterized by gnotobiotic mice
Pasinetti, G. M., Singh, R., Westfall, S., Herman, F., Faith, J., & Ho, L. (2018) · Journal of Alzheimer s Disease · doi:10.3233/jad-171151 · Cited by 112
Siddiqui, S. A., Ali Redha, A., Salauddin, M., Harahap, I. A., & Rupasinghe, H. P. V. (2025) · Critical Reviews in Analytical Chemistry · doi:10.1080/10408347.2023.2266846 · Cited by 110
Bounihi, A., Bitam, A., Bouazza, A., Yargui, L., & Koceir, E. A. (2017) · Pharmaceutical Biology · doi:10.1080/13880209.2016.1226369 · Cited by 50
Dimina, L., & Mariotti, F. (2019) · Nutrients · doi:10.3390/nu11091963 · Cited by 41
Metadata
- Authors
- Joseph, S. V., Edirisinghe, I., & Burton-Freeman, B. M.
- Venue
- Critical Reviews in Food Science and Nutrition
- Publisher
- Informa UK Limited
- Published
- 2015-01-23
- Volume
- 56
- Issue
- 3
- Pages
- 419-444
- ISSN
- 1040-8398 (ISSN-L)
- 1549-7852
- OpenAlex
- W1994579482
- Cited by
- 279
- References
- 180
- FWCI
- 10.65
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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